How many flights depart from South Carolina to Chicago Midway Airport on average per week?

38 flights are operational weekly from South Carolina to Chicago Midway Airport as of November 2025. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.

How long does it take to fly to Chicago Midway Airport?

On average, it takes 2h 02m to fly from South Carolina to Chicago Midway Airport if you fly out of Greenville (the most popular airport in South Carolina) and into Chicago O'Hare Intl Airport (the most popular airport in Chicago Midway Airport). If you’re flying out of Columbia and into Chicago O'Hare Intl Airport, then the flight time is around 2h 16m.

How many flights depart from South Carolina to Chicago Midway Airport on average per day?

The number of flights available between South Carolina and Chicago Midway Airport is 5 per day as of November 2025. The most frequent departure time is 6:00AM, with 44% of daily flights leaving at noon.

What is the cheapest airline that flies from South Carolina to Chicago Midway?

Frontier, Southwest, and Delta are the most popular carriers operating from South Carolina to Chicago Midway

When did momondo last update prices for flights from South Carolina to Chicago Midway Airport?

Prices for flights from South Carolina to Chicago Midway Airport are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Chicago Midway Airport?

The number of operators available for flights from South Carolina to Chicago Midway Airport is 4 as of November 2025.

How old do you have to be to fly from South Carolina to Chicago Midway Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Chicago Midway Airport.

What documentation or ID do you need to fly to Chicago Midway Airport?

The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$56 Cheap Flights from South Carolina to Chicago Midway Airport in 2025/26

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Cheap round-trip flights

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3:42 pm - 9:53 pmCLT-MDW

7h 11m1 stop

8:05 am - 8:16 pmMDW-CLT

11h 11m1 stop

$110Frontier

Find Deal

Thu, Dec 4 - Thu, Dec 11

3:42 pm - 9:53 pmCLT-MDW

7h 11m1 stop

8:05 am - 6:27 pmMDW-CLT

9h 22m1 stop

$124Frontier

Find Deal

Thu, Dec 4 - Fri, Dec 5

3:42 pm - 9:53 pmCLT-MDW

7h 11m1 stop

8:05 am - 5:47 pmMDW-CLT

8h 42m1 stop

$125Frontier

Find Deal

Thu, Dec 4 - Sun, Dec 7

3:42 pm - 9:53 pmCLT-MDW

7h 11m1 stop

2:01 pm - 9:43 pmMDW-CLT

6h 42m1 stop

$126Frontier

Find Deal

Thu, Dec 11 - Sun, Dec 14

7:45 pm - 8:45 pmCLT-MDW

2h 00mnonstop

1:30 pm - 4:20 pmMDW-CLT

1h 50mnonstop

$139Southwest

Find Deal

Mon, Nov 24 - Thu, Nov 27

7:45 pm - 8:45 pmCLT-MDW

2h 00mnonstop

5:35 am - 12:05 pmMDW-CLT

5h 30m1 stop

$149Southwest

Find Deal

Mon, Nov 24 - Thu, Nov 27

5:35 am - 1:01 pmCLT-MDW

8h 26m1 stop

7:44 am - 12:04 pmMDW-CLT

27h 20m1 stop

$153Multiple Airlines

Find Deal

Tue, Dec 2 - Tue, Dec 9

8:28 am - 11:42 amSAV-MDW

28h 14m1 stop

6:20 am - 9:05 amMDW-SAV

25h 45m1 stop

$173Multiple Airlines

Find Deal

Wed, Nov 19 - Sun, Nov 23

6:00 am - 8:49 amCLT-MDW

3h 49m1 stop

9:29 am - 4:13 pmMDW-CLT

5h 44m1 stop

$177Delta

Find Deal

Sat, Dec 6 - Sat, Dec 13

6:33 am - 11:55 amCLT-MDW

6h 22m1 stop

9:34 am - 4:13 pmMDW-CLT

5h 39m1 stop

$178Delta

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Wed, Dec 3 - Wed, Dec 10

Southwest flights from South Carolina to Chicago Midway Airport

Our best Southwest deals on South Carolina to Chicago Midway Airport flight tickets

Southwest

Nov 24

CLT7:45 pmCharlotte Douglas

2h 00m

MDW8:45 pmChicago Midway

Nov 27

MDW1:30 pmChicago Midway

1h 50m

CLT4:20 pmCharlotte Douglas

$139

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Southwest

Nov 24

CLT7:45 pmCharlotte Douglas

2h 00m

MDW8:45 pmChicago Midway

Nov 27

MDW5:35 amChicago Midway

5h 30m

1 stop

CLT12:05 pmCharlotte Douglas

$149

Find similar

Southwest

Dec 11

CLT6:20 pmCharlotte Douglas

2h 05m

MDW7:25 pmChicago Midway

Dec 16

MDW6:00 pmChicago Midway

1h 50m

CLT8:50 pmCharlotte Douglas

$151

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Frontier flights from South Carolina to Chicago Midway Airport

Our best Frontier deals on South Carolina to Chicago Midway Airport flight tickets

Frontier

Dec 4

CLT3:42 pmCharlotte Douglas

7h 11m

1 stop

MDW9:53 pmChicago Midway

Dec 11

MDW8:05 amChicago Midway

11h 11m

1 stop

CLT8:16 pmCharlotte Douglas

$110

Find similar

Frontier

Dec 4

CLT3:42 pmCharlotte Douglas

7h 11m

1 stop

MDW9:53 pmChicago Midway

Dec 5

MDW8:05 amChicago Midway

9h 22m

1 stop

CLT6:27 pmCharlotte Douglas

$124

Find similar

Frontier

Dec 4

CLT3:42 pmCharlotte Douglas

7h 11m

1 stop

MDW9:53 pmChicago Midway

Dec 7

MDW8:05 amChicago Midway

8h 42m

1 stop

CLT5:47 pmCharlotte Douglas

$125

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momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/4

3:42 pm-9:53 pm

1 stop7h 11m

Chicago Midway

Thu 12/11

8:05 am-8:16 pm

1 stop11h 11m

$110

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/4

3:42 pm-9:53 pm

1 stop7h 11m

Chicago Midway

Fri 12/5

8:05 am-6:27 pm

1 stop9h 22m

$124

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/4

3:42 pm-9:53 pm

1 stop7h 11m

Chicago Midway

Sun 12/7

8:05 am-5:47 pm

1 stop8h 42m

$125

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/11

3:42 pm-9:53 pm

1 stop7h 11m

Chicago Midway

Sun 12/14

2:01 pm-9:43 pm

1 stop6h 42m

$126

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Mon 11/24

7:45 pm-8:45 pm

Nonstop2h 00m

Chicago Midway

Thu 11/27

1:30 pm-4:20 pm

Nonstop1h 50m

$139

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Mon 11/24

7:45 pm-8:45 pm

Nonstop2h 00m

Chicago Midway

Thu 11/27

5:35 am-12:05 pm

1 stop5h 30m

$149

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 12/2

5:35 am-1:01 pm

1 stop8h 26m

Chicago Midway

Tue 12/9

7:44 am-12:04 pm

1 stop27h 20m

$153

SavannahChicago

SAV - MDW

SAVMDW

Savannah/Hilton Head

Wed 11/19

8:28 am-11:42 am

1 stop28h 14m

Chicago Midway

Sun 11/23

6:20 am-9:05 am

1 stop25h 45m

$173

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 12/6

6:00 am-8:49 am

1 stop3h 49m

Chicago Midway

Sat 12/13

9:29 am-4:13 pm

1 stop5h 44m

$177

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 12/3

6:33 am-11:55 am

1 stop6h 22m

Chicago Midway

Wed 12/10

9:34 am-4:13 pm

1 stop5h 39m

$178

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How to get the cheapest flight ticket from South Carolina to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Wednesday is the cheapest day to fly to Chicago Midway Airport from South Carolina. The lowest ticket price found for a Wednesday departure recently was $321. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Sunday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $522.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from South Carolina in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $304 when looking at flights departing in the afternoon. Try not to purchase tickets in the evening because they tend to be around $446. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago Midway flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago Midway flight prices

What cabin class options are available on South Carolina to Chicago Midway flights?

There is only 1 cabin class available to choose from on South Carolina to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago Midway Airport flights?

You could potentially save up to 64% on your flight if you consider stops on a South Carolina to Chicago Midway Airport flight.

Cheap South Carolina to Chicago Midway Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago Midway Airport

Best Price Found	$184
Fastest flight time	2h 00m
Direct flights	Every day

The best one-way flight to Chicago Midway Airport from South Carolina in the past 72 hours is $184. The best round-trip flight deal from South Carolina to Chicago Midway Airport found on momondo in the last 72 hours is $322.

The fastest flight from South Carolina to Chicago Midway Airport takes 2h 00m

Direct flights go from South Carolina to Chicago Midway Airport every day.

Search flight deals

When did momondo last update prices for flights from South Carolina to Chicago Midway Airport?
Prices for flights from South Carolina to Chicago Midway Airport are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Chicago Midway Airport?
The number of operators available for flights from South Carolina to Chicago Midway Airport is 4 as of November 2025.
How old do you have to be to fly from South Carolina to Chicago Midway Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Chicago Midway Airport.
What documentation or ID do you need to fly to Chicago Midway Airport?
The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from South Carolina to Chicago Midway Airport?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from South Carolina to Chicago Midway Airport is Airbus A319 (14.77% of total bookings). The next most popular plane models are Embraer 175 (Enhanced Winglets) (12.50%), Embraer 175 (11.93%), and Boeing 737 MAX 8 (10.23%).

Best airlines flying from South Carolina to Chicago Midway Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago Midway Airport with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $180	Free Cancellation	Rating 7.9 8,001 reviews		Search Delta flights
Southwest	PriceFrom $190	Free Cancellation	Rating 8.0 4,241 reviews		Search Southwest flights

Merrillville

New Buffalo

Hammond

Benton Harbor

Saint Joseph

Portage

Lansing

Schererville

Valparaiso

Crown Point

Munster

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Chicago.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Chicago Midway Airport trip

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Cheap flights from South Carolina to Chicago from $56

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from South Carolina to Chicago Midway Airport

Our best Southwest deals on South Carolina to Chicago Midway Airport flight tickets

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Our best Frontier deals on South Carolina to Chicago Midway Airport flight tickets

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Use the filters below to find and compare flights from South Carolina to Chicago Midway Airport that are best for you.

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How to get the cheapest flight ticket from South Carolina to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

What is the cheapest South Carolina to Chicago Midway flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago Midway flight prices

What cabin class options are available on South Carolina to Chicago Midway flights?

There is only 1 cabin class available to choose from on South Carolina to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago Midway Airport flights?

You could potentially save up to 64% on your flight if you consider stops on a South Carolina to Chicago Midway Airport flight.

What is the cheapest airline that flies from South Carolina to Chicago Midway?

Frontier, Southwest, and Delta are the most popular carriers operating from South Carolina to Chicago Midway

How many flights depart from South Carolina to Chicago Midway Airport on average per day?

The number of flights available between South Carolina and Chicago Midway Airport is 5 per day as of November 2025. The most frequent departure time is 6:00AM, with 44% of daily flights leaving at noon.

How many flights depart from South Carolina to Chicago Midway Airport on average per week?

38 flights are operational weekly from South Carolina to Chicago Midway Airport as of November 2025. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.

How long does it take to fly to Chicago Midway Airport?

Cheap South Carolina to Chicago Midway Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago Midway Airport

Best Price Found

Fastest flight time

Direct flights

When did momondo last update prices for flights from South Carolina to Chicago Midway Airport?

How many operators does momondo search for flights from South Carolina to Chicago Midway Airport?

How old do you have to be to fly from South Carolina to Chicago Midway Airport?

What documentation or ID do you need to fly to Chicago Midway Airport?

What is the most popular plane model from South Carolina to Chicago Midway Airport?

Best airlines flying from South Carolina to Chicago Midway Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago Midway Airport with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Chicago?

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago Midway Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chicago

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo