Latest deals
Insights
FAQs
Price Alerts

Cheap flights from the Czech Republic to Des Moines from $451

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the Czech Republic to Des Moines departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from the Czech Republic to Des Moines

Recent round-trip flight deals from the Czech Republic to Des Moines

Enter your travel dates to find the best prices.
United Airlines Logo
7:15 am - 10:50 pm
PRG
-
DSM
22h 35m
2 stops
United Airlines Logo
1:27 pm - 1:05 pm
DSM
-
PRG
16h 38m
2 stops
$1,104United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
7:15 am - 8:36 pm
PRG
-
DSM
20h 21m
2 stops
United Airlines Logo
6:45 pm - 10:25 pm
DSM
-
PRG
20h 40m
2 stops
$1,105United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
7:05 am - 8:36 pm
PRG
-
DSM
20h 31m
2 stops
United Airlines Logo
6:45 pm - 10:40 pm
DSM
-
PRG
20h 55m
2 stops
$1,115United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
7:05 am - 8:36 pm
PRG
-
DSM
20h 31m
2 stops
United Airlines Logo
6:45 pm - 10:40 pm
DSM
-
PRG
20h 55m
2 stops
$1,116United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
7:05 am - 8:36 pm
PRG
-
DSM
20h 31m
2 stops
United Airlines Logo
6:45 pm - 10:40 pm
DSM
-
PRG
20h 55m
2 stops
$1,117United Airlines
Thu, Nov 5 - Mon, Nov 9
Delta Logo
11:15 am - 10:18 am
PRG
-
DSM
30h 03m
2 stops
Delta Logo
5:56 pm - 9:40 pm
DSM
-
PRG
20h 44m
2 stops
$1,300Delta
Mon, Aug 17 - Fri, Aug 21
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
American Airlines Logo
6:22 pm - 4:50 pm
DSM
-
PRG
15h 28m
2 stops
$1,366American Airlines
Mon, Aug 17 - Fri, Aug 21
American Airlines Logo
10:15 am - 12:34 pm
PRG
-
DSM
33h 19m
1 stop
American Airlines Logo
5:40 am - 8:15 am
DSM
-
PRG
19h 35m
1 stop
$1,377American Airlines
Mon, Aug 17 - Fri, Aug 21
Multiple Airlines Logo
12:30 pm - 10:26 am
PRG
-
DSM
28h 56m
2 stops
Multiple Airlines Logo
8:00 am - 8:30 am
DSM
-
PRG
17h 30m
3 stops
$1,871Multiple Airlines
Mon, Aug 17 - Fri, Aug 21
Air Canada Logo
9:35 am - 9:23 pm
PRG
-
DSM
18h 48m
3 stops
Air Canada Logo
8:00 am - 8:30 am
DSM
-
PRG
17h 30m
3 stops
$2,437Air Canada
Mon, Aug 17 - Fri, Aug 21

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Czech Republic to Des Moines

Our best American Airlines deals on Czech Republic to Des Moines flight tickets
American Airlines
Aug 17
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
Aug 21
DSM6:22 pmDes Moines
15h 28m
2 stops
PRG4:50 pmVáclav Havel Prague
$1,366
American Airlines
Aug 17
PRG10:15 amVáclav Havel Prague
33h 19m
1 stop
DSM12:34 pmDes Moines
Aug 21
DSM5:40 amDes Moines
19h 35m
1 stop
PRG8:15 amVáclav Havel Prague
$1,377

United Airlines flights from Czech Republic to Des Moines

Our best United Airlines deals on Czech Republic to Des Moines flight tickets
United Airlines
Nov 5
PRG7:15 amVáclav Havel Prague
22h 35m
2 stops
DSM10:50 pmDes Moines
Nov 9
DSM1:27 pmDes Moines
16h 38m
2 stops
PRG1:05 pmVáclav Havel Prague
$1,104
United Airlines
Nov 5
PRG7:15 amVáclav Havel Prague
20h 21m
2 stops
DSM8:36 pmDes Moines
Nov 9
DSM6:45 pmDes Moines
20h 40m
2 stops
PRG10:25 pmVáclav Havel Prague
$1,105
United Airlines
Nov 5
PRG7:05 amVáclav Havel Prague
20h 31m
2 stops
DSM8:36 pmDes Moines
Nov 9
DSM6:45 pmDes Moines
20h 55m
2 stops
PRG10:40 pmVáclav Havel Prague
$1,115

momondo Fare Finder

 
Customize your flight search to find flights from Czech Republic to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from the Czech Republic to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 11/5

7:15 am-10:50 pm

2 stops22h 35m

Des Moines

Mon 11/9

1:27 pm-1:05 pm

2 stops16h 38m

$1,104

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 11/5

7:15 am-8:36 pm

2 stops20h 21m

Des Moines

Mon 11/9

6:45 pm-10:25 pm

2 stops20h 40m

$1,105

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 11/5

7:05 am-8:36 pm

2 stops20h 31m

Des Moines

Mon 11/9

6:45 pm-10:40 pm

2 stops20h 55m

$1,115

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 11/5

7:05 am-8:36 pm

2 stops20h 31m

Des Moines

Mon 11/9

6:45 pm-10:40 pm

2 stops20h 55m

$1,116

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Thu 11/5

7:05 am-8:36 pm

2 stops20h 31m

Des Moines

Mon 11/9

6:45 pm-10:40 pm

2 stops20h 55m

$1,117

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Mon 8/17

11:15 am-10:18 am

2 stops30h 03m

Des Moines

Fri 8/21

5:56 pm-9:40 pm

2 stops20h 44m

$1,300
Quickest round-trip

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Mon 8/17

10:15 am-10:06 pm

1 stop18h 51m

Des Moines

Fri 8/21

6:22 pm-4:50 pm

2 stops15h 28m

$1,366

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Mon 8/17

10:15 am-12:34 pm

1 stop33h 19m

Des Moines

Fri 8/21

5:40 am-8:15 am

1 stop19h 35m

$1,377

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Mon 8/17

12:30 pm-10:26 am

2 stops28h 56m

Des Moines

Fri 8/21

8:00 am-8:30 am

3 stops17h 30m

$1,871

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

Mon 8/17

9:35 am-9:23 pm

3 stops18h 48m

Des Moines

Fri 8/21

8:00 am-8:30 am

3 stops17h 30m

$2,437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Czech Republic to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Czech Republic to Des Moines flights?

You could potentially save up to 23% on your flight if you consider stops on a Czech Republic to Des Moines flight.

Cheap Czech Republic to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Czech Republic to Des Moines

Fastest flight time

20h 31m

Direct flights

None
The fastest flight from Czech Republic to Des Moines takes 20h 31m
There are no direct flights from Czech Republic to Des Moines. There are no popular flight routes from Czech Republic to Des Moines.
Search flight deals

Frequently asked questions about flying from the Czech Republic to Des Moines

  • When did momondo last update prices for flights from Czech Republic to Des Moines Airport?

    Prices for flights from Czech Republic to Des Moines Airport refresh daily.

  • How old do you have to be to fly from Czech Republic to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Czech Republic to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Johnston
Osceola
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Czech Republic to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Czech Republic.

Can I find flights from Czech Republic to Des Moines with flexible booking policies on momondo?

Flights from Czech Republic to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Czech Republic to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Czech Republic.

I’m not ready to book a flight from Czech Republic to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Czech Republic and alert you when they change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 8/31
Mon 9/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States