Cheap flights from Illinois to Panama from $290

The month of April is, on average, the cheapest month to fly to Panama from Illinois, with most prices found around $584. If you don’t want to visit Panama in April, then you should wait until March to fly from Illinois, when ticket prices are also cheap, with an average price of $593.

According to our data, Tuesday is the cheapest day to fly to Panama from Illinois. The lowest ticket price found for a Tuesday departure recently was $562. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Illinois to Panama for around $607.

In the evening is the cheapest time of day to fly from Illinois to Panama when you can find flight prices for as low as $488. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $595 per ticket.

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Illinois - Panama flight prices

You are more likely to see cheaper flights to Panama from Illinois when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $669 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Illinois for as low as $505 on momondo.

There are 3 cabin classes available to choose from on Illinois to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

United Airlines, Avianca, and Copa Airlines are the most popular carriers operating from Illinois to Panama

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Panama from Illinois according to our data. Copa Airlines is the first choice among our users, with 83% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

As of August 2026, there are 4 flights per day flying from Illinois to Panama. The most common time of day flights depart is 8:00AM, with 63% of flights taking off at noon.

As of August 2026, there are 29 flights per week flying from Illinois to Panama. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.