Cheap flights from the United States to Panama from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the United States to Panama departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from the United States to Panama

Recent round-trip flight deals from the United States to Panama

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Copa Airlines Logo
5:34 am - 8:40 amMIA-PTY
3h 06mnonstop
Copa Airlines Logo
6:11 pm - 9:22 pmPTY-MIA
3h 11mnonstop
$276Copa Airlines
Find Deal
Sat, Dec 6 - Tue, Dec 9
Avianca Logo
2:05 am - 8:50 amMIA-PTY
6h 45m1 stop
Avianca Logo
2:55 am - 11:30 amPTY-MIA
8h 35m1 stop
$277Avianca
Find Deal
Thu, Jan 29 - Sat, Jan 31
Avianca Logo
7:05 am - 6:55 pmMIA-PTY
11h 50m1 stop
Avianca Logo
2:55 pm - 3:10 amPTY-MIA
12h 15m1 stop
$279Avianca
Find Deal
Thu, Jan 15 - Mon, Jan 19
American Airlines Logo
10:25 am - 1:47 pmMIA-PTY
3h 22mnonstop
American Airlines Logo
4:43 pm - 8:00 pmPTY-MIA
3h 17mnonstop
$281American Airlines
Find Deal
Mon, Dec 8 - Sun, Dec 14
American Airlines Logo
7:30 am - 3:38 pmEWR-PTY
8h 08m1 stop
American Airlines Logo
4:50 pm - 12:59 amPTY-EWR
8h 09m1 stop
$332American Airlines
Find Deal
Mon, Feb 2 - Thu, Feb 5
Multiple Airlines Logo
10:55 pm - 8:06 amATL-PTY
9h 11m1 stop
Multiple Airlines Logo
9:33 pm - 7:48 amPTY-ATL
10h 15m1 stop
$395Multiple Airlines
Find Deal
Fri, Feb 13 - Wed, Feb 18
Multiple Airlines Logo
9:57 am - 12:40 amATL-PTY
14h 43m2 stops
Multiple Airlines Logo
5:50 pm - 9:02 amPTY-ATL
15h 12m2 stops
$398Multiple Airlines
Find Deal
Wed, Jan 21 - Tue, Jan 27
United Airlines Logo
8:15 am - 5:07 pmIAD-PTY
8h 52m1 stop
United Airlines Logo
4:41 pm - 11:26 amPTY-IAD
18h 45m1 stop
$473United Airlines
Find Deal
Wed, Feb 11 - Mon, Feb 16
Delta Logo
6:00 am - 2:02 pmLGA-PTY
8h 02m1 stop
Delta Logo
2:20 pm - 11:44 pmPTY-LGA
8h 24m1 stop
$562Delta
Find Deal
Sun, Mar 1 - Tue, Mar 31
Delta Logo
5:35 am - 1:55 pmHOU-PTY
7h 20m1 stop
Delta Logo
3:20 pm - 10:35 pmPTY-HOU
8h 15m1 stop
$754Delta
Find Deal
Tue, Jan 13 - Wed, Jan 21

American Airlines flights from United States to Panama

Our best American Airlines deals on United States to Panama flight tickets
American Airlines
Dec 8
MIA10:25 amMiami
3h 22m
PTY1:47 pmPanama City Tocumen Intl
Dec 14
PTY4:43 pmPanama City Tocumen Intl
3h 17m
MIA8:00 pmMiami
American Airlines
Jan 12
MIA12:26 pmMiami
3h 12m
PTY3:38 pmPanama City Tocumen Intl
Jan 15
PTY4:50 pmPanama City Tocumen Intl
3h 13m
MIA8:03 pmMiami
American Airlines
Feb 2
EWR7:30 amNewark
8h 08m
1 stop
PTY3:38 pmPanama City Tocumen Intl
Feb 5
PTY4:50 pmPanama City Tocumen Intl
8h 09m
1 stop
EWR12:59 amNewark

Delta flights from United States to Panama

Our best Delta deals on United States to Panama flight tickets
Delta
Feb 18
ATL9:51 amAtlanta Hartsfield-Jackson
4h 11m
PTY2:02 pmPanama City Tocumen Intl
Mar 4
PTY3:27 pmPanama City Tocumen Intl
4h 22m
ATL7:49 pmAtlanta Hartsfield-Jackson
Delta
Nov 14
ATL10:04 amAtlanta Hartsfield-Jackson
4h 08m
PTY2:12 pmPanama City Tocumen Intl
Nov 17
PTY3:37 pmPanama City Tocumen Intl
4h 18m
ATL7:55 pmAtlanta Hartsfield-Jackson
Delta
Mar 1
LGA6:00 amNew York LaGuardia
8h 02m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Mar 31
PTY2:20 pmPanama City Tocumen Intl
8h 24m
1 stop
LGA11:44 pmNew York LaGuardia

momondo Fare Finder

 
Customize your flight search to find flights from United States to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 14, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sat 12/6

5:34 am-8:40 am

Nonstop3h 06m

Panama City Tocumen Intl

Tue 12/9

6:11 pm-9:22 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 1/29

2:05 am-8:50 am

1 stop6h 45m

Panama City Tocumen Intl

Sat 1/31

2:55 am-11:30 am

1 stop8h 35m

$277

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 1/15

7:05 am-6:55 pm

1 stop11h 50m

Panama City Tocumen Intl

Mon 1/19

2:55 pm-3:10 am

1 stop12h 15m

$279

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Mon 12/8

10:25 am-1:47 pm

Nonstop3h 22m

Panama City Tocumen Intl

Sun 12/14

4:43 pm-8:00 pm

Nonstop3h 17m

$281

NewarkPanama City

EWR - PTY

EWRPTY

Newark

Mon 2/2

7:30 am-3:38 pm

1 stop8h 08m

Panama City Tocumen Intl

Thu 2/5

4:50 pm-12:59 am

1 stop8h 09m

$332

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Fri 2/13

10:55 pm-8:06 am

1 stop9h 11m

Panama City Tocumen Intl

Wed 2/18

9:33 pm-7:48 am

1 stop10h 15m

$395

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Wed 1/21

9:57 am-12:40 am

2 stops14h 43m

Panama City Tocumen Intl

Tue 1/27

5:50 pm-9:02 am

2 stops15h 12m

$398

Washington, D.C.Panama City

IAD - PTY

IADPTY

Washington, D.C. Dulles Intl

Wed 2/11

8:15 am-5:07 pm

1 stop8h 52m

Panama City Tocumen Intl

Mon 2/16

4:41 pm-11:26 am

1 stop18h 45m

$473

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 3/1

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 3/31

2:20 pm-11:44 pm

1 stop8h 24m

$562

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 1/13

5:35 am-1:55 pm

1 stop7h 20m

Panama City Tocumen Intl

Wed 1/21

3:20 pm-10:35 pm

1 stop8h 15m

$754

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Panama from

How to get the cheapest flight ticket from United States to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from United States, with most prices found around $528. If you don’t want to visit Panama in September, then you should wait until June to fly from United States, when ticket prices are also cheap, with an average price of $553.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from United States. The lowest ticket price found for a Wednesday departure recently was $606. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from United States to Panama for around $656.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from United States to Panama when you can find flight prices for as low as $339. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $628 per ticket.

What is the cheapest United States to Panama flight route?

Fly from Boston Logan Intl to Panama City Tocumen Intl for the best United States - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $614 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from United States for as low as $541 on momondo.

What cabin class options are available on United States to Panama flights?

There are 3 cabin classes available to choose from on United States to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on United States to Panama flights?

You could potentially save up to 26% on your flight if you consider stops on a United States to Panama flight.

Cheap United States to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from United States to Panama

Best Price Found

$148

Fastest flight time

3h 04m

Direct flights

Every day

Airports in Panama

1 airport
The best one-way flight to Panama from United States in the past 72 hours is $148. The best round-trip flight deal from United States to Panama found on momondo in the last 72 hours is $296.
The fastest flight from United States to Panama takes 3h 04m
Direct flights go from United States to Panama every day.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
  • When did momondo last update prices for flights from United States to Panama?

    Prices for flights from United States to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from United States to Panama?

  • How old do you have to be to fly from United States to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from United States to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from United States to Panama?

Best airlines flying from United States to Panama

Compare and see reviews for airlines that fly from United States to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $136Free CancellationRating
6.6
2,476 reviews
Search Avianca flights
DeltaPriceFrom $147Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $203Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $230Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $290Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from United States to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from United States to Panama for you.

Can I find flights from United States to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for United States to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from United States to Panama?

momondo helps you find the best flight between United States and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from United States to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from United States and alert you when they change.

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1 adult
Sun 12/14
Sun 12/21

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