Cheap flights from Panama City, Florida to Central America from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Central America departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Central America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
12:20 pm - 7:00 pm
ECP
-
SJO
7h 40m
1 stop
Southwest Logo
9:00 am - 10:10 am
SJO
-
ECP
24h 10m
2 stops
$496Southwest
Fri, May 15 - Fri, May 22
Southwest Logo
7:00 am - 7:40 pm
ECP
-
SJO
13h 40m
2 stops
Southwest Logo
8:45 am - 8:10 pm
SJO
-
ECP
10h 25m
2 stops
$508Southwest
Tue, Jul 28 - Fri, Jul 31
Southwest Logo
9:45 am - 7:00 pm
ECP
-
SJO
10h 15m
2 stops
Southwest Logo
9:00 am - 9:05 pm
SJO
-
ECP
11h 05m
2 stops
$526Southwest
Sun, May 17 - Sun, May 24
United Airlines Logo
6:30 am - 6:37 pm
ECP
-
PTY
12h 07m
1 stop
United Airlines Logo
7:55 am - 10:05 pm
PTY
-
ECP
14h 10m
1 stop
$547United Airlines
Mon, Apr 27 - Mon, May 4
Southwest Logo
10:10 am - 7:00 pm
ECP
-
SJO
9h 50m
1 stop
Southwest Logo
9:00 am - 8:45 pm
SJO
-
ECP
10h 45m
2 stops
$550Southwest
Tue, Apr 28 - Tue, May 5
Southwest Logo
12:20 pm - 7:00 pm
ECP
-
SJO
7h 40m
1 stop
Southwest Logo
9:00 am - 9:40 pm
SJO
-
ECP
11h 40m
2 stops
$562Southwest
Mon, May 11 - Mon, May 18
United Airlines Logo
6:30 am - 2:14 pm
ECP
-
PTY
7h 44m
1 stop
United Airlines Logo
3:30 pm - 9:35 am
PTY
-
ECP
18h 05m
1 stop
$567United Airlines
Mon, Apr 13 - Tue, Apr 14
American Airlines Logo
10:48 am - 7:07 pm
ECP
-
SJO
9h 19m
2 stops
American Airlines Logo
1:59 pm - 11:40 pm
SJO
-
ECP
8h 41m
1 stop
$601American Airlines
Mon, May 18 - Fri, May 22
American Airlines Logo
10:48 am - 11:35 am
ECP
-
SJO
25h 47m
1 stop
American Airlines Logo
1:59 pm - 11:40 pm
SJO
-
ECP
8h 41m
1 stop
$605American Airlines
Mon, May 18 - Fri, May 22
Delta Logo
6:00 am - 12:00 pm
ECP
-
LIR
7h 00m
1 stop
Delta Logo
1:25 pm - 10:46 pm
LIR
-
ECP
8h 21m
1 stop
$710Delta
Sun, Aug 16 - Sat, Aug 22

Southwest flights from Panama City, Florida to Central America

Our best Southwest deals on Panama City, Florida to Central America flight tickets
Southwest
May 15
ECP12:20 pmPanama City NW Florida Beaches
7h 40m
1 stop
SJO7:00 pmSan José Juan Santamaria Intl
May 22
SJO9:00 amSan José Juan Santamaria Intl
24h 10m
2 stops
ECP10:10 amPanama City NW Florida Beaches
$496
Southwest
May 17
ECP9:45 amPanama City NW Florida Beaches
10h 15m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
May 24
SJO9:00 amSan José Juan Santamaria Intl
11h 05m
2 stops
ECP9:05 pmPanama City NW Florida Beaches
$526
Southwest
Apr 28
ECP10:10 amPanama City NW Florida Beaches
9h 50m
1 stop
SJO7:00 pmSan José Juan Santamaria Intl
May 5
SJO9:00 amSan José Juan Santamaria Intl
10h 45m
2 stops
ECP8:45 pmPanama City NW Florida Beaches
$550

Delta flights from Panama City, Florida to Central America

Our best Delta deals on Panama City, Florida to Central America flight tickets
Delta
Apr 18
ECP5:49 amPanama City NW Florida Beaches
7h 07m
1 stop
SJO11:56 amSan José Juan Santamaria Intl
May 1
SJO1:21 pmSan José Juan Santamaria Intl
8h 51m
1 stop
ECP11:12 pmPanama City NW Florida Beaches
$584
Delta
Aug 16
ECP6:00 amPanama City NW Florida Beaches
7h 00m
1 stop
LIR12:00 pmLiberia
Aug 22
LIR1:25 pmLiberia
8h 21m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
$710
Delta
Sep 14
ECP6:00 amPanama City NW Florida Beaches
6h 54m
1 stop
SJO11:54 amSan José Juan Santamaria Intl
Sep 23
SJO1:25 pmSan José Juan Santamaria Intl
8h 21m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
$720

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 5/15

12:20 pm-7:00 pm

1 stop7h 40m

San José Juan Santamaria Intl

Fri 5/22

9:00 am-10:10 am

2 stops24h 10m

$496

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Tue 7/28

7:00 am-7:40 pm

2 stops13h 40m

San José Juan Santamaria Intl

Fri 7/31

8:45 am-8:10 pm

2 stops10h 25m

$508

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Sun 5/17

9:45 am-7:00 pm

2 stops10h 15m

San José Juan Santamaria Intl

Sun 5/24

9:00 am-9:05 pm

2 stops11h 05m

$526

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Mon 4/27

6:30 am-6:37 pm

1 stop12h 07m

Panama City Tocumen Intl

Mon 5/4

7:55 am-10:05 pm

1 stop14h 10m

$547

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Tue 4/28

10:10 am-7:00 pm

1 stop9h 50m

San José Juan Santamaria Intl

Tue 5/5

9:00 am-8:45 pm

2 stops10h 45m

$550

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 5/11

12:20 pm-7:00 pm

1 stop7h 40m

San José Juan Santamaria Intl

Mon 5/18

9:00 am-9:40 pm

2 stops11h 40m

$562

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Mon 4/13

6:30 am-2:14 pm

1 stop7h 44m

Panama City Tocumen Intl

Tue 4/14

3:30 pm-9:35 am

1 stop18h 05m

$567

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 5/18

10:48 am-7:07 pm

2 stops9h 19m

San José Juan Santamaria Intl

Fri 5/22

1:59 pm-11:40 pm

1 stop8h 41m

$601

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Mon 5/18

10:48 am-11:35 am

1 stop25h 47m

San José Juan Santamaria Intl

Fri 5/22

1:59 pm-11:40 pm

1 stop8h 41m

$605
Quickest round-trip

Panama CityLiberia

ECP - LIR

ECPLIR

Panama City NW Florida Beaches

Sun 8/16

6:00 am-12:00 pm

1 stop7h 00m

Liberia

Sat 8/22

1:25 pm-10:46 pm

1 stop8h 21m

$710

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, October is the cheapest month to fly from Panama City, Florida to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $478. If you don’t want to visit Central America in October, then you should wait until September to fly from Panama City, Florida, when ticket prices are also cheap, with an average price of $496.

Can stopping save me money on Panama City, Florida to Central America flights?

You could potentially save up to 36% on your flight if you consider stops on a Panama City, Florida to Central America flight.

Cheap Panama City, Florida to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Central America

Fastest flight time

6h 40m

Direct flights

None
The fastest flight from Panama City, Florida to Central America takes 6h 40m
There are no direct flights from Panama City, Florida to Central America. There are no popular flight routes from Panama City, Florida to Central America.
  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Central America?

    Prices for flights from Panama City NW Florida Beaches Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Central America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Central America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to Central America

Compare and see reviews for airlines that fly from Panama City, Florida to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $395Free CancellationRating
7.9
8,286 reviews
Search Delta flights
United AirlinesPriceFrom $397Free CancellationRating
7.4
9,435 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Central America?

Finding the right flight to Central America from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Panama City to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Panama City with this policy.

How can momondo help me find flights from Panama City to Central America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Central America from Panama City.

I’m not ready to book a flight from Panama City to Central America right now. Can momondo alert me if prices change?

Price alerts on flights to Central America from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Central America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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1 adult
Fri 4/17
Fri 4/24

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Popular flights according to clicks in the last 7 days on momondo