Cheap flights from South Carolina to Palermo from $312

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Palermo departing on 4/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Palermo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:50 pm - 2:30 pm
CLT
-
PMO
37h 40m
2 stops
Multiple Airlines Logo
11:50 am - 11:57 pm
PMO
-
CLT
18h 07m
2 stops
$641Multiple Airlines
Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
7:50 pm - 2:30 pm
CLT
-
PMO
37h 40m
2 stops
Multiple Airlines Logo
11:50 am - 11:57 pm
PMO
-
CLT
18h 07m
2 stops
$643Multiple Airlines
Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
7:50 pm - 2:30 pm
CLT
-
PMO
37h 40m
2 stops
Multiple Airlines Logo
6:10 pm - 4:45 pm
PMO
-
CLT
28h 35m
1 stop
$645Multiple Airlines
Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
7:50 pm - 2:30 pm
CLT
-
PMO
37h 40m
2 stops
Multiple Airlines Logo
6:10 pm - 4:45 pm
PMO
-
CLT
28h 35m
1 stop
$646Multiple Airlines
Sun, Mar 22 - Tue, Mar 31
SWISS Logo
6:50 pm - 6:25 pm
CLT
-
PMO
17h 35m
2 stops
SWISS Logo
9:45 am - 4:55 pm
PMO
-
CLT
37h 10m
2 stops
$670SWISS
Sun, Feb 22 - Sat, Feb 28
British Airways Logo
6:18 pm - 11:10 am
CLT
-
PMO
34h 52m
2 stops
British Airways Logo
7:50 pm - 8:45 pm
PMO
-
CLT
30h 55m
1 stop
$694British Airways
Tue, Apr 14 - Mon, Apr 20
British Airways Logo
7:54 pm - 11:10 am
CLT
-
PMO
33h 16m
2 stops
British Airways Logo
7:50 pm - 9:52 pm
PMO
-
CLT
32h 02m
2 stops
$697British Airways
Tue, Apr 14 - Mon, Apr 20
Multiple Airlines Logo
6:50 pm - 2:30 pm
CLT
-
PMO
37h 40m
2 stops
Multiple Airlines Logo
12:10 pm - 4:55 pm
PMO
-
CLT
34h 45m
1 stop
$698Multiple Airlines
Sun, Feb 22 - Sat, Feb 28
United Airlines Logo
6:25 am - 11:40 am
CAE
-
PMO
23h 15m
2 stops
United Airlines Logo
6:10 am - 11:44 pm
PMO
-
CAE
23h 34m
2 stops
$1,253United Airlines
Thu, Feb 19 - Mon, Feb 23
Air Canada Logo
11:57 am - 2:25 pm
MYR
-
PMO
20h 28m
3 stops
Air Canada Logo
7:20 am - 11:14 am
PMO
-
MYR
33h 54m
3 stops
$2,158Air Canada
Thu, Apr 2 - Sat, Apr 11

Air Canada flights from South Carolina to Palermo

Our best Air Canada deals on South Carolina to Palermo flight tickets
Air Canada
Mar 4
CLT7:50 amCharlotte Douglas
21h 15m
2 stops
PMO11:05 amPalermo Punta Raisi
Mar 8
PMO10:05 amPalermo Punta Raisi
39h 52m
2 stops
CLT8:57 pmCharlotte Douglas
$878
Air Canada
Apr 14
CLT7:30 pmCharlotte Douglas
36h 55m
3 stops
PMO2:25 pmPalermo Punta Raisi
Apr 20
PMO7:20 amPalermo Punta Raisi
22h 37m
3 stops
CLT11:57 pmCharlotte Douglas
$1,181
Air Canada
Apr 2
MYR11:57 amMyrtle Beach Intl
20h 28m
3 stops
PMO2:25 pmPalermo Punta Raisi
Apr 11
PMO7:20 amPalermo Punta Raisi
33h 54m
3 stops
MYR11:14 amMyrtle Beach Intl
$2,158

SWISS flights from South Carolina to Palermo

Our best SWISS deals on South Carolina to Palermo flight tickets
SWISS
Feb 22
CLT6:50 pmCharlotte Douglas
17h 35m
2 stops
PMO6:25 pmPalermo Punta Raisi
Feb 28
PMO9:45 amPalermo Punta Raisi
37h 10m
2 stops
CLT4:55 pmCharlotte Douglas
$670
SWISS
Mar 5
CLT6:15 amCharlotte Douglas
30h 40m
2 stops
PMO6:55 pmPalermo Punta Raisi
Mar 15
PMO2:45 pmPalermo Punta Raisi
56h 10m
2 stops
CLT5:55 pmCharlotte Douglas
$770
SWISS
May 18
CLT6:40 pmCharlotte Douglas
32h 20m
2 stops
PMO9:00 amPalermo Punta Raisi
May 25
PMO9:45 amPalermo Punta Raisi
16h 34m
1 stop
CLT8:19 pmCharlotte Douglas
$925

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 3/22

7:50 pm-2:30 pm

2 stops37h 40m

Palermo Punta Raisi

Tue 3/31

11:50 am-11:57 pm

2 stops18h 07m

$641

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 3/22

7:50 pm-2:30 pm

2 stops37h 40m

Palermo Punta Raisi

Tue 3/31

11:50 am-11:57 pm

2 stops18h 07m

$643

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 3/22

7:50 pm-2:30 pm

2 stops37h 40m

Palermo Punta Raisi

Tue 3/31

6:10 pm-4:45 pm

1 stop28h 35m

$645

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 3/22

7:50 pm-2:30 pm

2 stops37h 40m

Palermo Punta Raisi

Tue 3/31

6:10 pm-4:45 pm

1 stop28h 35m

$646

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/22

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/28

9:45 am-4:55 pm

2 stops37h 10m

$670

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 4/14

6:18 pm-11:10 am

2 stops34h 52m

Palermo Punta Raisi

Mon 4/20

7:50 pm-8:45 pm

1 stop30h 55m

$694

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 4/14

7:54 pm-11:10 am

2 stops33h 16m

Palermo Punta Raisi

Mon 4/20

7:50 pm-9:52 pm

2 stops32h 02m

$697

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/22

6:50 pm-2:30 pm

2 stops37h 40m

Palermo Punta Raisi

Sat 2/28

12:10 pm-4:55 pm

1 stop34h 45m

$698

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Thu 2/19

6:25 am-11:40 am

2 stops23h 15m

Palermo Punta Raisi

Mon 2/23

6:10 am-11:44 pm

2 stops23h 34m

$1,253

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Thu 4/2

11:57 am-2:25 pm

3 stops20h 28m

Palermo Punta Raisi

Sat 4/11

7:20 am-11:14 am

3 stops33h 54m

$2,158

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Palermo from

How to get the cheapest flight ticket from South Carolina to Palermo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from South Carolina to Palermo Punta Raisi?

Lufthansa is the most popular carrier operating from South Carolina to Palermo Punta Raisi

Cheap South Carolina to Palermo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Palermo

Fastest flight time

14h 23m

Direct flights

None
The fastest flight from South Carolina to Palermo takes 14h 23m
There are no direct flights from South Carolina to Palermo. There are no popular flight routes from South Carolina to Palermo.
  • When did momondo last update prices for flights from South Carolina to Palermo Punta Raisi Airport?

    Prices for flights from South Carolina to Palermo Punta Raisi Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Palermo Punta Raisi Airport?

  • How old do you have to be to fly from South Carolina to Palermo Punta Raisi Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Palermo Punta Raisi Airport.

  • What documentation or ID do you need to fly to Palermo Punta Raisi Airport?

    The necessary travel and health documents for your Palermo Punta Raisi Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Palermo

Compare and see reviews for airlines that fly from South Carolina to Palermo with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $635Free CancellationRating
6.8
7,758 reviews
Search Lufthansa flights

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Cefalù
San Vito Lo Capo
Scopello
Sciacca
Castellammare del Golfo
Agrigento
Alcamo
Ustica

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Palermo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Palermo from South Carolina.

Can I find flights from South Carolina to Palermo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Palermo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Palermo?

Once all potential South Carolina to Palermo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

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Thu 3/5
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