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Cheap flights from Myrtle Beach to the Dominican Republic from $332

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to the Dominican Republic departing on 8/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to the Dominican Republic

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:30 am - 6:34 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
11h 04m2 stops Philadelphia Miami
American Airlines Logo
7:34 pm - 1:26 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
17h 52m2 stops Miami Charlotte Douglas
$555American Airlines
Fri, Sep 18 - Fri, Sep 25
American Airlines Logo
7:10 pm - 1:11 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
18h 01m2 stops Washington, D.C. Reagan-National Miami
American Airlines Logo
9:30 am - 6:45 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
9h 15m2 stops Miami Charlotte Douglas
$555American Airlines
Tue, Sep 15 - Tue, Sep 22
American Airlines Logo
7:20 pm - 1:00 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
17h 40m1 stop Philadelphia
American Airlines Logo
7:34 pm - 11:37 amSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
16h 03m2 stops Miami Washington, D.C. Reagan-National
$560American Airlines
Wed, Sep 2 - Wed, Sep 9
American Airlines Logo
6:15 am - 6:44 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
12h 29m2 stops Charlotte Douglas Miami
American Airlines Logo
7:34 pm - 11:20 amSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
15h 46m2 stops Miami Charlotte Douglas
$560American Airlines
Wed, Sep 2 - Wed, Sep 9
American Airlines Logo
5:00 am - 8:50 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
15h 50m2 stops Charlotte Douglas Miami
American Airlines Logo
7:00 am - 10:29 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
16h 29m2 stops Miami Charlotte Douglas
$563American Airlines
Fri, Oct 30 - Tue, Nov 10
American Airlines Logo
5:00 am - 8:50 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
15h 50m2 stops Charlotte Douglas Miami
American Airlines Logo
7:00 am - 10:29 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
16h 29m2 stops Miami Charlotte Douglas
$564American Airlines
Fri, Oct 30 - Tue, Nov 10
American Airlines Logo
5:00 am - 8:50 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
15h 50m2 stops Charlotte Douglas Miami
American Airlines Logo
7:00 am - 10:29 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
16h 29m2 stops Miami Charlotte Douglas
$565American Airlines
Fri, Oct 30 - Tue, Nov 10
American Airlines Logo
5:00 am - 8:50 pmMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
15h 50m2 stops Charlotte Douglas Miami
American Airlines Logo
7:00 am - 10:29 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
16h 29m2 stops Miami Charlotte Douglas
$567American Airlines
Fri, Oct 30 - Tue, Nov 10
United Airlines Logo
6:59 pm - 11:55 amMYR  Myrtle Beach Intl-SDQ Santo Domingo Las Americas
16h 56m1 stop Newark
United Airlines Logo
6:00 am - 6:18 pmSDQ  Santo Domingo Las Americas-MYR Myrtle Beach Intl
12h 18m1 stop Newark
$577United Airlines
Tue, Sep 15 - Tue, Sep 22
Delta Logo
6:00 am - 4:42 pmMYR  Myrtle Beach Intl-PUJ Punta Cana
9h 42m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:55 pm - 11:35 pmPUJ  Punta Cana-MYR Myrtle Beach Intl
7h 40m1 stop Atlanta Hartsfield-Jackson
$626Delta
Sun, Jan 10 - Wed, Feb 10

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American Airlines flights from Myrtle Beach to Dominican Republic

Our best American Airlines deals on Myrtle Beach to Dominican Republic flight tickets
American Airlines
Sep 18
MYR7:30 amMyrtle Beach Intl
11h 04m
2 stops
SDQ6:34 pmSanto Domingo Las Americas
Sep 25
SDQ7:34 pmSanto Domingo Las Americas
17h 52m
2 stops
MYR1:26 pmMyrtle Beach Intl
$555
American Airlines
Sep 2
MYR6:15 amMyrtle Beach Intl
12h 29m
2 stops
SDQ6:44 pmSanto Domingo Las Americas
Sep 9
SDQ7:34 pmSanto Domingo Las Americas
15h 46m
2 stops
MYR11:20 amMyrtle Beach Intl
$560
American Airlines
Oct 30
MYR5:00 amMyrtle Beach Intl
15h 50m
2 stops
SDQ8:50 pmSanto Domingo Las Americas
Nov 10
SDQ7:00 amSanto Domingo Las Americas
16h 29m
2 stops
MYR10:29 pmMyrtle Beach Intl
$563

Frontier flights from Myrtle Beach to Dominican Republic

Our best Frontier deals on Myrtle Beach to Dominican Republic flight tickets
Frontier
Aug 13
MYR3:49 pmMyrtle Beach Intl
46h 32m
2 stops
PUJ2:21 pmPunta Cana
Aug 16
PUJ9:29 pmPunta Cana
38h 14m
2 stops
MYR11:43 amMyrtle Beach Intl
$1,049
Frontier
Aug 9
MYR3:49 pmMyrtle Beach Intl
46h 32m
2 stops
PUJ2:21 pmPunta Cana
Aug 16
PUJ9:29 pmPunta Cana
38h 14m
2 stops
MYR11:43 amMyrtle Beach Intl
$1,051
Frontier
Aug 9
MYR6:23 pmMyrtle Beach Intl
16h 19m
1 stop
PUJ10:42 amPunta Cana
Aug 16
PUJ9:29 pmPunta Cana
38h 14m
2 stops
MYR11:43 amMyrtle Beach Intl
$1,079

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Dominican Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to the Dominican Republic that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Fri 9/18

7:30 am-6:34 pm

2 stops11h 04m

Santo Domingo Las Americas

Fri 9/25

7:34 pm-1:26 pm

2 stops17h 52m

$555

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Tue 9/15

7:10 pm-1:11 pm

2 stops18h 01m

Santo Domingo Las Americas

Tue 9/22

9:30 am-6:45 pm

2 stops9h 15m

$555

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Wed 9/2

7:20 pm-1:00 pm

1 stop17h 40m

Santo Domingo Las Americas

Wed 9/9

7:34 pm-11:37 am

2 stops16h 03m

$560

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Wed 9/2

6:15 am-6:44 pm

2 stops12h 29m

Santo Domingo Las Americas

Wed 9/9

7:34 pm-11:20 am

2 stops15h 46m

$560

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Fri 10/30

5:00 am-8:50 pm

2 stops15h 50m

Santo Domingo Las Americas

Tue 11/10

7:00 am-10:29 pm

2 stops16h 29m

$563

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Fri 10/30

5:00 am-8:50 pm

2 stops15h 50m

Santo Domingo Las Americas

Tue 11/10

7:00 am-10:29 pm

2 stops16h 29m

$564

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Fri 10/30

5:00 am-8:50 pm

2 stops15h 50m

Santo Domingo Las Americas

Tue 11/10

7:00 am-10:29 pm

2 stops16h 29m

$565

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Fri 10/30

5:00 am-8:50 pm

2 stops15h 50m

Santo Domingo Las Americas

Tue 11/10

7:00 am-10:29 pm

2 stops16h 29m

$567

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Tue 9/15

6:59 pm-11:55 am

1 stop16h 56m

Santo Domingo Las Americas

Tue 9/22

6:00 am-6:18 pm

1 stop12h 18m

$577
Quickest round-trip

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Sun 1/10

6:00 am-4:42 pm

1 stop9h 42m

Punta Cana

Wed 2/10

4:55 pm-11:35 pm

1 stop7h 40m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to the Dominican Republic from

How to get the cheapest flight ticket from Myrtle Beach to Dominican Republic

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Dominican Republic?

In general, November is the cheapest month to fly from Myrtle Beach to Dominican Republic. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $527. If you are unable to visit Dominican Republic during the month of November, then departing from Myrtle Beach during the month January is also very affordable. Most momondo users find prices during this month for around $544.

Can stopping save me money on Myrtle Beach to Dominican Republic flights?

You could potentially save up to 30% on your flight if you consider stops on a Myrtle Beach to Dominican Republic flight.

Cheap Myrtle Beach to Dominican Republic flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Dominican Republic

Fastest flight time

5h 43m

Direct flights

None
The fastest flight from Myrtle Beach to Dominican Republic takes 5h 43m
There are no direct flights from Myrtle Beach to Dominican Republic. There are no popular flight routes from Myrtle Beach to Dominican Republic.
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Frequently asked questions about flying from Myrtle Beach to the Dominican Republic

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Dominican Republic?

    Prices for flights from Myrtle Beach Intl Airport to Dominican Republic are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Dominican Republic?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Dominican Republic?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Dominican Republic.

  • What documentation or ID do you need to fly to Dominican Republic?

    The necessary travel and health documents for your Dominican Republic trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Myrtle Beach to Dominican Republic

Compare and see reviews for airlines that fly from Myrtle Beach to Dominican Republic with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $500Free CancellationRating
7.1
11,867 reviews
Search American Airlines flights
SouthwestPriceFrom $667Free CancellationRating
8.0
4,218 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Dominican Republic?

It is quick and easy to find Myrtle Beach to Dominican Republic flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Dominican Republic that suits you.

Can I find flights from Myrtle Beach to Dominican Republic with flexible booking policies on momondo?

Yes. All flights to Dominican Republic from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to Dominican Republic?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Dominican Republic from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to Dominican Republic right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to Dominican Republic flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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