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Cheap flights from Panama City, Florida to Sioux Falls from $354

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Sioux Falls departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Sioux Falls

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:10 pm - 11:40 pm
ECP
-
FSD
6h 30m
1 stop
Delta Logo
5:25 am - 10:15 am
FSD
-
ECP
4h 50m
1 stop
$354Delta
Tue, Apr 14 - Tue, Apr 28
Delta Logo
5:10 pm - 11:40 pm
ECP
-
FSD
6h 30m
1 stop
Delta Logo
1:44 pm - 11:12 pm
FSD
-
ECP
9h 28m
2 stops
$359Delta
Tue, Apr 14 - Tue, Apr 28
United Airlines Logo
6:30 am - 4:16 pm
ECP
-
FSD
9h 46m
2 stops
United Airlines Logo
11:15 am - 9:59 pm
FSD
-
ECP
10h 44m
2 stops
$364United Airlines
Tue, Apr 14 - Tue, Apr 28
American Airlines Logo
10:48 am - 7:09 pm
ECP
-
FSD
8h 21m
2 stops
American Airlines Logo
1:41 pm - 9:54 pm
FSD
-
ECP
8h 13m
1 stop
$369American Airlines
Sat, May 2 - Thu, May 7
United Airlines Logo
1:39 pm - 9:52 pm
ECP
-
FSD
8h 13m
1 stop
United Airlines Logo
7:40 am - 12:58 pm
FSD
-
ECP
5h 18m
1 stop
$381United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
1:39 pm - 9:52 pm
ECP
-
FSD
8h 13m
1 stop
United Airlines Logo
6:00 am - 4:23 pm
FSD
-
ECP
10h 23m
2 stops
$386United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
11:38 am - 9:52 pm
ECP
-
FSD
10h 14m
2 stops
United Airlines Logo
6:00 am - 4:23 pm
FSD
-
ECP
10h 23m
2 stops
$391United Airlines
Wed, Aug 26 - Sat, Aug 29
American Airlines Logo
7:00 am - 12:56 pm
ECP
-
FSD
5h 56m
1 stop
American Airlines Logo
1:41 pm - 9:54 pm
FSD
-
ECP
8h 13m
1 stop
$412American Airlines
Sat, May 2 - Thu, May 7
United Airlines Logo
1:39 pm - 9:52 pm
ECP
-
FSD
8h 13m
1 stop
United Airlines Logo
6:00 am - 4:23 pm
FSD
-
ECP
10h 23m
2 stops
$421United Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
11:38 am - 9:52 pm
ECP
-
FSD
10h 14m
2 stops
United Airlines Logo
6:00 am - 4:23 pm
FSD
-
ECP
10h 23m
2 stops
$456United Airlines
Wed, Aug 26 - Sat, Aug 29

United Airlines flights from Panama City, Florida to Sioux Falls

Our best United Airlines deals on Panama City, Florida to Sioux Falls flight tickets
United Airlines
Apr 14
ECP6:30 amPanama City NW Florida Beaches
9h 46m
2 stops
FSD4:16 pmSioux Falls Joe Foss Field
Apr 28
FSD11:15 amSioux Falls Joe Foss Field
10h 44m
2 stops
ECP9:59 pmPanama City NW Florida Beaches
$364
United Airlines
Aug 26
ECP1:39 pmPanama City NW Florida Beaches
8h 13m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
Aug 29
FSD7:40 amSioux Falls Joe Foss Field
5h 18m
1 stop
ECP12:58 pmPanama City NW Florida Beaches
$381
United Airlines
Aug 26
ECP1:39 pmPanama City NW Florida Beaches
8h 13m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
Aug 29
FSD6:00 amSioux Falls Joe Foss Field
10h 23m
2 stops
ECP4:23 pmPanama City NW Florida Beaches
$386

American Airlines flights from Panama City, Florida to Sioux Falls

Our best American Airlines deals on Panama City, Florida to Sioux Falls flight tickets
American Airlines
May 2
ECP10:48 amPanama City NW Florida Beaches
8h 21m
2 stops
FSD7:09 pmSioux Falls Joe Foss Field
May 7
FSD1:41 pmSioux Falls Joe Foss Field
8h 13m
1 stop
ECP9:54 pmPanama City NW Florida Beaches
$369
American Airlines
May 2
ECP7:00 amPanama City NW Florida Beaches
5h 56m
1 stop
FSD12:56 pmSioux Falls Joe Foss Field
May 7
FSD1:41 pmSioux Falls Joe Foss Field
8h 13m
1 stop
ECP9:54 pmPanama City NW Florida Beaches
$412

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 4/14

5:10 pm-11:40 pm

1 stop6h 30m

Sioux Falls Joe Foss Field

Tue 4/28

5:25 am-10:15 am

1 stop4h 50m

$354

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 4/14

5:10 pm-11:40 pm

1 stop6h 30m

Sioux Falls Joe Foss Field

Tue 4/28

1:44 pm-11:12 pm

2 stops9h 28m

$359

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 4/14

6:30 am-4:16 pm

2 stops9h 46m

Sioux Falls Joe Foss Field

Tue 4/28

11:15 am-9:59 pm

2 stops10h 44m

$364

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 5/2

10:48 am-7:09 pm

2 stops8h 21m

Sioux Falls Joe Foss Field

Thu 5/7

1:41 pm-9:54 pm

1 stop8h 13m

$369

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/26

1:39 pm-9:52 pm

1 stop8h 13m

Sioux Falls Joe Foss Field

Sat 8/29

7:40 am-12:58 pm

1 stop5h 18m

$381

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/26

1:39 pm-9:52 pm

1 stop8h 13m

Sioux Falls Joe Foss Field

Sat 8/29

6:00 am-4:23 pm

2 stops10h 23m

$386

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/26

11:38 am-9:52 pm

2 stops10h 14m

Sioux Falls Joe Foss Field

Sat 8/29

6:00 am-4:23 pm

2 stops10h 23m

$391

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sat 5/2

7:00 am-12:56 pm

1 stop5h 56m

Sioux Falls Joe Foss Field

Thu 5/7

1:41 pm-9:54 pm

1 stop8h 13m

$412

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/26

1:39 pm-9:52 pm

1 stop8h 13m

Sioux Falls Joe Foss Field

Sat 8/29

6:00 am-4:23 pm

2 stops10h 23m

$421

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Wed 8/26

11:38 am-9:52 pm

2 stops10h 14m

Sioux Falls Joe Foss Field

Sat 8/29

6:00 am-4:23 pm

2 stops10h 23m

$456

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Panama City, Florida to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama City, Florida to Sioux Falls flights?

You could potentially save up to 11% on your flight if you consider stops on a Panama City, Florida to Sioux Falls flight.

When to book flights from Panama City, Florida to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Sioux Falls (ECP to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Sioux Falls

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from Panama City, Florida to Sioux Falls takes 6h 30m
There are no direct flights from Panama City, Florida to Sioux Falls. There are no popular flight routes from Panama City, Florida to Sioux Falls.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to Sioux Falls

  • How far is Panama City NW Florida Beaches to Sioux Falls Joe Foss Field by plane?

    There are 1106.0 mi between Panama City NW Florida Beaches and Sioux Falls Joe Foss Field. Typically, this will take 6h 30m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport were last updated today.

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport.

  • What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

    The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Yankton
Marshall
Worthington

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sioux Falls?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Sioux Falls. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Sioux Falls with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Sioux Falls flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Sioux Falls?

momondo helps you find the best flight between Panama City and Sioux Falls by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Sioux Falls right now. Can momondo alert me if prices change?

Price alerts on flights to Sioux Falls from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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