What airlines fly to Panama?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Panama from Detroit according to our data. Delta is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to Panama?

Prices for flights from Detroit to Panama are updated daily.

How many operators does momondo search for flights from Detroit to Panama?

As of August 2025, there are 3 operators available to choose from for flights from Detroit to Panama.

How old do you have to be to fly from Detroit to Panama?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$185 Cheap Flights from Detroit to Panama in 2025

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Find the cheapest flights from Detroit to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

6:30 am - 9:10 pmDTW-PTY

15h 40m2 stops

10:05 pm - 8:14 pmPTY-DTW

21h 09m2 stops

$402

Find Deal

Thu, Sep 25 - Sun, Sep 28

6:30 am - 9:10 pmDTW-PTY

15h 40m2 stops

10:05 pm - 8:14 pmPTY-DTW

21h 09m2 stops

$404

Find Deal

Thu, Sep 25 - Sun, Sep 28

6:30 am - 9:10 pmDTW-PTY

15h 40m2 stops

10:05 pm - 8:14 pmPTY-DTW

21h 09m2 stops

$427

Find Deal

Sat, Sep 20 - Sat, Sep 27

6:30 am - 9:10 pmDTW-PTY

15h 40m2 stops

3:20 am - 8:14 pmPTY-DTW

15h 54m2 stops

$434

Find Deal

Thu, Sep 25 - Sat, Sep 27

7:00 am - 1:00 amDTW-PTY

18h 00m2 stops

2:55 pm - 2:09 pmPTY-DTW

23h 14m2 stops

$435

Find Deal

Thu, Nov 13 - Mon, Nov 17

6:30 am - 12:10 amDTW-PTY

18h 40m2 stops

3:20 am - 8:14 pmPTY-DTW

15h 54m2 stops

$436

Find Deal

Thu, Sep 4 - Wed, Sep 10

6:30 am - 12:10 amDTW-PTY

18h 40m2 stops

3:20 am - 8:14 pmPTY-DTW

15h 54m2 stops

$438

Find Deal

Thu, Sep 4 - Wed, Sep 10

6:41 am - 12:45 amDTW-PTY

19h 04m2 stops

3:20 am - 11:43 pmPTY-DTW

19h 23m2 stops

$441

Find Deal

Fri, Sep 19 - Thu, Sep 25

6:30 am - 9:10 pmDTW-PTY

15h 40m2 stops

10:05 pm - 8:14 pmPTY-DTW

21h 09m2 stops

$443

Find Deal

Thu, Sep 4 - Thu, Sep 11

5:54 am - 1:25 pmDTW-PTY

7h 31m1 stop

2:45 pm - 10:44 pmPTY-DTW

7h 59m1 stop

$578American Airlines

Find Deal

Fri, Dec 5 - Fri, Dec 12

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sun 9/28

10:05 pm-8:14 pm

2 stops21h 09m

$402

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sun 9/28

10:05 pm-8:14 pm

2 stops21h 09m

$404

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 9/20

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sat 9/27

10:05 pm-8:14 pm

2 stops21h 09m

$427

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sat 9/27

3:20 am-8:14 pm

2 stops15h 54m

$434

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 11/13

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Mon 11/17

2:55 pm-2:09 pm

2 stops23h 14m

$435

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-12:10 am

2 stops18h 40m

Panama City Tocumen Intl

Wed 9/10

3:20 am-8:14 pm

2 stops15h 54m

$436

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-12:10 am

2 stops18h 40m

Panama City Tocumen Intl

Wed 9/10

3:20 am-8:14 pm

2 stops15h 54m

$438

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/19

6:41 am-12:45 am

2 stops19h 04m

Panama City Tocumen Intl

Thu 9/25

3:20 am-11:43 pm

2 stops19h 23m

$441

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Thu 9/11

10:05 pm-8:14 pm

2 stops21h 09m

$443

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 12/5

5:54 am-1:25 pm

1 stop7h 31m

Panama City Tocumen Intl

Fri 12/12

2:45 pm-10:44 pm

1 stop7h 59m

$578

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Detroit, with most prices found around $637. If you don’t want to visit Panama in August, then you should wait until April to fly from Detroit, when ticket prices are also cheap, with an average price of $648.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Detroit. The lowest ticket price found for a Wednesday departure recently was $733. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to Panama for around $891.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Detroit to Panama when you can find flight prices for as low as $767. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $794 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $860 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Detroit for as low as $622 on momondo.

Cheap Detroit to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama

Best Price Found	$185
Fastest flight time	7h 31m
Direct flights	None
Airports in Panama	1 airport

The best one-way flight to Panama from Detroit in the past 72 hours is $185. The best round-trip flight deal from Detroit to Panama found on momondo in the last 72 hours is $402.

The fastest flight from Detroit to Panama takes 7h 31m

There are no direct flights from Detroit to Panama. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - Panama City Tocumen Intl Airport.

There is 1 airport near Panama: Panama City Tocumen Intl (PTY)

Search flight deals

When did momondo last update prices for flights from Detroit to Panama?
Prices for flights from Detroit to Panama are updated daily.
How many operators does momondo search for flights from Detroit to Panama?
As of August 2025, there are 3 operators available to choose from for flights from Detroit to Panama.
How old do you have to be to fly from Detroit to Panama?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Panama

Compare and see reviews for airlines that fly from Detroit to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $578	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $608	Free Cancellation	Rating 7.4 8,917 reviews	Search United Airlines flights
Delta	PriceFrom $608	Free Cancellation	Rating 8.0 7,985 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Detroit to Panama. momondo saves you time and could save you money on your trip.

Can I find flights from Detroit to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama?

momondo helps you find the best flight between Detroit and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.