Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Palermo from $599

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Palermo departing on 11/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Palermo

Cheap round-trip flights

Multiple Airlines Logo
6:50 pm - 6:25 pmCLT-PMO
17h 35m2 stops
Multiple Airlines Logo
6:25 pm - 4:55 pmPMO-CLT
28h 30m1 stop
$706Multiple Airlines
Find Deal
Sun, Nov 9 - Sun, Nov 16
Multiple Airlines Logo
6:50 pm - 6:25 pmCLT-PMO
17h 35m2 stops
Multiple Airlines Logo
12:10 pm - 4:55 pmPMO-CLT
34h 45m1 stop
$712Multiple Airlines
Find Deal
Sun, Feb 15 - Sat, Feb 21
KLM Logo
11:01 am - 6:20 pmCAE-PMO
25h 19m2 stops
KLM Logo
2:25 pm - 6:59 pmPMO-CAE
34h 34m2 stops
$880KLM
Find Deal
Fri, Nov 14 - Tue, Nov 18
KLM Logo
11:01 am - 11:00 pmCAE-PMO
29h 59m2 stops
KLM Logo
12:25 pm - 6:59 pmPMO-CAE
60h 34m2 stops
$886KLM
Find Deal
Fri, Nov 14 - Tue, Nov 18
Air Canada Logo
9:30 am - 11:40 amCLT-PMO
20h 10m3 stops
Air Canada Logo
10:00 am - 4:17 pmPMO-CLT
36h 17m3 stops
$924Air Canada
Find Deal
Fri, Nov 28 - Sun, Dec 7
Air Canada Logo
9:30 am - 11:25 amCLT-PMO
19h 55m2 stops
Air Canada Logo
10:00 am - 4:17 pmPMO-CLT
36h 17m3 stops
$930Air Canada
Find Deal
Fri, Nov 28 - Sun, Dec 7
SWISS Logo
6:40 pm - 11:25 pmCLT-PMO
22h 45m2 stops
SWISS Logo
5:50 am - 9:41 pmPMO-CLT
21h 51m2 stops
$1,056SWISS
Find Deal
Fri, Oct 3 - Tue, Oct 7
Lufthansa Logo
6:40 pm - 5:25 pmCLT-PMO
16h 45m1 stop
Lufthansa Logo
5:55 pm - 4:45 pmPMO-CLT
28h 50m1 stop
$1,265Lufthansa
Find Deal
Sat, Oct 4 - Tue, Oct 14
Lufthansa Logo
2:54 pm - 11:25 amCLT-PMO
14h 31m2 stops
Lufthansa Logo
6:25 pm - 4:55 pmPMO-CLT
28h 30m1 stop
$1,425Lufthansa
Find Deal
Fri, Dec 19 - Sun, Jan 11
SWISS Logo
6:50 pm - 6:25 pmCLT-PMO
17h 35m2 stops
SWISS Logo
7:55 pm - 4:55 pmPMO-CLT
27h 00m2 stops
$1,522SWISS
Find Deal
Sun, Dec 21 - Sat, Dec 27

Lufthansa flights from South Carolina to Palermo

Our best Lufthansa deals on South Carolina to Palermo flight tickets
Lufthansa
Oct 4
CLT6:40 pmCharlotte Douglas
16h 45m
1 stop
PMO5:25 pmPalermo Punta Raisi
Oct 14
PMO5:55 pmPalermo Punta Raisi
28h 50m
1 stop
CLT4:45 pmCharlotte Douglas
$1,265
Find similar
Lufthansa
Dec 19
CLT2:54 pmCharlotte Douglas
14h 31m
2 stops
PMO11:25 amPalermo Punta Raisi
Jan 11
PMO6:25 pmPalermo Punta Raisi
28h 30m
1 stop
CLT4:55 pmCharlotte Douglas
$1,425
Find similar
Lufthansa
Dec 19
CLT2:54 pmCharlotte Douglas
14h 31m
2 stops
PMO11:25 amPalermo Punta Raisi
Jan 11
PMO10:00 amPalermo Punta Raisi
36h 55m
2 stops
CLT4:55 pmCharlotte Douglas
$1,434
Find similar

SWISS flights from South Carolina to Palermo

Our best SWISS deals on South Carolina to Palermo flight tickets
SWISS
Oct 3
CLT6:40 pmCharlotte Douglas
22h 45m
2 stops
PMO11:25 pmPalermo Punta Raisi
Oct 7
PMO5:50 amPalermo Punta Raisi
21h 51m
2 stops
CLT9:41 pmCharlotte Douglas
$1,056
Find similar
SWISS
Dec 21
CLT6:50 pmCharlotte Douglas
17h 35m
2 stops
PMO6:25 pmPalermo Punta Raisi
Dec 27
PMO7:55 pmPalermo Punta Raisi
27h 00m
2 stops
CLT4:55 pmCharlotte Douglas
$1,522
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sun 11/16

6:25 pm-4:55 pm

1 stop28h 30m

$706

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/15

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/21

12:10 pm-4:55 pm

1 stop34h 45m

$712

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Fri 11/14

11:01 am-6:20 pm

2 stops25h 19m

Palermo Punta Raisi

Tue 11/18

2:25 pm-6:59 pm

2 stops34h 34m

$880

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Fri 11/14

11:01 am-11:00 pm

2 stops29h 59m

Palermo Punta Raisi

Tue 11/18

12:25 pm-6:59 pm

2 stops60h 34m

$886

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Fri 11/28

9:30 am-11:40 am

3 stops20h 10m

Palermo Punta Raisi

Sun 12/7

10:00 am-4:17 pm

3 stops36h 17m

$924

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Fri 11/28

9:30 am-11:25 am

2 stops19h 55m

Palermo Punta Raisi

Sun 12/7

10:00 am-4:17 pm

3 stops36h 17m

$930

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Fri 10/3

6:40 pm-11:25 pm

2 stops22h 45m

Palermo Punta Raisi

Tue 10/7

5:50 am-9:41 pm

2 stops21h 51m

$1,056

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sat 10/4

6:40 pm-5:25 pm

1 stop16h 45m

Palermo Punta Raisi

Tue 10/14

5:55 pm-4:45 pm

1 stop28h 50m

$1,265

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Fri 12/19

2:54 pm-11:25 am

2 stops14h 31m

Palermo Punta Raisi

Sun 1/11

6:25 pm-4:55 pm

1 stop28h 30m

$1,425

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 12/21

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 12/27

7:55 pm-4:55 pm

2 stops27h 00m

$1,522

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

See travel insights to Palermo from

How to get the cheapest flight ticket from South Carolina to Palermo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Palermo?

The cheapest month to fly to Palermo from South Carolina is in February. Flight prices, which tend to average around $711, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Palermo from South Carolina during November instead. Flights to Palermo in November, while not as cheap as those in February, still average around $743.

What is the cheapest day to depart on your flight to Palermo?

The cheapest day to depart from South Carolina to Palermo is on a Wednesday when prices can be found for as low as $868. On the other hand, Monday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,326.

What is the cheapest time of day to depart on your flight to Palermo?

Our data shows that the cheapest South Carolina to Palermo flights are usually those with departure times in the evening. Our users have found flights to Palermo in the evening for as low as $1,109. Flights at noon are often more expensive with an average ticket price of $1,416.

Cheap South Carolina to Palermo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Palermo

Direct flights

None
There are no direct flights from South Carolina to Palermo. There are no popular flight routes from South Carolina to Palermo.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Palermo Punta Raisi Airport?

    Prices for flights from South Carolina to Palermo Punta Raisi Airport are refreshed on a daily basis.

  • How old do you have to be to fly from South Carolina to Palermo Punta Raisi Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Palermo Punta Raisi Airport.

  • What documentation or ID do you need to fly to Palermo Punta Raisi Airport?

    The necessary travel and health documents for your Palermo Punta Raisi Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Palermo

Compare and see reviews for airlines that fly from South Carolina to Palermo with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $861Free CancellationRating
6.8
7,415 reviews
Search Lufthansa flights

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Cefalù
San Vito Lo Capo
Agrigento
Castellammare del Golfo
Sciacca
Scopello
Alcamo
Ustica

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Palermo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Palermo from South Carolina.

Can I find flights from South Carolina to Palermo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Palermo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Palermo?

Once all potential South Carolina to Palermo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Palermo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Palermo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Palermo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 10/19
Sun 10/26
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Italy