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Cheap flights from Manchester, New Hampshire to Panama from $369

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Panama departing on 12/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:34 pm - 2:14 pm
MHT
-
PTY
19h 40m2 stops
United Airlines Logo
3:30 pm - 6:59 pm
PTY
-
MHT
26h 29m2 stops
$522United Airlines
Mon, Apr 13 - Wed, Apr 15
United Airlines Logo
7:28 pm - 5:07 pm
MHT
-
PTY
21h 39m2 stops
United Airlines Logo
4:41 pm - 6:53 pm
PTY
-
MHT
26h 12m2 stops
$529United Airlines
Fri, Feb 13 - Mon, Feb 23
United Airlines Logo
2:17 pm - 2:45 pm
MHT
-
PTY
24h 28m2 stops
United Airlines Logo
4:41 pm - 6:51 pm
PTY
-
MHT
26h 10m2 stops
$653United Airlines
Thu, Jan 15 - Wed, Jan 21
United Airlines Logo
7:28 pm - 2:45 pm
MHT
-
PTY
19h 17m2 stops
United Airlines Logo
4:41 pm - 1:58 pm
PTY
-
MHT
21h 17m2 stops
$817United Airlines
Fri, Feb 13 - Sun, Feb 22
American Airlines Logo
5:30 am - 3:38 pm
MHT
-
PTY
10h 08m2 stops
American Airlines Logo
4:50 pm - 11:17 am
PTY
-
MHT
18h 27m3 stops
$2,280American Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
5:30 am - 3:52 pm
MHT
-
PTY
10h 22m2 stops
American Airlines Logo
4:50 pm - 11:17 am
PTY
-
MHT
18h 27m3 stops
$2,288American Airlines
Sat, Jan 10 - Sun, Jan 18
United Airlines Logo
7:34 pm - 6:13 am
MHT
-
PTY
11h 39m1 stop
United Airlines Logo
9:13 am - 6:59 pm
PTY
-
MHT
8h 46m1 stop
$5,308United Airlines
Mon, Apr 13 - Wed, Apr 15

United Airlines flights from Manchester, New Hampshire to Panama

Our best United Airlines deals on Manchester, New Hampshire to Panama flight tickets
United Airlines
Apr 13
MHT7:34 pmManchester
19h 40m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Apr 15
PTY3:30 pmPanama City Tocumen Intl
26h 29m
2 stops
MHT6:59 pmManchester
$522
Find similar
United Airlines
Feb 13
MHT7:28 pmManchester
21h 39m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Feb 23
PTY4:41 pmPanama City Tocumen Intl
26h 12m
2 stops
MHT6:53 pmManchester
$529
Find similar
United Airlines
Jan 15
MHT2:17 pmManchester
24h 28m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Jan 21
PTY4:41 pmPanama City Tocumen Intl
26h 10m
2 stops
MHT6:51 pmManchester
$653
Find similar

American Airlines flights from Manchester, New Hampshire to Panama

Our best American Airlines deals on Manchester, New Hampshire to Panama flight tickets
American Airlines
Jan 25
MHT5:30 amManchester
10h 08m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Feb 1
PTY4:50 pmPanama City Tocumen Intl
18h 27m
3 stops
MHT11:17 amManchester
$2,280
Find similar
American Airlines
Jan 10
MHT5:30 amManchester
10h 22m
2 stops
PTY3:52 pmPanama City Tocumen Intl
Jan 18
PTY4:50 pmPanama City Tocumen Intl
18h 27m
3 stops
MHT11:17 amManchester
$2,288
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 4/13

7:34 pm-2:14 pm

2 stops19h 40m

Panama City Tocumen Intl

Wed 4/15

3:30 pm-6:59 pm

2 stops26h 29m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 2/13

7:28 pm-5:07 pm

2 stops21h 39m

Panama City Tocumen Intl

Mon 2/23

4:41 pm-6:53 pm

2 stops26h 12m

$529

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Thu 1/15

2:17 pm-2:45 pm

2 stops24h 28m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-6:51 pm

2 stops26h 10m

$653

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 2/13

7:28 pm-2:45 pm

2 stops19h 17m

Panama City Tocumen Intl

Sun 2/22

4:41 pm-1:58 pm

2 stops21h 17m

$817

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sun 1/25

5:30 am-3:38 pm

2 stops10h 08m

Panama City Tocumen Intl

Sun 2/1

4:50 pm-11:17 am

3 stops18h 27m

$2,280

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 1/10

5:30 am-3:52 pm

2 stops10h 22m

Panama City Tocumen Intl

Sun 1/18

4:50 pm-11:17 am

3 stops18h 27m

$2,288

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 4/13

7:34 pm-6:13 am

1 stop11h 39m

Panama City Tocumen Intl

Wed 4/15

9:13 am-6:59 pm

1 stop8h 46m

$5,308

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

5:21 pm-3:54 pm

2 stops22h 33m

$369

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

7:36 pm-10:30 am

3 stops38h 54m

$592

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 12/27

7:36 pm-10:33 am

1 stop14h 57m

$947

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Manchester, New Hampshire to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Manchester to Panama?

American Airlines is the most popular carrier operating from Manchester to Panama

What airlines fly to Panama?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama from Manchester, New Hampshire according to our data. Copa Airlines is the first choice among our users, with 88% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Manchester, New Hampshire to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Panama

Fastest flight time

19h 40m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Panama takes 19h 40m
There are no direct flights from Manchester, New Hampshire to Panama. There are no popular flight routes from Manchester, New Hampshire to Panama.
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to Panama?

    Prices for flights from Manchester Airport to Panama are refreshed on a daily basis.

  • How old do you have to be to fly from Manchester Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Manchester to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Manchester to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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