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Cheap flights from South Carolina to Chicago from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:09 pm - 7:26 am
CLT
-
MDW
12h 17m
1 stop
Frontier Logo
6:15 am - 4:13 pm
MDW
-
CLT
8h 58m
1 stop
$160Frontier
Wed, Apr 22 - Fri, Apr 24
Southwest Logo
7:35 am - 8:45 am
CLT
-
MDW
2h 10mnonstop
Southwest Logo
6:00 pm - 8:55 pm
MDW
-
CLT
1h 55mnonstop
$167Southwest
Tue, Apr 21 - Tue, Apr 28
Delta Logo
6:24 pm - 10:28 pm
AGS
-
MDW
5h 04m
1 stop
Delta Logo
6:00 am - 11:09 am
MDW
-
AGS
4h 09m
1 stop
$167Delta
Sat, Apr 18 - Wed, Apr 22
Multiple Airlines Logo
8:43 pm - 1:00 pm
MYR
-
MDW
17h 17m
1 stop
Multiple Airlines Logo
7:30 am - 3:50 pm
MDW
-
MYR
7h 20m
1 stop
$167Multiple Airlines
Wed, Apr 22 - Sat, Apr 25
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
Southwest Logo
6:00 pm - 8:55 pm
MDW
-
CLT
1h 55mnonstop
$168Southwest
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
6:15 am - 2:01 pm
CLT
-
MDW
8h 46m
1 stop
Multiple Airlines Logo
7:30 am - 1:52 pm
MDW
-
CLT
5h 22m
1 stop
$171Multiple Airlines
Fri, Apr 10 - Tue, Apr 14
Multiple Airlines Logo
6:15 am - 2:01 pm
CLT
-
MDW
8h 46m
1 stop
Multiple Airlines Logo
7:30 am - 1:52 pm
MDW
-
CLT
5h 22m
1 stop
$172Multiple Airlines
Fri, Apr 10 - Tue, Apr 14
Multiple Airlines Logo
8:43 pm - 1:00 pm
MYR
-
MDW
17h 17m
1 stop
Multiple Airlines Logo
7:30 am - 8:13 am
MDW
-
MYR
23h 43m
1 stop
$175Multiple Airlines
Wed, Apr 22 - Fri, Apr 24
Frontier Logo
6:00 am - 8:47 am
CLT
-
MDW
3h 47m
1 stop
Frontier Logo
8:21 am - 5:45 pm
MDW
-
CLT
8h 24m
1 stop
$176Frontier
Thu, Apr 23 - Thu, Apr 30
Delta Logo
6:22 pm - 10:28 pm
AGS
-
MDW
5h 06m
1 stop
Delta Logo
10:41 am - 5:37 pm
MDW
-
AGS
5h 56m
1 stop
$239Delta
Thu, Apr 30 - Mon, May 4

Frontier flights from South Carolina to Chicago Midway Airport

Our best Frontier deals on South Carolina to Chicago Midway Airport flight tickets
Frontier
Apr 22
CLT8:09 pmCharlotte Douglas
12h 17m
1 stop
MDW7:26 amChicago Midway
Apr 24
MDW6:15 amChicago Midway
8h 58m
1 stop
CLT4:13 pmCharlotte Douglas
$160
Frontier
Apr 23
CLT6:00 amCharlotte Douglas
3h 47m
1 stop
MDW8:47 amChicago Midway
Apr 30
MDW8:21 amChicago Midway
8h 24m
1 stop
CLT5:45 pmCharlotte Douglas
$176
Frontier
Apr 24
CLT8:09 pmCharlotte Douglas
21h 04m
1 stop
MDW4:13 pmChicago Midway
Apr 26
MDW2:00 pmChicago Midway
18h 27m
1 stop
CLT9:27 amCharlotte Douglas
$180

Southwest flights from South Carolina to Chicago Midway Airport

Our best Southwest deals on South Carolina to Chicago Midway Airport flight tickets
Southwest
Apr 21
CLT7:35 amCharlotte Douglas
2h 10m
MDW8:45 amChicago Midway
Apr 28
MDW6:00 pmChicago Midway
1h 55m
CLT8:55 pmCharlotte Douglas
$167
Southwest
Apr 21
CLT6:20 pmCharlotte Douglas
2h 05m
MDW7:25 pmChicago Midway
Apr 28
MDW6:00 pmChicago Midway
1h 55m
CLT8:55 pmCharlotte Douglas
$168
Southwest
May 12
CLT7:35 amCharlotte Douglas
2h 10m
MDW8:45 amChicago Midway
May 13
MDW1:00 pmChicago Midway
6h 45m
1 stop
CLT8:45 pmCharlotte Douglas
$177

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from South Carolina to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 4/22

8:09 pm-7:26 am

1 stop12h 17m

Chicago Midway

Fri 4/24

6:15 am-4:13 pm

1 stop8h 58m

$160

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 4/21

7:35 am-8:45 am

Nonstop2h 10m

Chicago Midway

Tue 4/28

6:00 pm-8:55 pm

Nonstop1h 55m

$167

AugustaChicago

AGS - MDW

AGSMDW

Augusta Bush Field

Sat 4/18

6:24 pm-10:28 pm

1 stop5h 04m

Chicago Midway

Wed 4/22

6:00 am-11:09 am

1 stop4h 09m

$167

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 4/22

8:43 pm-1:00 pm

1 stop17h 17m

Chicago Midway

Sat 4/25

7:30 am-3:50 pm

1 stop7h 20m

$167
Quickest round-trip

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 4/21

6:20 pm-7:25 pm

Nonstop2h 05m

Chicago Midway

Tue 4/28

6:00 pm-8:55 pm

Nonstop1h 55m

$168

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 4/10

6:15 am-2:01 pm

1 stop8h 46m

Chicago Midway

Tue 4/14

7:30 am-1:52 pm

1 stop5h 22m

$171

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 4/10

6:15 am-2:01 pm

1 stop8h 46m

Chicago Midway

Tue 4/14

7:30 am-1:52 pm

1 stop5h 22m

$172

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 4/22

8:43 pm-1:00 pm

1 stop17h 17m

Chicago Midway

Fri 4/24

7:30 am-8:13 am

1 stop23h 43m

$175

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 4/23

6:00 am-8:47 am

1 stop3h 47m

Chicago Midway

Thu 4/30

8:21 am-5:45 pm

1 stop8h 24m

$176

AugustaChicago

AGS - MDW

AGSMDW

Augusta Bush Field

Thu 4/30

6:22 pm-10:28 pm

1 stop5h 06m

Chicago Midway

Mon 5/4

10:41 am-5:37 pm

1 stop5h 56m

$239

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago Midway Airport?

The month of October is, on average, the cheapest month to fly to Chicago Midway Airport from South Carolina, with most prices found around $229. If you are unable to visit Chicago Midway Airport during the month of October, then departing from South Carolina during the month July is also very affordable. Most momondo users find prices during this month for around $285.

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Thursday is the cheapest day to fly to Chicago Midway Airport from South Carolina. The lowest ticket price found for a Thursday departure recently was $352. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Sunday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $497.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from South Carolina in the morning is the least expensive time of day to depart. momondo users have found prices as low as $392 when looking at flights departing in the morning. Try not to purchase tickets in the evening because they tend to be around $446. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest South Carolina to Chicago Midway flight route?

Fly from Charleston to Chicago Midway for the best South Carolina - Chicago Midway flight prices

What cabin class options are available on South Carolina to Chicago Midway flights?

There is only 1 cabin class available to choose from on South Carolina to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Chicago Midway Airport.

Cheap South Carolina to Chicago Midway Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago Midway Airport

Best Price Found

$195

Fastest flight time

1h 55m

Direct flights

Every day
The best one-way flight to Chicago Midway Airport from South Carolina in the past 72 hours is $195. The best round-trip flight deal from South Carolina to Chicago Midway Airport found on momondo in the last 72 hours is $369.
The fastest flight from South Carolina to Chicago Midway Airport takes 1h 55m
Direct flights go from South Carolina to Chicago Midway Airport every day.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Chicago Midway Airport?

    Prices for flights from South Carolina to Chicago Midway Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Chicago Midway Airport?

  • How old do you have to be to fly from South Carolina to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The required travel and health documents for your Chicago Midway Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago Midway Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to Chicago Midway Airport?

Best airlines flying from South Carolina to Chicago Midway Airport

Compare and see reviews for airlines that fly from South Carolina to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $180Free CancellationRating
7.9
8,336 reviews
Search Delta flights
SouthwestPriceFrom $190Free CancellationRating
8.0
4,333 reviews
Search Southwest flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Hammond
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Benton Harbor
Portage
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Valparaiso
Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Chicago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Chicago.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Chicago Midway Airport trip

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