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Cheap flights from Minneapolis to Santiago from $395

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Santiago departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Minneapolis to Santiago

Cheap round-trip flights

Logo
6:12 am - 2:45 pmMSP-SCL
30h 33m2 stops
Logo
9:05 pm - 11:27 pmSCL-MSP
28h 22m3 stops
$639
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Mon, Oct 20 - Fri, Oct 31
Logo
6:12 am - 2:45 pmMSP-SCL
30h 33m2 stops
Logo
12:30 pm - 3:00 pmSCL-MSP
28h 30m2 stops
$641
Find Deal
Mon, Oct 20 - Fri, Oct 31
LATAM Airlines Logo
12:50 pm - 7:00 amMSP-SCL
16h 10m1 stop
LATAM Airlines Logo
10:40 pm - 1:42 pmSCL-MSP
17h 02m1 stop
$900LATAM Airlines
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Tue, Mar 10 - Fri, Mar 20
United Airlines Logo
6:00 am - 8:50 amMSP-SCL
23h 50m2 stops
United Airlines Logo
10:45 pm - 4:58 pmSCL-MSP
21h 13m1 stop
$914United Airlines
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Tue, Nov 11 - Wed, Nov 19
American Airlines Logo
6:30 am - 8:00 amMSP-SCL
23h 30m1 stop
American Airlines Logo
9:55 pm - 5:16 pmSCL-MSP
21h 21m2 stops
$918American Airlines
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Mon, Oct 13 - Mon, Oct 20
LATAM Airlines Logo
1:15 pm - 5:35 amMSP-SCL
13h 20m1 stop
LATAM Airlines Logo
9:30 pm - 9:14 amSCL-MSP
14h 44m1 stop
$922LATAM Airlines
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Thu, Dec 11 - Tue, Jan 20
American Airlines Logo
6:30 am - 8:00 amMSP-SCL
23h 30m1 stop
American Airlines Logo
9:55 pm - 10:59 pmSCL-MSP
27h 04m1 stop
$927American Airlines
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Mon, Oct 13 - Mon, Oct 20
United Airlines Logo
8:15 am - 8:50 amMSP-SCL
21h 35m2 stops
United Airlines Logo
9:45 pm - 5:01 pmSCL-MSP
21h 16m2 stops
$938United Airlines
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Tue, Mar 3 - Tue, Mar 17
Delta Logo
6:05 pm - 7:00 amMSP-SCL
33h 55m1 stop
Delta Logo
11:15 pm - 1:59 pmSCL-MSP
17h 44m1 stop
$974Delta
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Sat, Feb 7 - Fri, Feb 20
Delta Logo
8:15 pm - 7:00 amMSP-SCL
31h 45m1 stop
Delta Logo
11:25 pm - 5:22 pmSCL-MSP
20h 57m2 stops
$979Delta
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Fri, Feb 6 - Sun, Feb 22

Copa Airlines flights from Minneapolis to Santiago

Our best Copa Airlines deals on Minneapolis to Santiago flight tickets
Copa Airlines
Nov 19
MSP9:55 amMinneapolis St Paul
17h 06m
2 stops
SCL6:01 amSantiago Arturo Merino Benitez
Nov 28
SCL1:29 amSantiago Arturo Merino Benitez
18h 51m
2 stops
MSP5:20 pmMinneapolis St Paul
$986
Find similar
Copa Airlines
Sep 17
MSP10:00 amMinneapolis St Paul
17h 58m
2 stops
SCL5:58 amSantiago Arturo Merino Benitez
Sep 22
SCL3:26 amSantiago Arturo Merino Benitez
33h 02m
2 stops
MSP10:28 amMinneapolis St Paul
$1,456
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LATAM Airlines flights from Minneapolis to Santiago

Our best LATAM Airlines deals on Minneapolis to Santiago flight tickets
LATAM Airlines
Mar 10
MSP12:50 pmMinneapolis St Paul
16h 10m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Mar 20
SCL10:40 pmSantiago Arturo Merino Benitez
17h 02m
1 stop
MSP1:42 pmMinneapolis St Paul
$900
Find similar
LATAM Airlines
Dec 11
MSP1:15 pmMinneapolis St Paul
13h 20m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
Jan 20
SCL9:30 pmSantiago Arturo Merino Benitez
14h 44m
1 stop
MSP9:14 amMinneapolis St Paul
$922
Find similar
LATAM Airlines
Mar 5
MSP8:50 amMinneapolis St Paul
17h 45m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
Mar 15
SCL10:40 pmSantiago Arturo Merino Benitez
17h 02m
1 stop
MSP1:42 pmMinneapolis St Paul
$940
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/20

6:12 am-2:45 pm

2 stops30h 33m

Santiago Arturo Merino Benitez

Fri 10/31

9:05 pm-11:27 pm

3 stops28h 22m

$639

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/20

6:12 am-2:45 pm

2 stops30h 33m

Santiago Arturo Merino Benitez

Fri 10/31

12:30 pm-3:00 pm

2 stops28h 30m

$641

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 3/10

12:50 pm-7:00 am

1 stop16h 10m

Santiago Arturo Merino Benitez

Fri 3/20

10:40 pm-1:42 pm

1 stop17h 02m

$900

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 11/11

6:00 am-8:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Wed 11/19

10:45 pm-4:58 pm

1 stop21h 13m

$914

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/13

6:30 am-8:00 am

1 stop23h 30m

Santiago Arturo Merino Benitez

Mon 10/20

9:55 pm-5:16 pm

2 stops21h 21m

$918

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 12/11

1:15 pm-5:35 am

1 stop13h 20m

Santiago Arturo Merino Benitez

Tue 1/20

9:30 pm-9:14 am

1 stop14h 44m

$922

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/13

6:30 am-8:00 am

1 stop23h 30m

Santiago Arturo Merino Benitez

Mon 10/20

9:55 pm-10:59 pm

1 stop27h 04m

$927

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 3/3

8:15 am-8:50 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Tue 3/17

9:45 pm-5:01 pm

2 stops21h 16m

$938

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sat 2/7

6:05 pm-7:00 am

1 stop33h 55m

Santiago Arturo Merino Benitez

Fri 2/20

11:15 pm-1:59 pm

1 stop17h 44m

$974

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 2/6

8:15 pm-7:00 am

1 stop31h 45m

Santiago Arturo Merino Benitez

Sun 2/22

11:25 pm-5:22 pm

2 stops20h 57m

$979

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Minneapolis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Minneapolis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $933. If you don’t want to visit Santiago in October, then you should wait until January to fly from Minneapolis, when ticket prices are also cheap, with an average price of $948.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $913. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $1,238.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Minneapolis to Santiago when you can find flight prices for as low as $737. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,125 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,071 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Minneapolis for as low as $875 on momondo.

When to book flights from Minneapolis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Santiago (MSP to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Santiago

Direct flights

None
There are no direct flights from Minneapolis to Santiago. There are no popular flight routes from Minneapolis to Santiago.
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  • How far is Minneapolis St Paul to Santiago Arturo Merino Benitez by plane?

    A flight from Minneapolis St Paul to Santiago Arturo Merino Benitez will travel around 5597.4 mi. Flights usually cover this in 13h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Minneapolis St Paul Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Minneapolis to Santiago?

Best airlines flying from Minneapolis to Santiago

Compare and see reviews for airlines that fly from Minneapolis to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $745Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $815Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $853Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
DeltaPriceFrom $853Free CancellationRating
7.9
7,954 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Minneapolis to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Minneapolis to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Minneapolis with this policy.

How can momondo help me find flights from Minneapolis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Minneapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Minneapolis to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Minneapolis are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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