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Cheap flights from Manchester to Des Moines from $466

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Des Moines departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Manchester to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:35 am - 9:23 pm
MAN
-
DSM
16h 48m
2 stops
United Airlines Logo
5:00 am - 9:50 am
DSM
-
MAN
22h 50m
2 stops
$1,258United Airlines
Mon, May 4 - Mon, May 11
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
1:48 pm - 1:55 pm
DSM
-
MAN
18h 07m
2 stops
$1,299Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
1:48 pm - 1:55 pm
DSM
-
MAN
18h 07m
2 stops
$1,302Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
1:46 pm - 1:55 pm
DSM
-
MAN
18h 09m
2 stops
$1,313Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
8:55 pm - 7:32 pm
MAN
-
DSM
28h 37m
2 stops
Multiple Airlines Logo
5:15 am - 8:40 am
DSM
-
MAN
21h 25m
2 stops
$1,320Multiple Airlines
Mon, Jun 1 - Mon, Jun 15
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
5:15 am - 8:40 am
DSM
-
MAN
21h 25m
2 stops
$1,322Multiple Airlines
Mon, Jun 1 - Mon, Jun 15
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
5:15 am - 7:40 am
DSM
-
MAN
20h 25m
2 stops
$1,323Multiple Airlines
Mon, Jun 1 - Mon, Jun 15
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
5:15 am - 8:40 am
DSM
-
MAN
21h 25m
2 stops
$1,326Multiple Airlines
Mon, Jun 1 - Mon, Jun 15
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
1:48 pm - 1:55 pm
DSM
-
MAN
18h 07m
2 stops
$1,330Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
8:55 pm - 6:36 pm
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
1:46 pm - 1:55 pm
DSM
-
MAN
18h 09m
2 stops
$1,334Multiple Airlines
Tue, Jun 2 - Tue, Jun 16

United Airlines flights from Manchester to Des Moines

Our best United Airlines deals on Manchester to Des Moines flight tickets
United Airlines
May 4
MAN10:35 amManchester
16h 48m
2 stops
DSM9:23 pmDes Moines
May 11
DSM5:00 amDes Moines
22h 50m
2 stops
MAN9:50 amManchester
$1,258
United Airlines
May 2
MAN6:05 amManchester
19h 21m
2 stops
DSM7:26 pmDes Moines
May 9
DSM3:26 pmDes Moines
19h 54m
2 stops
MAN5:20 pmManchester
$1,340

Delta flights from Manchester to Des Moines

Our best Delta deals on Manchester to Des Moines flight tickets
Delta
Jun 2
MAN1:00 pmManchester
15h 32m
1 stop
DSM10:32 pmDes Moines
Jun 16
DSM2:15 pmDes Moines
12h 35m
1 stop
MAN8:50 amManchester
$1,484
Delta
Jun 1
MAN1:00 pmManchester
28h 08m
1 stop
DSM11:08 amDes Moines
Jun 15
DSM2:35 pmDes Moines
17h 25m
2 stops
MAN2:00 pmManchester
$1,489
Delta
Jun 1
MAN1:00 pmManchester
28h 08m
1 stop
DSM11:08 amDes Moines
Jun 15
DSM2:35 pmDes Moines
17h 25m
2 stops
MAN2:00 pmManchester
$1,490

momondo Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 5/4

10:35 am-9:23 pm

2 stops16h 48m

Des Moines

Mon 5/11

5:00 am-9:50 am

2 stops22h 50m

$1,258

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 6/2

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Tue 6/16

1:48 pm-1:55 pm

2 stops18h 07m

$1,299

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 6/2

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Tue 6/16

1:48 pm-1:55 pm

2 stops18h 07m

$1,302

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 6/2

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Tue 6/16

1:46 pm-1:55 pm

2 stops18h 09m

$1,313

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 6/1

8:55 pm-7:32 pm

2 stops28h 37m

Des Moines

Mon 6/15

5:15 am-8:40 am

2 stops21h 25m

$1,320

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 6/1

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Mon 6/15

5:15 am-8:40 am

2 stops21h 25m

$1,322

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 6/1

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Mon 6/15

5:15 am-7:40 am

2 stops20h 25m

$1,323

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 6/1

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Mon 6/15

5:15 am-8:40 am

2 stops21h 25m

$1,326

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 6/2

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Tue 6/16

1:48 pm-1:55 pm

2 stops18h 07m

$1,330

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 6/2

8:55 pm-6:36 pm

2 stops27h 41m

Des Moines

Tue 6/16

1:46 pm-1:55 pm

2 stops18h 09m

$1,334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then October is your next best option. Flight prices from Manchester to Des Moines during October average around $1,087.

When to book flights from Manchester to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester to Des Moines (MAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Des Moines

Fastest flight time

16h 48m

Direct flights

None
The fastest flight from Manchester to Des Moines takes 16h 48m
There are no direct flights from Manchester to Des Moines. There are no popular flight routes from Manchester to Des Moines.
Search flight deals

  • How far is Manchester to Des Moines by plane?

    A flight from Manchester to Des Moines will travel around 4038.6 mi. A reasonable flight in good conditions will take 16h 48m.

  • When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

    Prices for flights from Manchester Airport to Des Moines Airport refresh daily.

  • How old do you have to be to fly from Manchester Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Des Moines for you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Manchester with this policy.

How can momondo help me find flights from Manchester to Des Moines?

Once you have performed a search for Manchester to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Manchester and alert you when they change.

An easier way to manage your Des Moines trip

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