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Cheap flights from Panama City to Rome from $506

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Rome departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Rome

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
8:05 pm - 6:25 pm
PTY
-
FCO
39h 20m
1 stop
Turkish Airlines Logo
10:45 am - 6:30 pm
FCO
-
PTY
38h 45m
2 stops
$730Turkish Airlines
Tue, Apr 28 - Fri, May 15
Multiple Airlines Logo
6:50 pm - 9:35 am
PTY
-
FCO
31h 45m
1 stop
Multiple Airlines Logo
12:30 pm - 7:45 pm
FCO
-
PTY
14h 15m
1 stop
$731Multiple Airlines
Tue, Jun 2 - Thu, Jun 11
Turkish Airlines Logo
9:45 pm - 1:50 pm
PTY
-
FCO
34h 05m
1 stop
Turkish Airlines Logo
6:45 am - 5:05 pm
FCO
-
PTY
40h 20m
2 stops
$732Turkish Airlines
Wed, Feb 18 - Wed, Mar 4
Multiple Airlines Logo
9:55 pm - 11:15 pm
PTY
-
FCO
18h 20m
1 stop
Multiple Airlines Logo
5:25 pm - 4:50 pm
FCO
-
PTY
30h 25m
1 stop
$735Multiple Airlines
Mon, May 18 - Sat, May 30
Turkish Airlines Logo
6:45 pm - 6:20 pm
PTY
-
FCO
17h 35m
1 stop
Turkish Airlines Logo
6:45 am - 5:05 pm
FCO
-
PTY
40h 20m
2 stops
$742Turkish Airlines
Thu, Feb 12 - Wed, Feb 18
Air Europa Logo
8:25 pm - 5:25 pm
PTY
-
FCO
14h 00m
1 stop
Air Europa Logo
10:30 am - 6:40 pm
FCO
-
PTY
15h 10m
1 stop
$743Air Europa
Tue, Apr 21 - Sat, Apr 25
Turkish Airlines Logo
9:45 pm - 9:55 pm
PTY
-
FCO
18h 10m
1 stop
Turkish Airlines Logo
6:45 am - 7:50 pm
FCO
-
PTY
19h 05m
1 stop
$748Turkish Airlines
Mon, Feb 23 - Sat, Mar 7
Multiple Airlines Logo
6:50 pm - 10:45 pm
PTY
-
FCO
20h 55m
1 stop
Multiple Airlines Logo
6:05 am - 4:50 pm
FCO
-
PTY
17h 45m
2 stops
$751Multiple Airlines
Tue, Jun 2 - Tue, Jun 9
Multiple Airlines Logo
6:50 pm - 11:45 am
PTY
-
FCO
33h 55m
1 stop
Multiple Airlines Logo
6:05 am - 4:50 pm
FCO
-
PTY
17h 45m
2 stops
$752Multiple Airlines
Tue, Jun 2 - Tue, Jun 9
Turkish Airlines Logo
9:45 pm - 1:50 pm
PTY
-
FCO
34h 05m
1 stop
Turkish Airlines Logo
10:50 am - 5:05 pm
FCO
-
PTY
36h 15m
2 stops
$753Turkish Airlines
Wed, Feb 11 - Wed, Mar 4

Turkish Airlines flights from Panama City to Rome

Our best Turkish Airlines deals on Panama City to Rome flight tickets
Turkish Airlines
Apr 28
PTY8:05 pmPanama City Tocumen Intl
39h 20m
1 stop
FCO6:25 pmRome Fiumicino
May 15
FCO10:45 amRome Fiumicino
38h 45m
2 stops
PTY6:30 pmPanama City Tocumen Intl
$730
Turkish Airlines
Feb 18
PTY9:45 pmPanama City Tocumen Intl
34h 05m
1 stop
FCO1:50 pmRome Fiumicino
Mar 4
FCO6:45 amRome Fiumicino
40h 20m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$732
Turkish Airlines
Feb 12
PTY6:45 pmPanama City Tocumen Intl
17h 35m
1 stop
FCO6:20 pmRome Fiumicino
Feb 18
FCO6:45 amRome Fiumicino
40h 20m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$742

Air Europa flights from Panama City to Rome

Our best Air Europa deals on Panama City to Rome flight tickets
Air Europa
Apr 21
PTY8:25 pmPanama City Tocumen Intl
14h 00m
1 stop
FCO5:25 pmRome Fiumicino
Apr 25
FCO10:30 amRome Fiumicino
15h 10m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$743
Air Europa
Mar 31
PTY8:25 pmPanama City Tocumen Intl
14h 00m
1 stop
FCO5:25 pmRome Fiumicino
May 2
FCO10:30 amRome Fiumicino
15h 10m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$764
Air Europa
Apr 29
PTY8:25 pmPanama City Tocumen Intl
14h 00m
1 stop
FCO5:25 pmRome Fiumicino
May 3
FCO10:30 amRome Fiumicino
15h 10m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$765

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 4/28

8:05 pm-6:25 pm

1 stop39h 20m

Rome Fiumicino

Fri 5/15

10:45 am-6:30 pm

2 stops38h 45m

$730

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 6/2

6:50 pm-9:35 am

1 stop31h 45m

Rome Fiumicino

Thu 6/11

12:30 pm-7:45 pm

1 stop14h 15m

$731

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 2/18

9:45 pm-1:50 pm

1 stop34h 05m

Rome Fiumicino

Wed 3/4

6:45 am-5:05 pm

2 stops40h 20m

$732

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 5/18

9:55 pm-11:15 pm

1 stop18h 20m

Rome Fiumicino

Sat 5/30

5:25 pm-4:50 pm

1 stop30h 25m

$735

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 2/12

6:45 pm-6:20 pm

1 stop17h 35m

Rome Fiumicino

Wed 2/18

6:45 am-5:05 pm

2 stops40h 20m

$742

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 4/21

8:25 pm-5:25 pm

1 stop14h 00m

Rome Fiumicino

Sat 4/25

10:30 am-6:40 pm

1 stop15h 10m

$743

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 2/23

9:45 pm-9:55 pm

1 stop18h 10m

Rome Fiumicino

Sat 3/7

6:45 am-7:50 pm

1 stop19h 05m

$748

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 6/2

6:50 pm-10:45 pm

1 stop20h 55m

Rome Fiumicino

Tue 6/9

6:05 am-4:50 pm

2 stops17h 45m

$751

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 6/2

6:50 pm-11:45 am

1 stop33h 55m

Rome Fiumicino

Tue 6/9

6:05 am-4:50 pm

2 stops17h 45m

$752

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 2/11

9:45 pm-1:50 pm

1 stop34h 05m

Rome Fiumicino

Wed 3/4

10:50 am-5:05 pm

2 stops36h 15m

$753

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Rome from

How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Rome?

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Panama City is in May. Flight prices, which tend to average around $789, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of May, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $796.

How far in advance should I book a flight to Rome?

You are more likely to see cheaper flights to Rome from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $835 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from Panama City for as low as $690 on momondo.

How have Panama City to Rome flight prices changed over time?

As of January 2026, prices for Panama City to Rome flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Rome according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Fastest flight time

18h 20m

Direct flights

None
The fastest flight from Panama City to Rome takes 18h 20m
There are no direct flights from Panama City to Rome. There are no popular flight routes from Panama City to Rome.
Search flight deals

  • How far is Panama City Tocumen Intl to Rome by plane?

    Rome is 5903.6 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 18h 20m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

    Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.

  • What documentation or ID do you need to fly to Rome?

    The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Rome?

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo
Airline
Rating
Free Cancellation
Price
Air EuropaPriceFrom $679Free CancellationRating
6.9
588 reviews
Search Air Europa flights
Turkish AirlinesPriceFrom $690Free CancellationRating
7.3
4,183 reviews
Search Turkish Airlines flights
IberiaPriceFrom $767Free CancellationRating
7.0
3,087 reviews
Search Iberia flights
Air FrancePriceFrom $818Free CancellationRating
7.4
1,522 reviews
Search Air France flights

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Cassino
Pienza
Montepulciano
Ponza
Tivoli
Sperlonga
Gaeta
Orvieto
Chianciano Terme
Cortona
Terracina
Ciampino
Santa Marinella
Grosseto
Sabaudia
Ascoli Piceno
Saturnia
Orbetello

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Rome for you.

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

momondo does allow users to show only those flights to Rome from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Rome?

momondo provides multiple filters to help you find the best flight to Rome from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Rome, momondo offers a useful price alert feature which will track prices for flights to Rome from Panama City and alert you when they change.

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Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome
Rome Ciampino Airport
Rome Fiumicino Airport