Cheap flights from Florida to Panama from $126

The month of September is, on average, the cheapest month to fly to Panama from Florida, with most prices found around $411. If you don’t want to visit Panama in September, then you should wait until July to fly from Florida, when ticket prices are also cheap, with an average price of $428.

According to our data, Wednesday is the cheapest day to fly to Panama from Florida. The lowest ticket price found for a Wednesday departure recently was $383. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Florida to Panama for around $448.

At noon is the cheapest time of day to fly from Florida to Panama when you can find flight prices for as low as $378. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $462 per ticket.

Fly from Tampa to Panama City Tocumen Intl for the best Florida - Panama flight prices

You are more likely to see cheaper flights to Panama from Florida when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $469 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Florida for as low as $421 on momondo.

There are 3 cabin classes available to choose from on Florida to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Avianca, Copa Airlines, and United Airlines are the most popular carriers operating from Florida to Panama

Copa Airlines, American Airlines and Avianca are the top three most popular airlines that fly to Panama from Florida according to our data. Copa Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

The number of flights available between Florida and Panama is 9 per day as of March 2026. The most frequent departure time is 6:00PM, with 46% of daily flights leaving in the afternoon.

As of March 2026, there are 69 flights per week flying from Florida to Panama. The most common day of the week flights depart is Sat, with 43% of flights taking off on this day.