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Cheap flights from Myrtle Beach to Chicago from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 6/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:55 am - 9:00 am
MYR
-
MDW
2h 05mnonstop
Southwest Logo
6:45 pm - 9:45 pm
MDW
-
MYR
2h 00mnonstop
$217Southwest
Wed, Jun 10 - Tue, Jun 16
Southwest Logo
7:15 pm - 11:10 pm
MYR
-
MDW
4h 55m
1 stop
Southwest Logo
6:45 pm - 9:45 pm
MDW
-
MYR
2h 00mnonstop
$227Southwest
Wed, Jun 10 - Tue, Jun 16
Southwest Logo
7:55 am - 9:00 am
MYR
-
MDW
2h 05mnonstop
Southwest Logo
11:25 am - 8:30 pm
MDW
-
MYR
8h 05m
2 stops
$232Southwest
Wed, Jun 10 - Tue, Jun 16
Southwest Logo
7:15 pm - 11:10 pm
MYR
-
MDW
4h 55m
1 stop
Southwest Logo
11:25 am - 8:30 pm
MDW
-
MYR
8h 05m
2 stops
$242Southwest
Wed, Jun 10 - Tue, Jun 16
Delta Logo
6:00 am - 12:05 pm
MYR
-
MDW
7h 05m
1 stop
Delta Logo
11:05 am - 7:07 pm
MDW
-
MYR
7h 02m
1 stop
$247Delta
Wed, Jun 17 - Wed, Jun 24
Southwest Logo
7:35 am - 10:40 am
MYR
-
MDW
4h 05m
1 stop
Southwest Logo
7:45 pm - 10:45 pm
MDW
-
MYR
2h 00mnonstop
$250Southwest
Wed, Jun 3 - Thu, Jun 4
Southwest Logo
11:15 am - 4:45 pm
MYR
-
MDW
6h 30m
1 stop
Southwest Logo
6:05 pm - 9:05 pm
MDW
-
MYR
2h 00mnonstop
$254Southwest
Wed, Jun 3 - Sat, Jun 6
Southwest Logo
7:55 am - 9:00 am
MYR
-
MDW
2h 05mnonstop
Southwest Logo
6:45 pm - 9:45 pm
MDW
-
MYR
2h 00mnonstop
$257Southwest
Wed, Jun 10 - Tue, Jun 16
Southwest Logo
2:10 pm - 7:35 pm
MYR
-
MDW
6h 25m
2 stops
Southwest Logo
7:45 pm - 10:45 pm
MDW
-
MYR
2h 00mnonstop
$259Southwest
Wed, Jun 3 - Thu, Jun 4
Southwest Logo
6:35 am - 7:45 am
MYR
-
MDW
2h 10mnonstop
Southwest Logo
6:45 pm - 9:45 pm
MDW
-
MYR
2h 00mnonstop
$266Southwest
Sat, Jun 13 - Tue, Jun 16

Southwest flights from Myrtle Beach to Chicago Midway Airport

Our best Southwest deals on Myrtle Beach to Chicago Midway Airport flight tickets
Southwest
Jun 10
MYR7:55 amMyrtle Beach Intl
2h 05m
MDW9:00 amChicago Midway
Jun 16
MDW6:45 pmChicago Midway
2h 00m
MYR9:45 pmMyrtle Beach Intl
$217
Southwest
Jun 10
MYR7:15 pmMyrtle Beach Intl
4h 55m
1 stop
MDW11:10 pmChicago Midway
Jun 16
MDW6:45 pmChicago Midway
2h 00m
MYR9:45 pmMyrtle Beach Intl
$227
Southwest
Jun 10
MYR7:55 amMyrtle Beach Intl
2h 05m
MDW9:00 amChicago Midway
Jun 16
MDW11:25 amChicago Midway
8h 05m
2 stops
MYR8:30 pmMyrtle Beach Intl
$232

Delta flights from Myrtle Beach to Chicago Midway Airport

Our best Delta deals on Myrtle Beach to Chicago Midway Airport flight tickets
Delta
Jun 17
MYR6:00 amMyrtle Beach Intl
7h 05m
1 stop
MDW12:05 pmChicago Midway
Jun 24
MDW11:05 amChicago Midway
7h 02m
1 stop
MYR7:07 pmMyrtle Beach Intl
$247
Delta
Sep 24
MYR6:00 amMyrtle Beach Intl
4h 50m
1 stop
MDW9:50 amChicago Midway
Sep 29
MDW5:25 pmChicago Midway
5h 14m
1 stop
MYR11:39 pmMyrtle Beach Intl
$264
Delta
Jun 17
MYR6:00 amMyrtle Beach Intl
5h 09m
1 stop
MDW10:09 amChicago Midway
Jun 19
MDW11:05 amChicago Midway
7h 02m
1 stop
MYR7:07 pmMyrtle Beach Intl
$306

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/10

7:55 am-9:00 am

Nonstop2h 05m

Chicago Midway

Tue 6/16

6:45 pm-9:45 pm

Nonstop2h 00m

$217

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/10

7:15 pm-11:10 pm

1 stop4h 55m

Chicago Midway

Tue 6/16

6:45 pm-9:45 pm

Nonstop2h 00m

$227

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/10

7:55 am-9:00 am

Nonstop2h 05m

Chicago Midway

Tue 6/16

11:25 am-8:30 pm

2 stops8h 05m

$232

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/10

7:15 pm-11:10 pm

1 stop4h 55m

Chicago Midway

Tue 6/16

11:25 am-8:30 pm

2 stops8h 05m

$242

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/17

6:00 am-12:05 pm

1 stop7h 05m

Chicago Midway

Wed 6/24

11:05 am-7:07 pm

1 stop7h 02m

$247

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/3

7:35 am-10:40 am

1 stop4h 05m

Chicago Midway

Thu 6/4

7:45 pm-10:45 pm

Nonstop2h 00m

$250

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/3

11:15 am-4:45 pm

1 stop6h 30m

Chicago Midway

Sat 6/6

6:05 pm-9:05 pm

Nonstop2h 00m

$254

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/10

7:55 am-9:00 am

Nonstop2h 05m

Chicago Midway

Tue 6/16

6:45 pm-9:45 pm

Nonstop2h 00m

$257

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 6/3

2:10 pm-7:35 pm

2 stops6h 25m

Chicago Midway

Thu 6/4

7:45 pm-10:45 pm

Nonstop2h 00m

$259

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Sat 6/13

6:35 am-7:45 am

Nonstop2h 10m

Chicago Midway

Tue 6/16

6:45 pm-9:45 pm

Nonstop2h 00m

$266

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Wednesday is the cheapest day to fly to Chicago Midway Airport from Myrtle Beach. The lowest ticket price found for a Wednesday departure recently was $373. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Sunday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $528.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Myrtle Beach at noon is the least expensive time of day to depart. momondo users have found prices as low as $427 when looking at flights departing at noon. Try not to purchase tickets in the morning because they tend to be around $430. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Myrtle Beach Intl to Chicago Midway flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago Midway flight prices

Can stopping save me money on Myrtle Beach to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago Midway Airport.

When to book flights from Myrtle Beach to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago Midway Airport (MYR to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago Midway Airport

Best Price Found

$203

Fastest flight time

2h 05m

Direct flights

Every day
The best one-way flight to Chicago Midway Airport from Myrtle Beach in the past 72 hours is $203. The best round-trip flight deal from Myrtle Beach to Chicago Midway Airport found on momondo in the last 72 hours is $355.
The fastest flight from Myrtle Beach to Chicago Midway Airport takes 2h 05m
Direct flights go from Myrtle Beach to Chicago Midway Airport every day.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Chicago Midway Airport

  • How far is Myrtle Beach Intl to Chicago Midway by plane?

    The distance between Myrtle Beach Intl and Chicago Midway is about 738.5 mi. By plane, this route typically takes 2h 05m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago Midway Airport?

  • What is the most popular airline from Myrtle Beach to Chicago Midway Airport?

Best airlines flying from Myrtle Beach to Chicago Midway Airport

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $271Free CancellationRating
7.9
4,302 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago Midway Airport

    Southwest operates around 2 flights from Myrtle Beach to Chicago Midway Airport every week. The average price of these flights found in the last 72 hours has been $416, but momondo users have found Southwest deals from Myrtle Beach to Chicago Midway Airport from as low as $271 round-trip. Southwest has been scored 7.9/10 in 4,302 reviews.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Saint Joseph
Benton Harbor
Portage
Lansing
Valparaiso
Munster
Schererville
Crown Point
Monticello
Chesterton
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Chicago.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Myrtle Beach and alert you when they change.

An easier way to manage your Chicago Midway Airport trip

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