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Cheap flights from South Carolina to Mayagüez from $487

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Mayagüez departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:16 am - 9:42 am
CLT
-
MAZ
22h 26m1 stop
Multiple Airlines Logo
1:19 pm - 11:45 am
MAZ
-
CLT
23h 26m2 stops
$487Multiple Airlines
Mon, Jan 5 - Fri, Jan 9
Multiple Airlines Logo
9:00 am - 9:42 am
CLT
-
MAZ
23h 42m2 stops
Multiple Airlines Logo
4:36 pm - 12:40 am
MAZ
-
CLT
33h 04m3 stops
$735Multiple Airlines
Mon, Jan 5 - Fri, Jan 9
Multiple Airlines Logo
5:14 pm - 6:43 pm
CLT
-
MAZ
24h 29m3 stops
Multiple Airlines Logo
4:36 pm - 12:40 am
MAZ
-
CLT
33h 04m3 stops
$776Multiple Airlines
Mon, Jan 5 - Fri, Jan 9
United Airlines Logo
7:44 pm - 4:11 pm
CLT
-
MAZ
19h 27m2 stops
United Airlines Logo
1:19 pm - 10:33 am
MAZ
-
CLT
22h 14m2 stops
$1,567United Airlines
Mon, Jan 26 - Thu, Jan 29
United Airlines Logo
7:44 pm - 4:11 pm
CLT
-
MAZ
19h 27m2 stops
United Airlines Logo
1:19 pm - 10:33 am
MAZ
-
CLT
22h 14m2 stops
$1,977United Airlines
Sun, Jan 25 - Thu, Jan 29

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from South Carolina to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 1/5

10:16 am-9:42 am

1 stop22h 26m

Mayagüez Eugenio M De Hostos

Fri 1/9

1:19 pm-11:45 am

2 stops23h 26m

$487

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 1/5

9:00 am-9:42 am

2 stops23h 42m

Mayagüez Eugenio M De Hostos

Fri 1/9

4:36 pm-12:40 am

3 stops33h 04m

$735

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 1/5

5:14 pm-6:43 pm

3 stops24h 29m

Mayagüez Eugenio M De Hostos

Fri 1/9

4:36 pm-12:40 am

3 stops33h 04m

$776

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 1/26

7:44 pm-4:11 pm

2 stops19h 27m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-10:33 am

2 stops22h 14m

$1,567

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Sun 1/25

7:44 pm-4:11 pm

2 stops19h 27m

Mayagüez Eugenio M De Hostos

Thu 1/29

1:19 pm-10:33 am

2 stops22h 14m

$1,977

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Mayagüez from

How to get the cheapest flight ticket from South Carolina to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from South Carolina according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

Cheap South Carolina to Mayagüez flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Mayagüez

Fastest flight time

19h 27m

Direct flights

None
The fastest flight from South Carolina to Mayagüez takes 19h 27m
There are no direct flights from South Carolina to Mayagüez. There are no popular flight routes from South Carolina to Mayagüez.
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  • When did momondo last update prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport were last updated today.

  • How old do you have to be to fly from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Mayagüez?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Mayagüez. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Mayagüez with flexible booking policies on momondo?

All flight searches from South Carolina to Mayagüez on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from South Carolina.

I’m not ready to book a flight from South Carolina to Mayagüez right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Mayagüez flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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