What airlines fly to Chicago O'Hare Intl Airport?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from South Carolina according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 4 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Chicago O'Hare Intl Airport?

On average, it takes 2h 02m to fly from South Carolina to Chicago O'Hare Intl Airport if you fly out of Greenville (the most popular airport in South Carolina) and into Chicago O'Hare Intl Airport (the most popular airport in Chicago O'Hare Intl Airport). If you’re flying out of Columbia and into Chicago O'Hare Intl Airport, then the flight time is around 2h 16m.

What is the cheapest airline that flies from South Carolina to Chicago O'Hare Intl?

Spirit Airlines, United Airlines, and Frontier are the most popular carriers operating from South Carolina to Chicago O'Hare Intl

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per day?

As of February 2026, 69 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 5:00PM, with 55% of daily flights taking off in the afternoon.

How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?

As of February 2026, there are 5 operators available to choose from for flights from South Carolina to Chicago O'Hare Intl Airport.

How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago O'Hare Intl Airport.

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$53 Cheap Flights from South Carolina to Chicago O'Hare Intl Airport in 2026

Q: How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per week?

As of February 2026, 489 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each week. The most common flight departure day for this route is Mon, with 20% of weekly flights taking off on this day.

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Find the cheapest flights from South Carolina to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:42 pm - 12:13 am

CLT

ORD

2h 31mnonstop

7:11 pm - 10:13 pm

ORD

CLT

2h 02mnonstop

$62Frontier

Thu, Mar 19 - Mon, Mar 23

10:42 pm - 12:13 am

CLT

ORD

2h 31mnonstop

7:11 pm - 10:13 pm

ORD

CLT

2h 02mnonstop

$65Frontier

Fri, Mar 20 - Mon, Mar 23

10:42 pm - 12:13 am

CLT

ORD

2h 31mnonstop

7:11 pm - 10:13 pm

ORD

CLT

2h 02mnonstop

$66Frontier

Fri, Mar 20 - Mon, Mar 23

3:35 pm - 10:43 pm

CHS

ORD

8h 08m

1 stop

4:47 pm - 8:40 am

ORD

CHS

14h 53m

1 stop

$128Spirit Airlines

Wed, Apr 29 - Tue, May 5

3:35 pm - 10:43 pm

CHS

ORD

8h 08m

1 stop

4:47 pm - 8:40 am

ORD

CHS

14h 53m

1 stop

$129Spirit Airlines

Wed, Apr 29 - Tue, May 5

7:20 am - 1:20 pm

GSP

ORD

7h 00m

1 stop

5:30 am - 11:05 am

ORD

GSP

4h 35m

1 stop

$147Delta

Sat, Mar 7 - Wed, Mar 11

3:35 pm - 10:43 pm

CHS

ORD

8h 08m

1 stop

8:00 am - 9:29 pm

ORD

CHS

12h 29m

1 stop

$149Multiple Airlines

Tue, May 5 - Sat, May 9

3:35 pm - 10:43 pm

CHS

ORD

8h 08m

1 stop

1:27 pm - 10:41 pm

ORD

CHS

8h 14m

1 stop

$150Multiple Airlines

Wed, Apr 29 - Wed, May 6

4:22 pm - 10:56 pm

SAV

ORD

7h 34m

1 stop

7:45 am - 5:21 pm

ORD

SAV

8h 36m

1 stop

$172JetBlue

Wed, Mar 25 - Wed, Apr 1

7:59 pm - 11:59 pm

GSP

ORD

5h 00m

1 stop

5:10 am - 10:20 am

ORD

GSP

4h 10m

1 stop

$213Delta

Thu, Apr 23 - Sun, Apr 26

Frontier flights from South Carolina to Chicago O'Hare Intl Airport

Our best Frontier deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

Frontier

Mar 19

CLT10:42 pmCharlotte Douglas

2h 31m

ORD12:13 amChicago O'Hare Intl

Mar 23

ORD7:11 pmChicago O'Hare Intl

2h 02m

CLT10:13 pmCharlotte Douglas

$62

Frontier

Mar 20

CLT10:42 pmCharlotte Douglas

2h 31m

ORD12:13 amChicago O'Hare Intl

Mar 23

ORD7:11 pmChicago O'Hare Intl

2h 02m

CLT10:13 pmCharlotte Douglas

$65

Frontier

Mar 20

CLT10:42 pmCharlotte Douglas

2h 31m

ORD12:13 amChicago O'Hare Intl

Mar 23

ORD7:11 pmChicago O'Hare Intl

2h 02m

CLT10:13 pmCharlotte Douglas

$66

United Airlines flights from South Carolina to Chicago O'Hare Intl Airport

Our best United Airlines deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

United Airlines

Apr 15

CAE5:00 pmColumbia Metropolitan

2h 30m

ORD6:30 pmChicago O'Hare Intl

Apr 20

ORD7:00 amChicago O'Hare Intl

2h 06m

CAE10:06 amColumbia Metropolitan

$209

United Airlines

Mar 4

CAE6:25 amColumbia Metropolitan

2h 29m

ORD7:54 amChicago O'Hare Intl

Mar 7

ORD5:45 pmChicago O'Hare Intl

4h 59m

1 stop

CAE11:44 pmColumbia Metropolitan

$219

United Airlines

Mar 21

CAE6:15 amColumbia Metropolitan

2h 29m

ORD7:44 amChicago O'Hare Intl

Mar 29

ORD11:42 amChicago O'Hare Intl

2h 07m

CAE2:49 pmColumbia Metropolitan

$223

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 3/19

10:42 pm-12:13 am

Nonstop2h 31m

Chicago O'Hare Intl

Mon 3/23

7:11 pm-10:13 pm

Nonstop2h 02m

$62

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 3/20

10:42 pm-12:13 am

Nonstop2h 31m

Chicago O'Hare Intl

Mon 3/23

7:11 pm-10:13 pm

Nonstop2h 02m

$65

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 3/20

10:42 pm-12:13 am

Nonstop2h 31m

Chicago O'Hare Intl

Mon 3/23

7:11 pm-10:13 pm

Nonstop2h 02m

$66

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Wed 4/29

3:35 pm-10:43 pm

1 stop8h 08m

Chicago O'Hare Intl

Tue 5/5

4:47 pm-8:40 am

1 stop14h 53m

$128

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Wed 4/29

3:35 pm-10:43 pm

1 stop8h 08m

Chicago O'Hare Intl

Tue 5/5

4:47 pm-8:40 am

1 stop14h 53m

$129

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sat 3/7

7:20 am-1:20 pm

1 stop7h 00m

Chicago O'Hare Intl

Wed 3/11

5:30 am-11:05 am

1 stop4h 35m

$147

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Tue 5/5

3:35 pm-10:43 pm

1 stop8h 08m

Chicago O'Hare Intl

Sat 5/9

8:00 am-9:29 pm

1 stop12h 29m

$149

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Wed 4/29

3:35 pm-10:43 pm

1 stop8h 08m

Chicago O'Hare Intl

Wed 5/6

1:27 pm-10:41 pm

1 stop8h 14m

$150

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Wed 3/25

4:22 pm-10:56 pm

1 stop7h 34m

Chicago O'Hare Intl

Wed 4/1

7:45 am-5:21 pm

1 stop8h 36m

$172

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 4/23

7:59 pm-11:59 pm

1 stop5h 00m

Chicago O'Hare Intl

Sun 4/26

5:10 am-10:20 am

1 stop4h 10m

$213

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from South Carolina averaging around $301.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $407. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $703.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $356 when looking at flights departing in the evening. Try not to purchase tickets at noon because they tend to be around $595. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago O'Hare Intl flight route?

Fly from Charleston to Chicago O'Hare Intl for the best South Carolina - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $360 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from South Carolina for as low as $268 on momondo.

What cabin class options are available on South Carolina to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 17% on your flight if you consider stops on a South Carolina to Chicago O'Hare Intl Airport flight.

Cheap South Carolina to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago O'Hare Intl Airport

Best Price Found	$151
Fastest flight time	2h 02m
Direct flights	Every day

The best one-way flight to Chicago O'Hare Intl Airport from South Carolina in the past 72 hours is $151. The best round-trip flight deal from South Carolina to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $303.

The fastest flight from South Carolina to Chicago O'Hare Intl Airport takes 2h 02m

Direct flights go from South Carolina to Chicago O'Hare Intl Airport every day.

Search flight deals

When did momondo last update prices for flights from South Carolina to Chicago O'Hare Intl Airport?
Prices for flights from South Carolina to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?
As of February 2026, there are 5 operators available to choose from for flights from South Carolina to Chicago O'Hare Intl Airport.
How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Chicago O'Hare Intl Airport?
Based on momondo bookings for flights between South Carolina and Chicago O'Hare Intl Airport, the leading plane model is Embraer 175 (Enhanced Winglets), making up 24.20% of the total bookings. Other popular models include Embraer 175 with 15.44%, Canadair (Bombardier) Regional Jet CRJ-550 with 12.99%, and Embraer 170 with 10.49%.

Best airlines flying from South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago O'Hare Intl Airport with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $65	Free Cancellation	Rating 6.3 8,438 reviews	Search Spirit Airlines flights
Delta	PriceFrom $107	Free Cancellation	Rating 7.9 8,178 reviews	Search Delta flights
American Airlines	PriceFrom $135	Free Cancellation	Rating 7.2 11,259 reviews	Search American Airlines flights
United Airlines	PriceFrom $178	Free Cancellation	Rating 7.4 9,267 reviews	Search United Airlines flights

Lake Geneva

Schaumburg

South Haven

Rockford

Merrillville

Gurnee

Naperville

Rosemont

New Buffalo

Kenosha

Oak Brook

Joliet

Orland Park

Racine

Hammond

Janesville

Tinley Park

Elgin

Aurora

South Holland

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Chicago?

Once you have performed a search for South Carolina to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Chicago O'Hare Intl Airport trip

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Cheap flights from South Carolina to Chicago from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from South Carolina to Chicago O'Hare Intl Airport

Our best Frontier deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

United Airlines flights from South Carolina to Chicago O'Hare Intl Airport

Our best United Airlines deals on South Carolina to Chicago O'Hare Intl Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Chicago O'Hare Intl Airport that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago O'Hare Intl Airport

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from South Carolina averaging around $301.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest South Carolina to Chicago O'Hare Intl flight route?

Fly from Charleston to Chicago O'Hare Intl for the best South Carolina - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

What cabin class options are available on South Carolina to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 17% on your flight if you consider stops on a South Carolina to Chicago O'Hare Intl Airport flight.

What is the cheapest airline that flies from South Carolina to Chicago O'Hare Intl?

Spirit Airlines, United Airlines, and Frontier are the most popular carriers operating from South Carolina to Chicago O'Hare Intl

What airlines fly to Chicago O'Hare Intl Airport?

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per day?

As of February 2026, 69 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each day. The most common flight departure time for this route is 5:00PM, with 55% of daily flights taking off in the afternoon.

How many flights depart from South Carolina to Chicago O'Hare Intl Airport on average per week?

As of February 2026, 489 flights take off from South Carolina and land in Chicago O'Hare Intl Airport each week. The most common flight departure day for this route is Mon, with 20% of weekly flights taking off on this day.

How long does it take to fly to Chicago O'Hare Intl Airport?

Cheap South Carolina to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago O'Hare Intl Airport

Best Price Found

Fastest flight time

Direct flights

When did momondo last update prices for flights from South Carolina to Chicago O'Hare Intl Airport?

How many operators does momondo search for flights from South Carolina to Chicago O'Hare Intl Airport?

How old do you have to be to fly from South Carolina to Chicago O'Hare Intl Airport?

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

What is the most popular plane model from South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago O'Hare Intl Airport with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Chicago?

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chicago

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Popular flights according to clicks in the last 7 days on momondo

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Fly your favorite airline to Chicago

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List of cabin classes available on flights landing in Chicago. Availability may vary depending on flight origin and airline.

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