Cheap flights from Missouri to Central America from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Central America departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
4:17 pm - 8:20 am
STL
-
SJO
17h 03m
1 stop
Frontier Logo
9:35 am - 11:59 pm
SJO
-
STL
13h 24m
1 stop
$362Frontier
Sat, Jun 20 - Sat, Jul 11
Frontier Logo
4:17 pm - 8:20 am
STL
-
SJO
17h 03m
1 stop
Frontier Logo
9:35 am - 5:37 pm
SJO
-
STL
31h 02m
2 stops
$423Frontier
Sat, Jun 20 - Sat, Jul 11
United Airlines Logo
6:23 am - 2:30 pm
MCI
-
SAL
9h 07m
1 stop
United Airlines Logo
3:40 pm - 9:07 am
SAL
-
MCI
16h 27m
2 stops
$435United Airlines
Wed, Sep 9 - Mon, Sep 14
United Airlines Logo
6:23 am - 12:15 pm
MCI
-
SAL
6h 52m
1 stop
United Airlines Logo
3:40 pm - 10:05 am
SAL
-
MCI
17h 25m
1 stop
$440United Airlines
Wed, Sep 9 - Mon, Sep 14
Air Canada Logo
7:05 am - 12:05 pm
STL
-
LIR
30h 00m
1 stop
Air Canada Logo
1:00 pm - 12:06 pm
LIR
-
STL
22h 06m
1 stop
$458Air Canada
Fri, May 29 - Sat, Jun 6
Air Canada Logo
1:05 pm - 12:05 pm
STL
-
LIR
24h 00m
2 stops
Air Canada Logo
1:00 pm - 12:06 pm
LIR
-
STL
22h 06m
1 stop
$461Air Canada
Fri, May 29 - Sat, Jun 6
Delta Logo
3:36 pm - 12:56 pm
MCI
-
PTY
21h 20m
1 stop
Delta Logo
2:21 pm - 10:26 pm
PTY
-
MCI
8h 05m
1 stop
$475Delta
Mon, Oct 19 - Thu, Oct 29
American Airlines Logo
5:29 am - 2:40 pm
STL
-
LIR
10h 11m
1 stop
American Airlines Logo
3:40 pm - 8:47 am
LIR
-
STL
16h 07m
1 stop
$492American Airlines
Mon, Jul 20 - Thu, Jul 23
American Airlines Logo
7:56 pm - 1:15 pm
STL
-
LIR
18h 19m
2 stops
American Airlines Logo
2:47 pm - 11:55 am
LIR
-
STL
20h 08m
2 stops
$497American Airlines
Mon, Jul 20 - Thu, Jul 23
Delta Logo
5:40 am - 11:54 am
MCI
-
SJO
7h 14m
1 stop
Delta Logo
1:25 pm - 11:52 pm
SJO
-
MCI
9h 27m
1 stop
$510Delta
Tue, Sep 22 - Fri, Oct 2

American Airlines flights from Missouri to Central America

Our best American Airlines deals on Missouri to Central America flight tickets
American Airlines
Jul 20
STL5:29 amLambert-St Louis
10h 11m
1 stop
LIR2:40 pmLiberia
Jul 23
LIR3:40 pmLiberia
16h 07m
1 stop
STL8:47 amLambert-St Louis
$492
American Airlines
Jul 20
STL7:56 pmLambert-St Louis
18h 19m
2 stops
LIR1:15 pmLiberia
Jul 23
LIR2:47 pmLiberia
20h 08m
2 stops
STL11:55 amLambert-St Louis
$497
American Airlines
Sep 23
MCI5:46 amKansas City
13h 44m
2 stops
SJO6:30 pmSan José Juan Santamaria Intl
Oct 7
SJO2:45 pmSan José Juan Santamaria Intl
18h 34m
2 stops
MCI10:19 amKansas City
$515

Delta flights from Missouri to Central America

Our best Delta deals on Missouri to Central America flight tickets
Delta
Oct 21
MCI5:40 amKansas City
7h 16m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 29
PTY2:21 pmPanama City Tocumen Intl
9h 37m
1 stop
MCI11:58 pmKansas City
$467
Delta
Oct 19
MCI6:42 pmKansas City
18h 14m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 27
PTY2:21 pmPanama City Tocumen Intl
8h 05m
1 stop
MCI10:26 pmKansas City
$475
Delta
Sep 22
MCI5:40 amKansas City
7h 14m
1 stop
SJO11:54 amSan José Juan Santamaria Intl
Oct 2
SJO1:25 pmSan José Juan Santamaria Intl
9h 27m
1 stop
MCI11:52 pmKansas City
$510

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sat 6/20

4:17 pm-8:20 am

1 stop17h 03m

San José Juan Santamaria Intl

Sat 7/11

9:35 am-11:59 pm

1 stop13h 24m

$362

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Sat 6/20

4:17 pm-8:20 am

1 stop17h 03m

San José Juan Santamaria Intl

Sat 7/11

9:35 am-5:37 pm

2 stops31h 02m

$423

Kansas CitySan Salvador

MCI - SAL

MCISAL

Kansas City

Wed 9/9

6:23 am-2:30 pm

1 stop9h 07m

San Salvador El Salvador Intl

Mon 9/14

3:40 pm-9:07 am

2 stops16h 27m

$435

Kansas CitySan Salvador

MCI - SAL

MCISAL

Kansas City

Wed 9/9

6:23 am-12:15 pm

1 stop6h 52m

San Salvador El Salvador Intl

Mon 9/14

3:40 pm-10:05 am

1 stop17h 25m

$440

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Fri 5/29

7:05 am-12:05 pm

1 stop30h 00m

Liberia

Sat 6/6

1:00 pm-12:06 pm

1 stop22h 06m

$458

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Fri 5/29

1:05 pm-12:05 pm

2 stops24h 00m

Liberia

Sat 6/6

1:00 pm-12:06 pm

1 stop22h 06m

$461

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Mon 10/19

3:36 pm-12:56 pm

1 stop21h 20m

Panama City Tocumen Intl

Thu 10/29

2:21 pm-10:26 pm

1 stop8h 05m

$475

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 7/20

5:29 am-2:40 pm

1 stop10h 11m

Liberia

Thu 7/23

3:40 pm-8:47 am

1 stop16h 07m

$492

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 7/20

7:56 pm-1:15 pm

2 stops18h 19m

Liberia

Thu 7/23

2:47 pm-11:55 am

2 stops20h 08m

$497
Quickest round-trip

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Tue 9/22

5:40 am-11:54 am

1 stop7h 14m

San José Juan Santamaria Intl

Fri 10/2

1:25 pm-11:52 pm

1 stop9h 27m

$510

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, August is the cheapest month to fly from Missouri to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $131. If you don’t want to visit Central America in August, then you should wait until October to fly from Missouri, when ticket prices are also cheap, with an average price of $157.

Can stopping save me money on Missouri to Central America flights?

You could potentially save up to 23% on your flight if you consider stops on a Missouri to Central America flight.

Cheap Missouri to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Central America

Fastest flight time

5h 30m

Direct flights

None
The fastest flight from Missouri to Central America takes 5h 30m
There are no direct flights from Missouri to Central America. There are no popular flight routes from Missouri to Central America.

Frequently asked questions about flying from Missouri to Central America

  • When did momondo last update prices for flights from Missouri to Central America?

    Prices for flights from Missouri to Central America are updated daily.

  • How many operators does momondo search for flights from Missouri to Central America?

  • How old do you have to be to fly from Missouri to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Missouri to Central America

Compare and see reviews for airlines that fly from Missouri to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $217Free CancellationRating
7.9
8,455 reviews
Search Delta flights
Spirit AirlinesPriceFrom $285Free CancellationRating
6.2
8,625 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $287Free CancellationRating
7.4
9,727 reviews
Search United Airlines flights
American AirlinesPriceFrom $314Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights
SouthwestPriceFrom $366Free CancellationRating
8.0
4,296 reviews
Search Southwest flights
GOLPriceFrom $644Free CancellationRating
7.3
1,219 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Central America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Missouri to Central America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Missouri to Central America with flexible booking policies on momondo?

All flight searches from Missouri to Central America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Missouri to Central America?

Once all potential Missouri to Central America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Central America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Central America from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Central America trip

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1 adult
Sun 6/14
Sun 6/21

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