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Cheap flights from Panama City, Florida to Sioux Falls from $142

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Sioux Falls departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Sioux Falls

Cheap round-trip flights

Delta Logo
4:49 pm - 11:06 pmECP-FSD
6h 17m1 stop
Delta Logo
5:27 am - 10:34 amFSD-ECP
5h 07m1 stop
$274Delta
Find Deal
Fri, Aug 22 - Mon, Aug 25
Delta Logo
4:49 pm - 11:06 pmECP-FSD
6h 17m1 stop
Delta Logo
5:00 am - 1:08 pmFSD-ECP
8h 08m2 stops
$279Delta
Find Deal
Fri, Aug 22 - Sun, Aug 31
American Airlines Logo
10:18 am - 9:03 pmECP-FSD
10h 45m2 stops
American Airlines Logo
7:01 am - 5:30 pmFSD-ECP
10h 29m2 stops
$284American Airlines
Find Deal
Fri, Aug 22 - Mon, Aug 25
American Airlines Logo
6:35 am - 12:58 pmECP-FSD
6h 23m1 stop
American Airlines Logo
1:28 pm - 11:41 pmFSD-ECP
10h 13m2 stops
$294American Airlines
Find Deal
Tue, Aug 19 - Sat, Aug 23
Delta Logo
4:49 pm - 11:06 pmECP-FSD
6h 17m1 stop
Delta Logo
5:27 am - 10:34 amFSD-ECP
5h 07m1 stop
$309Delta
Find Deal
Thu, Aug 21 - Mon, Aug 25
Delta Logo
4:49 pm - 11:06 pmECP-FSD
6h 17m1 stop
Delta Logo
12:56 pm - 11:06 pmFSD-ECP
10h 10m2 stops
$314Delta
Find Deal
Thu, Aug 21 - Tue, Aug 26
United Airlines Logo
11:09 am - 11:40 pmECP-FSD
12h 31m2 stops
United Airlines Logo
6:00 am - 4:20 pmFSD-ECP
10h 20m2 stops
$319United Airlines
Find Deal
Wed, Aug 20 - Sun, Aug 24
United Airlines Logo
1:44 pm - 10:12 pmECP-FSD
8h 28m1 stop
United Airlines Logo
8:00 am - 1:03 pmFSD-ECP
5h 03m1 stop
$339United Airlines
Find Deal
Tue, Aug 19 - Sat, Aug 23
United Airlines Logo
1:44 pm - 10:12 pmECP-FSD
8h 28m1 stop
United Airlines Logo
8:00 am - 1:03 pmFSD-ECP
5h 03m1 stop
$354United Airlines
Find Deal
Sat, Aug 23 - Tue, Aug 26
American Airlines Logo
12:06 pm - 9:03 pmECP-FSD
8h 57m2 stops
American Airlines Logo
1:28 pm - 11:41 pmFSD-ECP
10h 13m2 stops
$362American Airlines
Find Deal
Tue, Aug 19 - Sat, Aug 23

United Airlines flights from Panama City, Florida to Sioux Falls

Our best United Airlines deals on Panama City, Florida to Sioux Falls flight tickets
United Airlines
Aug 20
ECP11:09 amPanama City NW Florida Beaches
12h 31m
2 stops
FSD11:40 pmSioux Falls Joe Foss Field
Aug 24
FSD8:00 amSioux Falls Joe Foss Field
5h 03m
1 stop
ECP1:03 pmPanama City NW Florida Beaches
$314
Find similar
United Airlines
Aug 20
ECP11:09 amPanama City NW Florida Beaches
12h 31m
2 stops
FSD11:40 pmSioux Falls Joe Foss Field
Aug 24
FSD6:00 amSioux Falls Joe Foss Field
10h 20m
2 stops
ECP4:20 pmPanama City NW Florida Beaches
$319
Find similar
United Airlines
Aug 19
ECP1:44 pmPanama City NW Florida Beaches
8h 28m
1 stop
FSD10:12 pmSioux Falls Joe Foss Field
Aug 23
FSD8:00 amSioux Falls Joe Foss Field
5h 03m
1 stop
ECP1:03 pmPanama City NW Florida Beaches
$339
Find similar

American Airlines flights from Panama City, Florida to Sioux Falls

Our best American Airlines deals on Panama City, Florida to Sioux Falls flight tickets
American Airlines
Aug 22
ECP10:18 amPanama City NW Florida Beaches
10h 45m
2 stops
FSD9:03 pmSioux Falls Joe Foss Field
Aug 25
FSD7:01 amSioux Falls Joe Foss Field
10h 29m
2 stops
ECP5:30 pmPanama City NW Florida Beaches
$284
Find similar
American Airlines
Aug 19
ECP6:35 amPanama City NW Florida Beaches
6h 23m
1 stop
FSD12:58 pmSioux Falls Joe Foss Field
Aug 23
FSD1:28 pmSioux Falls Joe Foss Field
10h 13m
2 stops
ECP11:41 pmPanama City NW Florida Beaches
$294
Find similar
American Airlines
Aug 19
ECP6:35 amPanama City NW Florida Beaches
6h 23m
1 stop
FSD12:58 pmSioux Falls Joe Foss Field
Aug 27
FSD1:28 pmSioux Falls Joe Foss Field
8h 41m
2 stops
ECP10:09 pmPanama City NW Florida Beaches
$359
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Fri 8/22

4:49 pm-11:06 pm

1 stop6h 17m

Sioux Falls Joe Foss Field

Mon 8/25

5:27 am-10:34 am

1 stop5h 07m

$274

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Fri 8/22

4:49 pm-11:06 pm

1 stop6h 17m

Sioux Falls Joe Foss Field

Sun 8/31

5:00 am-1:08 pm

2 stops8h 08m

$279

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Fri 8/22

10:18 am-9:03 pm

2 stops10h 45m

Sioux Falls Joe Foss Field

Mon 8/25

7:01 am-5:30 pm

2 stops10h 29m

$284

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 8/19

6:35 am-12:58 pm

1 stop6h 23m

Sioux Falls Joe Foss Field

Sat 8/23

1:28 pm-11:41 pm

2 stops10h 13m

$294

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 8/21

4:49 pm-11:06 pm

1 stop6h 17m

Sioux Falls Joe Foss Field

Mon 8/25

5:27 am-10:34 am

1 stop5h 07m

$309

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 8/21

4:49 pm-11:06 pm

1 stop6h 17m

Sioux Falls Joe Foss Field

Tue 8/26

12:56 pm-11:06 pm

2 stops10h 10m

$314

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/20

11:09 am-11:40 pm

2 stops12h 31m

Sioux Falls Joe Foss Field

Sun 8/24

6:00 am-4:20 pm

2 stops10h 20m

$319

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 8/19

1:44 pm-10:12 pm

1 stop8h 28m

Sioux Falls Joe Foss Field

Sat 8/23

8:00 am-1:03 pm

1 stop5h 03m

$339

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 8/23

1:44 pm-10:12 pm

1 stop8h 28m

Sioux Falls Joe Foss Field

Tue 8/26

8:00 am-1:03 pm

1 stop5h 03m

$354

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 8/19

12:06 pm-9:03 pm

2 stops8h 57m

Sioux Falls Joe Foss Field

Sat 8/23

1:28 pm-11:41 pm

2 stops10h 13m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Panama City, Florida to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Sioux Falls?

The cheapest day to depart on your flight to Sioux Falls is on a Thursday when prices can be found for as low as $332. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $517.

When to book flights from Panama City, Florida to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Sioux Falls (ECP to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Sioux Falls

Best Price Found

$142

Fastest flight time

5h 30m

Direct flights

None

Airports in Sioux Falls

1 airport
The best one-way flight to Sioux Falls from Panama City, Florida in the past 72 hours is $142. The best round-trip flight deal from Panama City, Florida to Sioux Falls found on momondo in the last 72 hours is $274.
The fastest flight from Panama City, Florida to Sioux Falls takes 5h 30m
There are no direct flights from Panama City, Florida to Sioux Falls. Popular non-direct route for this connection is Panama City NW Florida Beaches Airport - Sioux Falls Joe Foss Field Airport.
There is 1 airport near Sioux Falls: Sioux Falls Joe Foss Field (FSD)
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  • How far is Panama City NW Florida Beaches to Sioux Falls Joe Foss Field by plane?

    There are 1106.0 mi between Panama City NW Florida Beaches and Sioux Falls Joe Foss Field. Typically, this will take 5h 30m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport.

  • What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

    The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Sioux Falls?

Best airlines flying from Panama City, Florida to Sioux Falls

Compare and see reviews for airlines that fly from Panama City, Florida to Sioux Falls with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Yankton
Marshall
Worthington

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sioux Falls?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Sioux Falls. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Sioux Falls with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Sioux Falls flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Sioux Falls?

momondo helps you find the best flight between Panama City and Sioux Falls by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Sioux Falls right now. Can momondo alert me if prices change?

Price alerts on flights to Sioux Falls from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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