Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Panama City, Florida to Sioux Falls from $278

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Sioux Falls departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Panama City, Florida to Sioux Falls

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:25 pm - 9:45 pm
ECP
-
FSD
7h 20m
1 stop
United Airlines Logo
7:30 am - 1:44 pm
FSD
-
ECP
6h 14m
1 stop
$305United Airlines
Sat, Nov 14 - Mon, Nov 16
United Airlines Logo
11:30 am - 9:45 pm
ECP
-
FSD
10h 15m
2 stops
United Airlines Logo
7:30 am - 1:44 pm
FSD
-
ECP
6h 14m
1 stop
$310United Airlines
Sat, Nov 14 - Mon, Nov 16
Delta Logo
6:00 am - 3:50 pm
ECP
-
FSD
9h 50m
2 stops
Delta Logo
1:00 pm - 10:47 pm
FSD
-
ECP
9h 47m
2 stops
$340Delta
Sat, Nov 14 - Mon, Nov 16
Delta Logo
1:53 pm - 7:59 pm
ECP
-
FSD
6h 06m
1 stop
Delta Logo
5:30 am - 12:39 pm
FSD
-
ECP
7h 09m
1 stop
$465Delta
Wed, Sep 2 - Wed, Sep 9
United Airlines Logo
10:25 am - 5:34 pm
ECP
-
FSD
7h 09m
1 stop
United Airlines Logo
7:40 am - 4:17 pm
FSD
-
ECP
8h 37m
2 stops
$559United Airlines
Sat, Dec 12 - Tue, Dec 15
United Airlines Logo
10:25 am - 5:34 pm
ECP
-
FSD
7h 09m
1 stop
United Airlines Logo
7:40 am - 9:37 am
FSD
-
ECP
25h 57m
1 stop
$568United Airlines
Sat, Dec 12 - Tue, Dec 15
United Airlines Logo
10:25 am - 5:34 pm
ECP
-
FSD
7h 09m
1 stop
United Airlines Logo
7:40 am - 8:06 pm
FSD
-
ECP
12h 26m
2 stops
$575United Airlines
Sat, Dec 12 - Tue, Dec 15
Delta Logo
1:53 pm - 7:59 pm
ECP
-
FSD
6h 06m
1 stop
Delta Logo
1:05 pm - 11:05 pm
FSD
-
ECP
10h 00m
2 stops
$582Delta
Wed, Sep 2 - Wed, Sep 9
United Airlines Logo
10:25 am - 5:34 pm
ECP
-
FSD
7h 09m
1 stop
United Airlines Logo
7:40 am - 4:17 pm
FSD
-
ECP
8h 37m
2 stops
$614United Airlines
Sat, Dec 12 - Tue, Dec 15
United Airlines Logo
10:25 am - 5:34 pm
ECP
-
FSD
7h 09m
1 stop
United Airlines Logo
7:40 am - 9:37 am
FSD
-
ECP
25h 57m
1 stop
$632United Airlines
Sat, Dec 12 - Tue, Dec 15

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Panama City, Florida to Sioux Falls

Our best American Airlines deals on Panama City, Florida to Sioux Falls flight tickets
American Airlines
Oct 4
ECP3:17 pmPanama City NW Florida Beaches
6h 40m
1 stop
FSD9:57 pmSioux Falls Joe Foss Field
Oct 9
FSD12:53 pmSioux Falls Joe Foss Field
8h 06m
1 stop
ECP8:59 pmPanama City NW Florida Beaches
$914
American Airlines
Oct 4
ECP3:17 pmPanama City NW Florida Beaches
6h 40m
1 stop
FSD9:57 pmSioux Falls Joe Foss Field
Oct 9
FSD2:48 pmSioux Falls Joe Foss Field
9h 05m
2 stops
ECP11:53 pmPanama City NW Florida Beaches
$919
American Airlines
Jul 29
ECP7:05 amPanama City NW Florida Beaches
9h 49m
2 stops
FSD4:54 pmSioux Falls Joe Foss Field
Jul 31
FSD7:06 amSioux Falls Joe Foss Field
7h 57m
1 stop
ECP3:03 pmPanama City NW Florida Beaches
$1,001

Delta flights from Panama City, Florida to Sioux Falls

Our best Delta deals on Panama City, Florida to Sioux Falls flight tickets
Delta
Nov 14
ECP6:00 amPanama City NW Florida Beaches
9h 50m
2 stops
FSD3:50 pmSioux Falls Joe Foss Field
Nov 16
FSD1:00 pmSioux Falls Joe Foss Field
9h 47m
2 stops
ECP10:47 pmPanama City NW Florida Beaches
$340
Delta
Sep 2
ECP1:53 pmPanama City NW Florida Beaches
6h 06m
1 stop
FSD7:59 pmSioux Falls Joe Foss Field
Sep 9
FSD5:30 amSioux Falls Joe Foss Field
7h 09m
1 stop
ECP12:39 pmPanama City NW Florida Beaches
$465
Delta
Sep 2
ECP1:53 pmPanama City NW Florida Beaches
6h 06m
1 stop
FSD7:59 pmSioux Falls Joe Foss Field
Sep 9
FSD1:05 pmSioux Falls Joe Foss Field
10h 00m
2 stops
ECP11:05 pmPanama City NW Florida Beaches
$582

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 11/14

2:25 pm-9:45 pm

1 stop7h 20m

Sioux Falls Joe Foss Field

Mon 11/16

7:30 am-1:44 pm

1 stop6h 14m

$305

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 11/14

11:30 am-9:45 pm

2 stops10h 15m

Sioux Falls Joe Foss Field

Mon 11/16

7:30 am-1:44 pm

1 stop6h 14m

$310

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 11/14

6:00 am-3:50 pm

2 stops9h 50m

Sioux Falls Joe Foss Field

Mon 11/16

1:00 pm-10:47 pm

2 stops9h 47m

$340
Quickest round-trip

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 9/2

1:53 pm-7:59 pm

1 stop6h 06m

Sioux Falls Joe Foss Field

Wed 9/9

5:30 am-12:39 pm

1 stop7h 09m

$465

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 12/12

10:25 am-5:34 pm

1 stop7h 09m

Sioux Falls Joe Foss Field

Tue 12/15

7:40 am-4:17 pm

2 stops8h 37m

$559

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 12/12

10:25 am-5:34 pm

1 stop7h 09m

Sioux Falls Joe Foss Field

Tue 12/15

7:40 am-9:37 am

1 stop25h 57m

$568

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 12/12

10:25 am-5:34 pm

1 stop7h 09m

Sioux Falls Joe Foss Field

Tue 12/15

7:40 am-8:06 pm

2 stops12h 26m

$575

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 9/2

1:53 pm-7:59 pm

1 stop6h 06m

Sioux Falls Joe Foss Field

Wed 9/9

1:05 pm-11:05 pm

2 stops10h 00m

$582

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 12/12

10:25 am-5:34 pm

1 stop7h 09m

Sioux Falls Joe Foss Field

Tue 12/15

7:40 am-4:17 pm

2 stops8h 37m

$614

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 12/12

10:25 am-5:34 pm

1 stop7h 09m

Sioux Falls Joe Foss Field

Tue 12/15

7:40 am-9:37 am

1 stop25h 57m

$632

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Panama City, Florida to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama City, Florida to Sioux Falls flights?

You could potentially save up to 16% on your flight if you consider stops on a Panama City, Florida to Sioux Falls flight.

When to book flights from Panama City, Florida to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Sioux Falls (ECP to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Sioux Falls

Fastest flight time

6h 06m

Direct flights

None
The fastest flight from Panama City, Florida to Sioux Falls takes 6h 06m
There are no direct flights from Panama City, Florida to Sioux Falls. There are no popular flight routes from Panama City, Florida to Sioux Falls.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to Sioux Falls

  • How far is Panama City NW Florida Beaches to Sioux Falls Joe Foss Field by plane?

    There are 1106.0 mi between Panama City NW Florida Beaches and Sioux Falls Joe Foss Field. Typically, this will take 6h 06m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport.

  • What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

    The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Yankton
Marshall
Worthington

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sioux Falls?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Sioux Falls. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Sioux Falls with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Sioux Falls flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Sioux Falls?

momondo helps you find the best flight between Panama City and Sioux Falls by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Sioux Falls right now. Can momondo alert me if prices change?

Price alerts on flights to Sioux Falls from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Sioux Falls trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/11
Tue 8/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States