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Cheap flights from Myrtle Beach to Chicago from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:31 pm - 1:00 pm
MYR
-
MDW
17h 29m
1 stop
Multiple Airlines Logo
7:30 am - 3:50 pm
MDW
-
MYR
7h 20m
1 stop
$202Multiple Airlines
Tue, Apr 21 - Sat, Apr 25
Multiple Airlines Logo
8:31 pm - 1:00 pm
MYR
-
MDW
17h 29m
1 stop
Multiple Airlines Logo
7:30 am - 8:44 am
MDW
-
MYR
24h 14m
1 stop
$205Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
Multiple Airlines Logo
8:43 pm - 1:00 pm
MYR
-
MDW
17h 17m
1 stop
Multiple Airlines Logo
7:30 am - 7:04 pm
MDW
-
MYR
10h 34m
1 stop
$217Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
8:31 pm - 1:00 pm
MYR
-
MDW
17h 29m
1 stop
Multiple Airlines Logo
7:30 am - 11:29 pm
MDW
-
MYR
14h 59m
2 stops
$220Multiple Airlines
Tue, Apr 21 - Sat, Apr 25
Southwest Logo
11:15 am - 3:45 pm
MYR
-
MDW
5h 30m
2 stops
Southwest Logo
9:50 am - 5:35 pm
MDW
-
MYR
6h 45m
1 stop
$222Southwest
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
11:15 am - 3:45 pm
MYR
-
MDW
5h 30m
2 stops
Southwest Logo
7:50 am - 3:25 pm
MDW
-
MYR
6h 35m
2 stops
$227Southwest
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
8:31 pm - 1:00 pm
MYR
-
MDW
17h 29m
1 stop
Multiple Airlines Logo
6:10 am - 4:31 pm
MDW
-
MYR
9h 21m
2 stops
$240Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
Southwest Logo
11:15 am - 3:45 pm
MYR
-
MDW
5h 30m
2 stops
Southwest Logo
10:15 am - 8:45 pm
MDW
-
MYR
9h 30m
2 stops
$264Southwest
Tue, Apr 21 - Sat, Apr 25
Multiple Airlines Logo
8:43 pm - 1:00 pm
MYR
-
MDW
17h 17m
1 stop
Multiple Airlines Logo
7:30 am - 7:04 pm
MDW
-
MYR
10h 34m
1 stop
$273Multiple Airlines
Fri, Apr 24 - Sun, Apr 26
Multiple Airlines Logo
11:52 am - 10:19 pm
MYR
-
MDW
11h 27m
2 stops
Multiple Airlines Logo
7:30 am - 7:04 pm
MDW
-
MYR
10h 34m
1 stop
$276Multiple Airlines
Thu, Apr 23 - Sun, Apr 26

Southwest flights from Myrtle Beach to Chicago Midway Airport

Our best Southwest deals on Myrtle Beach to Chicago Midway Airport flight tickets
Southwest
Apr 21
MYR11:15 amMyrtle Beach Intl
5h 30m
2 stops
MDW3:45 pmChicago Midway
Apr 25
MDW10:15 amChicago Midway
9h 30m
2 stops
MYR8:45 pmMyrtle Beach Intl
$264
Southwest
Apr 21
MYR2:10 pmMyrtle Beach Intl
6h 20m
1 stop
MDW7:30 pmChicago Midway
Apr 25
MDW8:05 amChicago Midway
2h 00m
MYR11:05 amMyrtle Beach Intl
$279
Southwest
May 12
MYR7:35 amMyrtle Beach Intl
4h 05m
1 stop
MDW10:40 amChicago Midway
May 17
MDW1:10 pmChicago Midway
2h 00m
MYR4:10 pmMyrtle Beach Intl
$313

Delta flights from Myrtle Beach to Chicago Midway Airport

Our best Delta deals on Myrtle Beach to Chicago Midway Airport flight tickets
Delta
Apr 23
MYR12:50 pmMyrtle Beach Intl
6h 08m
1 stop
MDW5:58 pmChicago Midway
Apr 27
MDW5:21 pmChicago Midway
5h 53m
1 stop
MYR12:14 amMyrtle Beach Intl
$291
Delta
Jun 4
MYR4:07 pmMyrtle Beach Intl
6h 02m
1 stop
MDW9:09 pmChicago Midway
Jun 9
MDW6:00 amChicago Midway
5h 19m
1 stop
MYR12:19 pmMyrtle Beach Intl
$358
Delta
May 14
MYR4:07 pmMyrtle Beach Intl
6h 02m
1 stop
MDW9:09 pmChicago Midway
May 18
MDW5:10 pmChicago Midway
5h 48m
1 stop
MYR11:58 pmMyrtle Beach Intl
$364

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

8:31 pm-1:00 pm

1 stop17h 29m

Chicago Midway

Sat 4/25

7:30 am-3:50 pm

1 stop7h 20m

$202

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 4/17

8:31 pm-1:00 pm

1 stop17h 29m

Chicago Midway

Tue 4/21

7:30 am-8:44 am

1 stop24h 14m

$205

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

8:43 pm-1:00 pm

1 stop17h 17m

Chicago Midway

Tue 4/28

7:30 am-7:04 pm

1 stop10h 34m

$217

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

8:31 pm-1:00 pm

1 stop17h 29m

Chicago Midway

Sat 4/25

7:30 am-11:29 pm

2 stops14h 59m

$220

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

11:15 am-3:45 pm

2 stops5h 30m

Chicago Midway

Tue 4/28

9:50 am-5:35 pm

1 stop6h 45m

$222
Quickest round-trip

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

11:15 am-3:45 pm

2 stops5h 30m

Chicago Midway

Tue 4/28

7:50 am-3:25 pm

2 stops6h 35m

$227

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 4/17

8:31 pm-1:00 pm

1 stop17h 29m

Chicago Midway

Tue 4/21

6:10 am-4:31 pm

2 stops9h 21m

$240

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 4/21

11:15 am-3:45 pm

2 stops5h 30m

Chicago Midway

Sat 4/25

10:15 am-8:45 pm

2 stops9h 30m

$264

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 4/24

8:43 pm-1:00 pm

1 stop17h 17m

Chicago Midway

Sun 4/26

7:30 am-7:04 pm

1 stop10h 34m

$273

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Thu 4/23

11:52 am-10:19 pm

2 stops11h 27m

Chicago Midway

Sun 4/26

7:30 am-7:04 pm

1 stop10h 34m

$276

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Wednesday is the cheapest day to fly to Chicago Midway Airport from Myrtle Beach. The lowest ticket price found for a Wednesday departure recently was $362. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Sunday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $468.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Myrtle Beach in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $422 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $433. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Myrtle Beach Intl to Chicago Midway flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago Midway flight prices

What cabin class options are available on Myrtle Beach Intl to Chicago Midway flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago Midway Airport flights?

You could potentially save up to 30% on your flight if you consider stops on a Myrtle Beach to Chicago Midway Airport flight.

When to book flights from Myrtle Beach to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago Midway Airport (MYR to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago Midway Airport

Best Price Found

$227

Fastest flight time

2h 05m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun
The best one-way flight to Chicago Midway Airport from Myrtle Beach in the past 72 hours is $227. The best round-trip flight deal from Myrtle Beach to Chicago Midway Airport found on momondo in the last 72 hours is $395.
The fastest flight from Myrtle Beach to Chicago Midway Airport takes 2h 05m
Direct flights go from Myrtle Beach to Chicago Midway Airport on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Southwest.
Search flight deals

  • How far is Myrtle Beach Intl to Chicago Midway by plane?

    The distance between Myrtle Beach Intl and Chicago Midway is about 738.5 mi. By plane, this route typically takes 2h 05m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Prices for flights from Myrtle Beach Intl Airport to Chicago Midway Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago Midway Airport?

  • What is the most popular airline from Myrtle Beach to Chicago Midway Airport?

Best airlines flying from Myrtle Beach to Chicago Midway Airport

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $239Free CancellationRating
8.0
4,324 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago Midway Airport

    Southwest operates around 3 flights from Myrtle Beach to Chicago Midway Airport every week. The average price of these flights found in the last 72 hours has been $389, but momondo users have found Southwest deals from Myrtle Beach to Chicago Midway Airport from as low as $239 round-trip. Southwest has been scored 8.0/10 in 4,324 reviews.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Chicago.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Myrtle Beach and alert you when they change.

An easier way to manage your Chicago Midway Airport trip

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