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Cheap flights from St. Louis to the Cayman Islands from $342

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to the Cayman Islands departing on 5/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from St. Louis to the Cayman Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:54 pm - 11:00 am
STL
-
GCM
16h 06m
2 stops
American Airlines Logo
12:33 pm - 7:00 pm
GCM
-
STL
6h 27m
1 stop
$342American Airlines
Sun, May 17 - Fri, May 22
Delta Logo
6:00 am - 12:00 pm
STL
-
GCM
6h 00m
1 stop
Delta Logo
1:25 pm - 9:19 pm
GCM
-
STL
7h 54m
1 stop
$357Delta
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:54 pm - 1:10 pm
STL
-
GCM
18h 16m
2 stops
American Airlines Logo
12:33 pm - 7:00 pm
GCM
-
STL
6h 27m
1 stop
$362American Airlines
Sun, May 17 - Fri, May 22
United Airlines Logo
8:15 pm - 1:30 pm
STL
-
GCM
17h 15m
1 stop
United Airlines Logo
1:50 pm - 9:13 pm
GCM
-
STL
7h 23m
1 stop
$392United Airlines
Fri, Apr 10 - Mon, Apr 13
United Airlines Logo
8:15 pm - 12:30 pm
STL
-
GCM
16h 15m
2 stops
United Airlines Logo
1:50 pm - 9:13 pm
GCM
-
STL
7h 23m
1 stop
$397United Airlines
Fri, Apr 10 - Mon, Apr 13
Air Canada Logo
1:00 pm - 11:25 am
STL
-
GCM
46h 25m
2 stops
Air Canada Logo
10:55 am - 12:06 pm
GCM
-
STL
25h 11m
1 stop
$419Air Canada
Sat, Jun 6 - Sat, Jun 13
American Airlines Logo
6:54 pm - 11:31 am
STL
-
GCM
16h 37m
1 stop
American Airlines Logo
2:42 pm - 11:59 pm
GCM
-
STL
9h 17m
1 stop
$437American Airlines
Sun, May 17 - Fri, May 22
American Airlines Logo
5:24 am - 11:00 am
STL
-
GCM
5h 36m
1 stop
American Airlines Logo
12:35 pm - 7:30 pm
GCM
-
STL
6h 55m
1 stop
$467American Airlines
Sun, May 10 - Thu, May 14
Delta Logo
6:00 am - 11:54 am
STL
-
GCM
5h 54m
1 stop
Delta Logo
1:19 pm - 11:59 pm
GCM
-
STL
10h 40m
1 stop
$468Delta
Tue, May 26 - Tue, Jun 2
United Airlines Logo
8:30 pm - 12:30 pm
STL
-
GCM
16h 00m
2 stops
United Airlines Logo
1:35 pm - 8:41 am
GCM
-
STL
19h 06m
2 stops
$472United Airlines
Sun, May 17 - Fri, May 22

American Airlines flights from St. Louis to Cayman Islands

Our best American Airlines deals on St. Louis to Cayman Islands flight tickets
American Airlines
May 17
STL6:54 pmLambert-St Louis
16h 06m
2 stops
GCM11:00 amGeorge Town Owen Roberts Intl
May 22
GCM12:33 pmGeorge Town Owen Roberts Intl
6h 27m
1 stop
STL7:00 pmLambert-St Louis
$342
American Airlines
May 17
STL6:54 pmLambert-St Louis
18h 16m
2 stops
GCM1:10 pmGeorge Town Owen Roberts Intl
May 22
GCM12:33 pmGeorge Town Owen Roberts Intl
6h 27m
1 stop
STL7:00 pmLambert-St Louis
$362
American Airlines
May 17
STL6:54 pmLambert-St Louis
16h 37m
1 stop
GCM11:31 amGeorge Town Owen Roberts Intl
May 22
GCM2:42 pmGeorge Town Owen Roberts Intl
9h 17m
1 stop
STL11:59 pmLambert-St Louis
$437

Delta flights from St. Louis to Cayman Islands

Our best Delta deals on St. Louis to Cayman Islands flight tickets
Delta
Apr 21
STL6:00 amLambert-St Louis
6h 00m
1 stop
GCM12:00 pmGeorge Town Owen Roberts Intl
Apr 28
GCM1:25 pmGeorge Town Owen Roberts Intl
7h 54m
1 stop
STL9:19 pmLambert-St Louis
$357
Delta
May 26
STL6:00 amLambert-St Louis
5h 54m
1 stop
GCM11:54 amGeorge Town Owen Roberts Intl
Jun 2
GCM1:19 pmGeorge Town Owen Roberts Intl
10h 40m
1 stop
STL11:59 pmLambert-St Louis
$468
Delta
May 17
STL6:00 amLambert-St Louis
5h 54m
1 stop
GCM11:54 amGeorge Town Owen Roberts Intl
May 22
GCM1:19 pmGeorge Town Owen Roberts Intl
10h 40m
1 stop
STL11:59 pmLambert-St Louis
$506

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 5/17

6:54 pm-11:00 am

2 stops16h 06m

George Town Owen Roberts Intl

Fri 5/22

12:33 pm-7:00 pm

1 stop6h 27m

$342

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 4/21

6:00 am-12:00 pm

1 stop6h 00m

George Town Owen Roberts Intl

Tue 4/28

1:25 pm-9:19 pm

1 stop7h 54m

$357

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 5/17

6:54 pm-1:10 pm

2 stops18h 16m

George Town Owen Roberts Intl

Fri 5/22

12:33 pm-7:00 pm

1 stop6h 27m

$362

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 4/10

8:15 pm-1:30 pm

1 stop17h 15m

George Town Owen Roberts Intl

Mon 4/13

1:50 pm-9:13 pm

1 stop7h 23m

$392

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 4/10

8:15 pm-12:30 pm

2 stops16h 15m

George Town Owen Roberts Intl

Mon 4/13

1:50 pm-9:13 pm

1 stop7h 23m

$397

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 6/6

1:00 pm-11:25 am

2 stops46h 25m

George Town Owen Roberts Intl

Sat 6/13

10:55 am-12:06 pm

1 stop25h 11m

$419

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 5/17

6:54 pm-11:31 am

1 stop16h 37m

George Town Owen Roberts Intl

Fri 5/22

2:42 pm-11:59 pm

1 stop9h 17m

$437
Quickest round-trip

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 5/10

5:24 am-11:00 am

1 stop5h 36m

George Town Owen Roberts Intl

Thu 5/14

12:35 pm-7:30 pm

1 stop6h 55m

$467

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 5/26

6:00 am-11:54 am

1 stop5h 54m

George Town Owen Roberts Intl

Tue 6/2

1:19 pm-11:59 pm

1 stop10h 40m

$468

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 5/17

8:30 pm-12:30 pm

2 stops16h 00m

George Town Owen Roberts Intl

Fri 5/22

1:35 pm-8:41 am

2 stops19h 06m

$472

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to the Cayman Islands from

How to get the cheapest flight ticket from St. Louis to Cayman Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cayman Islands?

If you aren’t able to travel to Cayman Islands during the month of September, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $537.

How far in advance should I book a flight to Cayman Islands?

You are more likely to see cheaper flights to Cayman Islands from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Cayman Islands for around $592 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cayman Islands from St. Louis for as low as $471 on momondo.

Cheap St. Louis to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Cayman Islands

Fastest flight time

5h 47m

Direct flights

None
The fastest flight from St. Louis to Cayman Islands takes 5h 47m
There are no direct flights from St. Louis to Cayman Islands. There are no popular flight routes from St. Louis to Cayman Islands.
Search flight deals

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Cayman Islands?

    Prices for flights from Lambert-St Louis Airport to Cayman Islands were last updated today.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Cayman Islands?

  • How old do you have to be to fly from Lambert-St Louis Airport to Cayman Islands?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Lambert-St Louis Airport to Cayman Islands.

  • What documentation or ID do you need to fly to Cayman Islands?

    The necessary travel and health documents for your Cayman Islands trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from St. Louis to Cayman Islands

Compare and see reviews for airlines that fly from St. Louis to Cayman Islands with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $190Free CancellationRating
7.9
8,291 reviews
Search Delta flights
United AirlinesPriceFrom $364Free CancellationRating
7.4
9,423 reviews
Search United Airlines flights
SouthwestPriceFrom $429Free CancellationRating
8.0
4,317 reviews
Search Southwest flights
American AirlinesPriceFrom $446Free CancellationRating
7.1
11,464 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Cayman Islands?

It is quick and easy to find St. Louis to Cayman Islands flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cayman Islands that suits you.

Can I find flights from St. Louis to Cayman Islands with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Cayman Islands from St. Louis with this policy.

How can momondo help me find flights from St. Louis to Cayman Islands?

momondo helps you find the best flight between St. Louis and Cayman Islands by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from St. Louis to Cayman Islands right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of St. Louis to Cayman Islands flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to the Cayman Islands

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