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Cheap flights from the United States to Panama from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the United States to Panama departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from the United States to Panama

Recent round-trip flight deals from the United States to Panama

Copa Airlines Logo
2:19 pm - 4:25 pmMIA-PTY
3h 06mnonstop
Copa Airlines Logo
3:44 pm - 7:55 pmPTY-MIA
3h 11mnonstop
$276Copa Airlines
Find Deal
Fri, Oct 17 - Wed, Oct 22
Avianca Logo
7:00 am - 2:00 pmMIA-PTY
7h 00m1 stop
Avianca Logo
2:55 am - 11:30 amPTY-MIA
8h 35m1 stop
$277Avianca
Find Deal
Thu, Feb 5 - Sat, Feb 7
American Airlines Logo
12:08 pm - 2:03 pmMIA-PTY
2h 55mnonstop
American Airlines Logo
3:15 pm - 7:25 pmPTY-MIA
3h 10mnonstop
$302American Airlines
Find Deal
Mon, Oct 27 - Thu, Oct 30
Multiple Airlines Logo
11:54 am - 1:00 amATL-PTY
14h 06m2 stops
Multiple Airlines Logo
2:55 am - 6:12 pmPTY-ATL
15h 17m2 stops
$370Multiple Airlines
Find Deal
Sat, Nov 1 - Mon, Dec 8
Multiple Airlines Logo
10:05 am - 12:10 amEWR-PTY
15h 05m2 stops
Multiple Airlines Logo
3:20 am - 11:29 pmPTY-EWR
19h 09m2 stops
$381Multiple Airlines
Find Deal
Tue, Oct 21 - Thu, Oct 23
Delta Logo
9:50 am - 12:56 pmATL-PTY
4h 06mnonstop
Delta Logo
3:21 pm - 7:37 pmPTY-ATL
4h 16mnonstop
$391Delta
Find Deal
Sun, Oct 12 - Tue, Nov 4
American Airlines Logo
7:00 am - 1:49 pmATL-PTY
6h 49m1 stop
American Airlines Logo
2:49 pm - 11:59 pmPTY-ATL
9h 10m1 stop
$405American Airlines
Find Deal
Tue, Nov 11 - Sat, Nov 15
United Airlines Logo
7:00 am - 5:07 pmMCO-PTY
10h 07m1 stop
United Airlines Logo
4:41 pm - 11:54 amPTY-MCO
19h 13m1 stop
$416United Airlines
Find Deal
Fri, Jan 16 - Tue, Jan 20
United Airlines Logo
9:00 am - 5:07 pmMCO-PTY
8h 07m1 stop
United Airlines Logo
7:55 am - 9:50 pmPTY-MCO
12h 55m1 stop
$425United Airlines
Find Deal
Sat, Jan 31 - Thu, Apr 9
Delta Logo
9:50 am - 12:56 pmATL-PTY
4h 06mnonstop
Delta Logo
3:21 pm - 7:37 pmPTY-ATL
4h 16mnonstop
$447Delta
Find Deal
Wed, Oct 15 - Wed, Nov 5

Avianca flights from United States to Panama

Our best Avianca deals on United States to Panama flight tickets
Avianca
Feb 5
MIA7:00 amMiami
7h 00m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Feb 7
PTY2:55 amPanama City Tocumen Intl
8h 35m
1 stop
MIA11:30 amMiami
$277
Find similar
Avianca
Nov 9
MIA5:10 amMiami
13h 45m
1 stop
PTY6:55 pmPanama City Tocumen Intl
Nov 15
PTY2:55 amPanama City Tocumen Intl
8h 35m
1 stop
MIA11:30 amMiami
$278
Find similar
Avianca
Oct 17
MIA5:35 amMiami
8h 00m
2 stops
PTY12:35 pmPanama City Tocumen Intl
Oct 26
PTY2:55 amPanama City Tocumen Intl
14h 10m
1 stop
MIA6:05 pmMiami
$279
Find similar

American Airlines flights from United States to Panama

Our best American Airlines deals on United States to Panama flight tickets
American Airlines
Oct 27
MIA12:08 pmMiami
2h 55m
PTY2:03 pmPanama City Tocumen Intl
Oct 30
PTY3:15 pmPanama City Tocumen Intl
3h 10m
MIA7:25 pmMiami
$302
Find similar
American Airlines
Oct 8
MIA12:08 pmMiami
2h 55m
PTY2:03 pmPanama City Tocumen Intl
Oct 12
PTY3:15 pmPanama City Tocumen Intl
3h 10m
MIA7:25 pmMiami
$321
Find similar
American Airlines
Oct 8
MIA12:08 pmMiami
2h 55m
PTY2:03 pmPanama City Tocumen Intl
Oct 31
PTY3:15 pmPanama City Tocumen Intl
3h 10m
MIA7:25 pmMiami
$364
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from United States to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 28, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 10/17

2:19 pm-4:25 pm

Nonstop3h 06m

Panama City Tocumen Intl

Wed 10/22

3:44 pm-7:55 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 2/5

7:00 am-2:00 pm

1 stop7h 00m

Panama City Tocumen Intl

Sat 2/7

2:55 am-11:30 am

1 stop8h 35m

$277

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Mon 10/27

12:08 pm-2:03 pm

Nonstop2h 55m

Panama City Tocumen Intl

Thu 10/30

3:15 pm-7:25 pm

Nonstop3h 10m

$302

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Sat 11/1

11:54 am-1:00 am

2 stops14h 06m

Panama City Tocumen Intl

Mon 12/8

2:55 am-6:12 pm

2 stops15h 17m

$370

NewarkPanama City

EWR - PTY

EWRPTY

Newark

Tue 10/21

10:05 am-12:10 am

2 stops15h 05m

Panama City Tocumen Intl

Thu 10/23

3:20 am-11:29 pm

2 stops19h 09m

$381

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Sun 10/12

9:50 am-12:56 pm

Nonstop4h 06m

Panama City Tocumen Intl

Tue 11/4

3:21 pm-7:37 pm

Nonstop4h 16m

$391

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Tue 11/11

7:00 am-1:49 pm

1 stop6h 49m

Panama City Tocumen Intl

Sat 11/15

2:49 pm-11:59 pm

1 stop9h 10m

$405

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Fri 1/16

7:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-11:54 am

1 stop19h 13m

$416

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Sat 1/31

9:00 am-5:07 pm

1 stop8h 07m

Panama City Tocumen Intl

Thu 4/9

7:55 am-9:50 pm

1 stop12h 55m

$425

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Wed 10/15

9:50 am-12:56 pm

Nonstop4h 06m

Panama City Tocumen Intl

Wed 11/5

3:21 pm-7:37 pm

Nonstop4h 16m

$447

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Panama from

How to get the cheapest flight ticket from United States to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from United States, with most prices found around $484. If you don’t want to visit Panama in October, then you should wait until September to fly from United States, when ticket prices are also cheap, with an average price of $494.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from United States. The lowest ticket price found for a Wednesday departure recently was $614. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from United States to Panama for around $655.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from United States to Panama when you can find flight prices for as low as $339. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $634 per ticket.

What is the cheapest United States to Panama flight route?

Fly from Boston Logan Intl to Panama City Tocumen Intl for the best United States - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $593 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from United States for as low as $526 on momondo.

What cabin class options are available on United States to Panama flights?

There are 3 cabin classes available to choose from on United States to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on United States to Panama flights?

You could potentially save up to 12% on your flight if you consider stops on a United States to Panama flight.

Cheap United States to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from United States to Panama

Best Price Found

$130

Fastest flight time

2h 55m

Direct flights

Every day

Airports in Panama

1 airport
The best one-way flight to Panama from United States in the past 72 hours is $130. The best round-trip flight deal from United States to Panama found on momondo in the last 72 hours is $285.
The fastest flight from United States to Panama takes 2h 55m
Direct flights go from United States to Panama every day.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from United States to Panama?

    Prices for flights from United States to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from United States to Panama?

  • How old do you have to be to fly from United States to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from United States to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from United States to Panama?

Best airlines flying from United States to Panama

Compare and see reviews for airlines that fly from United States to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $132Free CancellationRating
6.7
2,444 reviews
Search Avianca flights
DeltaPriceFrom $147Free CancellationRating
7.9
7,973 reviews
Search Delta flights
American AirlinesPriceFrom $203Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $226Free CancellationRating
7.6
1,539 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $290Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from United States to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from United States to Panama for you.

Can I find flights from United States to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for United States to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from United States to Panama?

momondo helps you find the best flight between United States and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from United States to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from United States and alert you when they change.

An easier way to manage your Panama trip

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