Cheap flights from Panama City, Florida to Central America from $234

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Central America departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City, Florida to Central America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 2:14 pm
ECP
-
PTY
7h 44m
1 stop
United Airlines Logo
7:55 am - 8:01 pm
PTY
-
ECP
12h 06m
1 stop
$547United Airlines
Tue, Jun 23 - Tue, Jun 30
Southwest Logo
9:10 am - 6:40 pm
ECP
-
SJO
10h 30m
2 stops
Southwest Logo
9:00 am - 8:10 pm
SJO
-
ECP
10h 10m
2 stops
$586Southwest
Wed, Sep 23 - Sun, Sep 27
United Airlines Logo
6:15 am - 4:12 pm
ECP
-
PTY
9h 57m
1 stop
United Airlines Logo
3:30 pm - 8:01 pm
PTY
-
ECP
28h 31m
1 stop
$596United Airlines
Mon, May 25 - Wed, Jun 10
United Airlines Logo
6:30 am - 6:37 pm
ECP
-
PTY
12h 07m
1 stop
United Airlines Logo
7:55 am - 4:23 pm
PTY
-
ECP
8h 28m
1 stop
$597United Airlines
Thu, Jun 4 - Sun, Jun 7
United Airlines Logo
5:05 pm - 4:12 pm
ECP
-
PTY
23h 07m
1 stop
United Airlines Logo
3:30 pm - 1:51 pm
PTY
-
ECP
22h 21m
1 stop
$605United Airlines
Sun, May 24 - Tue, Jun 9
United Airlines Logo
11:40 am - 6:37 pm
ECP
-
PTY
6h 57m
1 stop
United Airlines Logo
7:55 am - 9:58 pm
PTY
-
ECP
14h 03m
1 stop
$617United Airlines
Thu, May 28 - Fri, Jun 12
Delta Logo
4:54 pm - 12:50 pm
ECP
-
PTY
19h 56m
1 stop
Delta Logo
2:24 pm - 11:44 pm
PTY
-
ECP
9h 20m
1 stop
$624Delta
Fri, May 29 - Wed, Jun 10
Delta Logo
6:00 am - 12:50 pm
ECP
-
PTY
6h 50m
1 stop
Delta Logo
2:24 pm - 11:44 pm
PTY
-
ECP
9h 20m
1 stop
$631Delta
Sat, May 30 - Mon, Jun 8
American Airlines Logo
2:35 pm - 11:05 am
ECP
-
SJO
21h 30m
2 stops
American Airlines Logo
2:45 pm - 2:25 pm
SJO
-
ECP
22h 40m
2 stops
$638American Airlines
Fri, Oct 9 - Fri, Oct 16
American Airlines Logo
7:30 am - 1:58 pm
ECP
-
SJO
7h 28m
1 stop
American Airlines Logo
2:45 pm - 12:50 pm
SJO
-
ECP
21h 05m
2 stops
$655American Airlines
Fri, Oct 9 - Fri, Oct 16

Southwest flights from Panama City, Florida to Central America

Our best Southwest deals on Panama City, Florida to Central America flight tickets
Southwest
Sep 23
ECP9:10 amPanama City NW Florida Beaches
10h 30m
2 stops
SJO6:40 pmSan José Juan Santamaria Intl
Sep 27
SJO9:00 amSan José Juan Santamaria Intl
10h 10m
2 stops
ECP8:10 pmPanama City NW Florida Beaches
$586
Southwest
May 19
ECP7:55 amPanama City NW Florida Beaches
12h 05m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
May 22
SJO9:00 amSan José Juan Santamaria Intl
11h 40m
2 stops
ECP9:40 pmPanama City NW Florida Beaches
$663
Southwest
May 31
ECP9:45 amPanama City NW Florida Beaches
10h 15m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
Jun 2
SJO9:00 amSan José Juan Santamaria Intl
10h 45m
2 stops
ECP8:45 pmPanama City NW Florida Beaches
$821

American Airlines flights from Panama City, Florida to Central America

Our best American Airlines deals on Panama City, Florida to Central America flight tickets
American Airlines
Oct 9
ECP2:35 pmPanama City NW Florida Beaches
21h 30m
2 stops
SJO11:05 amSan José Juan Santamaria Intl
Oct 16
SJO2:45 pmSan José Juan Santamaria Intl
22h 40m
2 stops
ECP2:25 pmPanama City NW Florida Beaches
$638
American Airlines
Oct 9
ECP7:30 amPanama City NW Florida Beaches
7h 28m
1 stop
SJO1:58 pmSan José Juan Santamaria Intl
Oct 16
SJO2:45 pmSan José Juan Santamaria Intl
21h 05m
2 stops
ECP12:50 pmPanama City NW Florida Beaches
$655
American Airlines
May 19
ECP4:40 pmPanama City NW Florida Beaches
21h 46m
2 stops
SJO1:26 pmSan José Juan Santamaria Intl
May 22
SJO11:59 pmSan José Juan Santamaria Intl
21h 37m
1 stop
ECP10:36 pmPanama City NW Florida Beaches
$689

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Tue 6/23

6:30 am-2:14 pm

1 stop7h 44m

Panama City Tocumen Intl

Tue 6/30

7:55 am-8:01 pm

1 stop12h 06m

$547

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Wed 9/23

9:10 am-6:40 pm

2 stops10h 30m

San José Juan Santamaria Intl

Sun 9/27

9:00 am-8:10 pm

2 stops10h 10m

$586

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Mon 5/25

6:15 am-4:12 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 6/10

3:30 pm-8:01 pm

1 stop28h 31m

$596

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 6/4

6:30 am-6:37 pm

1 stop12h 07m

Panama City Tocumen Intl

Sun 6/7

7:55 am-4:23 pm

1 stop8h 28m

$597

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Sun 5/24

5:05 pm-4:12 pm

1 stop23h 07m

Panama City Tocumen Intl

Tue 6/9

3:30 pm-1:51 pm

1 stop22h 21m

$605

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 5/28

11:40 am-6:37 pm

1 stop6h 57m

Panama City Tocumen Intl

Fri 6/12

7:55 am-9:58 pm

1 stop14h 03m

$617

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Fri 5/29

4:54 pm-12:50 pm

1 stop19h 56m

Panama City Tocumen Intl

Wed 6/10

2:24 pm-11:44 pm

1 stop9h 20m

$624
Quickest round-trip

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Sat 5/30

6:00 am-12:50 pm

1 stop6h 50m

Panama City Tocumen Intl

Mon 6/8

2:24 pm-11:44 pm

1 stop9h 20m

$631

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 10/9

2:35 pm-11:05 am

2 stops21h 30m

San José Juan Santamaria Intl

Fri 10/16

2:45 pm-2:25 pm

2 stops22h 40m

$638

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 10/9

7:30 am-1:58 pm

1 stop7h 28m

San José Juan Santamaria Intl

Fri 10/16

2:45 pm-12:50 pm

2 stops21h 05m

$655

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, April is the cheapest month to fly from Panama City, Florida to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $387. If you don’t want to visit Central America in April, then you should wait until September to fly from Panama City, Florida, when ticket prices are also cheap, with an average price of $395.

Can stopping save me money on Panama City, Florida to Central America flights?

You could potentially save up to 36% on your flight if you consider stops on a Panama City, Florida to Central America flight.

Cheap Panama City, Florida to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Central America

Fastest flight time

6h 40m

Direct flights

None
The fastest flight from Panama City, Florida to Central America takes 6h 40m
There are no direct flights from Panama City, Florida to Central America. There are no popular flight routes from Panama City, Florida to Central America.

Frequently asked questions about flying from Panama City, Florida to Central America

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Central America?

    Prices for flights from Panama City NW Florida Beaches Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Central America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Central America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to Central America

Compare and see reviews for airlines that fly from Panama City, Florida to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $372Free CancellationRating
7.9
8,454 reviews
Search Delta flights
United AirlinesPriceFrom $397Free CancellationRating
7.4
9,694 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Central America?

Finding the right flight to Central America from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Panama City to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Panama City with this policy.

How can momondo help me find flights from Panama City to Central America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Central America from Panama City.

I’m not ready to book a flight from Panama City to Central America right now. Can momondo alert me if prices change?

Price alerts on flights to Central America from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Central America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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1 adult
Tue 6/9
Tue 6/16

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