Find buses from Chicago to Louisville

Because all of the buses from Chicago to Louisville use Greyhound as the operator, you are going to find several great amenities aboard the bus during your travels. Some of the features that you will find on the bus include free Wi-Fi, personal power outlets near the seats, and reclining leather seats that offer extra legroom. There are also no middle seats, so every passenger will ride next to the aisle or with a window view. The buses offer onboard restrooms plus plenty of overhead storage for your baggage.

When you are traveling on buses to Louisville from Chicago aboard Greyhound, you will find that the luggage allowance is generous. You can bring one carry-on bag aboard the bus and store it in the overhead storage area free of charge. For any of your larger baggage, your first bag will travel under the bus free of charge. While you can bring an additional two bags to check under the bus, the second may be subject to an additional fee depending on the bus ticket from Chicago to Louisville that you purchase. The third bag will always incur an additional fee.

As these are two rather large cities in the United States, and due to Louisville being such a popular destination, you are going to find around six different departures every day for buses from Chicago to Louisville. The first departure occurs rather early in the morning at around 6:30 a.m. and then after that, there are departures at around 7:00 a.m., 7:20 a.m., and around 10:30 a.m. There is an afternoon departure at around 4:15 p.m. and then there's an overnight bus that departs at around 10:20 p.m.

All the buses to Louisville from Chicago that operate this route will use the same stations in both cities. When departing from Chicago, you will use the Chicago Downtown Greyhound Station, which is located on Harrison Street at the junction of Interstate 290 and Interstate 90. The Blue Line train can get you to the station from the center of Chicago in around 8min. When you arrive on your Chicago to Louisville bus, you will arrive at the Greyhound Bus Station in Louisville, which is located on Muhamed Ali Boulevard right in the center of Louisville and just blocks from the Ohio River. The 52, 71, and 72 buses can take you from the station to the center of Louisville in around 9min.

Perhaps one of the best parts of buses from Chicago to Louisville is all of the amazing scenery that you can take in while you make the journey. As you depart Chicago and head south on buses to Louisville from Chicago, you will spend quite a bit of time being able to see Lake Michigan out of the left side of the bus. As you continue south along Interstate 65, you will travel through the city of Lafayette before continuing south into the major city of Indianapolis. Along the way, you will be able to soak in all the rolling green fields that the state of Indiana is well known for. As you continue south from Indianapolis, you will pass by the large Brown County State Park before finally crossing the Ohio River and finishing your trip at the station in downtown Louisville.

See available tickets from Chicago to Louisville Intl for this week that start at $85 one-way.

6h 15m is the fastest available option for travel to Louisville Intl from Chicago by bus. Look into Amtrak, they have one of the quickest options available.

You can find bus tickets for Amtrak which service this route currently. Amtrak is the cheapest option recently available with prices starting at $170 round-trip.

The straight-line distance from Chicago to Louisville Intl is 269.2 mi. The actual distance by bus will change based on the roads and any traffic, closures, roadwork or tolls that may impact the driver’s route. The bus journey is around 6h 15m long.