Cheap flights from District of Columbia to Panama from $337

The month of April is, on average, the cheapest month to fly to Panama from District of Columbia, with most prices found around $528. If you don’t want to visit Panama in April, then you should wait until February to fly from District of Columbia, when ticket prices are also cheap, with an average price of $591.

According to our data, Monday is the cheapest day to fly to Panama from District of Columbia. The lowest ticket price found for a Monday departure recently was $584. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from District of Columbia to Panama for around $639.

In the evening is the cheapest time of day to fly from District of Columbia to Panama when you can find flight prices for as low as $547. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $667 per ticket.

Fly from Baltimore/Washington to Panama City Tocumen Intl for the best District of Columbia - Panama flight prices

You are more likely to see cheaper flights to Panama from District of Columbia when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $661 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from District of Columbia for as low as $566 on momondo.

There are 3 cabin classes available to choose from on District of Columbia to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

American Airlines, Avianca, and Copa Airlines are the most popular carriers operating from District of Columbia to Panama

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama from District of Columbia according to our data. Copa Airlines is the first choice among our users, with 85% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

As of November 2026, there are 5 flights per day flying from District of Columbia to Panama. The most common time of day flights depart is 3:00PM, with 39% of flights taking off in the afternoon.

40 flights are operational weekly from District of Columbia to Panama as of November 2026. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.