What airlines fly to Central America?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Central America from Knoxville according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Central America. Keep in mind that there are 3 different airlines that fly to Central America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Central America?

American Airlines, GOL, and Avianca are the most popular carriers operating from Knoxville McGhee Tyson to Central America

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Central America?

Prices for flights from Knoxville McGhee Tyson Airport to Central America refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Central America?

As of September 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Central America.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Central America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Central America.

What documentation or ID do you need to fly to Central America?

The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$251 Cheap Flights from Knoxville to Central America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Central America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:09 pm - 12:25 pmTYS Knoxville McGhee Tyson-BZE Belize City Philip S.W.Goldson

21h 16m1 stop Tampa St. Petersburg

3:10 pm - 6:39 pmBZE Belize City Philip S.W.Goldson-TYS Knoxville McGhee Tyson

26h 29m1 stop Orlando Sanford Intl

$487Multiple Airlines

Wed, Jan 6 - Sun, Jan 10

5:07 pm - 1:21 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

21h 14m1 stop Orlando Sanford Intl

7:00 am - 11:18 amSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

27h 18m1 stop Orlando

$596Multiple Airlines

Fri, Jan 8 - Fri, Mar 5

6:00 am - 2:16 pmTYS Knoxville McGhee Tyson-LIR Liberia

9h 16m1 stop Miami

3:42 pm - 11:59 pmLIR Liberia-TYS Knoxville McGhee Tyson

7h 17m1 stop Miami

$596American Airlines

Sun, Jan 31 - Fri, Feb 5

8:51 pm - 2:16 pmTYS Knoxville McGhee Tyson-LIR Liberia

18h 25m2 stops Chicago O'Hare Intl Miami

1:39 pm - 11:59 pmLIR Liberia-TYS Knoxville McGhee Tyson

9h 20m1 stop Miami

$601American Airlines

Sun, Jan 31 - Fri, Feb 5

7:14 pm - 2:16 pmTYS Knoxville McGhee Tyson-LIR Liberia

20h 02m2 stops Charlotte Douglas Miami

3:42 pm - 11:27 amLIR Liberia-TYS Knoxville McGhee Tyson

18h 45m2 stops Miami Chicago O'Hare Intl

$601American Airlines

Sun, Jan 31 - Fri, Feb 5

5:30 am - 12:45 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

8h 15m1 stop Atlanta Hartsfield-Jackson

7:05 am - 3:05 pmSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

7h 00m1 stop Atlanta Hartsfield-Jackson

$608Delta

Wed, Feb 17 - Thu, Feb 25

5:30 am - 12:45 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

8h 15m1 stop Atlanta Hartsfield-Jackson

7:05 am - 3:05 pmSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

7h 00m1 stop Atlanta Hartsfield-Jackson

$608Delta

Mon, Feb 1 - Tue, Feb 9

10:45 am - 8:39 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

10h 54m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

9:05 am - 7:51 pmSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

9h 46m1 stop Newark

$608United Airlines

Tue, Jan 12 - Wed, Mar 3

12:00 pm - 6:16 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

7h 16m1 stop Houston George Bush Intcntl

9:05 am - 7:51 pmSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

9h 46m1 stop Newark

$608United Airlines

Tue, Jan 12 - Wed, Mar 3

5:07 pm - 1:21 pmTYS Knoxville McGhee Tyson-SJO San José Juan Santamaria Intl

21h 14m1 stop Orlando Sanford Intl

7:00 am - 9:23 pmSJO San José Juan Santamaria Intl-TYS Knoxville McGhee Tyson

13h 23m1 stop Orlando

$613Multiple Airlines

Fri, Jan 8 - Sat, Mar 6

Cheap last minute flights

Enter your travel dates to find the best prices.

7:15 am - 12:15 pmTYS Knoxville McGhee Tyson-SAL San Salvador El Salvador Intl

7h 00m1 stop Houston George Bush Intcntl

3:40 pm - 9:55 pmSAL San Salvador El Salvador Intl-TYS Knoxville McGhee Tyson

28h 15m1 stop Houston George Bush Intcntl

$755United Airlines

Sat, Sep 26 - Mon, Sep 28

5:45 am - 8:49 pmTYS Knoxville McGhee Tyson-SAL San Salvador El Salvador Intl

17h 04m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

3:40 pm - 9:55 pmSAL San Salvador El Salvador Intl-TYS Knoxville McGhee Tyson

28h 15m1 stop Houston George Bush Intcntl

$759United Airlines

Sat, Sep 26 - Mon, Sep 28

2:00 pm - 11:24 amTYS Knoxville McGhee Tyson-SAL San Salvador El Salvador Intl

23h 24m2 stops Charlotte Douglas Miami

12:24 pm - 11:43 amSAL San Salvador El Salvador Intl-TYS Knoxville McGhee Tyson

21h 19m2 stops Miami Philadelphia

$787American Airlines

Sat, Sep 26 - Mon, Sep 28

6:05 am - 12:22 pmTYS Knoxville McGhee Tyson-BZE Belize City Philip S.W.Goldson

8h 17m1 stop Miami

2:30 pm - 11:07 pmBZE Belize City Philip S.W.Goldson-TYS Knoxville McGhee Tyson

6h 37m1 stop Miami

$825American Airlines

Mon, Sep 28 - Fri, Oct 2

6:16 pm - 12:22 pmTYS Knoxville McGhee Tyson-BZE Belize City Philip S.W.Goldson

20h 06m2 stops Washington, D.C. Reagan-National Miami

2:30 pm - 11:07 pmBZE Belize City Philip S.W.Goldson-TYS Knoxville McGhee Tyson

6h 37m1 stop Miami

$830American Airlines

Mon, Sep 28 - Fri, Oct 2

7:18 pm - 12:22 pmTYS Knoxville McGhee Tyson-BZE Belize City Philip S.W.Goldson

19h 04m2 stops Charlotte Douglas Miami

2:30 pm - 11:26 amBZE Belize City Philip S.W.Goldson-TYS Knoxville McGhee Tyson

18h 56m2 stops Miami Washington, D.C. Reagan-National

$830American Airlines

Mon, Sep 28 - Fri, Oct 2

7:25 pm - 8:30 amTYS Knoxville McGhee Tyson-SAP San Pedro Sula Ramon Villeda

15h 05m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

8:10 pm - 10:37 amSAP San Pedro Sula Ramon Villeda-TYS Knoxville McGhee Tyson

12h 27m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$845Multiple Airlines

Mon, Sep 28 - Mon, Oct 5

5:45 am - 10:55 amTYS Knoxville McGhee Tyson-SAL San Salvador El Salvador Intl

31h 10m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

5:40 pm - 10:37 amSAL San Salvador El Salvador Intl-TYS Knoxville McGhee Tyson

14h 57m2 stops Guatemala City La Aurora Washington, D.C. Dulles Intl

$867Avianca

Sat, Sep 26 - Mon, Sep 28

1:35 pm - 1:55 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 20m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 8:19 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

13h 49m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$939Avianca

Tue, Sep 29 - Wed, Sep 30

7:15 am - 2:14 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 59m1 stop Houston George Bush Intcntl

3:30 pm - 9:45 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

17h 15m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,015Copa Airlines

Tue, Sep 29 - Wed, Sep 30

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Delta flights from Knoxville to Central America

Our best Delta deals on Knoxville to Central America flight tickets

Delta

Jan 20

TYS12:00 pmKnoxville McGhee Tyson

11h 05m

1 stop

SJO10:05 pmSan José Juan Santamaria Intl

Jan 30

SJO3:55 pmSan José Juan Santamaria Intl

16h 17m

1 stop

TYS9:12 amKnoxville McGhee Tyson

$633

Delta

Oct 27

TYS5:40 amKnoxville McGhee Tyson

8h 05m

1 stop

LIR11:45 amLiberia

Nov 3

LIR2:00 pmLiberia

7h 02m

1 stop

TYS10:02 pmKnoxville McGhee Tyson

$636

Delta

Jan 11

TYS7:07 amKnoxville McGhee Tyson

15h 58m

1 stop

SJO10:05 pmSan José Juan Santamaria Intl

Mar 4

SJO2:10 pmSan José Juan Santamaria Intl

6h 35m

1 stop

TYS9:45 pmKnoxville McGhee Tyson

$649

American Airlines flights from Knoxville to Central America

Our best American Airlines deals on Knoxville to Central America flight tickets

American Airlines

Jan 31

TYS6:00 amKnoxville McGhee Tyson

9h 16m

1 stop

LIR2:16 pmLiberia

Feb 5

LIR3:42 pmLiberia

7h 17m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$596

American Airlines

Jan 31

TYS7:14 pmKnoxville McGhee Tyson

20h 02m

2 stops

LIR2:16 pmLiberia

Feb 5

LIR3:42 pmLiberia

18h 45m

2 stops

TYS11:27 amKnoxville McGhee Tyson

$601

American Airlines

Feb 19

TYS5:57 pmKnoxville McGhee Tyson

18h 48m

2 stops

RTB11:45 amCoxen Hole Roatan

Feb 26

RTB12:46 pmCoxen Hole Roatan

21h 17m

2 stops

TYS11:03 amKnoxville McGhee Tyson

$602

momondo Fare Finder

Use the filters below to find and compare flights from Knoxville to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBelize City

TYS Knoxville McGhee Tyson - BZE Belize City Philip S.W.Goldson

TYSBZE

Knoxville McGhee Tyson

Wed 1/6

4:09 pm-12:25 pm

1 stop21h 16m

Belize City Philip S.W.Goldson

Sun 1/10

3:10 pm-6:39 pm

1 stop26h 29m

$487

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Fri 1/8

5:07 pm-1:21 pm

1 stop21h 14m

San José Juan Santamaria Intl

Fri 3/5

7:00 am-11:18 am

1 stop27h 18m

$596

KnoxvilleLiberia

TYS Knoxville McGhee Tyson - LIR Liberia

TYSLIR

Knoxville McGhee Tyson

Sun 1/31

6:00 am-2:16 pm

1 stop9h 16m

Liberia

Fri 2/5

3:42 pm-11:59 pm

1 stop7h 17m

$596

KnoxvilleLiberia

TYS Knoxville McGhee Tyson - LIR Liberia

TYSLIR

Knoxville McGhee Tyson

Sun 1/31

8:51 pm-2:16 pm

2 stops18h 25m

Liberia

Fri 2/5

1:39 pm-11:59 pm

1 stop9h 20m

$601

KnoxvilleLiberia

TYS Knoxville McGhee Tyson - LIR Liberia

TYSLIR

Knoxville McGhee Tyson

Sun 1/31

7:14 pm-2:16 pm

2 stops20h 02m

Liberia

Fri 2/5

3:42 pm-11:27 am

2 stops18h 45m

$601

Quickest round-trip

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Wed 2/17

5:30 am-12:45 pm

1 stop8h 15m

San José Juan Santamaria Intl

Thu 2/25

7:05 am-3:05 pm

1 stop7h 00m

$608

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Mon 2/1

5:30 am-12:45 pm

1 stop8h 15m

San José Juan Santamaria Intl

Tue 2/9

7:05 am-3:05 pm

1 stop7h 00m

$608

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Tue 1/12

10:45 am-8:39 pm

2 stops10h 54m

San José Juan Santamaria Intl

Wed 3/3

9:05 am-7:51 pm

1 stop9h 46m

$608

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Tue 1/12

12:00 pm-6:16 pm

1 stop7h 16m

San José Juan Santamaria Intl

Wed 3/3

9:05 am-7:51 pm

1 stop9h 46m

$608

KnoxvilleSan José

TYS Knoxville McGhee Tyson - SJO San José Juan Santamaria Intl

TYSSJO

Knoxville McGhee Tyson

Fri 1/8

5:07 pm-1:21 pm

1 stop21h 14m

San José Juan Santamaria Intl

Sat 3/6

7:00 am-9:23 pm

1 stop13h 23m

$613

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Central America?

In general, August is the cheapest month to fly from Knoxville to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $586. If you don’t want to visit Central America in August, then you should wait until September to fly from Knoxville, when ticket prices are also cheap, with an average price of $600.

Can stopping save me money on Knoxville to Central America flights?

You could potentially save up to 3% on your flight if you consider stops on a Knoxville to Central America flight.

Cheap Knoxville to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Central America

Best Price Found	$251
Fastest flight time	6h 14m
Direct flights	None

The best one-way flight to Central America from Knoxville in the past 72 hours is $251. The best round-trip flight deal from Knoxville to Central America found on momondo in the last 72 hours is $487.

The fastest flight from Knoxville to Central America takes 6h 14m

There are no direct flights from Knoxville to Central America. There are no popular flight routes from Knoxville to Central America.

Search flight deals

Frequently asked questions about flying from Knoxville to Central America

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Central America?
Prices for flights from Knoxville McGhee Tyson Airport to Central America refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Central America?
As of September 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Central America.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Central America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Central America.
What documentation or ID do you need to fly to Central America?
The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Knoxville to Central America

Compare and see reviews for airlines that fly from Knoxville to Central America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $324	Free Cancellation	Rating 7.8 8,603 reviews	Search Delta flights
American Airlines	PriceFrom $414	Free Cancellation	Rating 7.0 12,089 reviews	Search American Airlines flights
United Airlines	PriceFrom $545	Free Cancellation	Rating 7.4 10,238 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Central America with flexible booking policies on momondo?

Yes. All flights to Central America from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Central America?

momondo helps you find the best flight between Knoxville and Central America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Central America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Central America from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.