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Cheap flights from Panama City, Florida to Sioux Falls from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Sioux Falls departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City, Florida to Sioux Falls

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 8:24 pm
ECP
-
FSD
13h 54m2 stops
United Airlines Logo
7:30 am - 4:13 pm
FSD
-
ECP
8h 43m2 stops
$469United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
6:30 am - 8:24 pm
ECP
-
FSD
13h 54m2 stops
United Airlines Logo
7:30 am - 12:02 pm
FSD
-
ECP
52h 32m3 stops
$597United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
6:30 am - 8:24 pm
ECP
-
FSD
13h 54m2 stops
United Airlines Logo
7:30 am - 12:02 pm
FSD
-
ECP
52h 32m3 stops
$621United Airlines
Sat, Jan 31 - Tue, Feb 3

United Airlines flights from Panama City, Florida to Sioux Falls

Our best United Airlines deals on Panama City, Florida to Sioux Falls flight tickets
United Airlines
Dec 28
ECP2:10 pmPanama City NW Florida Beaches
7h 46m
1 stop
FSD9:56 pmSioux Falls Joe Foss Field
Jan 4
FSD7:30 amSioux Falls Joe Foss Field
5h 57m
1 stop
ECP1:27 pmPanama City NW Florida Beaches
$466
Find similar
United Airlines
Jan 31
ECP6:30 amPanama City NW Florida Beaches
13h 54m
2 stops
FSD8:24 pmSioux Falls Joe Foss Field
Feb 3
FSD7:30 amSioux Falls Joe Foss Field
8h 43m
2 stops
ECP4:13 pmPanama City NW Florida Beaches
$469
Find similar
United Airlines
Jan 31
ECP6:30 amPanama City NW Florida Beaches
13h 54m
2 stops
FSD8:24 pmSioux Falls Joe Foss Field
Feb 3
FSD7:30 amSioux Falls Joe Foss Field
52h 32m
3 stops
ECP12:02 pmPanama City NW Florida Beaches
$597
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 1/31

6:30 am-8:24 pm

2 stops13h 54m

Sioux Falls Joe Foss Field

Tue 2/3

7:30 am-4:13 pm

2 stops8h 43m

$469

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 1/31

6:30 am-8:24 pm

2 stops13h 54m

Sioux Falls Joe Foss Field

Tue 2/3

7:30 am-12:02 pm

3 stops52h 32m

$597

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 1/31

6:30 am-8:24 pm

2 stops13h 54m

Sioux Falls Joe Foss Field

Tue 2/3

7:30 am-12:02 pm

3 stops52h 32m

$621

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 1/28

6:03 pm-11:51 am

2 stops17h 48m

$269

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 1/28

7:02 am-12:53 pm

1 stop5h 51m

$281

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 1/29

6:09 pm-12:22 pm

2 stops18h 13m

$294

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 1/31

6:30 am-8:24 pm

2 stops13h 54m

$299

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 1/29

3:45 pm-11:10 pm

1 stop7h 25m

$310

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Fri 1/30

4:54 pm-9:50 pm

3 stops28h 56m

$345

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 1/28

6:30 am-8:24 pm

3 stops13h 54m

$523

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Panama City, Florida to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Sioux Falls?

The cheapest day to depart on your flight to Sioux Falls is on a Thursday when prices can be found for as low as $332. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $517.

Can stopping save me money on Panama City, Florida to Sioux Falls flights?

You could potentially save up to 29% on your flight if you consider stops on a Panama City, Florida to Sioux Falls flight.

When to book flights from Panama City, Florida to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Sioux Falls (ECP to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Sioux Falls

Fastest flight time

7h 46m

Direct flights

None
The fastest flight from Panama City, Florida to Sioux Falls takes 7h 46m
There are no direct flights from Panama City, Florida to Sioux Falls. There are no popular flight routes from Panama City, Florida to Sioux Falls.
Search flight deals

  • How far is Panama City NW Florida Beaches to Sioux Falls Joe Foss Field by plane?

    There are 1106.0 mi between Panama City NW Florida Beaches and Sioux Falls Joe Foss Field. Typically, this will take 7h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport.

  • What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

    The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Sioux Falls?

Best airlines flying from Panama City, Florida to Sioux Falls

Compare and see reviews for airlines that fly from Panama City, Florida to Sioux Falls with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.9
8,014 reviews
Search Delta flights

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Yankton
Marshall
Worthington

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sioux Falls?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Sioux Falls. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Sioux Falls with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Sioux Falls flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Sioux Falls?

momondo helps you find the best flight between Panama City and Sioux Falls by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Sioux Falls right now. Can momondo alert me if prices change?

Price alerts on flights to Sioux Falls from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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