Which layover airport has the shortest connection time from Panama City to Rome?

Madrid (MAD) has the shortest average layover time for this route: 1h 53m.

What is the cheapest airline that flies from Panama City Tocumen Intl to Rome?

Air France, Turkish Airlines, and United Airlines are the most popular carriers operating from Panama City Tocumen Intl to Rome

What airlines fly to Rome?

Air France, Air Europa and Turkish Airlines are the top three most popular airlines that fly to Rome from Panama City according to our data. Air France is the first choice among our users, with 30% of people opting to fly with this airline when traveling to Rome. Keep in mind that there are 4 different airlines that fly to Rome on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Panama City to Rome?

Flights via Istanbul (IST) offer the lowest average round-trip price of $803.

Which layover airport has the shortest travel time from Panama City to Rome?

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 00m.

Which airport is the most popular layover for flights between Panama City and Rome?

Madrid (MAD) was the most common stop: 65% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

There are 4 operators available for flights from Panama City Tocumen Intl Airport to Rome as of August 2025.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.

What documentation or ID do you need to fly to Rome?

The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$485 Cheap Flights from Panama City to Rome in 2025

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Round-trip

One-way

Last minute

Cheap round-trip flights

11:05 am - 4:55 pmPTY-FCO

22h 50m1 stop

8:20 am - 2:40 amFCO-PTY

25h 20m1 stop

$609Condor

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Thu, Sep 18 - Wed, Sep 24

11:05 am - 4:55 pmPTY-FCO

22h 50m1 stop

8:20 am - 2:40 amFCO-PTY

25h 20m1 stop

$640Condor

Find Deal

Thu, Sep 18 - Wed, Sep 24

9:55 pm - 11:30 pmPTY-FCO

18h 35m1 stop

10:45 am - 8:00 pmFCO-PTY

40h 15m1 stop

$707Turkish Airlines

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Wed, Oct 8 - Tue, Oct 14

9:45 pm - 9:50 amPTY-FCO

30h 05m1 stop

11:15 am - 5:05 pmFCO-PTY

35h 50m2 stops

$732Turkish Airlines

Find Deal

Mon, Nov 3 - Mon, Nov 17

8:25 pm - 5:25 pmPTY-FCO

14h 00m1 stop

10:30 am - 6:40 pmFCO-PTY

15h 10m1 stop

$876Air Europa

Find Deal

Sat, Sep 20 - Mon, Oct 6

8:25 pm - 9:30 amPTY-FCO

30h 05m1 stop

6:25 pm - 7:45 pmFCO-PTY

31h 20m1 stop

$877Air Europa

Find Deal

Sun, Oct 12 - Wed, Oct 29

7:55 pm - 8:55 amPTY-FCO

30h 00m1 stop

6:25 pm - 5:45 pmFCO-PTY

30h 20m1 stop

$892Air France

Find Deal

Mon, Sep 15 - Wed, Sep 24

7:55 pm - 8:55 amPTY-FCO

30h 00m1 stop

6:05 am - 5:45 pmFCO-PTY

18h 40m1 stop

$905Air France

Find Deal

Tue, Sep 9 - Thu, Sep 25

3:35 pm - 1:40 pmPTY-FCO

39h 05m1 stop

11:30 am - 1:50 pmFCO-PTY

33h 20m2 stops

$914United Airlines

Find Deal

Mon, Oct 6 - Fri, Oct 17

3:30 pm - 1:15 pmPTY-FCO

38h 45m2 stops

3:20 pm - 1:50 pmFCO-PTY

29h 30m2 stops

$917United Airlines

Find Deal

Fri, Sep 12 - Wed, Sep 24

United Airlines flights from Panama City to Rome

Our best United Airlines deals on Panama City to Rome flight tickets

United Airlines

Oct 6

PTY3:35 pmPanama City Tocumen Intl

39h 05m

1 stop

FCO1:40 pmRome Fiumicino

Oct 17

FCO11:30 amRome Fiumicino

33h 20m

2 stops

PTY1:50 pmPanama City Tocumen Intl

$914

Find similar

United Airlines

Sep 12

PTY3:30 pmPanama City Tocumen Intl

38h 45m

2 stops

FCO1:15 pmRome Fiumicino

Sep 24

FCO3:20 pmRome Fiumicino

29h 30m

2 stops

PTY1:50 pmPanama City Tocumen Intl

$917

Find similar

United Airlines

Jan 13

PTY4:40 pmPanama City Tocumen Intl

57h 50m

2 stops

FCO8:30 amRome Fiumicino

Jan 22

FCO12:45 pmRome Fiumicino

32h 00m

2 stops

PTY2:45 pmPanama City Tocumen Intl

$923

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Air France flights from Panama City to Rome

Our best Air France deals on Panama City to Rome flight tickets

Air France

Sep 15

PTY7:55 pmPanama City Tocumen Intl

30h 00m

1 stop

FCO8:55 amRome Fiumicino

Sep 24

FCO6:25 pmRome Fiumicino

30h 20m

1 stop

PTY5:45 pmPanama City Tocumen Intl

$892

Find similar

Air France

Sep 9

PTY7:55 pmPanama City Tocumen Intl

30h 00m

1 stop

FCO8:55 amRome Fiumicino

Sep 25

FCO6:05 amRome Fiumicino

18h 40m

1 stop

PTY5:45 pmPanama City Tocumen Intl

$905

Find similar

Air France

Sep 9

PTY7:55 pmPanama City Tocumen Intl

30h 00m

1 stop

FCO8:55 amRome Fiumicino

Sep 24

FCO3:50 pmRome Fiumicino

32h 55m

1 stop

PTY5:45 pmPanama City Tocumen Intl

$918

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 9/18

11:05 am-4:55 pm

1 stop22h 50m

Rome Fiumicino

Wed 9/24

8:20 am-2:40 am

1 stop25h 20m

$609

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 9/18

11:05 am-4:55 pm

1 stop22h 50m

Rome Fiumicino

Wed 9/24

8:20 am-2:40 am

1 stop25h 20m

$640

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 10/8

9:55 pm-11:30 pm

1 stop18h 35m

Rome Fiumicino

Tue 10/14

10:45 am-8:00 pm

1 stop40h 15m

$707

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 11/3

9:45 pm-9:50 am

1 stop30h 05m

Rome Fiumicino

Mon 11/17

11:15 am-5:05 pm

2 stops35h 50m

$732

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 9/20

8:25 pm-5:25 pm

1 stop14h 00m

Rome Fiumicino

Mon 10/6

10:30 am-6:40 pm

1 stop15h 10m

$876

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 10/12

8:25 pm-9:30 am

1 stop30h 05m

Rome Fiumicino

Wed 10/29

6:25 pm-7:45 pm

1 stop31h 20m

$877

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 9/15

7:55 pm-8:55 am

1 stop30h 00m

Rome Fiumicino

Wed 9/24

6:25 pm-5:45 pm

1 stop30h 20m

$892

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 9/9

7:55 pm-8:55 am

1 stop30h 00m

Rome Fiumicino

Thu 9/25

6:05 am-5:45 pm

1 stop18h 40m

$905

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 10/6

3:35 pm-1:40 pm

1 stop39h 05m

Rome Fiumicino

Fri 10/17

11:30 am-1:50 pm

2 stops33h 20m

$914

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Fri 9/12

3:30 pm-1:15 pm

2 stops38h 45m

Rome Fiumicino

Wed 9/24

3:20 pm-1:50 pm

2 stops29h 30m

$917

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Panama City is in March. Flight prices, which tend to average around $792, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of March, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $797.

What is the cheapest day to depart on your flight to Rome?

The cheapest day to depart on your flight to Rome is on a Wednesday when prices can be found for as low as $818. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Rome on Saturday is $972.

What is the cheapest time of day to depart on your flight to Rome?

In the morning is the cheapest time of day to fly from Panama City to Rome when you can find flight prices for as low as $878. Flying to Rome in the morning is an ideal time because this is during off-peak travel hours. Flights to Rome are more costly in the evening, with an average ticket price of $914. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Rome?

You are more likely to see cheaper flights to Rome from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $858 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from Panama City for as low as $758 on momondo.

How have Panama City to Rome flight prices changed over time?

As of August 2025, prices for Panama City to Rome flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Rome according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Best Price Found	$485
Fastest flight time	14h 00m
Direct flights	None
Airports in Rome	1 airport

The best one-way flight to Rome from Panama City in the past 72 hours is $485. The best round-trip flight deal from Panama City to Rome found on momondo in the last 72 hours is $609.

The fastest flight from Panama City to Rome takes 14h 00m

There are no direct flights from Panama City to Rome. Popular non-direct route for this connection is Panama City Tocumen Intl Airport - Rome Fiumicino Airport.

There is 1 airport near Rome: Rome Fiumicino (FCO)

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How far is Panama City Tocumen Intl to Rome by plane?
Rome is 5903.6 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 14h 00m.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?
Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?
There are 4 operators available for flights from Panama City Tocumen Intl Airport to Rome as of August 2025.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.
What documentation or ID do you need to fly to Rome?
The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Panama City to Rome?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Panama City to Rome is Air Europa (40% of total bookings). The next most popular airlines are Air France (26%), Turkish Airlines (15%), and United Airlines (11%).

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo

Airline	Rating	Free Cancellation	Price
Turkish Airlines	PriceFrom $692	Free Cancellation	Rating 7.3 3,935 reviews	Search Turkish Airlines flights
Air Europa	PriceFrom $746	Free Cancellation	Rating 7.0 542 reviews	Search Air Europa flights
Iberia	PriceFrom $747	Free Cancellation	Rating 7.0 2,865 reviews	Search Iberia flights
Air France	PriceFrom $818	Free Cancellation	Rating 7.5 1,466 reviews	Search Air France flights

Fiumicino

Civitavecchia

Cassino

Pienza

Ponza

Ciampino

Montepulciano

Tivoli

Gaeta

Sperlonga

Santa Marinella

Cortona

Orvieto

Grosseto

Saturnia

Anzio

Sabaudia

Terracina

Ascoli Piceno

Foligno

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Rome for you.

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

momondo does allow users to show only those flights to Rome from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Rome?

momondo provides multiple filters to help you find the best flight to Rome from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Rome, momondo offers a useful price alert feature which will track prices for flights to Rome from Panama City and alert you when they change.

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Cheap flights from Panama City to Rome from $485

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Rome departing on 10/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Panama City to Rome

Our best United Airlines deals on Panama City to Rome flight tickets

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How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Rome?

What is the cheapest day to depart on your flight to Rome?

What is the cheapest time of day to depart on your flight to Rome?

How far in advance should I book a flight to Rome?

How have Panama City to Rome flight prices changed over time?

As of August 2025, prices for Panama City to Rome flights are approximately 18% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Rome?

Air France, Turkish Airlines, and United Airlines are the most popular carriers operating from Panama City Tocumen Intl to Rome

What airlines fly to Rome?

Which airport is the most popular layover for flights between Panama City and Rome?

Madrid (MAD) was the most common stop: 65% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Panama City to Rome?

Flights via Istanbul (IST) offer the lowest average round-trip price of $803.

Which layover airport has the shortest travel time from Panama City to Rome?

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 00m.

Which layover airport has the shortest connection time from Panama City to Rome?

Madrid (MAD) has the shortest average layover time for this route: 1h 53m.

When to book flights from Panama City to Rome

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Best Price Found

Fastest flight time

Direct flights

Airports in Rome

How far is Panama City Tocumen Intl to Rome by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

What documentation or ID do you need to fly to Rome?

What is the most popular airline from Panama City to Rome?

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo

Traveling to a place near Rome?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Rome?

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

An easier way to manage your Rome trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome