Cheap flights from the United States to Santa Cruz de la Sierra from $285

The cheapest month to fly to Santa Cruz de la Sierra from United States is in April. Flight prices, which tend to average around $641, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in April, then you should wait until March to fly from United States, when ticket prices are also cheap, with an average price of $647.

Fly from Miami to Santa Cruz de la Sierra Viru Viru Intl for the best United States - Santa Cruz de la Sierra Viru Viru Intl flight prices

You are more likely to see cheaper flights to Santa Cruz de la Sierra from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around $841 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from United States for as low as $626 on momondo.

There are 3 cabin classes available to choose from on United States to Santa Cruz de la Sierra flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Copa Airlines, United Airlines, and Avianca are the most popular carriers operating from United States to Santa Cruz de la Sierra Viru Viru Intl

Copa Airlines, BoA and Avianca are the top three most popular airlines that fly to Santa Cruz de la Sierra from United States according to our data. Copa Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Santa Cruz de la Sierra. Keep in mind that there are 5 different airlines that fly to Santa Cruz de la Sierra on a routine basis, so you have a few additional options to choose from.

Historically, on average around 15% of flights between United States and Santa Cruz de la Sierra have experienced a delay on any given week. The average delay length over the past 12 months has been 164 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, BoA have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

The number of flights available between United States and Santa Cruz de la Sierra is 3 per week as of November 2026. The most frequent departure day is Thu, with 33% of weekly flights leaving on this day.

If you’re flying from a popular airport in United States, such as Miami or Boston, and flying into Santa Cruz de la Sierra, then you can expect flight times to average 6h 50m and 12h 09m, respectively.