What is the cheapest airline that flies from South Carolina to Chicago O'Hare Intl?

Spirit Airlines, Frontier, and United Airlines are the most popular carriers operating from South Carolina to Chicago O'Hare Intl

What airlines fly to Chicago O'Hare Intl Airport?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from South Carolina according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 4 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Chicago O'Hare Intl Airport?

On average, it takes 2h 08m to fly from South Carolina to Chicago O'Hare Intl Airport if you fly out of Greenville (the most popular airport in South Carolina) and into Chicago O'Hare Intl Airport (the most popular airport in Chicago O'Hare Intl Airport). If you’re flying out of Columbia and into Chicago O'Hare Intl Airport, then the flight time is around 2h 16m.

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per day?

As of August 2025, 87 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 5:00PM, with 46% of daily flights taking off in the afternoon.

How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?

As of August 2025, there are 5 operators available to choose from for flights from South Carolina to Chicago O'Hare Intl Airport.

How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago O'Hare Intl Airport.

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$48 Cheap Flights from South Carolina to Chicago O'Hare Intl Airport in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from South Carolina to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

11:50 am - 1:12 pmCLT-ORD

2h 22mnonstop

7:40 am - 11:00 amORD-CLT

2h 20mnonstop

$85Frontier

Find Deal

jue., sep. 4 - lun., sep. 8

8:49 pm - 10:07 pmCLT-ORD

2h 18mnonstop

11:32 am - 2:37 pmORD-CLT

2h 05mnonstop

$86Frontier

Find Deal

lun., oct. 27 - jue., oct. 30

2:18 pm - 3:43 pmMYR-ORD

2h 25mnonstop

10:12 am - 1:13 pmORD-MYR

2h 01mnonstop

$99Spirit Airlines

Find Deal

jue., ago. 21 - dom., ago. 24

11:50 am - 1:12 pmCLT-ORD

2h 22mnonstop

4:35 pm - 11:36 pmORD-CLT

6h 01m1 stop

$125

Find Deal

jue., sep. 4 - sáb., sep. 6

2:18 pm - 3:43 pmMYR-ORD

2h 25mnonstop

11:36 am - 8:09 pmORD-MYR

7h 33m1 stop

$129Spirit Airlines

Find Deal

jue., ago. 21 - sáb., ago. 23

5:20 pm - 6:34 pmCLT-ORD

2h 14mnonstop

8:47 pm - 11:53 pmORD-CLT

2h 06mnonstop

$138American Airlines

Find Deal

vie., sep. 12 - vie., sep. 12

3:50 pm - 5:06 pmCLT-ORD

2h 16mnonstop

6:55 pm - 10:07 pmORD-CLT

2h 12mnonstop

$139American Airlines

Find Deal

mié., sep. 3 - sáb., sep. 6

4:48 pm - 11:59 pmCLT-ORD

8h 11m1 stop

7:40 am - 11:00 amORD-CLT

2h 20mnonstop

$140

Find Deal

mié., sep. 3 - jue., sep. 4

6:40 am - 8:00 amCLT-ORD

2h 20mnonstop

2:05 pm - 5:15 pmORD-CLT

2h 10mnonstop

$141United Airlines

Find Deal

jue., sep. 4 - sáb., sep. 6

5:30 pm - 6:55 pmCLT-ORD

2h 25mnonstop

7:22 am - 10:46 amORD-CLT

2h 24mnonstop

$151United Airlines

Find Deal

sáb., ago. 30 - sáb., sep. 6

Delta flights from South Carolina to Chicago O'Hare Intl Airport

Our best Delta deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

Delta

Aug 27

GSP7:05 amGreenville

4h 15m

1 stop

ORD10:20 amChicago O'Hare Intl

Sep 13

ORD11:15 amChicago O'Hare Intl

4h 01m

1 stop

GSP4:16 pmGreenville

$197

Find similar

Delta

Oct 1

CHS10:00 amCharleston

6h 51m

1 stop

ORD3:51 pmChicago O'Hare Intl

Oct 4

ORD9:50 amChicago O'Hare Intl

5h 36m

1 stop

CHS4:26 pmCharleston

$201

Find similar

Delta

Dec 12

MYR12:45 pmMyrtle Beach Intl

7h 32m

1 stop

ORD7:17 pmChicago O'Hare Intl

Dec 16

ORD7:00 amChicago O'Hare Intl

7h 31m

1 stop

MYR3:31 pmMyrtle Beach Intl

$211

Find similar

American Airlines flights from South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

American Airlines

Sep 12

CLT5:20 pmCharlotte Douglas

2h 14m

ORD6:34 pmChicago O'Hare Intl

Sep 12

ORD8:47 pmChicago O'Hare Intl

2h 06m

CLT11:53 pmCharlotte Douglas

$138

Find similar

American Airlines

Sep 17

SAV12:20 pmSavannah/Hilton Head

2h 35m

ORD1:55 pmChicago O'Hare Intl

Sep 20

ORD8:25 amChicago O'Hare Intl

2h 15m

SAV11:40 amSavannah/Hilton Head

$139

Find similar

American Airlines

Sep 12

CLT5:20 pmCharlotte Douglas

2h 14m

ORD6:34 pmChicago O'Hare Intl

Sep 14

ORD5:00 amChicago O'Hare Intl

2h 05m

CLT8:05 amCharlotte Douglas

$143

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

jue. 9/4

11:50 am-1:12 pm

Nonstop2h 22m

Chicago O'Hare Intl

lun. 9/8

7:40 am-11:00 am

Nonstop2h 20m

$85

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

lun. 10/27

8:49 pm-10:07 pm

Nonstop2h 18m

Chicago O'Hare Intl

jue. 10/30

11:32 am-2:37 pm

Nonstop2h 05m

$86

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

jue. 8/21

2:18 pm-3:43 pm

Nonstop2h 25m

Chicago O'Hare Intl

dom. 8/24

10:12 am-1:13 pm

Nonstop2h 01m

$99

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

jue. 9/4

11:50 am-1:12 pm

Nonstop2h 22m

Chicago O'Hare Intl

sáb. 9/6

4:35 pm-11:36 pm

1 stop6h 01m

$125

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

jue. 8/21

2:18 pm-3:43 pm

Nonstop2h 25m

Chicago O'Hare Intl

sáb. 8/23

11:36 am-8:09 pm

1 stop7h 33m

$129

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

vie. 9/12

5:20 pm-6:34 pm

Nonstop2h 14m

Chicago O'Hare Intl

vie. 9/12

8:47 pm-11:53 pm

Nonstop2h 06m

$138

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mié. 9/3

3:50 pm-5:06 pm

Nonstop2h 16m

Chicago O'Hare Intl

sáb. 9/6

6:55 pm-10:07 pm

Nonstop2h 12m

$139

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mié. 9/3

4:48 pm-11:59 pm

1 stop8h 11m

Chicago O'Hare Intl

jue. 9/4

7:40 am-11:00 am

Nonstop2h 20m

$140

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

jue. 9/4

6:40 am-8:00 am

Nonstop2h 20m

Chicago O'Hare Intl

sáb. 9/6

2:05 pm-5:15 pm

Nonstop2h 10m

$141

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

sáb. 8/30

5:30 pm-6:55 pm

Nonstop2h 25m

Chicago O'Hare Intl

sáb. 9/6

7:22 am-10:46 am

Nonstop2h 24m

$151

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from South Carolina averaging around $334.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $420. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $743.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $356 when looking at flights departing in the evening. Try not to purchase tickets in the afternoon because they tend to be around $548. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago O'Hare Intl flight route?

Fly from Myrtle Beach Intl to Chicago O'Hare Intl for the best South Carolina - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from South Carolina for as low as $285 on momondo.

What cabin class options are available on South Carolina to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Chicago O'Hare Intl Airport.

Cheap South Carolina to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago O'Hare Intl Airport

Best Price Found	$48
Fastest flight time	2h 04m
Direct flights	Every day

The best one-way flight to Chicago O'Hare Intl Airport from South Carolina in the past 72 hours is $48. The best round-trip flight deal from South Carolina to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $85.

The fastest flight from South Carolina to Chicago O'Hare Intl Airport takes 2h 04m

Direct flights go from South Carolina to Chicago O'Hare Intl Airport every day.

Search flight deals

When did momondo last update prices for flights from South Carolina to Chicago O'Hare Intl Airport?
Prices for flights from South Carolina to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?
As of August 2025, there are 5 operators available to choose from for flights from South Carolina to Chicago O'Hare Intl Airport.
How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Chicago O'Hare Intl Airport?
Based on momondo bookings for flights between South Carolina and Chicago O'Hare Intl Airport, the leading plane model is Embraer 175, making up 18.22% of the total bookings. Other popular models include Embraer 175 (Enhanced Winglets) with 15.91%, Embraer 170 with 14.60%, and Canadair (Bombardier) Regional Jet CRJ-550 with 8.26%.

Best airlines flying from South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago O'Hare Intl Airport with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $46	Free Cancellation	Rating 6.3 8,053 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $135	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $176	Free Cancellation	Rating 8.0 7,987 reviews	Search Delta flights
United Airlines	PriceFrom $193	Free Cancellation	Rating 7.4 8,912 reviews	Search United Airlines flights

Lake Geneva

Rockford

Schaumburg

South Haven

Merrillville

Gurnee

Naperville

Rosemont

Kenosha

New Buffalo

Joliet

Oak Brook

Racine

Hammond

Tinley Park

Elgin

Orland Park

Aurora

Janesville

Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Chicago?

Once you have performed a search for South Carolina to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

sáb. 8/9

sáb. 8/16

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chicago

Popular cities in the United States

Flights to New York John F Kennedy Intl Airportfrom $90

Flights to Dallas/Fort Worth Airportfrom $58

Flights to Newark Airportfrom $57

Flights to New York LaGuardia Airportfrom $58

Flights to Washington, D.C. Dulles Intl Airportfrom $71

Flights to Orlando Airportfrom $61

Flights to Washington, D.C. Reagan-National Airportfrom $111

Flights to Chicago Midway Airport

Flights to Dallas Love Field Airport

Cheap flights from South Carolina to Chicago from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 8/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from South Carolina to Chicago

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Delta flights from South Carolina to Chicago O'Hare Intl Airport

Our best Delta deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

American Airlines flights from South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Chicago O'Hare Intl Airport that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from South Carolina averaging around $334.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest South Carolina to Chicago O'Hare Intl flight route?

Fly from Myrtle Beach Intl to Chicago O'Hare Intl for the best South Carolina - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

What cabin class options are available on South Carolina to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Chicago O'Hare Intl Airport.

What is the cheapest airline that flies from South Carolina to Chicago O'Hare Intl?

Spirit Airlines, Frontier, and United Airlines are the most popular carriers operating from South Carolina to Chicago O'Hare Intl

What airlines fly to Chicago O'Hare Intl Airport?

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per day?

As of August 2025, 87 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 5:00PM, with 46% of daily flights taking off in the afternoon.

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per week?

As of August 2025, 615 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each week. The most common flight departure day for this route is Mon, with 19% of weekly flights taking off on this day.

How long does it take to fly to Chicago O'Hare Intl Airport?

Cheap South Carolina to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago O'Hare Intl Airport

Best Price Found

Fastest flight time

Direct flights

When did momondo last update prices for flights from South Carolina to Chicago O'Hare Intl Airport?

How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?

How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

What is the most popular plane model from South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago O'Hare Intl Airport with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Chicago?

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chicago

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo