Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Panama City, Florida to Central America from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Central America departing on 3/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City, Florida to Central America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 6:37 pm
ECP
-
PTY
12h 07m
1 stop
United Airlines Logo
10:00 am - 9:59 pm
PTY
-
ECP
11h 59m
1 stop
$477United Airlines
Sat, Apr 18 - Wed, Apr 22
Delta Logo
7:20 am - 10:15 pm
ECP
-
SJO
14h 55m
1 stop
Delta Logo
7:00 am - 7:50 pm
SJO
-
ECP
12h 50m
1 stop
$515Delta
Mon, Feb 2 - Thu, Feb 5
Multiple Airlines Logo
6:30 am - 6:50 pm
ECP
-
SJO
13h 20m
2 stops
Multiple Airlines Logo
5:05 am - 9:59 pm
SJO
-
ECP
15h 54m
2 stops
$523Multiple Airlines
Mon, Apr 20 - Fri, Apr 24
Southwest Logo
12:20 pm - 7:00 pm
ECP
-
SJO
7h 40m
1 stop
Southwest Logo
9:00 am - 9:40 pm
SJO
-
ECP
11h 40m
2 stops
$524Southwest
Mon, Apr 20 - Fri, Apr 24
United Airlines Logo
6:30 am - 7:37 pm
ECP
-
SJO
14h 07m
1 stop
United Airlines Logo
1:25 pm - 9:59 pm
SJO
-
ECP
7h 34m
1 stop
$526United Airlines
Mon, Apr 20 - Fri, Apr 24
American Airlines Logo
8:20 am - 7:12 pm
ECP
-
SJO
11h 52m
2 stops
American Airlines Logo
6:00 am - 10:17 pm
SJO
-
ECP
15h 17m
2 stops
$531American Airlines
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
12:39 pm - 9:43 pm
ECP
-
SJO
10h 04m
1 stop
American Airlines Logo
2:20 pm - 12:09 pm
SJO
-
ECP
20h 49m
1 stop
$585American Airlines
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
6:41 am - 9:43 pm
ECP
-
SJO
16h 02m
1 stop
American Airlines Logo
12:26 pm - 10:06 am
SJO
-
ECP
20h 40m
2 stops
$617American Airlines
Wed, Mar 18 - Sun, Mar 22
Delta Logo
6:00 am - 12:50 pm
ECP
-
LIR
6h 50m
1 stop
Delta Logo
3:05 pm - 10:39 pm
LIR
-
ECP
7h 34m
1 stop
$622Delta
Sat, Feb 21 - Sat, Feb 28
GOL Logo
7:02 am - 10:30 pm
ECP
-
SJO
15h 28m
2 stops
GOL Logo
6:00 am - 5:33 pm
SJO
-
ECP
11h 33m
2 stops
$697GOL
Fri, Jan 30 - Wed, Feb 4

Southwest flights from Panama City, Florida to Central America

Our best Southwest deals on Panama City, Florida to Central America flight tickets
Southwest
Apr 20
ECP12:20 pmPanama City NW Florida Beaches
7h 40m
1 stop
SJO7:00 pmSan José Juan Santamaria Intl
Apr 24
SJO9:00 amSan José Juan Santamaria Intl
11h 40m
2 stops
ECP9:40 pmPanama City NW Florida Beaches
$524
Southwest
Jul 10
ECP10:15 amPanama City NW Florida Beaches
10h 25m
1 stop
SJO7:40 pmSan José Juan Santamaria Intl
Jul 17
SJO8:45 amSan José Juan Santamaria Intl
11h 55m
2 stops
ECP9:40 pmPanama City NW Florida Beaches
$654
Southwest
Mar 14
ECP11:05 amPanama City NW Florida Beaches
9h 35m
2 stops
SJO7:40 pmSan José Juan Santamaria Intl
Mar 22
SJO8:45 amSan José Juan Santamaria Intl
11h 20m
2 stops
ECP9:05 pmPanama City NW Florida Beaches
$976

United Airlines flights from Panama City, Florida to Central America

Our best United Airlines deals on Panama City, Florida to Central America flight tickets
United Airlines
Apr 18
ECP6:30 amPanama City NW Florida Beaches
12h 07m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 22
PTY10:00 amPanama City Tocumen Intl
11h 59m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
$477
United Airlines
Apr 20
ECP6:30 amPanama City NW Florida Beaches
14h 07m
1 stop
SJO7:37 pmSan José Juan Santamaria Intl
Apr 24
SJO1:25 pmSan José Juan Santamaria Intl
7h 34m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
$526
United Airlines
Feb 9
ECP6:30 amPanama City NW Florida Beaches
14h 09m
1 stop
SJO8:39 pmSan José Juan Santamaria Intl
Feb 14
SJO2:20 pmSan José Juan Santamaria Intl
7h 36m
1 stop
ECP9:56 pmPanama City NW Florida Beaches
$533

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Sat 4/18

6:30 am-6:37 pm

1 stop12h 07m

Panama City Tocumen Intl

Wed 4/22

10:00 am-9:59 pm

1 stop11h 59m

$477

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 2/2

7:20 am-10:15 pm

1 stop14h 55m

San José Juan Santamaria Intl

Thu 2/5

7:00 am-7:50 pm

1 stop12h 50m

$515

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 4/20

6:30 am-6:50 pm

2 stops13h 20m

San José Juan Santamaria Intl

Fri 4/24

5:05 am-9:59 pm

2 stops15h 54m

$523

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 4/20

12:20 pm-7:00 pm

1 stop7h 40m

San José Juan Santamaria Intl

Fri 4/24

9:00 am-9:40 pm

2 stops11h 40m

$524

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 4/20

6:30 am-7:37 pm

1 stop14h 07m

San José Juan Santamaria Intl

Fri 4/24

1:25 pm-9:59 pm

1 stop7h 34m

$526

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Tue 3/17

8:20 am-7:12 pm

2 stops11h 52m

San José Juan Santamaria Intl

Tue 3/24

6:00 am-10:17 pm

2 stops15h 17m

$531

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Tue 3/17

12:39 pm-9:43 pm

1 stop10h 04m

San José Juan Santamaria Intl

Tue 3/24

2:20 pm-12:09 pm

1 stop20h 49m

$585

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Wed 3/18

6:41 am-9:43 pm

1 stop16h 02m

San José Juan Santamaria Intl

Sun 3/22

12:26 pm-10:06 am

2 stops20h 40m

$617

Panama CityLiberia

ECP - LIR

ECPLIR

Panama City NW Florida Beaches

Sat 2/21

6:00 am-12:50 pm

1 stop6h 50m

Liberia

Sat 2/28

3:05 pm-10:39 pm

1 stop7h 34m

$622

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 1/30

7:02 am-10:30 pm

2 stops15h 28m

San José Juan Santamaria Intl

Wed 2/4

6:00 am-5:33 pm

2 stops11h 33m

$697

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

How to get the cheapest flight ticket from Panama City, Florida to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, October is the cheapest month to fly from Panama City, Florida to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $478. If you don’t want to visit Central America in October, then you should wait until September to fly from Panama City, Florida, when ticket prices are also cheap, with an average price of $496.

Can stopping save me money on Panama City, Florida to Central America flights?

You could potentially save up to 36% on your flight if you consider stops on a Panama City, Florida to Central America flight.

Cheap Panama City, Florida to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Central America

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Panama City, Florida to Central America takes 6h 50m
There are no direct flights from Panama City, Florida to Central America. There are no popular flight routes from Panama City, Florida to Central America.
Search flight deals

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Central America?

    Prices for flights from Panama City NW Florida Beaches Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Central America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Central America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to Central America

Compare and see reviews for airlines that fly from Panama City, Florida to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $395Free CancellationRating
7.9
8,124 reviews
Search Delta flights
United AirlinesPriceFrom $397Free CancellationRating
7.4
9,212 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Central America?

Finding the right flight to Central America from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Panama City to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Panama City with this policy.

How can momondo help me find flights from Panama City to Central America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Central America from Panama City.

I’m not ready to book a flight from Panama City to Central America right now. Can momondo alert me if prices change?

Price alerts on flights to Central America from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Central America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 2/27
Fri 3/6
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
Flights to San Joséfrom $143
Flights to San Salvadorfrom $108
Flights to Guatemala Cityfrom $80
Flights to Panama Cityfrom $278
Flights to Managuafrom $178
Flights to Liberiafrom $224
Flights to San Pedro Sulafrom $110
Flights to Belize Cityfrom $237
Flights to Coxen Holefrom $364
Flights to Floresfrom $422
Flights to Bocas del Torofrom $653
Flights to Davidfrom $410