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Cheap flights from Illinois to Panama from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Panama departing on 4/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Illinois to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 5:07 pm
STL
-
PTY
10h 07m
1 stop
United Airlines Logo
4:41 pm - 9:23 am
PTY
-
STL
17h 42m
1 stop
$415United Airlines
Tue, Feb 17 - Wed, Feb 25
United Airlines Logo
7:41 am - 7:38 pm
STL
-
PTY
10h 57m
2 stops
United Airlines Logo
4:41 pm - 12:21 pm
PTY
-
STL
20h 40m
2 stops
$419United Airlines
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
6:20 pm - 12:40 pm
STL
-
PTY
18h 20m
1 stop
American Airlines Logo
3:10 pm - 12:44 pm
PTY
-
STL
21h 34m
2 stops
$429American Airlines
Mon, Mar 9 - Wed, Mar 18
American Airlines Logo
11:22 am - 12:40 pm
STL
-
PTY
25h 18m
1 stop
American Airlines Logo
1:40 pm - 10:32 am
PTY
-
STL
20h 52m
1 stop
$435American Airlines
Mon, Mar 9 - Wed, Mar 18
Avianca Logo
11:20 pm - 8:50 am
ORD
-
PTY
9h 30m
1 stop
Avianca Logo
10:05 pm - 1:15 pm
PTY
-
ORD
15h 10m
1 stop
$447Avianca
Thu, Mar 19 - Sun, Apr 5
Multiple Airlines Logo
2:35 pm - 12:10 am
ORD
-
PTY
9h 35m
1 stop
Multiple Airlines Logo
5:30 am - 6:35 pm
PTY
-
ORD
13h 05m
2 stops
$448Multiple Airlines
Sun, Mar 29 - Wed, Apr 8
Multiple Airlines Logo
11:20 pm - 8:50 am
ORD
-
PTY
9h 30m
1 stop
Multiple Airlines Logo
5:50 pm - 8:25 am
PTY
-
ORD
14h 35m
2 stops
$450Multiple Airlines
Mon, Mar 23 - Thu, Mar 26
Avianca Logo
11:20 pm - 8:50 am
ORD
-
PTY
9h 30m
1 stop
Avianca Logo
3:20 am - 1:15 pm
PTY
-
ORD
9h 55m
1 stop
$453Avianca
Fri, Mar 20 - Tue, Mar 31
Delta Logo
6:00 am - 1:50 pm
EVV
-
PTY
6h 50m
1 stop
Delta Logo
3:15 pm - 10:20 pm
PTY
-
EVV
8h 05m
1 stop
$617Delta
Sun, Feb 15 - Thu, Feb 19
Delta Logo
6:00 am - 1:03 pm
MDW
-
PTY
7h 03m
1 stop
Delta Logo
2:20 pm - 10:29 pm
PTY
-
MDW
8h 09m
1 stop
$625Delta
Tue, Apr 7 - Mon, Apr 20

United Airlines flights from Illinois to Panama

Our best United Airlines deals on Illinois to Panama flight tickets
United Airlines
Feb 17
STL6:00 amLambert-St Louis
12h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 24
PTY4:41 pmPanama City Tocumen Intl
17h 42m
1 stop
STL9:23 amLambert-St Louis
$415
United Airlines
Apr 29
STL7:45 amLambert-St Louis
10h 52m
2 stops
PTY6:37 pmPanama City Tocumen Intl
May 6
PTY7:55 amPanama City Tocumen Intl
8h 06m
1 stop
STL4:01 pmLambert-St Louis
$419
United Airlines
Apr 21
STL6:00 amLambert-St Louis
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Apr 25
PTY7:55 amPanama City Tocumen Intl
14h 33m
1 stop
STL10:28 pmLambert-St Louis
$423

Delta flights from Illinois to Panama

Our best Delta deals on Illinois to Panama flight tickets
Delta
Feb 15
EVV6:00 amEvansville Dress Regional
6h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Feb 19
PTY3:15 pmPanama City Tocumen Intl
8h 05m
1 stop
EVV10:20 pmEvansville Dress Regional
$617
Delta
Mar 17
MDW6:00 amChicago Midway
7h 03m
1 stop
PTY1:03 pmPanama City Tocumen Intl
Mar 24
PTY2:28 pmPanama City Tocumen Intl
8h 03m
1 stop
MDW10:31 pmChicago Midway
$645
Delta
Mar 17
MDW6:34 pmChicago Midway
18h 29m
2 stops
PTY1:03 pmPanama City Tocumen Intl
Mar 24
PTY2:28 pmPanama City Tocumen Intl
8h 03m
1 stop
MDW10:31 pmChicago Midway
$649

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Illinois to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 2/17

6:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Wed 2/25

4:41 pm-9:23 am

1 stop17h 42m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 2/17

7:41 am-7:38 pm

2 stops10h 57m

Panama City Tocumen Intl

Tue 2/24

4:41 pm-12:21 pm

2 stops20h 40m

$419

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 3/9

6:20 pm-12:40 pm

1 stop18h 20m

Panama City Tocumen Intl

Wed 3/18

3:10 pm-12:44 pm

2 stops21h 34m

$429

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 3/9

11:22 am-12:40 pm

1 stop25h 18m

Panama City Tocumen Intl

Wed 3/18

1:40 pm-10:32 am

1 stop20h 52m

$435

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/19

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Sun 4/5

10:05 pm-1:15 pm

1 stop15h 10m

$447

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 3/29

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Wed 4/8

5:30 am-6:35 pm

2 stops13h 05m

$448

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 3/23

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Thu 3/26

5:50 pm-8:25 am

2 stops14h 35m

$450

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 3/20

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Tue 3/31

3:20 am-1:15 pm

1 stop9h 55m

$453

EvansvillePanama City

EVV - PTY

EVVPTY

Evansville Dress Regional

Sun 2/15

6:00 am-1:50 pm

1 stop6h 50m

Panama City Tocumen Intl

Thu 2/19

3:15 pm-10:20 pm

1 stop8h 05m

$617

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 4/7

6:00 am-1:03 pm

1 stop7h 03m

Panama City Tocumen Intl

Mon 4/20

2:20 pm-10:29 pm

1 stop8h 09m

$625

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Illinois to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of July is, on average, the cheapest month to fly to Panama from Illinois, with most prices found around $523. If you don’t want to visit Panama in July, then you should wait until September to fly from Illinois, when ticket prices are also cheap, with an average price of $534.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Illinois. The lowest ticket price found for a Tuesday departure recently was $530. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Illinois to Panama for around $584.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Illinois to Panama when you can find flight prices for as low as $496. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $577 per ticket.

What is the cheapest Illinois to Panama flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Illinois - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Illinois when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Illinois for as low as $535 on momondo.

What cabin class options are available on Illinois to Panama flights?

There are 3 cabin classes available to choose from on Illinois to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Illinois to Panama flights?

You could potentially save up to 81% on your flight if you consider stops on a Illinois to Panama flight.

Cheap Illinois to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Panama

Best Price Found

$179

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama

21 airports
The best one-way flight to Panama from Illinois in the past 72 hours is $179. The best round-trip flight deal from Illinois to Panama found on momondo in the last 72 hours is $376.
The fastest flight from Illinois to Panama takes 5h 13m
Direct flights go from Illinois to Panama every day.
There are 21 airports in Panama. From Illinois there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • When did momondo last update prices for flights from Illinois to Panama?

    Prices for flights from Illinois to Panama refresh daily.

  • How many operators does momondo search for flights from Illinois to Panama?

  • How old do you have to be to fly from Illinois to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Illinois to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Illinois to Panama?

Best airlines flying from Illinois to Panama

Compare and see reviews for airlines that fly from Illinois to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $272Free CancellationRating
6.6
2,496 reviews
Search Avianca flights
Copa AirlinesPriceFrom $463Free CancellationRating
7.6
1,557 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
9,190 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
8,087 reviews
Search Delta flights
American AirlinesPriceFrom $563Free CancellationRating
7.2
11,173 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Illinois to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Illinois to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Illinois to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Illinois to Panama?

momondo helps you find the best flight between Illinois and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Illinois to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Illinois to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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