Cheap flights from Manchester, New Hampshire to Panama from $566

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Panama departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

United Airlines Logo
1:30 pm - 2:14 pmMHT-PTY
25h 44m2 stops
United Airlines Logo
3:30 pm - 3:02 pmPTY-MHT
46h 32m2 stops
$566United Airlines
Find Deal
Mon, Sep 22 - Thu, Sep 25
United Airlines Logo
9:40 am - 2:14 pmMHT-PTY
29h 34m2 stops
United Airlines Logo
10:00 am - 10:42 amPTY-MHT
23h 42m2 stops
$568United Airlines
Find Deal
Thu, Sep 18 - Sun, Sep 21
United Airlines Logo
1:30 pm - 2:14 pmMHT-PTY
25h 44m2 stops
United Airlines Logo
3:30 pm - 3:02 pmPTY-MHT
46h 32m2 stops
$612United Airlines
Find Deal
Mon, Sep 22 - Thu, Sep 25
American Airlines Logo
3:59 pm - 12:55 pmMHT-PTY
21h 56m2 stops
American Airlines Logo
3:31 pm - 12:08 pmPTY-MHT
19h 37m2 stops
$652American Airlines
Find Deal
Mon, Sep 22 - Thu, Sep 25
United Airlines Logo
7:26 pm - 5:07 pmMHT-PTY
21h 41m2 stops
United Airlines Logo
8:55 am - 11:59 pmPTY-MHT
15h 04m2 stops
$787United Airlines
Find Deal
Mon, Dec 29 - Thu, Jan 8
American Airlines Logo
5:25 pm - 1:20 pmMHT-PTY
19h 55m2 stops
American Airlines Logo
2:45 pm - 11:53 amPTY-MHT
21h 08m2 stops
$799American Airlines
Find Deal
Mon, Dec 29 - Wed, Jan 7
American Airlines Logo
5:25 pm - 1:20 pmMHT-PTY
19h 55m2 stops
American Airlines Logo
2:45 pm - 11:53 amPTY-MHT
21h 08m2 stops
$819American Airlines
Find Deal
Sat, Dec 27 - Thu, Jan 8
American Airlines Logo
5:25 pm - 1:20 pmMHT-PTY
19h 55m2 stops
American Airlines Logo
2:45 pm - 3:17 pmPTY-MHT
24h 32m2 stops
$901American Airlines
Find Deal
Mon, Dec 29 - Tue, Jan 6
American Airlines Logo
5:25 pm - 1:20 pmMHT-PTY
19h 55m2 stops
American Airlines Logo
2:45 pm - 3:17 pmPTY-MHT
24h 32m2 stops
$921American Airlines
Find Deal
Sat, Dec 27 - Tue, Jan 6
American Airlines Logo
4:22 pm - 1:20 pmMHT-PTY
20h 58m2 stops
American Airlines Logo
4:45 pm - 12:00 pmPTY-MHT
19h 15m2 stops
$1,092American Airlines
Find Deal
Sat, Dec 27 - Fri, Jan 2

United Airlines flights from Manchester, New Hampshire to Panama

Our best United Airlines deals on Manchester, New Hampshire to Panama flight tickets
United Airlines
Sep 22
MHT1:30 pmManchester
25h 44m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Sep 25
PTY3:30 pmPanama City Tocumen Intl
46h 32m
2 stops
MHT3:02 pmManchester
United Airlines
Sep 18
MHT9:40 amManchester
29h 34m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Sep 21
PTY10:00 amPanama City Tocumen Intl
23h 42m
2 stops
MHT10:42 amManchester
United Airlines
Sep 22
MHT1:30 pmManchester
25h 44m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Sep 25
PTY3:30 pmPanama City Tocumen Intl
46h 32m
2 stops
MHT3:02 pmManchester

American Airlines flights from Manchester, New Hampshire to Panama

Our best American Airlines deals on Manchester, New Hampshire to Panama flight tickets
American Airlines
Sep 22
MHT3:59 pmManchester
21h 56m
2 stops
PTY12:55 pmPanama City Tocumen Intl
Sep 25
PTY3:31 pmPanama City Tocumen Intl
19h 37m
2 stops
MHT12:08 pmManchester
American Airlines
Dec 29
MHT5:25 pmManchester
19h 55m
2 stops
PTY1:20 pmPanama City Tocumen Intl
Jan 7
PTY2:45 pmPanama City Tocumen Intl
21h 08m
2 stops
MHT11:53 amManchester
American Airlines
Dec 27
MHT5:25 pmManchester
19h 55m
2 stops
PTY1:20 pmPanama City Tocumen Intl
Jan 8
PTY2:45 pmPanama City Tocumen Intl
21h 08m
2 stops
MHT11:53 amManchester

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 9/22

1:30 pm-2:14 pm

2 stops25h 44m

Panama City Tocumen Intl

Thu 9/25

3:30 pm-3:02 pm

2 stops46h 32m

$566

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Thu 9/18

9:40 am-2:14 pm

2 stops29h 34m

Panama City Tocumen Intl

Sun 9/21

10:00 am-10:42 am

2 stops23h 42m

$568

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 9/22

1:30 pm-2:14 pm

2 stops25h 44m

Panama City Tocumen Intl

Thu 9/25

3:30 pm-3:02 pm

2 stops46h 32m

$612

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 9/22

3:59 pm-12:55 pm

2 stops21h 56m

Panama City Tocumen Intl

Thu 9/25

3:31 pm-12:08 pm

2 stops19h 37m

$652

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 12/29

7:26 pm-5:07 pm

2 stops21h 41m

Panama City Tocumen Intl

Thu 1/8

8:55 am-11:59 pm

2 stops15h 04m

$787

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 12/29

5:25 pm-1:20 pm

2 stops19h 55m

Panama City Tocumen Intl

Wed 1/7

2:45 pm-11:53 am

2 stops21h 08m

$799

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

5:25 pm-1:20 pm

2 stops19h 55m

Panama City Tocumen Intl

Thu 1/8

2:45 pm-11:53 am

2 stops21h 08m

$819

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 12/29

5:25 pm-1:20 pm

2 stops19h 55m

Panama City Tocumen Intl

Tue 1/6

2:45 pm-3:17 pm

2 stops24h 32m

$901

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

5:25 pm-1:20 pm

2 stops19h 55m

Panama City Tocumen Intl

Tue 1/6

2:45 pm-3:17 pm

2 stops24h 32m

$921

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

4:22 pm-1:20 pm

2 stops20h 58m

Panama City Tocumen Intl

Fri 1/2

4:45 pm-12:00 pm

2 stops19h 15m

$1,092

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Manchester, New Hampshire to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Panama?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama from Manchester, New Hampshire according to our data. Copa Airlines is the first choice among our users, with 85% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Manchester, New Hampshire to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Panama

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Panama. There are no popular flight routes from Manchester, New Hampshire to Panama.
  • When did momondo last update prices for flights from Manchester Airport to Panama?

    Prices for flights from Manchester Airport to Panama are refreshed on a daily basis.

  • How old do you have to be to fly from Manchester Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Manchester to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Manchester to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Tue 8/26
Tue 9/2

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