Cheap flights from Colorado to Sioux Falls from $106

The cheapest month to fly to Sioux Falls from Colorado is in October. Flight prices, which tend to average around $240, are often lower during this time because this is during the off-season. If you’re not able to fly to Sioux Falls in October, then December is your next best option. Flight prices from Colorado to Sioux Falls during December average around $244.

The cheapest day to depart on your flight to Sioux Falls is on a Friday when prices can be found for as low as $260. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Colorado because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $419.

Our most recent data shows that the best time of day to fly to Sioux Falls is in the afternoon. Flights from Colorado to Sioux Falls during this time can be as low as $260. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $338 on average. Flights to Sioux Falls from Colorado at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Denver Intl to Sioux Falls Joe Foss Field for the best Colorado - Sioux Falls Joe Foss Field flight prices

You are more likely to see cheaper flights to Sioux Falls from Colorado when booking weeks ahead of your departure date. In general, you can expect to find flights to Sioux Falls for around $289 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sioux Falls from Colorado for as low as $232 on momondo.

There are 3 cabin classes available to choose from on Colorado to Sioux Falls flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

As of September 2026, there are 7 flights per day flying from Colorado to Sioux Falls. The most common time of day flights depart is 5:00PM, with 67% of flights taking off in the afternoon.

As of September 2026, 53 flights take off from Colorado and land in Sioux Falls each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.