Cheap flights from Syracuse to Chicago from $131

The month of January is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Syracuse averaging around $326.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $449. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Syracuse because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $635.

Flying to Chicago O'Hare Intl Airport from Syracuse in the evening is the least expensive time of day to depart. momondo users have found prices as low as $436 when looking at flights departing in the evening. Try not to purchase tickets in the morning because they tend to be around $500. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Syracuse Hancock Intl to Chicago O'Hare Intl for the best Syracuse Hancock Intl - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $364 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Syracuse for as low as $268 on momondo.

There are 4 cabin classes available to choose from on Syracuse to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Syracuse to Chicago O'Hare Intl Airport.

As of November 2026, prices for Syracuse to Chicago O'Hare Intl Airport flights are approximately 21% cheaper when compared to flights at the same time last year.

American Airlines and United Airlines are the most popular carriers operating from Syracuse Hancock Intl to Chicago O'Hare Intl

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Syracuse according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 3 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

As of November 2026, 22 flights take off from Syracuse and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 12:00PM, with 58% of daily flights taking off in the afternoon.

As of November 2026, there are 160 flights per week flying from Syracuse to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Mon, with 15% of flights taking off on this day.