What is the cheapest airline that flies from Knoxville McGhee Tyson to Central America?

United Airlines, American Airlines, and Southwest are the most popular carriers operating from Knoxville McGhee Tyson to Central America

What airlines fly to Central America?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Central America from Knoxville according to our data. American Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to Central America. Keep in mind that there are 3 different airlines that fly to Central America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Central America?

Prices for flights from Knoxville McGhee Tyson Airport to Central America refresh daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Central America?

As of March 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Central America.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Central America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Central America.

What documentation or ID do you need to fly to Central America?

The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$207 Cheap Flights from Knoxville to Central America in 2026

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Find the cheapest flights from Knoxville to Central America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:29 pm - 10:42 am

TYS

SJO

21h 13m

1 stop

12:19 pm - 3:41 pm

SJO

TYS

25h 22m

2 stops

$399Multiple Airlines

Mon, Mar 30 - Wed, Apr 8

3:29 pm - 10:42 am

TYS

SJO

21h 13m

1 stop

11:38 am - 12:24 pm

SJO

TYS

22h 46m

1 stop

$418Multiple Airlines

Mon, Mar 30 - Wed, Apr 8

8:20 am - 11:32 am

TYS

GUA

29h 12m

1 stop

12:10 pm - 12:25 pm

GUA

TYS

22h 15m

1 stop

$430Multiple Airlines

Sun, Apr 12 - Sun, Apr 19

9:33 pm - 11:32 am

TYS

GUA

15h 59m

1 stop

12:10 pm - 9:48 pm

GUA

TYS

31h 38m

2 stops

$454Multiple Airlines

Sun, Apr 12 - Sun, Apr 19

5:45 am - 11:29 am

TYS

SAL

7h 44m

1 stop

1:15 am - 6:07 pm

SAL

TYS

14h 52m

1 stop

$489United Airlines

Wed, Jun 10 - Mon, Aug 3

8:20 am - 9:35 pm

TYS

SAL

15h 15m

2 stops

3:40 pm - 10:08 am

SAL

TYS

16h 28m

2 stops

$493United Airlines

Wed, Jun 3 - Mon, Aug 17

6:00 am - 11:22 am

TYS

SAL

7h 22m

1 stop

12:40 pm - 6:40 pm

SAL

TYS

28h 00m

1 stop

$500American Airlines

Tue, May 26 - Wed, Aug 12

7:05 am - 6:37 pm

TYS

PTY

12h 32m

1 stop

7:55 am - 11:12 pm

PTY

TYS

14h 17m

1 stop

$529Copa Airlines

Tue, May 19 - Tue, Jun 2

6:07 pm - 12:13 pm

TYS

PTY

19h 06m

2 stops

1:14 pm - 11:59 pm

PTY

TYS

9h 45m

1 stop

$531American Airlines

Mon, May 25 - Wed, Jun 3

7:00 am - 6:37 pm

TYS

PTY

12h 37m

2 stops

10:00 am - 12:30 am

PTY

TYS

13h 30m

2 stops

$533Copa Airlines

Tue, May 19 - Tue, Jun 2

American Airlines flights from Knoxville to Central America

Our best American Airlines deals on Knoxville to Central America flight tickets

American Airlines

May 26

TYS6:00 amKnoxville McGhee Tyson

7h 22m

1 stop

SAL11:22 amSan Salvador El Salvador Intl

Aug 12

SAL12:40 pmSan Salvador El Salvador Intl

28h 00m

1 stop

TYS6:40 pmKnoxville McGhee Tyson

$500

American Airlines

May 27

TYS6:00 amKnoxville McGhee Tyson

14h 42m

1 stop

SAL6:42 pmSan Salvador El Salvador Intl

Aug 12

SAL12:40 pmSan Salvador El Salvador Intl

28h 00m

1 stop

TYS6:40 pmKnoxville McGhee Tyson

$520

American Airlines

May 25

TYS7:59 pmKnoxville McGhee Tyson

17h 23m

2 stops

SAL11:22 amSan Salvador El Salvador Intl

Jun 5

SAL6:00 amSan Salvador El Salvador Intl

15h 59m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$529

Southwest flights from Knoxville to Central America

Our best Southwest deals on Knoxville to Central America flight tickets

Southwest

Jul 16

TYS7:30 amKnoxville McGhee Tyson

14h 10m

2 stops

SJO7:40 pmSan José Juan Santamaria Intl

Jul 21

SJO8:45 amSan José Juan Santamaria Intl

10h 30m

2 stops

TYS9:15 pmKnoxville McGhee Tyson

$587

Southwest

May 25

TYS6:35 amKnoxville McGhee Tyson

14h 25m

2 stops

SJO7:00 pmSan José Juan Santamaria Intl

Jun 10

SJO8:45 amSan José Juan Santamaria Intl

10h 30m

2 stops

TYS9:15 pmKnoxville McGhee Tyson

$629

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Mon 3/30

3:29 pm-10:42 am

1 stop21h 13m

San José Juan Santamaria Intl

Wed 4/8

12:19 pm-3:41 pm

2 stops25h 22m

$399

KnoxvilleSan José

TYS - SJO

TYSSJO

Knoxville McGhee Tyson

Mon 3/30

3:29 pm-10:42 am

1 stop21h 13m

San José Juan Santamaria Intl

Wed 4/8

11:38 am-12:24 pm

1 stop22h 46m

$418

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 4/12

8:20 am-11:32 am

1 stop29h 12m

Guatemala City La Aurora

Sun 4/19

12:10 pm-12:25 pm

1 stop22h 15m

$430

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 4/12

9:33 pm-11:32 am

1 stop15h 59m

Guatemala City La Aurora

Sun 4/19

12:10 pm-9:48 pm

2 stops31h 38m

$454

Quickest round-trip

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Wed 6/10

5:45 am-11:29 am

1 stop7h 44m

San Salvador El Salvador Intl

Mon 8/3

1:15 am-6:07 pm

1 stop14h 52m

$489

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Wed 6/3

8:20 am-9:35 pm

2 stops15h 15m

San Salvador El Salvador Intl

Mon 8/17

3:40 pm-10:08 am

2 stops16h 28m

$493

KnoxvilleSan Salvador

TYS - SAL

TYSSAL

Knoxville McGhee Tyson

Tue 5/26

6:00 am-11:22 am

1 stop7h 22m

San Salvador El Salvador Intl

Wed 8/12

12:40 pm-6:40 pm

1 stop28h 00m

$500

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 5/19

7:05 am-6:37 pm

1 stop12h 32m

Panama City Tocumen Intl

Tue 6/2

7:55 am-11:12 pm

1 stop14h 17m

$529

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 5/25

6:07 pm-12:13 pm

2 stops19h 06m

Panama City Tocumen Intl

Wed 6/3

1:14 pm-11:59 pm

1 stop9h 45m

$531

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 5/19

7:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Tue 6/2

10:00 am-12:30 am

2 stops13h 30m

$533

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Central America?

In general, August is the cheapest month to fly from Knoxville to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $511. If you don’t want to visit Central America in August, then you should wait until November to fly from Knoxville, when ticket prices are also cheap, with an average price of $530.

Cheap Knoxville to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Central America

Fastest flight time	6h 20m
Direct flights	None

The fastest flight from Knoxville to Central America takes 6h 20m

There are no direct flights from Knoxville to Central America. There are no popular flight routes from Knoxville to Central America.

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Central America?
Prices for flights from Knoxville McGhee Tyson Airport to Central America refresh daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Central America?
As of March 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Central America.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Central America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Central America.
What documentation or ID do you need to fly to Central America?
The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Knoxville to Central America

Compare and see reviews for airlines that fly from Knoxville to Central America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $261	Free Cancellation	Rating 7.4 9,429 reviews	Search United Airlines flights
Delta	PriceFrom $269	Free Cancellation	Rating 7.9 8,295 reviews	Search Delta flights
American Airlines	PriceFrom $357	Free Cancellation	Rating 7.1 11,468 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Central America with flexible booking policies on momondo?

Yes. All flights to Central America from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Central America?

momondo helps you find the best flight between Knoxville and Central America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Central America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Central America from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.