Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Chicago from $91

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
10:01 am - 12:48 am
CLT
-
ORD
15h 47m
1 stop
Frontier Logo
4:59 pm - 11:34 am
ORD
-
CLT
17h 35m
1 stop
$190Frontier
Tue, Jun 9 - Tue, Jun 16
Frontier Logo
5:57 pm - 12:49 am
CLT
-
ORD
7h 52m
1 stop
Frontier Logo
12:29 am - 12:33 pm
ORD
-
CLT
11h 04m
1 stop
$195Frontier
Tue, Aug 11 - Tue, Aug 18
American Airlines Logo
12:22 pm - 1:54 pm
MYR
-
ORD
2h 32mnonstop
American Airlines Logo
8:30 am - 11:53 am
ORD
-
MYR
2h 23mnonstop
$217American Airlines
Wed, Jun 10 - Tue, Jun 16
Delta Logo
7:57 pm - 11:59 pm
MYR
-
ORD
5h 02m
1 stop
Delta Logo
8:08 am - 3:29 pm
ORD
-
MYR
6h 21m
1 stop
$237Delta
Wed, Jun 10 - Tue, Jun 16
United Airlines Logo
3:08 pm - 4:42 pm
MYR
-
ORD
2h 34mnonstop
United Airlines Logo
10:53 am - 2:12 pm
ORD
-
MYR
2h 19mnonstop
$244United Airlines
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
10:34 am - 2:29 pm
MYR
-
ORD
4h 55m
1 stop
United Airlines Logo
7:03 am - 10:36 am
ORD
-
MYR
2h 33mnonstop
$248United Airlines
Wed, Jun 10 - Tue, Jun 16
American Airlines Logo
6:06 pm - 9:33 pm
MYR
-
ORD
4h 27m
1 stop
American Airlines Logo
8:30 am - 11:53 am
ORD
-
MYR
2h 23mnonstop
$254American Airlines
Thu, Jun 4 - Tue, Jun 9
Multiple Airlines Logo
2:46 pm - 8:21 am
MYR
-
ORD
18h 35m
1 stop
Multiple Airlines Logo
4:49 pm - 8:50 am
ORD
-
MYR
15h 01m
1 stop
$259Multiple Airlines
Sun, Sep 13 - Wed, Sep 16
Delta Logo
7:57 pm - 11:59 pm
MYR
-
ORD
5h 02m
1 stop
Delta Logo
5:30 am - 10:44 am
ORD
-
MYR
4h 14m
1 stop
$264Delta
Wed, Jun 10 - Tue, Jun 16
Multiple Airlines Logo
10:07 am - 7:44 pm
GSP
-
ORD
10h 37m
2 stops
Multiple Airlines Logo
7:45 am - 6:30 pm
ORD
-
GSP
9h 45m
1 stop
$265Multiple Airlines
Thu, Sep 24 - Mon, Sep 28

American Airlines flights from South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on South Carolina to Chicago O'Hare Intl Airport flight tickets
American Airlines
Jun 10
MYR12:22 pmMyrtle Beach Intl
2h 32m
ORD1:54 pmChicago O'Hare Intl
Jun 16
ORD8:30 amChicago O'Hare Intl
2h 23m
MYR11:53 amMyrtle Beach Intl
$217
American Airlines
Jun 4
MYR6:06 pmMyrtle Beach Intl
4h 27m
1 stop
ORD9:33 pmChicago O'Hare Intl
Jun 9
ORD8:30 amChicago O'Hare Intl
2h 23m
MYR11:53 amMyrtle Beach Intl
$254
American Airlines
Jun 16
SAV1:22 pmSavannah/Hilton Head
2h 37m
ORD2:59 pmChicago O'Hare Intl
Jun 23
ORD9:30 amChicago O'Hare Intl
2h 12m
SAV12:42 pmSavannah/Hilton Head
$258

Delta flights from South Carolina to Chicago O'Hare Intl Airport

Our best Delta deals on South Carolina to Chicago O'Hare Intl Airport flight tickets
Delta
Jun 10
MYR7:57 pmMyrtle Beach Intl
5h 02m
1 stop
ORD11:59 pmChicago O'Hare Intl
Jun 16
ORD8:08 amChicago O'Hare Intl
6h 21m
1 stop
MYR3:29 pmMyrtle Beach Intl
$237
Delta
Jun 10
MYR7:57 pmMyrtle Beach Intl
5h 02m
1 stop
ORD11:59 pmChicago O'Hare Intl
Jun 16
ORD5:30 amChicago O'Hare Intl
4h 14m
1 stop
MYR10:44 amMyrtle Beach Intl
$264
Delta
Jun 17
MYR11:32 amMyrtle Beach Intl
5h 54m
1 stop
ORD4:26 pmChicago O'Hare Intl
Jun 24
ORD5:30 amChicago O'Hare Intl
4h 14m
1 stop
MYR10:44 amMyrtle Beach Intl
$268

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 6/9

10:01 am-12:48 am

1 stop15h 47m

Chicago O'Hare Intl

Tue 6/16

4:59 pm-11:34 am

1 stop17h 35m

$190

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 8/11

5:57 pm-12:49 am

1 stop7h 52m

Chicago O'Hare Intl

Tue 8/18

12:29 am-12:33 pm

1 stop11h 04m

$195

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 6/10

12:22 pm-1:54 pm

Nonstop2h 32m

Chicago O'Hare Intl

Tue 6/16

8:30 am-11:53 am

Nonstop2h 23m

$217

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 6/10

7:57 pm-11:59 pm

1 stop5h 02m

Chicago O'Hare Intl

Tue 6/16

8:08 am-3:29 pm

1 stop6h 21m

$237
Quickest round-trip

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 6/4

3:08 pm-4:42 pm

Nonstop2h 34m

Chicago O'Hare Intl

Tue 6/9

10:53 am-2:12 pm

Nonstop2h 19m

$244

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 6/10

10:34 am-2:29 pm

1 stop4h 55m

Chicago O'Hare Intl

Tue 6/16

7:03 am-10:36 am

Nonstop2h 33m

$248

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 6/4

6:06 pm-9:33 pm

1 stop4h 27m

Chicago O'Hare Intl

Tue 6/9

8:30 am-11:53 am

Nonstop2h 23m

$254

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sun 9/13

2:46 pm-8:21 am

1 stop18h 35m

Chicago O'Hare Intl

Wed 9/16

4:49 pm-8:50 am

1 stop15h 01m

$259

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 6/10

7:57 pm-11:59 pm

1 stop5h 02m

Chicago O'Hare Intl

Tue 6/16

5:30 am-10:44 am

1 stop4h 14m

$264

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 9/24

10:07 am-7:44 pm

2 stops10h 37m

Chicago O'Hare Intl

Mon 9/28

7:45 am-6:30 pm

1 stop9h 45m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of June is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from South Carolina averaging around $60.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $401. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $710.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $378 when looking at flights departing in the evening. Try not to purchase tickets at noon because they tend to be around $514. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago O'Hare Intl flight route?

Fly from Hilton Head Island to Chicago O'Hare Intl for the best South Carolina - Chicago O'Hare Intl flight prices

How far in advance should I book a flight from South Carolina to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $364 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from South Carolina for as low as $268 on momondo.

Can stopping save me money on South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 23% on your flight if you consider stops on a South Carolina to Chicago O'Hare Intl Airport flight.

Cheap South Carolina to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago O'Hare Intl Airport

Best Price Found

$180

Fastest flight time

2h 02m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from South Carolina in the past 72 hours is $180. The best round-trip flight deal from South Carolina to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $309.
The fastest flight from South Carolina to Chicago O'Hare Intl Airport takes 2h 02m
Direct flights go from South Carolina to Chicago O'Hare Intl Airport every day.
Search flight deals

Frequently asked questions about flying from South Carolina to Chicago O'Hare Intl Airport

  • When did momondo last update prices for flights from South Carolina to Chicago O'Hare Intl Airport?

    Prices for flights from South Carolina to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $60Free CancellationRating
6.2
8,626 reviews
Search Spirit Airlines flights
DeltaPriceFrom $107Free CancellationRating
7.9
8,452 reviews
Search Delta flights
American AirlinesPriceFrom $135Free CancellationRating
7.1
11,663 reviews
Search American Airlines flights
United AirlinesPriceFrom $178Free CancellationRating
7.4
9,715 reviews
Search United Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Rosemont
Naperville
Orland Park
New Buffalo
Oak Brook
Kenosha
Joliet
Aurora
Racine
Janesville
Hammond
Evanston
Elgin
Tinley Park

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Chicago?

Once you have performed a search for South Carolina to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 6/14
Sun 6/21
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chicago