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Cheap flights from South Carolina to Palermo from $492

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Palermo departing on 6/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Palermo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:16 am - 11:10 pm
CLT
-
PMO
30h 54m
2 stops
Multiple Airlines Logo
6:55 pm - 8:19 pm
PMO
-
CLT
31h 24m
3 stops
$768Multiple Airlines
Mon, May 4 - Mon, May 11
Lufthansa Logo
6:40 pm - 5:20 pm
CLT
-
PMO
16h 40m
1 stop
Lufthansa Logo
11:50 am - 11:57 pm
PMO
-
CLT
18h 07m
2 stops
$799Lufthansa
Tue, Apr 21 - Tue, Apr 28
Lufthansa Logo
7:30 pm - 5:20 pm
CLT
-
PMO
15h 50m
2 stops
Lufthansa Logo
11:50 am - 11:57 pm
PMO
-
CLT
18h 07m
2 stops
$803Lufthansa
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
12:50 pm - 11:10 pm
CLT
-
PMO
28h 20m
3 stops
Multiple Airlines Logo
6:55 pm - 8:19 pm
PMO
-
CLT
31h 24m
3 stops
$815Multiple Airlines
Mon, May 4 - Mon, May 11
Delta Logo
6:45 pm - 3:50 pm
MYR
-
PMO
39h 05m
2 stops
Delta Logo
4:45 pm - 11:39 pm
PMO
-
MYR
36h 54m
2 stops
$1,119Delta
Thu, Sep 10 - Sat, Sep 19
British Airways Logo
12:57 pm - 6:40 pm
MYR
-
PMO
23h 43m
2 stops
British Airways Logo
7:50 pm - 6:00 pm
PMO
-
MYR
28h 10m
2 stops
$1,184British Airways
Thu, Apr 16 - Mon, Apr 20
British Airways Logo
8:46 pm - 6:40 pm
MYR
-
PMO
39h 54m
2 stops
British Airways Logo
6:55 pm - 7:06 pm
PMO
-
MYR
30h 11m
2 stops
$1,581British Airways
Wed, Sep 9 - Sat, Sep 19
United Airlines Logo
2:29 pm - 11:30 am
CAE
-
PMO
39h 01m
2 stops
United Airlines Logo
7:20 am - 9:16 pm
PMO
-
CAE
19h 56m
2 stops
$1,626United Airlines
Sun, Aug 16 - Thu, Aug 20
Air Canada Logo
10:00 am - 1:40 pm
MYR
-
PMO
21h 40m
3 stops
Air Canada Logo
10:05 am - 8:58 am
PMO
-
MYR
28h 53m
3 stops
$2,004Air Canada
Thu, Sep 10 - Sat, Sep 19
United Airlines Logo
11:25 am - 11:30 am
MYR
-
PMO
18h 05m
2 stops
United Airlines Logo
9:45 am - 6:03 pm
PMO
-
MYR
14h 18m
1 stop
$2,032United Airlines
Wed, Sep 9 - Sat, Sep 19

SWISS flights from South Carolina to Palermo

Our best SWISS deals on South Carolina to Palermo flight tickets
SWISS
Sep 14
CLT8:05 amCharlotte Douglas
24h 00m
2 stops
PMO2:05 pmPalermo Punta Raisi
Sep 23
PMO7:25 pmPalermo Punta Raisi
27h 20m
2 stops
CLT4:45 pmCharlotte Douglas
$887
SWISS
Apr 10
CLT8:05 amCharlotte Douglas
18h 55m
2 stops
PMO9:00 amPalermo Punta Raisi
Apr 20
PMO9:45 amPalermo Punta Raisi
37h 00m
2 stops
CLT4:45 pmCharlotte Douglas
$894

American Airlines flights from South Carolina to Palermo

Our best American Airlines deals on South Carolina to Palermo flight tickets
American Airlines
May 8
CLT8:10 pmCharlotte Douglas
15h 45m
1 stop
PMO5:55 pmPalermo Punta Raisi
May 15
PMO7:50 pmPalermo Punta Raisi
23h 10m
1 stop
CLT1:00 pmCharlotte Douglas
$974
American Airlines
May 8
CLT6:00 pmCharlotte Douglas
17h 55m
2 stops
PMO5:55 pmPalermo Punta Raisi
May 15
PMO7:50 pmPalermo Punta Raisi
23h 10m
1 stop
CLT1:00 pmCharlotte Douglas
$979
American Airlines
May 8
CLT6:00 pmCharlotte Douglas
17h 55m
2 stops
PMO5:55 pmPalermo Punta Raisi
May 15
PMO7:50 pmPalermo Punta Raisi
26h 57m
2 stops
CLT4:47 pmCharlotte Douglas
$989

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Mon 5/4

10:16 am-11:10 pm

2 stops30h 54m

Palermo Punta Raisi

Mon 5/11

6:55 pm-8:19 pm

3 stops31h 24m

$768

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 4/21

6:40 pm-5:20 pm

1 stop16h 40m

Palermo Punta Raisi

Tue 4/28

11:50 am-11:57 pm

2 stops18h 07m

$799

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 4/21

7:30 pm-5:20 pm

2 stops15h 50m

Palermo Punta Raisi

Tue 4/28

11:50 am-11:57 pm

2 stops18h 07m

$803

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Mon 5/4

12:50 pm-11:10 pm

3 stops28h 20m

Palermo Punta Raisi

Mon 5/11

6:55 pm-8:19 pm

3 stops31h 24m

$815

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Thu 9/10

6:45 pm-3:50 pm

2 stops39h 05m

Palermo Punta Raisi

Sat 9/19

4:45 pm-11:39 pm

2 stops36h 54m

$1,119

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Thu 4/16

12:57 pm-6:40 pm

2 stops23h 43m

Palermo Punta Raisi

Mon 4/20

7:50 pm-6:00 pm

2 stops28h 10m

$1,184

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Wed 9/9

8:46 pm-6:40 pm

2 stops39h 54m

Palermo Punta Raisi

Sat 9/19

6:55 pm-7:06 pm

2 stops30h 11m

$1,581

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Sun 8/16

2:29 pm-11:30 am

2 stops39h 01m

Palermo Punta Raisi

Thu 8/20

7:20 am-9:16 pm

2 stops19h 56m

$1,626

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Thu 9/10

10:00 am-1:40 pm

3 stops21h 40m

Palermo Punta Raisi

Sat 9/19

10:05 am-8:58 am

3 stops28h 53m

$2,004
Quickest round-trip

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Wed 9/9

11:25 am-11:30 am

2 stops18h 05m

Palermo Punta Raisi

Sat 9/19

9:45 am-6:03 pm

1 stop14h 18m

$2,032

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Palermo from

How to get the cheapest flight ticket from South Carolina to Palermo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from South Carolina to Palermo Punta Raisi?

British Airways and Lufthansa are the most popular carriers operating from South Carolina to Palermo Punta Raisi

Cheap South Carolina to Palermo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Palermo

Fastest flight time

15h 05m

Direct flights

None
The fastest flight from South Carolina to Palermo takes 15h 05m
There are no direct flights from South Carolina to Palermo. There are no popular flight routes from South Carolina to Palermo.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Palermo Punta Raisi Airport?

    Prices for flights from South Carolina to Palermo Punta Raisi Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Palermo Punta Raisi Airport?

  • How old do you have to be to fly from South Carolina to Palermo Punta Raisi Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Palermo Punta Raisi Airport.

  • What documentation or ID do you need to fly to Palermo Punta Raisi Airport?

    The necessary travel and health documents for your Palermo Punta Raisi Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Palermo

Compare and see reviews for airlines that fly from South Carolina to Palermo with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $745Free CancellationRating
6.8
7,867 reviews
Search Lufthansa flights

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Cefalù
San Vito Lo Capo
Sciacca
Castellammare del Golfo
Agrigento
Alcamo
Scopello
Ustica

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Palermo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Palermo from South Carolina.

Can I find flights from South Carolina to Palermo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Palermo from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Palermo?

Once all potential South Carolina to Palermo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Palermo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Palermo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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