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Cheap flights from South Carolina to Palermo from $392

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Palermo departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Palermo

Cheap round-trip flights

Enter your travel dates to find the best prices.
KLM Logo
11:27 am - 2:20 pmMYR  Myrtle Beach Intl-PMO Palermo Punta Raisi
21h 53m2 stops Detroit Metropolitan Wayne County Rome Fiumicino
KLM Logo
6:10 am - 6:06 pmPMO  Palermo Punta Raisi-MYR Myrtle Beach Intl
41h 56m2 stops Rome Fiumicino Atlanta Hartsfield-Jackson
$792KLM
Wed, Oct 28 - Thu, Nov 12
Lufthansa Logo
11:27 am - 12:20 pmMYR  Myrtle Beach Intl-PMO Palermo Punta Raisi
19h 53m1 stop Newark
Lufthansa Logo
2:20 pm - 10:21 amPMO  Palermo Punta Raisi-MYR Myrtle Beach Intl
26h 01m1 stop Newark
$810Lufthansa
Wed, Oct 28 - Thu, Nov 12
Lufthansa Logo
11:27 am - 11:00 amMYR  Myrtle Beach Intl-PMO Palermo Punta Raisi
18h 33m2 stops Newark Munich Franz Josef Strauss
Lufthansa Logo
2:20 pm - 10:21 amPMO  Palermo Punta Raisi-MYR Myrtle Beach Intl
26h 01m1 stop Newark
$818Lufthansa
Wed, Oct 28 - Thu, Nov 12
Multiple Airlines Logo
6:50 pm - 11:55 pmCLT  Charlotte Douglas-PMO Palermo Punta Raisi
23h 05m2 stops Munich Franz Josef Strauss Milan Malpensa
Multiple Airlines Logo
6:15 am - 4:55 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
40h 40m2 stops Milan Malpensa Munich Franz Josef Strauss
$839Multiple Airlines
Sat, Jan 9 - Wed, Jan 20
Multiple Airlines Logo
7:47 pm - 11:25 amCLT  Charlotte Douglas-PMO Palermo Punta Raisi
33h 38m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Multiple Airlines Logo
2:45 pm - 4:55 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
56h 10m2 stops Zurich Munich Franz Josef Strauss
$898Multiple Airlines
Wed, Dec 2 - Sun, Dec 6
SWISS Logo
6:40 pm - 6:40 pmCLT  Charlotte Douglas-PMO Palermo Punta Raisi
18h 00m2 stops Munich Franz Josef Strauss Zurich
SWISS Logo
9:45 am - 9:15 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
17h 30m2 stops Zurich Chicago O'Hare Intl
$917SWISS
Tue, Sep 22 - Tue, Sep 29
Air France Logo
2:28 pm - 11:30 amCLT  Charlotte Douglas-PMO Palermo Punta Raisi
15h 02m2 stops New York John F Kennedy Intl Rome Fiumicino
Air France Logo
10:05 am - 11:54 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
19h 49m2 stops Rome Fiumicino Atlanta Hartsfield-Jackson
$920Air France
Wed, Nov 4 - Wed, Nov 11
Lufthansa Logo
7:47 pm - 11:25 amCLT  Charlotte Douglas-PMO Palermo Punta Raisi
33h 38m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
6:30 pm - 4:55 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
28h 25m1 stop Munich Franz Josef Strauss
$927Lufthansa
Wed, Dec 2 - Sun, Dec 6
Multiple Airlines Logo
6:40 pm - 11:50 pmCLT  Charlotte Douglas-PMO Palermo Punta Raisi
23h 10m2 stops Munich Franz Josef Strauss Milan Malpensa
Multiple Airlines Logo
11:40 pm - 8:57 pmPMO  Palermo Punta Raisi-CLT Charlotte Douglas
27h 17m3 stops Milan Malpensa Frankfurt am Main Toronto Pearson Intl
$938Multiple Airlines
Sun, Sep 6 - Mon, Sep 14
United Airlines Logo
3:20 pm - 12:20 pmMYR  Myrtle Beach Intl-PMO Palermo Punta Raisi
39h 00m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
2:20 pm - 10:37 amPMO  Palermo Punta Raisi-MYR Myrtle Beach Intl
26h 17m2 stops Newark Chicago O'Hare Intl
$941United Airlines
Sun, Dec 6 - Thu, Dec 10

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United Airlines flights from South Carolina to Palermo

Our best United Airlines deals on South Carolina to Palermo flight tickets
United Airlines
Dec 6
MYR3:20 pmMyrtle Beach Intl
39h 00m
2 stops
PMO12:20 pmPalermo Punta Raisi
Dec 10
PMO2:20 pmPalermo Punta Raisi
26h 17m
2 stops
MYR10:37 amMyrtle Beach Intl
$941
United Airlines
Dec 6
MYR11:25 amMyrtle Beach Intl
42h 55m
2 stops
PMO12:20 pmPalermo Punta Raisi
Dec 10
PMO2:20 pmPalermo Punta Raisi
32h 29m
1 stop
MYR4:49 pmMyrtle Beach Intl
$947
United Airlines
Oct 2
MYR5:00 pmMyrtle Beach Intl
56h 15m
2 stops
PMO7:15 amPalermo Punta Raisi
Oct 12
PMO9:45 amPalermo Punta Raisi
14h 27m
1 stop
MYR6:12 pmMyrtle Beach Intl
$1,041

Air Canada flights from South Carolina to Palermo

Our best Air Canada deals on South Carolina to Palermo flight tickets
Air Canada
Jan 8
MYR5:25 pmMyrtle Beach Intl
38h 55m
3 stops
PMO2:20 pmPalermo Punta Raisi
Jan 20
PMO10:05 amPalermo Punta Raisi
32h 35m
3 stops
MYR12:40 pmMyrtle Beach Intl
$1,156
Air Canada
Oct 28
MYR11:27 amMyrtle Beach Intl
19h 03m
3 stops
PMO11:30 amPalermo Punta Raisi
Nov 12
PMO6:10 amPalermo Punta Raisi
34h 11m
3 stops
MYR10:21 amMyrtle Beach Intl
$1,385
Air Canada
Oct 2
MYR10:38 amMyrtle Beach Intl
18h 52m
3 stops
PMO11:30 amPalermo Punta Raisi
Oct 12
PMO10:05 amPalermo Punta Raisi
29h 37m
3 stops
MYR9:42 amMyrtle Beach Intl
$1,920

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPalermo

MYR Myrtle Beach Intl - PMO Palermo Punta Raisi

MYRPMO

Myrtle Beach Intl

Wed 10/28

11:27 am-2:20 pm

2 stops21h 53m

Palermo Punta Raisi

Thu 11/12

6:10 am-6:06 pm

2 stops41h 56m

$792

Myrtle BeachPalermo

MYR Myrtle Beach Intl - PMO Palermo Punta Raisi

MYRPMO

Myrtle Beach Intl

Wed 10/28

11:27 am-12:20 pm

1 stop19h 53m

Palermo Punta Raisi

Thu 11/12

2:20 pm-10:21 am

1 stop26h 01m

$810

Myrtle BeachPalermo

MYR Myrtle Beach Intl - PMO Palermo Punta Raisi

MYRPMO

Myrtle Beach Intl

Wed 10/28

11:27 am-11:00 am

2 stops18h 33m

Palermo Punta Raisi

Thu 11/12

2:20 pm-10:21 am

1 stop26h 01m

$818

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Sat 1/9

6:50 pm-11:55 pm

2 stops23h 05m

Palermo Punta Raisi

Wed 1/20

6:15 am-4:55 pm

2 stops40h 40m

$839

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Wed 12/2

7:47 pm-11:25 am

2 stops33h 38m

Palermo Punta Raisi

Sun 12/6

2:45 pm-4:55 pm

2 stops56h 10m

$898

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Tue 9/22

6:40 pm-6:40 pm

2 stops18h 00m

Palermo Punta Raisi

Tue 9/29

9:45 am-9:15 pm

2 stops17h 30m

$917
Quickest round-trip

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Wed 11/4

2:28 pm-11:30 am

2 stops15h 02m

Palermo Punta Raisi

Wed 11/11

10:05 am-11:54 pm

2 stops19h 49m

$920

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Wed 12/2

7:47 pm-11:25 am

2 stops33h 38m

Palermo Punta Raisi

Sun 12/6

6:30 pm-4:55 pm

1 stop28h 25m

$927

CharlottePalermo

CLT Charlotte Douglas - PMO Palermo Punta Raisi

CLTPMO

Charlotte Douglas

Sun 9/6

6:40 pm-11:50 pm

2 stops23h 10m

Palermo Punta Raisi

Mon 9/14

11:40 pm-8:57 pm

3 stops27h 17m

$938

Myrtle BeachPalermo

MYR Myrtle Beach Intl - PMO Palermo Punta Raisi

MYRPMO

Myrtle Beach Intl

Sun 12/6

3:20 pm-12:20 pm

2 stops39h 00m

Palermo Punta Raisi

Thu 12/10

2:20 pm-10:37 am

2 stops26h 17m

$941

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Palermo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from South Carolina to Palermo Punta Raisi?

United Airlines and American Airlines are the most popular carriers operating from South Carolina to Palermo Punta Raisi

Cheap South Carolina to Palermo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Palermo

Fastest flight time

14h 37m

Direct flights

None
The fastest flight from South Carolina to Palermo takes 14h 37m
There are no direct flights from South Carolina to Palermo. There are no popular flight routes from South Carolina to Palermo.
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Frequently asked questions about flying from South Carolina to Palermo

  • When did momondo last update prices for flights from South Carolina to Palermo Punta Raisi Airport?

    Prices for flights from South Carolina to Palermo Punta Raisi Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Palermo Punta Raisi Airport?

  • How old do you have to be to fly from South Carolina to Palermo Punta Raisi Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Palermo Punta Raisi Airport.

  • What documentation or ID do you need to fly to Palermo Punta Raisi Airport?

    The necessary travel and health documents for your Palermo Punta Raisi Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Palermo

Compare and see reviews for airlines that fly from South Carolina to Palermo with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $745Free CancellationRating
6.8
8,177 reviews
Search Lufthansa flights

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Cefalù
San Vito Lo Capo
Agrigento
Scopello
Sciacca
Ustica
Castellammare del Golfo
Alcamo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Palermo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Palermo from South Carolina.

Can I find flights from South Carolina to Palermo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Palermo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Palermo?

Once all potential South Carolina to Palermo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

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Of course. momondo tracks the price of South Carolina to Palermo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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