Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Rome from $650

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Rome departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Rome

Cheap round-trip flights

Enter your travel dates to find the best prices.
KLM Logo
6:50 pm - 10:45 pm
PTY
-
FCO
20h 55m
1 stop
KLM Logo
5:25 pm - 4:50 pm
FCO
-
PTY
30h 25m
1 stop
$695KLM
Mon, Apr 27 - Wed, May 6
Turkish Airlines Logo
10:20 pm - 6:25 pm
PTY
-
FCO
37h 05m
1 stop
Turkish Airlines Logo
7:05 am - 8:25 pm
FCO
-
PTY
20h 20m
1 stop
$709Turkish Airlines
Mon, Apr 27 - Wed, May 6
Turkish Airlines Logo
10:20 pm - 2:05 pm
PTY
-
FCO
32h 45m
1 stop
Turkish Airlines Logo
7:05 am - 6:25 pm
FCO
-
PTY
42h 20m
2 stops
$721Turkish Airlines
Mon, May 11 - Mon, May 25
Multiple Airlines Logo
2:27 pm - 10:50 am
PTY
-
FCO
37h 23m
1 stop
Multiple Airlines Logo
5:25 pm - 4:50 pm
FCO
-
PTY
30h 25m
1 stop
$728Multiple Airlines
Wed, Apr 29 - Sun, May 24
Multiple Airlines Logo
2:27 pm - 10:50 am
PTY
-
FCO
37h 23m
1 stop
Multiple Airlines Logo
5:25 pm - 4:50 pm
FCO
-
PTY
30h 25m
1 stop
$729Multiple Airlines
Wed, Apr 29 - Sun, May 24
Multiple Airlines Logo
2:27 pm - 10:50 am
PTY
-
FCO
37h 23m
1 stop
Multiple Airlines Logo
6:30 am - 4:50 pm
FCO
-
PTY
17h 20m
1 stop
$737Multiple Airlines
Wed, Apr 29 - Sun, May 24
Multiple Airlines Logo
6:50 pm - 10:45 pm
PTY
-
FCO
20h 55m
1 stop
Multiple Airlines Logo
10:00 am - 7:45 pm
FCO
-
PTY
16h 45m
1 stop
$742Multiple Airlines
Sun, May 31 - Thu, Jun 4
Turkish Airlines Logo
8:05 pm - 6:25 pm
PTY
-
FCO
39h 20m
1 stop
Turkish Airlines Logo
8:00 pm - 8:25 pm
FCO
-
PTY
31h 25m
1 stop
$743Turkish Airlines
Tue, May 26 - Sun, Jun 28
Air Europa Logo
8:25 pm - 9:30 am
PTY
-
FCO
30h 05m
1 stop
Air Europa Logo
10:30 am - 6:40 pm
FCO
-
PTY
15h 10m
1 stop
$761Air Europa
Sat, May 9 - Wed, May 27
Turkish Airlines Logo
8:05 pm - 6:25 pm
PTY
-
FCO
39h 20m
1 stop
Turkish Airlines Logo
3:10 pm - 8:25 pm
FCO
-
PTY
36h 15m
1 stop
$772Turkish Airlines
Tue, May 26 - Sun, Jun 28

KLM flights from Panama City to Rome

Our best KLM deals on Panama City to Rome flight tickets
KLM
Apr 27
PTY6:50 pmPanama City Tocumen Intl
20h 55m
1 stop
FCO10:45 pmRome Fiumicino
May 6
FCO5:25 pmRome Fiumicino
30h 25m
1 stop
PTY4:50 pmPanama City Tocumen Intl
$695
KLM
Mar 4
PTY6:45 pmPanama City Tocumen Intl
22h 25m
1 stop
FCO11:10 pmRome Fiumicino
Mar 11
FCO5:15 pmRome Fiumicino
29h 15m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$801
KLM
May 10
PTY6:50 pmPanama City Tocumen Intl
20h 55m
1 stop
FCO10:45 pmRome Fiumicino
May 26
FCO10:35 amRome Fiumicino
37h 15m
1 stop
PTY4:50 pmPanama City Tocumen Intl
$838

Turkish Airlines flights from Panama City to Rome

Our best Turkish Airlines deals on Panama City to Rome flight tickets
Turkish Airlines
Apr 27
PTY10:20 pmPanama City Tocumen Intl
37h 05m
1 stop
FCO6:25 pmRome Fiumicino
May 6
FCO7:05 amRome Fiumicino
20h 20m
1 stop
PTY8:25 pmPanama City Tocumen Intl
$709
Turkish Airlines
May 11
PTY10:20 pmPanama City Tocumen Intl
32h 45m
1 stop
FCO2:05 pmRome Fiumicino
May 25
FCO7:05 amRome Fiumicino
42h 20m
2 stops
PTY6:25 pmPanama City Tocumen Intl
$721
Turkish Airlines
May 26
PTY8:05 pmPanama City Tocumen Intl
39h 20m
1 stop
FCO6:25 pmRome Fiumicino
Jun 28
FCO8:00 pmRome Fiumicino
31h 25m
1 stop
PTY8:25 pmPanama City Tocumen Intl
$743

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 4/27

6:50 pm-10:45 pm

1 stop20h 55m

Rome Fiumicino

Wed 5/6

5:25 pm-4:50 pm

1 stop30h 25m

$695

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 4/27

10:20 pm-6:25 pm

1 stop37h 05m

Rome Fiumicino

Wed 5/6

7:05 am-8:25 pm

1 stop20h 20m

$709

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 5/11

10:20 pm-2:05 pm

1 stop32h 45m

Rome Fiumicino

Mon 5/25

7:05 am-6:25 pm

2 stops42h 20m

$721

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 4/29

2:27 pm-10:50 am

1 stop37h 23m

Rome Fiumicino

Sun 5/24

5:25 pm-4:50 pm

1 stop30h 25m

$728

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 4/29

2:27 pm-10:50 am

1 stop37h 23m

Rome Fiumicino

Sun 5/24

5:25 pm-4:50 pm

1 stop30h 25m

$729

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 4/29

2:27 pm-10:50 am

1 stop37h 23m

Rome Fiumicino

Sun 5/24

6:30 am-4:50 pm

1 stop17h 20m

$737

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 5/31

6:50 pm-10:45 pm

1 stop20h 55m

Rome Fiumicino

Thu 6/4

10:00 am-7:45 pm

1 stop16h 45m

$742

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 5/26

8:05 pm-6:25 pm

1 stop39h 20m

Rome Fiumicino

Sun 6/28

8:00 pm-8:25 pm

1 stop31h 25m

$743

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 5/9

8:25 pm-9:30 am

1 stop30h 05m

Rome Fiumicino

Wed 5/27

10:30 am-6:40 pm

1 stop15h 10m

$761

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 5/26

8:05 pm-6:25 pm

1 stop39h 20m

Rome Fiumicino

Sun 6/28

3:10 pm-8:25 pm

1 stop36h 15m

$772

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Rome from

How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Panama City is in April. Flight prices, which tend to average around $754, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of April, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $789.

How far in advance should I book a flight to Rome?

You are more likely to see cheaper flights to Rome from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $850 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from Panama City for as low as $690 on momondo.

How have Panama City to Rome flight prices changed over time?

As of February 2026, prices for Panama City to Rome flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Rome according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Fastest flight time

14h 00m

Direct flights

None
The fastest flight from Panama City to Rome takes 14h 00m
There are no direct flights from Panama City to Rome. There are no popular flight routes from Panama City to Rome.
Search flight deals

  • How far is Panama City Tocumen Intl to Rome by plane?

    Rome is 5903.6 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 14h 00m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

    Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.

  • What documentation or ID do you need to fly to Rome?

    The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Rome?

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo
Airline
Rating
Free Cancellation
Price
Air EuropaPriceFrom $679Free CancellationRating
6.9
590 reviews
Search Air Europa flights
Turkish AirlinesPriceFrom $690Free CancellationRating
7.3
4,239 reviews
Search Turkish Airlines flights
Air FrancePriceFrom $818Free CancellationRating
7.4
1,541 reviews
Search Air France flights

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Cassino
Ponza
Gaeta
Montepulciano
Pienza
Tivoli
Orvieto
Sperlonga
Chianciano Terme
Terracina
Saturnia
Santa Marinella
Ciampino
Sabaudia
Grosseto
Ascoli Piceno
Cortona
Orbetello

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Rome for you.

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

momondo does allow users to show only those flights to Rome from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Rome?

momondo provides multiple filters to help you find the best flight to Rome from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Rome, momondo offers a useful price alert feature which will track prices for flights to Rome from Panama City and alert you when they change.

An easier way to manage your Rome trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 3/30
Mon 4/6
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome
Rome Ciampino Airport
Rome Fiumicino Airport