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Cheap flights from South Carolina to Mayagüez from $385

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Mayagüez departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from South Carolina to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:31 pm - 9:42 am
CLT
-
MAZ
35h 11m
2 stops
Multiple Airlines Logo
1:19 pm - 7:32 pm
MAZ
-
CLT
6h 13m
1 stop
$385Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
10h 11m
2 stops
Multiple Airlines Logo
4:36 pm - 9:10 am
MAZ
-
CLT
16h 34m
2 stops
$418Multiple Airlines
Fri, Apr 10 - Tue, Apr 14
Multiple Airlines Logo
8:17 pm - 4:11 pm
CLT
-
MAZ
19h 54m
1 stop
Multiple Airlines Logo
1:19 pm - 7:32 pm
MAZ
-
CLT
6h 13m
1 stop
$457Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
Multiple Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
34h 11m
3 stops
Multiple Airlines Logo
7:35 am - 9:10 am
MAZ
-
CLT
25h 35m
2 stops
$464Multiple Airlines
Fri, Apr 10 - Tue, Apr 14
Multiple Airlines Logo
4:48 pm - 9:42 am
CLT
-
MAZ
16h 54m
2 stops
Multiple Airlines Logo
4:36 pm - 7:32 pm
MAZ
-
CLT
26h 56m
1 stop
$494Multiple Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
34h 11m
3 stops
Multiple Airlines Logo
4:36 pm - 8:49 pm
MAZ
-
CLT
28h 13m
3 stops
$532Multiple Airlines
Fri, Apr 10 - Tue, Apr 14
United Airlines Logo
7:00 am - 4:11 pm
CLT
-
MAZ
9h 11m
2 stops
United Airlines Logo
1:19 pm - 12:45 am
MAZ
-
CLT
11h 26m
2 stops
$1,558United Airlines
Thu, Apr 23 - Thu, Apr 30
United Airlines Logo
7:40 pm - 4:11 pm
CLT
-
MAZ
20h 31m
2 stops
United Airlines Logo
1:19 pm - 12:45 am
MAZ
-
CLT
11h 26m
2 stops
$1,708United Airlines
Sun, Apr 26 - Thu, Apr 30
United Airlines Logo
7:00 am - 4:11 pm
CLT
-
MAZ
9h 11m
2 stops
United Airlines Logo
1:19 pm - 11:59 pm
MAZ
-
CLT
10h 40m
2 stops
$1,727United Airlines
Sat, Apr 25 - Sat, May 2
United Airlines Logo
11:00 am - 4:11 pm
MYR
-
MAZ
29h 11m
2 stops
United Airlines Logo
1:19 pm - 10:18 am
MAZ
-
MYR
20h 59m
2 stops
$1,858United Airlines
Thu, Apr 9 - Mon, Apr 13

United Airlines flights from South Carolina to Mayagüez

Our best United Airlines deals on South Carolina to Mayagüez flight tickets
United Airlines
Apr 23
CLT7:00 amCharlotte Douglas
9h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Apr 30
MAZ1:19 pmMayagüez Eugenio M De Hostos
11h 26m
2 stops
CLT12:45 amCharlotte Douglas
$1,558
United Airlines
Apr 26
CLT7:40 pmCharlotte Douglas
20h 31m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Apr 30
MAZ1:19 pmMayagüez Eugenio M De Hostos
11h 26m
2 stops
CLT12:45 amCharlotte Douglas
$1,708
United Airlines
Apr 25
CLT7:00 amCharlotte Douglas
9h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
May 2
MAZ1:19 pmMayagüez Eugenio M De Hostos
10h 40m
2 stops
CLT11:59 pmCharlotte Douglas
$1,727

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from South Carolina to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Thu 4/23

10:31 pm-9:42 am

2 stops35h 11m

Mayagüez Eugenio M De Hostos

Thu 4/30

1:19 pm-7:32 pm

1 stop6h 13m

$385

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Fri 4/10

6:00 am-4:11 pm

2 stops10h 11m

Mayagüez Eugenio M De Hostos

Tue 4/14

4:36 pm-9:10 am

2 stops16h 34m

$418

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Thu 4/23

8:17 pm-4:11 pm

1 stop19h 54m

Mayagüez Eugenio M De Hostos

Thu 4/30

1:19 pm-7:32 pm

1 stop6h 13m

$457

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Fri 4/10

6:00 am-4:11 pm

3 stops34h 11m

Mayagüez Eugenio M De Hostos

Tue 4/14

7:35 am-9:10 am

2 stops25h 35m

$464

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Sat 4/25

4:48 pm-9:42 am

2 stops16h 54m

Mayagüez Eugenio M De Hostos

Sat 5/2

4:36 pm-7:32 pm

1 stop26h 56m

$494

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Fri 4/10

6:00 am-4:11 pm

3 stops34h 11m

Mayagüez Eugenio M De Hostos

Tue 4/14

4:36 pm-8:49 pm

3 stops28h 13m

$532

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Thu 4/23

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Thu 4/30

1:19 pm-12:45 am

2 stops11h 26m

$1,558

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Sun 4/26

7:40 pm-4:11 pm

2 stops20h 31m

Mayagüez Eugenio M De Hostos

Thu 4/30

1:19 pm-12:45 am

2 stops11h 26m

$1,708
Quickest round-trip

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Sat 4/25

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Sat 5/2

1:19 pm-11:59 pm

2 stops10h 40m

$1,727

Myrtle BeachMayagüez

MYR - MAZ

MYRMAZ

Myrtle Beach Intl

Thu 4/9

11:00 am-4:11 pm

2 stops29h 11m

Mayagüez Eugenio M De Hostos

Mon 4/13

1:19 pm-10:18 am

2 stops20h 59m

$1,858

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from South Carolina to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from South Carolina to Mayagüez Eugenio M De Hostos?

United Airlines is the most popular carrier operating from South Carolina to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from South Carolina according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 7 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

Cheap South Carolina to Mayagüez flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Mayagüez

Fastest flight time

20h 31m

Direct flights

None
The fastest flight from South Carolina to Mayagüez takes 20h 31m
There are no direct flights from South Carolina to Mayagüez. There are no popular flight routes from South Carolina to Mayagüez.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport were last updated today.

  • How old do you have to be to fly from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Mayagüez?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Mayagüez. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Mayagüez with flexible booking policies on momondo?

All flight searches from South Carolina to Mayagüez on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from South Carolina.

I’m not ready to book a flight from South Carolina to Mayagüez right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Mayagüez flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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