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Cheap flights from South Carolina to Chicago from $68

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
$139Southwest
Tue, Jan 13 - Tue, Jan 20
Multiple Airlines Logo
7:00 am - 2:06 pm
CLT
-
MDW
8h 06m1 stop
Multiple Airlines Logo
4:31 pm - 4:43 pm
MDW
-
CLT
23h 12m1 stop
$142Multiple Airlines
Fri, Jan 9 - Mon, Jan 12
Southwest Logo
1:05 pm - 5:20 pm
CLT
-
MDW
5h 15m1 stop
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
$149Southwest
Sat, Jan 17 - Sun, Jan 18
Frontier Logo
8:46 pm - 9:09 am
CLT
-
MDW
13h 23m1 stop
Frontier Logo
8:19 pm - 8:18 am
MDW
-
CLT
10h 59m1 stop
$153Frontier
Thu, Jan 15 - Sun, Jan 18
Frontier Logo
10:39 pm - 10:34 am
CLT
-
MDW
12h 55m2 stops
Frontier Logo
10:07 am - 10:40 am
MDW
-
CLT
23h 33m1 stop
$157Frontier
Mon, Jan 12 - Mon, Jan 19
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
$158Southwest
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
7:00 am - 2:06 pm
CLT
-
MDW
8h 06m1 stop
Multiple Airlines Logo
6:30 pm - 8:12 pm
MDW
-
CLT
24h 42m1 stop
$162Multiple Airlines
Fri, Jan 9 - Tue, Jan 13
Frontier Logo
8:46 pm - 11:09 pm
CLT
-
MDW
27h 23m1 stop
Frontier Logo
8:19 pm - 8:18 am
MDW
-
CLT
10h 59m1 stop
$163Frontier
Thu, Jan 8 - Thu, Jan 15
Delta Logo
7:20 am - 12:48 pm
GSP
-
MDW
6h 28m1 stop
Delta Logo
1:29 pm - 6:04 pm
MDW
-
GSP
3h 35m1 stop
$213Delta
Wed, Jan 14 - Wed, Jan 21
Delta Logo
7:20 am - 12:51 pm
GSP
-
MDW
6h 31m1 stop
Delta Logo
1:26 pm - 6:04 pm
MDW
-
GSP
3h 38m1 stop
$214Delta
Tue, Jan 20 - Sat, Jan 24

Southwest flights from South Carolina to Chicago Midway Airport

Our best Southwest deals on South Carolina to Chicago Midway Airport flight tickets
Southwest
Jan 17
CLT1:05 pmCharlotte Douglas
5h 15m
1 stop
MDW5:20 pmChicago Midway
Jan 18
MDW1:30 pmChicago Midway
1h 50m
CLT4:20 pmCharlotte Douglas
$149
Find similar
Southwest
Jan 15
CLT6:20 pmCharlotte Douglas
2h 05m
MDW7:25 pmChicago Midway
Jan 18
MDW1:30 pmChicago Midway
1h 50m
CLT4:20 pmCharlotte Douglas
$158
Find similar
Southwest
Jan 13
CLT5:50 pmCharlotte Douglas
2h 05m
MDW6:55 pmChicago Midway
Jan 16
MDW6:00 pmChicago Midway
1h 50m
CLT8:50 pmCharlotte Douglas
$168
Find similar

Frontier flights from South Carolina to Chicago Midway Airport

Our best Frontier deals on South Carolina to Chicago Midway Airport flight tickets
Frontier
Jan 15
CLT8:46 pmCharlotte Douglas
13h 23m
1 stop
MDW9:09 amChicago Midway
Jan 18
MDW8:19 pmChicago Midway
10h 59m
1 stop
CLT8:18 amCharlotte Douglas
$153
Find similar
Frontier
Jan 8
CLT8:46 pmCharlotte Douglas
27h 23m
1 stop
MDW11:09 pmChicago Midway
Jan 15
MDW8:19 pmChicago Midway
10h 59m
1 stop
CLT8:18 amCharlotte Douglas
$163
Find similar
Frontier
Jan 8
CLT1:30 pmCharlotte Douglas
25h 36m
1 stop
MDW2:06 pmChicago Midway
Jan 12
MDW9:15 amChicago Midway
6h 50m
1 stop
CLT5:05 pmCharlotte Douglas
$172
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 1/13

5:50 pm-6:55 pm

Nonstop2h 05m

Chicago Midway

Tue 1/20

1:30 pm-4:20 pm

Nonstop1h 50m

$139

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 1/9

7:00 am-2:06 pm

1 stop8h 06m

Chicago Midway

Mon 1/12

4:31 pm-4:43 pm

1 stop23h 12m

$142

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 1/17

1:05 pm-5:20 pm

1 stop5h 15m

Chicago Midway

Sun 1/18

1:30 pm-4:20 pm

Nonstop1h 50m

$149

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 1/15

8:46 pm-9:09 am

1 stop13h 23m

Chicago Midway

Sun 1/18

8:19 pm-8:18 am

1 stop10h 59m

$153

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Mon 1/12

10:39 pm-10:34 am

2 stops12h 55m

Chicago Midway

Mon 1/19

10:07 am-10:40 am

1 stop23h 33m

$157

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 1/15

6:20 pm-7:25 pm

Nonstop2h 05m

Chicago Midway

Sun 1/18

1:30 pm-4:20 pm

Nonstop1h 50m

$158

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 1/9

7:00 am-2:06 pm

1 stop8h 06m

Chicago Midway

Tue 1/13

6:30 pm-8:12 pm

1 stop24h 42m

$162

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 1/8

8:46 pm-11:09 pm

1 stop27h 23m

Chicago Midway

Thu 1/15

8:19 pm-8:18 am

1 stop10h 59m

$163

GreenvilleChicago

GSP - MDW

GSPMDW

Greenville

Wed 1/14

7:20 am-12:48 pm

1 stop6h 28m

Chicago Midway

Wed 1/21

1:29 pm-6:04 pm

1 stop3h 35m

$213

GreenvilleChicago

GSP - MDW

GSPMDW

Greenville

Tue 1/20

7:20 am-12:51 pm

1 stop6h 31m

Chicago Midway

Sat 1/24

1:26 pm-6:04 pm

1 stop3h 38m

$214

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Wednesday is the cheapest day to fly to Chicago Midway Airport from South Carolina. The lowest ticket price found for a Wednesday departure recently was $316. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Sunday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $496.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from South Carolina in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $304 when looking at flights departing in the afternoon. Try not to purchase tickets in the evening because they tend to be around $423. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago Midway flight route?

Fly from Charleston to Chicago Midway for the best South Carolina - Chicago Midway flight prices

What cabin class options are available on South Carolina to Chicago Midway flights?

There is only 1 cabin class available to choose from on South Carolina to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago Midway Airport flights?

You could potentially save up to 8% on your flight if you consider stops on a South Carolina to Chicago Midway Airport flight.

Cheap South Carolina to Chicago Midway Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago Midway Airport

Best Price Found

$182

Fastest flight time

1h 55m

Direct flights

Every day
The best one-way flight to Chicago Midway Airport from South Carolina in the past 72 hours is $182. The best round-trip flight deal from South Carolina to Chicago Midway Airport found on momondo in the last 72 hours is $376.
The fastest flight from South Carolina to Chicago Midway Airport takes 1h 55m
Direct flights go from South Carolina to Chicago Midway Airport every day.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Chicago Midway Airport?

    Prices for flights from South Carolina to Chicago Midway Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Chicago Midway Airport?

  • How old do you have to be to fly from South Carolina to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Chicago Midway Airport?

Best airlines flying from South Carolina to Chicago Midway Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $180Free CancellationRating
7.9
8,005 reviews
Search Delta flights
SouthwestPriceFrom $190Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Portage
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Valparaiso
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Crown Point
Munster
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Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Chicago.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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