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Cheap flights from Missouri to Central America from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Central America departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Central America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
11:26 am - 12:22 pm
MCI
-
SJO
24h 56m1 stop
Spirit Airlines Logo
1:30 pm - 10:31 am
SJO
-
MCI
21h 01m1 stop
$304Spirit Airlines
Sun, Jan 18 - Thu, Jan 22
Spirit Airlines Logo
11:26 am - 12:22 pm
MCI
-
SJO
24h 56m1 stop
Spirit Airlines Logo
1:30 pm - 10:31 am
SJO
-
MCI
21h 01m1 stop
$309Spirit Airlines
Mon, Jan 12 - Thu, Jan 22
Multiple Airlines Logo
5:42 pm - 11:37 am
STL
-
SJO
17h 55m1 stop
Multiple Airlines Logo
12:33 pm - 11:33 pm
SJO
-
STL
11h 00m1 stop
$311Multiple Airlines
Mon, Jan 26 - Fri, Jan 30
Multiple Airlines Logo
5:42 pm - 11:37 am
STL
-
SJO
17h 55m1 stop
Multiple Airlines Logo
12:33 pm - 10:23 am
SJO
-
STL
21h 50m1 stop
$312Multiple Airlines
Mon, Jan 26 - Thu, Jan 29
Multiple Airlines Logo
8:22 pm - 12:22 pm
STL
-
SJO
16h 00m2 stops
Multiple Airlines Logo
12:33 pm - 10:23 am
SJO
-
STL
21h 50m1 stop
$313Multiple Airlines
Fri, Jan 23 - Thu, Jan 29
United Airlines Logo
6:00 am - 1:10 pm
STL
-
LIR
7h 10m1 stop
United Airlines Logo
8:35 am - 10:00 pm
LIR
-
STL
13h 25m1 stop
$321United Airlines
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
5:59 pm - 2:13 pm
STL
-
LIR
20h 14m2 stops
American Airlines Logo
3:13 pm - 9:40 am
LIR
-
STL
18h 27m2 stops
$325American Airlines
Tue, Jan 20 - Tue, Jan 27
Frontier Logo
3:43 pm - 1:36 pm
STL
-
SJO
21h 53m1 stop
Frontier Logo
2:58 pm - 10:34 pm
SJO
-
STL
31h 36m2 stops
$325Frontier
Thu, Jan 8 - Mon, Jan 12
American Airlines Logo
5:04 pm - 12:22 pm
STL
-
BZE
19h 18m2 stops
American Airlines Logo
4:16 pm - 9:40 am
BZE
-
STL
17h 24m2 stops
$339American Airlines
Sat, Jan 24 - Fri, Jan 30
United Airlines Logo
6:00 am - 5:07 pm
STL
-
PTY
10h 07m1 stop
United Airlines Logo
4:41 pm - 9:23 am
PTY
-
STL
17h 42m1 stop
$394United Airlines
Tue, Feb 17 - Wed, Feb 25

Spirit Airlines flights from Missouri to Central America

Our best Spirit Airlines deals on Missouri to Central America flight tickets
Spirit Airlines
Jan 18
MCI11:26 amKansas City
24h 56m
1 stop
SJO12:22 pmSan José Juan Santamaria Intl
Jan 22
SJO1:30 pmSan José Juan Santamaria Intl
21h 01m
1 stop
MCI10:31 amKansas City
$304
Find similar
Spirit Airlines
Jan 12
MCI11:26 amKansas City
24h 56m
1 stop
SJO12:22 pmSan José Juan Santamaria Intl
Jan 22
SJO1:30 pmSan José Juan Santamaria Intl
21h 01m
1 stop
MCI10:31 amKansas City
$309
Find similar
Spirit Airlines
Jan 18
MCI11:26 amKansas City
24h 11m
2 stops
SJO11:37 amSan José Juan Santamaria Intl
Jan 22
SJO1:30 pmSan José Juan Santamaria Intl
21h 01m
1 stop
MCI10:31 amKansas City
$319
Find similar

Frontier flights from Missouri to Central America

Our best Frontier deals on Missouri to Central America flight tickets
Frontier
Jan 8
STL3:43 pmLambert-St Louis
21h 53m
1 stop
SJO1:36 pmSan José Juan Santamaria Intl
Jan 12
SJO2:58 pmSan José Juan Santamaria Intl
31h 36m
2 stops
STL10:34 pmLambert-St Louis
$325
Find similar
Frontier
Dec 19
STL8:37 pmLambert-St Louis
12h 44m
1 stop
SJO9:21 amSan José Juan Santamaria Intl
Dec 24
SJO2:52 pmSan José Juan Santamaria Intl
18h 48m
1 stop
STL9:40 amLambert-St Louis
$472
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Sun 1/18

11:26 am-12:22 pm

1 stop24h 56m

San José Juan Santamaria Intl

Thu 1/22

1:30 pm-10:31 am

1 stop21h 01m

$304

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Mon 1/12

11:26 am-12:22 pm

1 stop24h 56m

San José Juan Santamaria Intl

Thu 1/22

1:30 pm-10:31 am

1 stop21h 01m

$309

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Mon 1/26

5:42 pm-11:37 am

1 stop17h 55m

San José Juan Santamaria Intl

Fri 1/30

12:33 pm-11:33 pm

1 stop11h 00m

$311

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Mon 1/26

5:42 pm-11:37 am

1 stop17h 55m

San José Juan Santamaria Intl

Thu 1/29

12:33 pm-10:23 am

1 stop21h 50m

$312

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Fri 1/23

8:22 pm-12:22 pm

2 stops16h 00m

San José Juan Santamaria Intl

Thu 1/29

12:33 pm-10:23 am

1 stop21h 50m

$313

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Tue 1/20

6:00 am-1:10 pm

1 stop7h 10m

Liberia

Tue 1/27

8:35 am-10:00 pm

1 stop13h 25m

$321

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Tue 1/20

5:59 pm-2:13 pm

2 stops20h 14m

Liberia

Tue 1/27

3:13 pm-9:40 am

2 stops18h 27m

$325

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Thu 1/8

3:43 pm-1:36 pm

1 stop21h 53m

San José Juan Santamaria Intl

Mon 1/12

2:58 pm-10:34 pm

2 stops31h 36m

$325

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Sat 1/24

5:04 pm-12:22 pm

2 stops19h 18m

Belize City Philip S.W.Goldson

Fri 1/30

4:16 pm-9:40 am

2 stops17h 24m

$339

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 2/17

6:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Wed 2/25

4:41 pm-9:23 am

1 stop17h 42m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, October is the cheapest month to fly from Missouri to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $417. If you don’t want to visit Central America in October, then you should wait until September to fly from Missouri, when ticket prices are also cheap, with an average price of $435.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Missouri to Central America is on a Tuesday. Travelers who choose to depart for Central America on a Tuesday will often find tickets for as low as $474. On the other hand, Sunday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $623.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Missouri to Central America flights are usually those with departure times in the evening. Our users have found flights to Central America in the evening for as low as $499. Try not to purchase tickets at noon because they tend to be around $639. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Missouri to Central America flight route?

Fly from Lambert-St Louis to Belize City Philip S.W.Goldson for the best Missouri - Central America flight prices

How far in advance should I book a flight to Central America?

You are more likely to see cheaper flights to Central America from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Central America for around $589 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Central America from Missouri for as low as $444 on momondo.

What cabin class options are available on Missouri to Central America flights?

There is only 1 cabin class available to choose from on Missouri to Central America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Central America flights?

You could potentially save up to 29% on your flight if you consider stops on a Missouri to Central America flight.

Cheap Missouri to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Central America

Fastest flight time

5h 35m

Direct flights

None
The fastest flight from Missouri to Central America takes 5h 35m
There are no direct flights from Missouri to Central America. There are no popular flight routes from Missouri to Central America.
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  • When did momondo last update prices for flights from Missouri to Central America?

    Prices for flights from Missouri to Central America are updated daily.

  • How many operators does momondo search for flights from Missouri to Central America?

  • How old do you have to be to fly from Missouri to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Central America

Compare and see reviews for airlines that fly from Missouri to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $218Free CancellationRating
7.9
8,007 reviews
Search Delta flights
Spirit AirlinesPriceFrom $270Free CancellationRating
6.3
8,185 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $287Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
American AirlinesPriceFrom $319Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
SouthwestPriceFrom $366Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Central America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Central America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Central America with flexible booking policies on momondo?

All flight searches from Missouri to Central America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Central America?

Once all potential Missouri to Central America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Central America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Central America from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
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