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Cheap flights from Charleston to Central America from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Central America departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Central America

Cheap round-trip flights

Spirit Airlines Logo
5:40 pm - 12:55 amCHS-GUA
8h 15m1 stop
Spirit Airlines Logo
1:59 am - 10:45 amGUA-CHS
7h 46m1 stop
$201Spirit Airlines
Find Deal
Sat, Nov 8 - Thu, Nov 13
Spirit Airlines Logo
5:40 pm - 12:26 pmCHS-GUA
19h 46m1 stop
Spirit Airlines Logo
1:22 pm - 10:45 amGUA-CHS
20h 23m1 stop
$232Spirit Airlines
Find Deal
Sat, Nov 8 - Fri, Nov 14
Delta Logo
5:30 am - 11:25 amCHS-LIR
6h 55m1 stop
Delta Logo
2:15 pm - 11:39 pmLIR-CHS
8h 24m1 stop
$265Delta
Find Deal
Sat, Jan 17 - Fri, Jan 23
American Airlines Logo
8:39 pm - 12:20 pmCHS-LIR
16h 41m1 stop
American Airlines Logo
1:55 pm - 10:21 amLIR-CHS
19h 26m2 stops
$269American Airlines
Find Deal
Sat, Jan 17 - Fri, Jan 23
Logo
5:40 pm - 12:55 amCHS-GUA
8h 15m1 stop
Logo
2:19 pm - 10:45 amGUA-CHS
19h 26m2 stops
$285
Find Deal
Sat, Nov 8 - Fri, Nov 14
Logo
10:11 am - 11:30 amCHS-SJO
27h 19m1 stop
Logo
11:37 am - 8:37 amSJO-CHS
19h 00m1 stop
$286
Find Deal
Fri, Oct 24 - Mon, Oct 27
American Airlines Logo
6:00 am - 12:00 pmCHS-SJO
8h 00m1 stop
American Airlines Logo
2:40 pm - 11:59 pmSJO-CHS
7h 19m1 stop
$364American Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Delta Logo
6:40 am - 12:56 pmCHS-PTY
7h 16m1 stop
Delta Logo
3:37 pm - 10:48 pmPTY-CHS
7h 11m1 stop
$369Delta
Find Deal
Wed, Oct 29 - Wed, Nov 26
United Airlines Logo
6:30 am - 6:38 pmCHS-PTY
13h 08m1 stop
United Airlines Logo
4:41 pm - 4:16 pmPTY-CHS
23h 35m1 stop
$378United Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 27
United Airlines Logo
11:00 am - 8:02 pmCHS-PTY
9h 02m1 stop
United Airlines Logo
11:55 pm - 9:50 amPTY-CHS
9h 55m1 stop
$409United Airlines
Find Deal
Fri, Jan 16 - Sun, Feb 1

Spirit Airlines flights from Charleston to Central America

Our best Spirit Airlines deals on Charleston to Central America flight tickets
Spirit Airlines
Nov 8
CHS5:40 pmCharleston
8h 15m
1 stop
GUA12:55 amGuatemala City La Aurora
Nov 13
GUA1:59 amGuatemala City La Aurora
7h 46m
1 stop
CHS10:45 amCharleston
$201
Find similar
Spirit Airlines
Nov 8
CHS5:40 pmCharleston
19h 46m
1 stop
GUA12:26 pmGuatemala City La Aurora
Nov 14
GUA1:22 pmGuatemala City La Aurora
20h 23m
1 stop
CHS10:45 amCharleston
$232
Find similar
Spirit Airlines
Nov 8
CHS5:40 pmCharleston
21h 35m
2 stops
GUA2:15 pmGuatemala City La Aurora
Nov 13
GUA1:59 amGuatemala City La Aurora
7h 46m
1 stop
CHS10:45 amCharleston
$236
Find similar

JetBlue flights from Charleston to Central America

Our best JetBlue deals on Charleston to Central America flight tickets
JetBlue
Nov 20
CHS7:00 amCharleston
10h 08m
1 stop
SJO4:08 pmSan José Juan Santamaria Intl
Nov 23
SJO9:55 amSan José Juan Santamaria Intl
6h 15m
1 stop
CHS5:10 pmCharleston
$314
Find similar
JetBlue
Oct 29
CHS5:20 pmCharleston
20h 46m
1 stop
SJO12:06 pmSan José Juan Santamaria Intl
Nov 5
SJO2:01 pmSan José Juan Santamaria Intl
25h 21m
1 stop
CHS4:22 pmCharleston
$316
Find similar
JetBlue
Nov 20
CHS7:00 amCharleston
7h 38m
1 stop
GUA1:38 pmGuatemala City La Aurora
Dec 1
GUA1:56 pmGuatemala City La Aurora
17h 41m
1 stop
CHS8:37 amCharleston
$341
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Charleston to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Sat 11/8

5:40 pm-12:55 am

1 stop8h 15m

Guatemala City La Aurora

Thu 11/13

1:59 am-10:45 am

1 stop7h 46m

$201

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Sat 11/8

5:40 pm-12:26 pm

1 stop19h 46m

Guatemala City La Aurora

Fri 11/14

1:22 pm-10:45 am

1 stop20h 23m

$232

CharlestonLiberia

CHS - LIR

CHSLIR

Charleston

Sat 1/17

5:30 am-11:25 am

1 stop6h 55m

Liberia

Fri 1/23

2:15 pm-11:39 pm

1 stop8h 24m

$265

CharlestonLiberia

CHS - LIR

CHSLIR

Charleston

Sat 1/17

8:39 pm-12:20 pm

1 stop16h 41m

Liberia

Fri 1/23

1:55 pm-10:21 am

2 stops19h 26m

$269

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Sat 11/8

5:40 pm-12:55 am

1 stop8h 15m

Guatemala City La Aurora

Fri 11/14

2:19 pm-10:45 am

2 stops19h 26m

$285

CharlestonSan José

CHS - SJO

CHSSJO

Charleston

Fri 10/24

10:11 am-11:30 am

1 stop27h 19m

San José Juan Santamaria Intl

Mon 10/27

11:37 am-8:37 am

1 stop19h 00m

$286

CharlestonSan José

CHS - SJO

CHSSJO

Charleston

Tue 10/14

6:00 am-12:00 pm

1 stop8h 00m

San José Juan Santamaria Intl

Tue 10/21

2:40 pm-11:59 pm

1 stop7h 19m

$364

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 10/29

6:40 am-12:56 pm

1 stop7h 16m

Panama City Tocumen Intl

Wed 11/26

3:37 pm-10:48 pm

1 stop7h 11m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 10/30

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Thu 11/27

4:41 pm-4:16 pm

1 stop23h 35m

$378

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/16

11:00 am-8:02 pm

1 stop9h 02m

Panama City Tocumen Intl

Sun 2/1

11:55 pm-9:50 am

1 stop9h 55m

$409

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Charleston to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, September is the cheapest month to fly from Charleston to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $435. If you don’t want to visit Central America in September, then you should wait until January to fly from Charleston, when ticket prices are also cheap, with an average price of $452.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Charleston to Central America is on a Wednesday. Travelers who choose to depart for Central America on a Wednesday will often find tickets for as low as $511. On the other hand, Sunday is the most expensive day to depart from Charleston because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $730.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Charleston to Central America flights are usually those with departure times at noon. Our users have found flights to Central America at noon for as low as $463. Try not to purchase tickets in the morning because they tend to be around $576. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Central America?

You are more likely to see cheaper flights to Central America from Charleston when booking weeks ahead of your departure date. In general, you can expect to find flights to Central America for around $554 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Central America from Charleston for as low as $410 on momondo.

Can stopping save me money on Charleston to Central America flights?

You could potentially save up to 10% on your flight if you consider stops on a Charleston to Central America flight.

Cheap Charleston to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Central America

Direct flights

None
There are no direct flights from Charleston to Central America. There are no popular flight routes from Charleston to Central America.
Search flight deals

  • When did momondo last update prices for flights from Charleston Airport to Central America?

    Prices for flights from Charleston Airport to Central America refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Central America?

  • How old do you have to be to fly from Charleston Airport to Central America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charleston to Central America

Compare and see reviews for airlines that fly from Charleston to Central America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $141Free CancellationRating
6.3
8,015 reviews
Search Spirit Airlines flights
DeltaPriceFrom $215Free CancellationRating
7.9
7,954 reviews
Search Delta flights
United AirlinesPriceFrom $332Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
American AirlinesPriceFrom $349Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Charleston to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Charleston to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Charleston with this policy.

How can momondo help me find flights from Charleston to Central America?

momondo helps you find the best flight between Charleston and Central America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charleston to Central America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Central America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Central America and let you know when they change.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

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Popular flights according to clicks in the last 7 days on momondo
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