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Cheap flights from Panama City, Florida to Sioux Falls from $259

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Sioux Falls departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Sioux Falls

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:00 pm - 11:09 pmECP-FSD
6h 09m1 stop
Delta Logo
5:05 am - 10:26 amFSD-ECP
5h 21m1 stop
$259Delta
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
5:00 pm - 11:09 pmECP-FSD
6h 09m1 stop
Delta Logo
1:30 pm - 10:37 pmFSD-ECP
9h 07m2 stops
$264Delta
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
5:00 pm - 11:09 pmECP-FSD
6h 09m1 stop
Delta Logo
5:05 am - 10:26 amFSD-ECP
5h 21m1 stop
$274Delta
Find Deal
Tue, Nov 11 - Tue, Nov 18
American Airlines Logo
3:22 pm - 9:09 pmECP-FSD
5h 47m1 stop
American Airlines Logo
6:30 am - 12:28 pmFSD-ECP
5h 58m1 stop
$329American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
3:22 pm - 9:09 pmECP-FSD
5h 47m1 stop
American Airlines Logo
6:30 am - 12:28 pmFSD-ECP
5h 58m1 stop
$344American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
United Airlines Logo
2:15 pm - 9:47 pmECP-FSD
7h 32m1 stop
United Airlines Logo
9:14 am - 8:06 pmFSD-ECP
10h 52m2 stops
$384United Airlines
Find Deal
Thu, Apr 16 - Mon, Apr 20
American Airlines Logo
11:04 am - 11:59 pmECP-FSD
12h 55m2 stops
American Airlines Logo
7:16 pm - 11:29 amFSD-ECP
16h 13m2 stops
$398American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
2:37 pm - 11:59 pmECP-FSD
9h 22m2 stops
American Airlines Logo
6:30 am - 12:28 pmFSD-ECP
5h 58m1 stop
$404American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
United Airlines Logo
2:15 pm - 9:47 pmECP-FSD
7h 32m1 stop
United Airlines Logo
5:00 pm - 1:09 pmFSD-ECP
20h 09m3 stops
$524United Airlines
Find Deal
Thu, Apr 16 - Mon, Apr 20
United Airlines Logo
2:15 pm - 9:47 pmECP-FSD
7h 32m1 stop
United Airlines Logo
5:00 pm - 1:09 pmFSD-ECP
20h 09m3 stops
$529United Airlines
Find Deal
Thu, Apr 16 - Mon, Apr 20

Delta flights from Panama City, Florida to Sioux Falls

Our best Delta deals on Panama City, Florida to Sioux Falls flight tickets
Delta
Nov 11
ECP5:00 pmPanama City NW Florida Beaches
6h 09m
1 stop
FSD11:09 pmSioux Falls Joe Foss Field
Nov 18
FSD5:05 amSioux Falls Joe Foss Field
5h 21m
1 stop
ECP10:26 amPanama City NW Florida Beaches
$259
Find similar
Delta
Nov 11
ECP5:00 pmPanama City NW Florida Beaches
6h 09m
1 stop
FSD11:09 pmSioux Falls Joe Foss Field
Nov 18
FSD1:30 pmSioux Falls Joe Foss Field
9h 07m
2 stops
ECP10:37 pmPanama City NW Florida Beaches
$264
Find similar
Delta
Nov 11
ECP5:00 pmPanama City NW Florida Beaches
6h 09m
1 stop
FSD11:09 pmSioux Falls Joe Foss Field
Nov 18
FSD5:05 amSioux Falls Joe Foss Field
5h 21m
1 stop
ECP10:26 amPanama City NW Florida Beaches
$274
Find similar

United Airlines flights from Panama City, Florida to Sioux Falls

Our best United Airlines deals on Panama City, Florida to Sioux Falls flight tickets
United Airlines
Oct 28
ECP3:00 pmPanama City NW Florida Beaches
8h 44m
2 stops
FSD11:44 pmSioux Falls Joe Foss Field
Nov 1
FSD8:00 amSioux Falls Joe Foss Field
8h 24m
2 stops
ECP4:24 pmPanama City NW Florida Beaches
$369
Find similar
United Airlines
Apr 16
ECP2:15 pmPanama City NW Florida Beaches
7h 32m
1 stop
FSD9:47 pmSioux Falls Joe Foss Field
Apr 20
FSD9:14 amSioux Falls Joe Foss Field
10h 52m
2 stops
ECP8:06 pmPanama City NW Florida Beaches
$384
Find similar
United Airlines
Apr 16
ECP2:15 pmPanama City NW Florida Beaches
7h 32m
1 stop
FSD9:47 pmSioux Falls Joe Foss Field
Apr 20
FSD5:00 pmSioux Falls Joe Foss Field
20h 09m
3 stops
ECP1:09 pmPanama City NW Florida Beaches
$524
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 11/11

5:00 pm-11:09 pm

1 stop6h 09m

Sioux Falls Joe Foss Field

Tue 11/18

5:05 am-10:26 am

1 stop5h 21m

$259

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 11/11

5:00 pm-11:09 pm

1 stop6h 09m

Sioux Falls Joe Foss Field

Tue 11/18

1:30 pm-10:37 pm

2 stops9h 07m

$264

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 11/11

5:00 pm-11:09 pm

1 stop6h 09m

Sioux Falls Joe Foss Field

Tue 11/18

5:05 am-10:26 am

1 stop5h 21m

$274

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 11/13

3:22 pm-9:09 pm

1 stop5h 47m

Sioux Falls Joe Foss Field

Sun 11/16

6:30 am-12:28 pm

1 stop5h 58m

$329

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 11/13

3:22 pm-9:09 pm

1 stop5h 47m

Sioux Falls Joe Foss Field

Sun 11/16

6:30 am-12:28 pm

1 stop5h 58m

$344

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 4/16

2:15 pm-9:47 pm

1 stop7h 32m

Sioux Falls Joe Foss Field

Mon 4/20

9:14 am-8:06 pm

2 stops10h 52m

$384

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 11/13

11:04 am-11:59 pm

2 stops12h 55m

Sioux Falls Joe Foss Field

Sun 11/16

7:16 pm-11:29 am

2 stops16h 13m

$398

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 11/13

2:37 pm-11:59 pm

2 stops9h 22m

Sioux Falls Joe Foss Field

Sun 11/16

6:30 am-12:28 pm

1 stop5h 58m

$404

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 4/16

2:15 pm-9:47 pm

1 stop7h 32m

Sioux Falls Joe Foss Field

Mon 4/20

5:00 pm-1:09 pm

3 stops20h 09m

$524

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Thu 4/16

2:15 pm-9:47 pm

1 stop7h 32m

Sioux Falls Joe Foss Field

Mon 4/20

5:00 pm-1:09 pm

3 stops20h 09m

$529

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Panama City, Florida to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Sioux Falls?

The cheapest day to depart on your flight to Sioux Falls is on a Thursday when prices can be found for as low as $332. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $517.

Can stopping save me money on Panama City, Florida to Sioux Falls flights?

You could potentially save up to 6% on your flight if you consider stops on a Panama City, Florida to Sioux Falls flight.

When to book flights from Panama City, Florida to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Sioux Falls (ECP to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Sioux Falls

Direct flights

None
There are no direct flights from Panama City, Florida to Sioux Falls. There are no popular flight routes from Panama City, Florida to Sioux Falls.
Search flight deals

  • How far is Panama City NW Florida Beaches to Sioux Falls Joe Foss Field by plane?

    There are 1106.0 mi between Panama City NW Florida Beaches and Sioux Falls Joe Foss Field. Typically, this will take 5h 42m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Sioux Falls Joe Foss Field Airport.

  • What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

    The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Sioux Falls?

Best airlines flying from Panama City, Florida to Sioux Falls

Compare and see reviews for airlines that fly from Panama City, Florida to Sioux Falls with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.9
7,982 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Yankton
Marshall
Worthington

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sioux Falls?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Sioux Falls. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Sioux Falls with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Sioux Falls flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Sioux Falls?

momondo helps you find the best flight between Panama City and Sioux Falls by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Sioux Falls right now. Can momondo alert me if prices change?

Price alerts on flights to Sioux Falls from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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