Cheap flights from Panama City, Florida to Central America from $231

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Central America departing on 12/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Central America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 am - 1:45 pmECP-PTY
7h 15m1 stop
United Airlines Logo
3:41 pm - 12:04 pmPTY-ECP
20h 23m1 stop
$444United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
American Airlines Logo
1:34 pm - 1:27 pmECP-PTY
22h 53m2 stops
American Airlines Logo
4:50 pm - 2:54 pmPTY-ECP
23h 04m2 stops
$480American Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 19
United Airlines Logo
6:30 am - 5:07 pmECP-PTY
9h 37m1 stop
United Airlines Logo
4:41 pm - 4:12 pmPTY-ECP
24h 31m1 stop
$484United Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 19
American Airlines Logo
3:27 pm - 3:38 pmECP-PTY
23h 11m2 stops
American Airlines Logo
4:50 pm - 2:54 pmPTY-ECP
23h 04m2 stops
$500American Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 19
Delta Logo
1:10 pm - 10:15 pmECP-SJO
9h 05m1 stop
Delta Logo
7:00 am - 10:43 pmSJO-ECP
15h 43m1 stop
$506Delta
Find Deal
Sat, Jan 31 - Thu, Feb 19
American Airlines Logo
3:27 pm - 11:43 pmECP-SJO
8h 16m1 stop
American Airlines Logo
6:38 am - 9:19 pmSJO-ECP
14h 41m1 stop
$512American Airlines
Find Deal
Fri, Jan 16 - Thu, Jan 22
Delta Logo
7:20 am - 1:50 pmECP-LIR
6h 30m1 stop
Delta Logo
2:05 pm - 10:40 pmLIR-ECP
8h 35m1 stop
$513Delta
Find Deal
Sun, Jan 18 - Thu, Jan 22
American Airlines Logo
7:02 am - 11:43 pmECP-SJO
16h 41m1 stop
American Airlines Logo
2:54 pm - 11:33 amSJO-ECP
20h 39m2 stops
$516American Airlines
Find Deal
Thu, Jan 8 - Thu, Jan 15
United Airlines Logo
6:30 am - 2:45 pmECP-PTY
7h 15m1 stop
United Airlines Logo
4:41 pm - 12:02 pmPTY-ECP
20h 21m1 stop
$520United Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 19
Air France Logo
1:10 pm - 10:15 pmECP-SJO
9h 05m1 stop
Air France Logo
2:25 pm - 10:43 pmSJO-ECP
8h 18m1 stop
$608Air France
Find Deal
Sat, Jan 31 - Thu, Feb 19

Delta flights from Panama City, Florida to Central America

Our best Delta deals on Panama City, Florida to Central America flight tickets
Delta
Jan 31
ECP1:10 pmPanama City NW Florida Beaches
9h 05m
1 stop
SJO10:15 pmSan José Juan Santamaria Intl
Feb 19
SJO7:00 amSan José Juan Santamaria Intl
15h 43m
1 stop
ECP10:43 pmPanama City NW Florida Beaches
Delta
Jan 18
ECP7:20 amPanama City NW Florida Beaches
6h 30m
1 stop
LIR1:50 pmLiberia
Jan 22
LIR2:05 pmLiberia
8h 35m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Delta
Jan 7
ECP7:20 amPanama City NW Florida Beaches
14h 55m
1 stop
SJO10:15 pmSan José Juan Santamaria Intl
Jan 21
SJO7:00 amSan José Juan Santamaria Intl
15h 40m
1 stop
ECP10:40 pmPanama City NW Florida Beaches

American Airlines flights from Panama City, Florida to Central America

Our best American Airlines deals on Panama City, Florida to Central America flight tickets
American Airlines
Jan 8
ECP1:34 pmPanama City NW Florida Beaches
22h 53m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 19
PTY4:50 pmPanama City Tocumen Intl
23h 04m
2 stops
ECP2:54 pmPanama City NW Florida Beaches
American Airlines
Jan 13
ECP6:03 pmPanama City NW Florida Beaches
19h 51m
2 stops
SJO1:54 pmSan José Juan Santamaria Intl
Jan 16
SJO4:02 pmSan José Juan Santamaria Intl
21h 08m
2 stops
ECP1:10 pmPanama City NW Florida Beaches
American Airlines
Jan 8
ECP12:03 pmPanama City NW Florida Beaches
24h 24m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 19
PTY4:50 pmPanama City Tocumen Intl
23h 04m
2 stops
ECP2:54 pmPanama City NW Florida Beaches

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 2, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Tue 3/10

6:30 am-1:45 pm

1 stop7h 15m

Panama City Tocumen Intl

Wed 3/11

3:41 pm-12:04 pm

1 stop20h 23m

$444

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

1:34 pm-1:27 pm

2 stops22h 53m

Panama City Tocumen Intl

Mon 1/19

4:50 pm-2:54 pm

2 stops23h 04m

$480

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

6:30 am-5:07 pm

1 stop9h 37m

Panama City Tocumen Intl

Mon 1/19

4:41 pm-4:12 pm

1 stop24h 31m

$484

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

3:27 pm-3:38 pm

2 stops23h 11m

Panama City Tocumen Intl

Mon 1/19

4:50 pm-2:54 pm

2 stops23h 04m

$500

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Sat 1/31

1:10 pm-10:15 pm

1 stop9h 05m

San José Juan Santamaria Intl

Thu 2/19

7:00 am-10:43 pm

1 stop15h 43m

$506

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Fri 1/16

3:27 pm-11:43 pm

1 stop8h 16m

San José Juan Santamaria Intl

Thu 1/22

6:38 am-9:19 pm

1 stop14h 41m

$512

Panama CityLiberia

ECP - LIR

ECPLIR

Panama City NW Florida Beaches

Sun 1/18

7:20 am-1:50 pm

1 stop6h 30m

Liberia

Thu 1/22

2:05 pm-10:40 pm

1 stop8h 35m

$513

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Thu 1/8

7:02 am-11:43 pm

1 stop16h 41m

San José Juan Santamaria Intl

Thu 1/15

2:54 pm-11:33 am

2 stops20h 39m

$516

Panama CityPanama City

ECP - PTY

ECPPTY

Panama City NW Florida Beaches

Thu 1/8

6:30 am-2:45 pm

1 stop7h 15m

Panama City Tocumen Intl

Mon 1/19

4:41 pm-12:02 pm

1 stop20h 21m

$520

Panama CitySan José

ECP - SJO

ECPSJO

Panama City NW Florida Beaches

Sat 1/31

1:10 pm-10:15 pm

1 stop9h 05m

San José Juan Santamaria Intl

Thu 2/19

2:25 pm-10:43 pm

1 stop8h 18m

$608

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, October is the cheapest month to fly from Panama City, Florida to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $478. If you don’t want to visit Central America in October, then you should wait until September to fly from Panama City, Florida, when ticket prices are also cheap, with an average price of $496.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Panama City, Florida to Central America is on a Wednesday. Travelers who choose to depart for Central America on a Wednesday will often find tickets for as low as $543. On the other hand, Monday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $810.

Can stopping save me money on Panama City, Florida to Central America flights?

You could potentially save up to 36% on your flight if you consider stops on a Panama City, Florida to Central America flight.

Cheap Panama City, Florida to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Central America

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from Panama City, Florida to Central America takes 6h 30m
There are no direct flights from Panama City, Florida to Central America. There are no popular flight routes from Panama City, Florida to Central America.
  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Central America?

    Prices for flights from Panama City NW Florida Beaches Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Central America?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Central America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to Central America

Compare and see reviews for airlines that fly from Panama City, Florida to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $395Free CancellationRating
7.9
8,011 reviews
Search Delta flights
United AirlinesPriceFrom $397Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Central America?

Finding the right flight to Central America from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Panama City to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Panama City with this policy.

How can momondo help me find flights from Panama City to Central America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Central America from Panama City.

I’m not ready to book a flight from Panama City to Central America right now. Can momondo alert me if prices change?

Price alerts on flights to Central America from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Central America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Thu 1/1
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