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Cheap flights from Manchester, New Hampshire to Panama from $568

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Panama departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:33 pm - 2:45 pm
MHT
-
PTY
24h 12m
2 stops
United Airlines Logo
11:35 am - 1:44 pm
PTY
-
MHT
26h 09m
2 stops
$568United Airlines
Sat, Feb 28 - Wed, Mar 4
United Airlines Logo
7:28 pm - 1:45 pm
MHT
-
PTY
43h 17m
2 stops
United Airlines Logo
9:30 am - 1:44 pm
PTY
-
MHT
27h 14m
2 stops
$672United Airlines
Fri, Mar 20 - Fri, Mar 27
American Airlines Logo
5:02 pm - 1:40 pm
MHT
-
PTY
20h 38m
2 stops
American Airlines Logo
4:05 pm - 11:29 am
PTY
-
MHT
19h 24m
2 stops
$676American Airlines
Sat, Feb 28 - Fri, Mar 6
American Airlines Logo
6:00 am - 3:15 pm
MHT
-
PTY
9h 15m
2 stops
American Airlines Logo
2:40 pm - 11:29 am
PTY
-
MHT
20h 49m
2 stops
$903American Airlines
Fri, Feb 27 - Fri, Mar 6
American Airlines Logo
6:00 am - 3:15 pm
MHT
-
PTY
9h 15m
2 stops
American Airlines Logo
4:05 pm - 3:47 pm
PTY
-
MHT
23h 42m
2 stops
$961American Airlines
Sat, Feb 28 - Thu, Mar 5
Multiple Airlines Logo
9:59 am - 10:33 am
MHT
-
PTY
25h 34m
2 stops
Multiple Airlines Logo
6:09 pm - 5:29 pm
PTY
-
MHT
22h 20m
1 stop
$1,047Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
United Airlines Logo
2:19 pm - 6:13 am
MHT
-
PTY
16h 54m
1 stop
United Airlines Logo
9:11 am - 6:53 pm
PTY
-
MHT
8h 42m
1 stop
$5,329United Airlines
Fri, Mar 20 - Fri, Mar 27

United Airlines flights from Manchester, New Hampshire to Panama

Our best United Airlines deals on Manchester, New Hampshire to Panama flight tickets
United Airlines
Feb 28
MHT2:33 pmManchester
24h 12m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Mar 4
PTY11:35 amPanama City Tocumen Intl
26h 09m
2 stops
MHT1:44 pmManchester
$568
United Airlines
Mar 20
MHT7:28 pmManchester
43h 17m
2 stops
PTY1:45 pmPanama City Tocumen Intl
Mar 27
PTY9:30 amPanama City Tocumen Intl
27h 14m
2 stops
MHT1:44 pmManchester
$672
United Airlines
Mar 20
MHT2:19 pmManchester
16h 54m
1 stop
PTY6:13 amPanama City Tocumen Intl
Mar 27
PTY9:11 amPanama City Tocumen Intl
8h 42m
1 stop
MHT6:53 pmManchester
$5,329

American Airlines flights from Manchester, New Hampshire to Panama

Our best American Airlines deals on Manchester, New Hampshire to Panama flight tickets
American Airlines
Feb 28
MHT5:02 pmManchester
20h 38m
2 stops
PTY1:40 pmPanama City Tocumen Intl
Mar 6
PTY4:05 pmPanama City Tocumen Intl
19h 24m
2 stops
MHT11:29 amManchester
$676
American Airlines
Feb 27
MHT6:00 amManchester
9h 15m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 6
PTY2:40 pmPanama City Tocumen Intl
20h 49m
2 stops
MHT11:29 amManchester
$903
American Airlines
Feb 28
MHT6:00 amManchester
9h 15m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 5
PTY4:05 pmPanama City Tocumen Intl
23h 42m
2 stops
MHT3:47 pmManchester
$961

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 2/28

2:33 pm-2:45 pm

2 stops24h 12m

Panama City Tocumen Intl

Wed 3/4

11:35 am-1:44 pm

2 stops26h 09m

$568

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 3/20

7:28 pm-1:45 pm

2 stops43h 17m

Panama City Tocumen Intl

Fri 3/27

9:30 am-1:44 pm

2 stops27h 14m

$672

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 2/28

5:02 pm-1:40 pm

2 stops20h 38m

Panama City Tocumen Intl

Fri 3/6

4:05 pm-11:29 am

2 stops19h 24m

$676

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 2/27

6:00 am-3:15 pm

2 stops9h 15m

Panama City Tocumen Intl

Fri 3/6

2:40 pm-11:29 am

2 stops20h 49m

$903

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 2/28

6:00 am-3:15 pm

2 stops9h 15m

Panama City Tocumen Intl

Thu 3/5

4:05 pm-3:47 pm

2 stops23h 42m

$961

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 3/20

9:59 am-10:33 am

2 stops25h 34m

Panama City Tocumen Intl

Fri 3/27

6:09 pm-5:29 pm

1 stop22h 20m

$1,047

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 3/20

2:19 pm-6:13 am

1 stop16h 54m

Panama City Tocumen Intl

Fri 3/27

9:11 am-6:53 pm

1 stop8h 42m

$5,329

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama from

How to get the cheapest flight ticket from Manchester, New Hampshire to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Panama?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama from Manchester, New Hampshire according to our data. Copa Airlines is the first choice among our users, with 89% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Manchester, New Hampshire to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Panama

Fastest flight time

26h 50m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Panama takes 26h 50m
There are no direct flights from Manchester, New Hampshire to Panama. There are no popular flight routes from Manchester, New Hampshire to Panama.
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to Panama?

    Prices for flights from Manchester Airport to Panama are refreshed on a daily basis.

  • How old do you have to be to fly from Manchester Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Manchester to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Manchester to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Manchester. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Manchester to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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