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Cheap flights from Detroit to La Crosse from $494

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to La Crosse departing on 2/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:18 am - 2:06 pm
DTW
-
LSE
6h 48m
1 stop
American Airlines Logo
5:20 am - 12:32 pm
LSE
-
DTW
6h 12m
1 stop
$494American Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
8:59 am - 5:59 pm
DTW
-
LSE
10h 00m
2 stops
American Airlines Logo
5:20 am - 12:32 pm
LSE
-
DTW
6h 12m
1 stop
$500American Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
6:41 am - 2:06 pm
DTW
-
LSE
8h 25m
2 stops
American Airlines Logo
5:20 am - 5:41 pm
LSE
-
DTW
11h 21m
2 stops
$505American Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
5:27 pm - 11:59 pm
DTW
-
LSE
7h 32m
1 stop
American Airlines Logo
6:00 am - 9:33 pm
LSE
-
DTW
14h 33m
1 stop
$659American Airlines
Tue, Jun 2 - Thu, Jun 4
American Airlines Logo
1:41 pm - 11:59 pm
DTW
-
LSE
11h 18m
2 stops
American Airlines Logo
11:39 am - 9:33 pm
LSE
-
DTW
8h 54m
1 stop
$698American Airlines
Tue, Jun 2 - Thu, Jun 4
American Airlines Logo
6:00 am - 4:59 pm
DTW
-
LSE
11h 59m
2 stops
American Airlines Logo
11:39 am - 12:33 am
LSE
-
DTW
11h 54m
2 stops
$801American Airlines
Tue, Jun 2 - Thu, Jun 4
American Airlines Logo
8:18 am - 11:01 am
DTW
-
LSE
3h 43m
1 stop
American Airlines Logo
6:29 pm - 12:31 am
LSE
-
DTW
5h 02m
1 stop
$858American Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
1:02 pm - 5:59 pm
DTW
-
LSE
5h 57m
1 stop
American Airlines Logo
11:31 am - 7:14 pm
LSE
-
DTW
6h 43m
2 stops
$864American Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
3:37 pm - 11:36 pm
DTW
-
LSE
8h 59m
2 stops
American Airlines Logo
11:31 am - 7:14 pm
LSE
-
DTW
6h 43m
2 stops
$869American Airlines
Mon, Feb 23 - Thu, Feb 26

American Airlines flights from Detroit to La Crosse

Our best American Airlines deals on Detroit to La Crosse flight tickets
American Airlines
Jun 2
DTW5:27 pmDetroit Metropolitan Wayne County
7h 32m
1 stop
LSE11:59 pmLa Crosse
Jun 4
LSE6:00 amLa Crosse
14h 33m
1 stop
DTW9:33 pmDetroit Metropolitan Wayne County
$659
American Airlines
Jun 2
DTW1:41 pmDetroit Metropolitan Wayne County
11h 18m
2 stops
LSE11:59 pmLa Crosse
Jun 4
LSE5:29 pmLa Crosse
22h 28m
1 stop
DTW4:57 pmDetroit Metropolitan Wayne County
$698
American Airlines
Jun 2
DTW6:00 amDetroit Metropolitan Wayne County
11h 59m
2 stops
LSE4:59 pmLa Crosse
Jun 4
LSE11:39 amLa Crosse
11h 54m
2 stops
DTW12:33 amDetroit Metropolitan Wayne County
$801

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Detroit to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 2/24

8:18 am-2:06 pm

1 stop6h 48m

La Crosse

Sat 2/28

5:20 am-12:32 pm

1 stop6h 12m

$494

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 2/24

8:59 am-5:59 pm

2 stops10h 00m

La Crosse

Sat 2/28

5:20 am-12:32 pm

1 stop6h 12m

$500

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 2/24

6:41 am-2:06 pm

2 stops8h 25m

La Crosse

Sat 2/28

5:20 am-5:41 pm

2 stops11h 21m

$505

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 6/2

5:27 pm-11:59 pm

1 stop7h 32m

La Crosse

Thu 6/4

6:00 am-9:33 pm

1 stop14h 33m

$659

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 6/2

1:41 pm-11:59 pm

2 stops11h 18m

La Crosse

Thu 6/4

11:39 am-9:33 pm

1 stop8h 54m

$698

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 6/2

6:00 am-4:59 pm

2 stops11h 59m

La Crosse

Thu 6/4

11:39 am-12:33 am

2 stops11h 54m

$801

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 2/23

8:18 am-11:01 am

1 stop3h 43m

La Crosse

Thu 2/26

6:29 pm-12:31 am

1 stop5h 02m

$858

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 2/23

1:02 pm-5:59 pm

1 stop5h 57m

La Crosse

Thu 2/26

11:31 am-7:14 pm

2 stops6h 43m

$864

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 2/23

3:37 pm-11:36 pm

2 stops8h 59m

La Crosse

Thu 2/26

11:31 am-7:14 pm

2 stops6h 43m

$869

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit to La Crosse

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to La Crosse according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to La Crosse (DTT to LSE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to La Crosse

Fastest flight time

8h 54m

Direct flights

None
The fastest flight from Detroit to La Crosse takes 8h 54m
There are no direct flights from Detroit to La Crosse. There are no popular flight routes from Detroit to La Crosse.
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  • How far is Detroit to La Crosse by plane?

    La Crosse is 425.0 mi away from Detroit. Flights usually cover this in 8h 54m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to La Crosse Airport?

    Prices for flights from Detroit to La Crosse Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to La Crosse Airport?

  • How old do you have to be to fly from Detroit to La Crosse Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The required travel and health documents for your La Crosse Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at La Crosse Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to La Crosse

Compare and see reviews for airlines that fly from Detroit to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights

  • How do I get Price Alerts for flights from Detroit to La Crosse?

    Price Alerts will notify you by email when the price for flights to La Crosse from Detroit decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

  • How can I save money on flights from Detroit to La Crosse with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to La Crosse?

It is quick and easy to find Detroit to La Crosse flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to La Crosse that suits you.

Can I find flights from Detroit to La Crosse with flexible booking policies on momondo?

momondo does allow users to show only those flights to La Crosse from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to La Crosse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to La Crosse from Detroit.

I’m not ready to book a flight from Detroit to La Crosse right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to La Crosse now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to La Crosse and let you know when they change.

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