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Cheap flights from Panama City, Florida to Chicago from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Chicago departing on 12/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:32 pm - 6:43 pmECP-ORD
5h 11m1 stop
Delta Logo
5:30 am - 10:17 amORD-ECP
4h 47m1 stop
$229Delta
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Thu, Dec 18 - Mon, Dec 22
Delta Logo
4:26 pm - 9:56 pmECP-ORD
5h 30m1 stop
Delta Logo
6:45 am - 12:47 pmORD-ECP
6h 02m1 stop
$249Delta
Find Deal
Mon, Dec 8 - Sun, Dec 14
United Airlines Logo
2:10 pm - 4:54 pmECP-ORD
2h 44mnonstop
United Airlines Logo
10:45 am - 1:27 pmORD-ECP
2h 42mnonstop
$250United Airlines
Find Deal
Sat, Dec 20 - Thu, Jan 1
Delta Logo
12:59 pm - 8:47 pmECP-ORD
7h 48m1 stop
Delta Logo
5:59 pm - 10:53 pmORD-ECP
4h 54m1 stop
$254Delta
Find Deal
Wed, Jan 14 - Sun, Jan 18
American Airlines Logo
7:02 am - 1:55 pmECP-ORD
6h 53m1 stop
American Airlines Logo
9:58 am - 12:30 pmORD-ECP
2h 32mnonstop
$259American Airlines
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Thu, Jan 29 - Sun, Feb 15
Southwest Logo
7:15 am - 12:15 pmECP-ORD
5h 00m1 stop
Southwest Logo
6:05 am - 6:10 pmORD-ECP
12h 05m2 stops
$260Southwest
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Thu, Dec 11 - Wed, Jan 7
United Airlines Logo
2:10 pm - 4:54 pmECP-ORD
2h 44mnonstop
United Airlines Logo
10:45 am - 1:27 pmORD-ECP
2h 42mnonstop
$264United Airlines
Find Deal
Sat, Dec 20 - Thu, Jan 1
Delta Logo
5:00 pm - 10:43 pmECP-ORD
5h 43m1 stop
Delta Logo
6:45 am - 12:47 pmORD-ECP
6h 02m1 stop
$269Delta
Find Deal
Wed, Dec 3 - Sun, Dec 7
Delta Logo
12:15 pm - 4:56 pmECP-ORD
4h 41m1 stop
Delta Logo
6:30 am - 6:53 pmORD-ECP
12h 23m2 stops
$271Delta
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Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
1:34 pm - 7:29 pmECP-ORD
5h 55m1 stop
American Airlines Logo
9:54 am - 5:33 pmORD-ECP
7h 39m2 stops
$274American Airlines
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Wed, Jan 14 - Sun, Jan 18

United Airlines flights from Panama City, Florida to Chicago O'Hare Intl Airport

Our best United Airlines deals on Panama City, Florida to Chicago O'Hare Intl Airport flight tickets
United Airlines
Dec 20
ECP2:10 pmPanama City NW Florida Beaches
2h 44m
ORD4:54 pmChicago O'Hare Intl
Jan 1
ORD10:45 amChicago O'Hare Intl
2h 42m
ECP1:27 pmPanama City NW Florida Beaches
$250
Find similar
United Airlines
Dec 20
ECP2:10 pmPanama City NW Florida Beaches
2h 44m
ORD4:54 pmChicago O'Hare Intl
Jan 1
ORD10:45 amChicago O'Hare Intl
2h 42m
ECP1:27 pmPanama City NW Florida Beaches
$264
Find similar
United Airlines
Dec 20
ECP2:10 pmPanama City NW Florida Beaches
2h 44m
ORD4:54 pmChicago O'Hare Intl
Jan 1
ORD4:00 pmChicago O'Hare Intl
5h 54m
1 stop
ECP9:54 pmPanama City NW Florida Beaches
$341
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American Airlines flights from Panama City, Florida to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama City, Florida to Chicago O'Hare Intl Airport flight tickets
American Airlines
Jan 29
ECP7:02 amPanama City NW Florida Beaches
6h 53m
1 stop
ORD1:55 pmChicago O'Hare Intl
Feb 15
ORD9:58 amChicago O'Hare Intl
2h 32m
ECP12:30 pmPanama City NW Florida Beaches
$259
Find similar
American Airlines
Jan 14
ECP1:34 pmPanama City NW Florida Beaches
5h 55m
1 stop
ORD7:29 pmChicago O'Hare Intl
Jan 18
ORD9:54 amChicago O'Hare Intl
7h 39m
2 stops
ECP5:33 pmPanama City NW Florida Beaches
$274
Find similar
American Airlines
Jan 14
ECP12:03 pmPanama City NW Florida Beaches
8h 50m
2 stops
ORD8:53 pmChicago O'Hare Intl
Jan 18
ORD8:00 amChicago O'Hare Intl
9h 33m
2 stops
ECP5:33 pmPanama City NW Florida Beaches
$279
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 12/18

1:32 pm-6:43 pm

1 stop5h 11m

Chicago O'Hare Intl

Mon 12/22

5:30 am-10:17 am

1 stop4h 47m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Mon 12/8

4:26 pm-9:56 pm

1 stop5h 30m

Chicago O'Hare Intl

Sun 12/14

6:45 am-12:47 pm

1 stop6h 02m

$249

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 12/20

2:10 pm-4:54 pm

Nonstop2h 44m

Chicago O'Hare Intl

Thu 1/1

10:45 am-1:27 pm

Nonstop2h 42m

$250

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 1/14

12:59 pm-8:47 pm

1 stop7h 48m

Chicago O'Hare Intl

Sun 1/18

5:59 pm-10:53 pm

1 stop4h 54m

$254

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 1/29

7:02 am-1:55 pm

1 stop6h 53m

Chicago O'Hare Intl

Sun 2/15

9:58 am-12:30 pm

Nonstop2h 32m

$259

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 12/11

7:15 am-12:15 pm

1 stop5h 00m

Chicago O'Hare Intl

Wed 1/7

6:05 am-6:10 pm

2 stops12h 05m

$260

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 12/20

2:10 pm-4:54 pm

Nonstop2h 44m

Chicago O'Hare Intl

Thu 1/1

10:45 am-1:27 pm

Nonstop2h 42m

$264

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 12/3

5:00 pm-10:43 pm

1 stop5h 43m

Chicago O'Hare Intl

Sun 12/7

6:45 am-12:47 pm

1 stop6h 02m

$269

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 2/14

12:15 pm-4:56 pm

1 stop4h 41m

Chicago O'Hare Intl

Wed 2/18

6:30 am-6:53 pm

2 stops12h 23m

$271

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 1/14

1:34 pm-7:29 pm

1 stop5h 55m

Chicago O'Hare Intl

Sun 1/18

9:54 am-5:33 pm

2 stops7h 39m

$274

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City, Florida to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of May is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama City, Florida averaging around $279.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $401. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $996.

What is the cheapest Panama City NW Florida Beaches to Chicago O'Hare Intl flight route?

Fly from Panama City NW Florida Beaches to Chicago O'Hare Intl for the best Panama City NW Florida Beaches - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama City, Florida when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $344 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama City, Florida for as low as $257 on momondo.

What cabin class options are available on Panama City NW Florida Beaches to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Panama City NW Florida Beaches to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Chicago O'Hare Intl Airport.

How have Panama City, Florida to Chicago O'Hare Intl Airport flight prices changed over time?

As of November 2025, prices for Panama City, Florida to Chicago O'Hare Intl Airport flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from Panama City, Florida to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Chicago O'Hare Intl Airport (ECP to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Chicago O'Hare Intl Airport

Best Price Found

$220

Fastest flight time

2h 31m

Direct flights

Mon, Tue, Wed, Fri and Sun
The best one-way flight to Chicago O'Hare Intl Airport from Panama City, Florida in the past 72 hours is $220. The best round-trip flight deal from Panama City, Florida to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $226.
The fastest flight from Panama City, Florida to Chicago O'Hare Intl Airport takes 2h 31m
Direct flights go from Panama City, Florida to Chicago O'Hare Intl Airport on Monday, Tuesday, Wednesday, Friday and Sunday. The only airline offering direct flights is United Airlines.
Search flight deals

  • How far is Panama City NW Florida Beaches to Chicago O'Hare Intl by plane?

    Panama City NW Florida Beaches and Chicago O'Hare Intl are 825.6 mi apart from one another. By plane, this route typically takes 2h 40m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Chicago O'Hare Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City, Florida to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Panama City, Florida to Chicago O'Hare Intl Airport?

Best airlines flying from Panama City, Florida to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama City, Florida to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,002 reviews
Search Delta flights
United AirlinesPriceFrom $219Free CancellationRating
7.4
9,028 reviews
Search United Airlines flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,251 reviews
Search Southwest flights
American AirlinesPriceFrom $228Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Tinley Park
Janesville
Aurora
Elgin
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Chicago for you.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Chicago?

Once all potential Panama City to Chicago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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