What is the cheapest airline that flies from Panama City Tocumen Intl to Rome?

Air Europa, Air France, and Iberia are the most popular carriers operating from Panama City Tocumen Intl to Rome

Which airport is the most popular layover for flights between Panama City and Rome?

Madrid (MAD) was the most common stop: 57% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Panama City to Rome?

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 00m.

Which layover airport offers the lowest fares from Panama City to Rome?

Flights via Paris (CDG) offer the lowest average round-trip price of $830.

Which layover airport has the shortest connection time from Panama City to Rome?

Madrid (MAD) has the shortest average layover time for this route: 1h 53m.

What airlines fly to Rome?

Air France, Air Europa and Turkish Airlines are the top three most popular airlines that fly to Rome from Panama City according to our data. Air France is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Rome. Keep in mind that there are 4 different airlines that fly to Rome on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

There are 4 operators available for flights from Panama City Tocumen Intl Airport to Rome as of October 2025.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.

What documentation or ID do you need to fly to Rome?

The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$529 Cheap Flights from Panama City to Rome in 2025/26

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9:45 pm - 1:50 pmPTY-FCO

34h 05m1 stop

2:50 pm - 7:50 pmFCO-PTY

35h 00m1 stop

$726Turkish Airlines

Find Deal

Wed, Nov 19 - Sun, Nov 23

9:45 pm - 9:55 pmPTY-FCO

18h 10m1 stop

6:45 am - 7:50 pmFCO-PTY

19h 05m1 stop

$727Turkish Airlines

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Sat, Nov 22 - Sat, Nov 29

10:05 pm - 11:10 pmPTY-FCO

19h 05m1 stop

5:15 pm - 4:30 pmFCO-PTY

29h 15m1 stop

$754KLM

Find Deal

Mon, Feb 2 - Sat, Feb 7

6:50 pm - 10:45 pmPTY-FCO

20h 55m1 stop

6:10 am - 4:30 pmFCO-PTY

16h 20m1 stop

$821KLM

Find Deal

Sun, Oct 19 - Wed, Jan 14

10:20 pm - 7:45 pmPTY-FCO

15h 25m1 stop

4:20 pm - 8:10 pmFCO-PTY

33h 50m1 stop

$845Air France

Find Deal

Mon, Dec 15 - Sat, Mar 14

10:20 pm - 10:45 pmPTY-FCO

18h 25m1 stop

8:45 pm - 8:10 pmFCO-PTY

29h 25m1 stop

$853Air France

Find Deal

Wed, Oct 29 - Thu, Nov 6

9:30 pm - 9:30 amPTY-FCO

30h 00m1 stop

10:30 am - 7:45 pmFCO-PTY

15h 15m1 stop

$858Air Europa

Find Deal

Sat, Mar 7 - Wed, Mar 18

9:30 pm - 5:25 pmPTY-FCO

13h 55m1 stop

10:30 am - 7:45 pmFCO-PTY

15h 15m1 stop

$910Air Europa

Find Deal

Sun, Mar 15 - Thu, Mar 19

10:00 am - 7:55 amPTY-FCO

15h 55m1 stop

12:55 pm - 2:45 pmFCO-PTY

31h 50m2 stops

$919United Airlines

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Tue, Nov 4 - Tue, Nov 11

4:41 pm - 8:30 amPTY-FCO

33h 49m2 stops

12:50 pm - 7:38 pmFCO-PTY

60h 48m2 stops

$924United Airlines

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Fri, Dec 12 - Thu, Jan 15

KLM flights from Panama City to Rome

Our best KLM deals on Panama City to Rome flight tickets

KLM

Feb 2

PTY10:05 pmPanama City Tocumen Intl

19h 05m

1 stop

FCO11:10 pmRome Fiumicino

Feb 7

FCO5:15 pmRome Fiumicino

29h 15m

1 stop

PTY4:30 pmPanama City Tocumen Intl

$754

Find similar

KLM

Oct 19

PTY6:50 pmPanama City Tocumen Intl

20h 55m

1 stop

FCO10:45 pmRome Fiumicino

Jan 14

FCO6:10 amRome Fiumicino

16h 20m

1 stop

PTY4:30 pmPanama City Tocumen Intl

$821

Find similar

KLM

Oct 21

PTY6:50 pmPanama City Tocumen Intl

20h 55m

1 stop

FCO10:45 pmRome Fiumicino

Mar 10

FCO8:25 pmRome Fiumicino

26h 05m

1 stop

PTY4:30 pmPanama City Tocumen Intl

$906

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Air Europa flights from Panama City to Rome

Our best Air Europa deals on Panama City to Rome flight tickets

Air Europa

Mar 7

PTY9:30 pmPanama City Tocumen Intl

30h 00m

1 stop

FCO9:30 amRome Fiumicino

Mar 18

FCO10:30 amRome Fiumicino

15h 15m

1 stop

PTY7:45 pmPanama City Tocumen Intl

$858

Find similar

Air Europa

Mar 15

PTY9:30 pmPanama City Tocumen Intl

13h 55m

1 stop

FCO5:25 pmRome Fiumicino

Mar 19

FCO10:30 amRome Fiumicino

15h 15m

1 stop

PTY7:45 pmPanama City Tocumen Intl

$910

Find similar

Air Europa

Oct 22

PTY8:25 pmPanama City Tocumen Intl

30h 05m

1 stop

FCO9:30 amRome Fiumicino

Oct 27

FCO2:35 pmRome Fiumicino

35h 10m

1 stop

PTY7:45 pmPanama City Tocumen Intl

$3,073

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 11/19

9:45 pm-1:50 pm

1 stop34h 05m

Rome Fiumicino

Sun 11/23

2:50 pm-7:50 pm

1 stop35h 00m

$726

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 11/22

9:45 pm-9:55 pm

1 stop18h 10m

Rome Fiumicino

Sat 11/29

6:45 am-7:50 pm

1 stop19h 05m

$727

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 2/2

10:05 pm-11:10 pm

1 stop19h 05m

Rome Fiumicino

Sat 2/7

5:15 pm-4:30 pm

1 stop29h 15m

$754

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 10/19

6:50 pm-10:45 pm

1 stop20h 55m

Rome Fiumicino

Wed 1/14

6:10 am-4:30 pm

1 stop16h 20m

$821

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 12/15

10:20 pm-7:45 pm

1 stop15h 25m

Rome Fiumicino

Sat 3/14

4:20 pm-8:10 pm

1 stop33h 50m

$845

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 10/29

10:20 pm-10:45 pm

1 stop18h 25m

Rome Fiumicino

Thu 11/6

8:45 pm-8:10 pm

1 stop29h 25m

$853

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 3/7

9:30 pm-9:30 am

1 stop30h 00m

Rome Fiumicino

Wed 3/18

10:30 am-7:45 pm

1 stop15h 15m

$858

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 3/15

9:30 pm-5:25 pm

1 stop13h 55m

Rome Fiumicino

Thu 3/19

10:30 am-7:45 pm

1 stop15h 15m

$910

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 11/4

10:00 am-7:55 am

1 stop15h 55m

Rome Fiumicino

Tue 11/11

12:55 pm-2:45 pm

2 stops31h 50m

$919

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Fri 12/12

4:41 pm-8:30 am

2 stops33h 49m

Rome Fiumicino

Thu 1/15

12:50 pm-7:38 pm

2 stops60h 48m

$924

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How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Panama City is in March. Flight prices, which tend to average around $786, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of March, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $795.

What is the cheapest day to depart on your flight to Rome?

The cheapest day to depart on your flight to Rome is on a Wednesday when prices can be found for as low as $818. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Rome on Saturday is $972.

What is the cheapest time of day to depart on your flight to Rome?

In the morning is the cheapest time of day to fly from Panama City to Rome when you can find flight prices for as low as $878. Flying to Rome in the morning is an ideal time because this is during off-peak travel hours. Flights to Rome are more costly in the evening, with an average ticket price of $914. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Rome?

You are more likely to see cheaper flights to Rome from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $838 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from Panama City for as low as $728 on momondo.

How have Panama City to Rome flight prices changed over time?

As of October 2025, prices for Panama City to Rome flights are approximately 40% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Rome according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Direct flights	None

There are no direct flights from Panama City to Rome. There are no popular flight routes from Panama City to Rome.

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How far is Panama City Tocumen Intl to Rome by plane?
Rome is 5903.6 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 13h 55m.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?
Prices for flights from Panama City Tocumen Intl Airport to Rome are refreshed on a daily basis.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?
There are 4 operators available for flights from Panama City Tocumen Intl Airport to Rome as of October 2025.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Rome.
What documentation or ID do you need to fly to Rome?
The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Panama City to Rome?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Panama City to Rome is Air Europa (45% of total bookings). The next most popular airlines are Air France (23%), Turkish Airlines (20%), and United Airlines (12%).

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo

Airline	Rating	Free Cancellation	Price
Air Europa	PriceFrom $679	Free Cancellation	Rating 7.0 563 reviews	Search Air Europa flights
Turkish Airlines	PriceFrom $690	Free Cancellation	Rating 7.3 3,996 reviews	Search Turkish Airlines flights
Iberia	PriceFrom $767	Free Cancellation	Rating 7.0 2,982 reviews	Search Iberia flights
Air France	PriceFrom $818	Free Cancellation	Rating 7.4 1,467 reviews	Search Air France flights

Fiumicino

Civitavecchia

Cassino

Pienza

Ponza

Gaeta

Tivoli

Sperlonga

Ciampino

Montepulciano

Orvieto

Cortona

Terracina

Ascoli Piceno

Santa Marinella

Grosseto

Sabaudia

Saturnia

Anzio

Chianciano Terme

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Rome for you.

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

momondo does allow users to show only those flights to Rome from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Rome?

momondo provides multiple filters to help you find the best flight to Rome from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Rome, momondo offers a useful price alert feature which will track prices for flights to Rome from Panama City and alert you when they change.

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Cheap flights from Panama City to Rome from $529

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Rome departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Panama City to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Rome?

What is the cheapest day to depart on your flight to Rome?

What is the cheapest time of day to depart on your flight to Rome?

How far in advance should I book a flight to Rome?

How have Panama City to Rome flight prices changed over time?

As of October 2025, prices for Panama City to Rome flights are approximately 40% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Rome?

Air Europa, Air France, and Iberia are the most popular carriers operating from Panama City Tocumen Intl to Rome

What airlines fly to Rome?

Which airport is the most popular layover for flights between Panama City and Rome?

Madrid (MAD) was the most common stop: 57% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Panama City to Rome?

Flights via Paris (CDG) offer the lowest average round-trip price of $830.

Which layover airport has the shortest travel time from Panama City to Rome?

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 00m.

Which layover airport has the shortest connection time from Panama City to Rome?

Madrid (MAD) has the shortest average layover time for this route: 1h 53m.

When to book flights from Panama City to Rome

Cheap Panama City to Rome (PTY to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Rome

Direct flights

How far is Panama City Tocumen Intl to Rome by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Rome?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Rome?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Rome?

What documentation or ID do you need to fly to Rome?

What is the most popular airline from Panama City to Rome?

Best airlines flying from Panama City to Rome

Compare and see reviews for airlines that fly from Panama City to Rome with momondo

Traveling to a place near Rome?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Rome?

Can I find flights from Panama City to Rome with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Rome?

I’m not ready to book a flight from Panama City to Rome right now. Can momondo alert me if prices change?

An easier way to manage your Rome trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome