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Cheap flights from Myrtle Beach to Chicago from $91

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Multiple Airlines Logo
8:59 pm - 1:01 pmMYR-MDW
17h 02m1 stop
Multiple Airlines Logo
7:23 pm - 5:48 pmMDW-MYR
45h 25m2 stops
$233Multiple Airlines
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Wed, Dec 3 - Thu, Dec 11
Multiple Airlines Logo
8:59 pm - 1:01 pmMYR-MDW
17h 02m1 stop
Multiple Airlines Logo
7:44 am - 4:46 pmMDW-MYR
8h 02m1 stop
$251Multiple Airlines
Find Deal
Wed, Dec 3 - Thu, Dec 11
Multiple Airlines Logo
2:46 pm - 8:46 amMYR-MDW
19h 00m2 stops
Multiple Airlines Logo
7:44 am - 8:00 amMDW-MYR
23h 16m1 stop
$254Multiple Airlines
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Tue, Dec 2 - Thu, Dec 11
Southwest Logo
2:55 pm - 4:05 pmMYR-MDW
2h 10mnonstop
Southwest Logo
2:30 pm - 5:25 pmMDW-MYR
1h 55mnonstop
$332Southwest
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Wed, Dec 3 - Thu, Dec 11
Southwest Logo
2:55 pm - 4:05 pmMYR-MDW
2h 10mnonstop
Southwest Logo
8:50 am - 2:15 pmMDW-MYR
4h 25m1 stop
$342Southwest
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Wed, Dec 3 - Thu, Dec 11
Southwest Logo
2:55 pm - 4:05 pmMYR-MDW
2h 10mnonstop
Southwest Logo
2:30 pm - 5:25 pmMDW-MYR
1h 55mnonstop
$360Southwest
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Tue, Dec 2 - Wed, Dec 3
Delta Logo
6:00 am - 9:58 amMYR-MDW
4h 58m1 stop
Delta Logo
6:40 pm - 11:58 pmMDW-MYR
4h 18m1 stop
$361Delta
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Thu, Feb 26 - Mon, Mar 2
Southwest Logo
8:00 am - 4:00 pmMYR-MDW
9h 00m2 stops
Southwest Logo
6:20 am - 2:15 pmMDW-MYR
6h 55m2 stops
$362Southwest
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Wed, Dec 3 - Thu, Dec 11
Delta Logo
6:00 am - 11:55 amMYR-MDW
6h 55m1 stop
Delta Logo
10:49 am - 6:01 pmMDW-MYR
6h 12m1 stop
$380Delta
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Fri, Dec 12 - Tue, Dec 16
Delta Logo
6:00 am - 9:56 amMYR-MDW
4h 56m1 stop
Delta Logo
1:05 pm - 5:56 pmMDW-MYR
3h 51m1 stop
$417Delta
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Tue, Mar 10 - Wed, Mar 11

Southwest flights from Myrtle Beach to Chicago Midway Airport

Our best Southwest deals on Myrtle Beach to Chicago Midway Airport flight tickets
Southwest
Dec 3
MYR2:55 pmMyrtle Beach Intl
2h 10m
MDW4:05 pmChicago Midway
Dec 11
MDW2:30 pmChicago Midway
1h 55m
MYR5:25 pmMyrtle Beach Intl
$332
Find similar
Southwest
Dec 3
MYR2:55 pmMyrtle Beach Intl
2h 10m
MDW4:05 pmChicago Midway
Dec 11
MDW8:50 amChicago Midway
4h 25m
1 stop
MYR2:15 pmMyrtle Beach Intl
$342
Find similar
Southwest
Dec 2
MYR2:55 pmMyrtle Beach Intl
2h 10m
MDW4:05 pmChicago Midway
Dec 3
MDW2:30 pmChicago Midway
1h 55m
MYR5:25 pmMyrtle Beach Intl
$360
Find similar

Delta flights from Myrtle Beach to Chicago Midway Airport

Our best Delta deals on Myrtle Beach to Chicago Midway Airport flight tickets
Delta
Feb 26
MYR6:00 amMyrtle Beach Intl
4h 58m
1 stop
MDW9:58 amChicago Midway
Mar 2
MDW6:40 pmChicago Midway
4h 18m
1 stop
MYR11:58 pmMyrtle Beach Intl
$361
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Delta
Dec 12
MYR6:00 amMyrtle Beach Intl
6h 55m
1 stop
MDW11:55 amChicago Midway
Dec 16
MDW10:49 amChicago Midway
6h 12m
1 stop
MYR6:01 pmMyrtle Beach Intl
$380
Find similar
Delta
Mar 10
MYR6:00 amMyrtle Beach Intl
4h 56m
1 stop
MDW9:56 amChicago Midway
Mar 11
MDW1:05 pmChicago Midway
3h 51m
1 stop
MYR5:56 pmMyrtle Beach Intl
$417
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momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/3

8:59 pm-1:01 pm

1 stop17h 02m

Chicago Midway

Thu 12/11

7:23 pm-5:48 pm

2 stops45h 25m

$233

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/3

8:59 pm-1:01 pm

1 stop17h 02m

Chicago Midway

Thu 12/11

7:44 am-4:46 pm

1 stop8h 02m

$251

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 12/2

2:46 pm-8:46 am

2 stops19h 00m

Chicago Midway

Thu 12/11

7:44 am-8:00 am

1 stop23h 16m

$254

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/3

2:55 pm-4:05 pm

Nonstop2h 10m

Chicago Midway

Thu 12/11

2:30 pm-5:25 pm

Nonstop1h 55m

$332

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/3

2:55 pm-4:05 pm

Nonstop2h 10m

Chicago Midway

Thu 12/11

8:50 am-2:15 pm

1 stop4h 25m

$342

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 12/2

2:55 pm-4:05 pm

Nonstop2h 10m

Chicago Midway

Wed 12/3

2:30 pm-5:25 pm

Nonstop1h 55m

$360

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Thu 2/26

6:00 am-9:58 am

1 stop4h 58m

Chicago Midway

Mon 3/2

6:40 pm-11:58 pm

1 stop4h 18m

$361

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/3

8:00 am-4:00 pm

2 stops9h 00m

Chicago Midway

Thu 12/11

6:20 am-2:15 pm

2 stops6h 55m

$362

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 12/12

6:00 am-11:55 am

1 stop6h 55m

Chicago Midway

Tue 12/16

10:49 am-6:01 pm

1 stop6h 12m

$380

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 3/10

6:00 am-9:56 am

1 stop4h 56m

Chicago Midway

Wed 3/11

1:05 pm-5:56 pm

1 stop3h 51m

$417

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Tuesday is the cheapest day to fly to Chicago Midway Airport from Myrtle Beach. The lowest ticket price found for a Tuesday departure recently was $407. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Saturday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $461.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Myrtle Beach in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $407 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $453. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Myrtle Beach Intl to Chicago Midway flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago Midway flight prices

What cabin class options are available on Myrtle Beach Intl to Chicago Midway flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago Midway Airport flights?

You could potentially save up to 24% on your flight if you consider stops on a Myrtle Beach to Chicago Midway Airport flight.

When to book flights from Myrtle Beach to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago Midway Airport (MYR to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago Midway Airport

Best Price Found

$184

Fastest flight time

2h 10m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun
The best one-way flight to Chicago Midway Airport from Myrtle Beach in the past 72 hours is $184. The best round-trip flight deal from Myrtle Beach to Chicago Midway Airport found on momondo in the last 72 hours is $366.
The fastest flight from Myrtle Beach to Chicago Midway Airport takes 2h 10m
Direct flights go from Myrtle Beach to Chicago Midway Airport on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
Search flight deals

  • How far is Myrtle Beach Intl to Chicago Midway by plane?

    The distance between Myrtle Beach Intl and Chicago Midway is about 738.5 mi. By plane, this route typically takes 2h 10m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago Midway Airport?

  • What is the most popular airline from Myrtle Beach to Chicago Midway Airport?

Best airlines flying from Myrtle Beach to Chicago Midway Airport

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $239Free CancellationRating
8.0
4,240 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago Midway Airport

    Southwest operates around 6 flights from Myrtle Beach to Chicago Midway Airport every week. The average price of these flights found in the last 72 hours has been $389, but momondo users have found Southwest deals from Myrtle Beach to Chicago Midway Airport from as low as $239 round-trip. Southwest has been scored 8.0/10 in 4,240 reviews.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Crown Point
Munster
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Chicago.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Myrtle Beach and alert you when they change.

An easier way to manage your Chicago Midway Airport trip

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