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Cheap flights from South Carolina to Mayagüez from $544

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Mayagüez departing on 7/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from South Carolina to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:28 pm - 12:44 pm
CLT
-
MAZ
16h 16m
1 stop
Multiple Airlines Logo
1:19 pm - 11:29 am
MAZ
-
CLT
22h 10m
2 stops
$544Multiple Airlines
Mon, Jul 13 - Fri, Jul 17
Multiple Airlines Logo
8:28 pm - 12:44 pm
CLT
-
MAZ
16h 16m
1 stop
Multiple Airlines Logo
1:19 pm - 7:33 pm
MAZ
-
CLT
6h 14m
1 stop
$545Multiple Airlines
Mon, Jul 13 - Fri, Jul 17
Multiple Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
10h 11m
2 stops
Multiple Airlines Logo
7:35 am - 9:15 pm
MAZ
-
CLT
13h 40m
2 stops
$769Multiple Airlines
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
10h 11m
2 stops
United Airlines Logo
1:19 pm - 11:56 pm
MAZ
-
CLT
10h 37m
2 stops
$1,021United Airlines
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
10h 11m
2 stops
United Airlines Logo
1:19 pm - 11:59 pm
MAZ
-
CLT
10h 40m
2 stops
$1,558United Airlines
Thu, Jul 16 - Mon, Jul 20
United Airlines Logo
6:00 am - 4:11 pm
CLT
-
MAZ
10h 11m
2 stops
United Airlines Logo
1:19 pm - 11:59 pm
MAZ
-
CLT
10h 40m
2 stops
$1,591United Airlines
Mon, Jul 13 - Fri, Jul 17
United Airlines Logo
10:34 am - 4:11 pm
MYR
-
MAZ
29h 37m
2 stops
United Airlines Logo
1:19 pm - 9:59 am
MAZ
-
MYR
20h 40m
2 stops
$1,595United Airlines
Fri, Jul 10 - Tue, Jul 14
United Airlines Logo
3:55 pm - 4:11 pm
CLT
-
MAZ
24h 16m
2 stops
United Airlines Logo
1:19 pm - 11:59 pm
MAZ
-
CLT
10h 40m
2 stops
$1,708United Airlines
Wed, Jul 15 - Mon, Jul 20
United Airlines Logo
10:23 am - 4:11 pm
MYR
-
MAZ
29h 48m
2 stops
United Airlines Logo
1:19 pm - 9:44 am
MAZ
-
MYR
20h 25m
2 stops
$1,724United Airlines
Thu, Aug 27 - Sun, Aug 30
United Airlines Logo
6:30 am - 3:49 pm
CAE
-
MAZ
32h 19m
2 stops
United Airlines Logo
1:25 pm - 4:45 pm
MAZ
-
CAE
28h 20m
2 stops
$1,858United Airlines
Mon, Dec 7 - Fri, Dec 11

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United Airlines flights from South Carolina to Mayagüez

Our best United Airlines deals on South Carolina to Mayagüez flight tickets
United Airlines
Sep 25
CLT6:00 amCharlotte Douglas
10h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Sep 28
MAZ1:19 pmMayagüez Eugenio M De Hostos
10h 37m
2 stops
CLT11:56 pmCharlotte Douglas
$1,021
United Airlines
Jul 16
CLT6:00 amCharlotte Douglas
10h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Jul 20
MAZ1:19 pmMayagüez Eugenio M De Hostos
10h 40m
2 stops
CLT11:59 pmCharlotte Douglas
$1,558
United Airlines
Jul 13
CLT6:00 amCharlotte Douglas
10h 11m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Jul 17
MAZ1:19 pmMayagüez Eugenio M De Hostos
10h 40m
2 stops
CLT11:59 pmCharlotte Douglas
$1,591

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 30, 2026.
Use the filters below to find and compare flights from South Carolina to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 7/13

8:28 pm-12:44 pm

1 stop16h 16m

Mayagüez Eugenio M De Hostos

Fri 7/17

1:19 pm-11:29 am

2 stops22h 10m

$544

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 7/13

8:28 pm-12:44 pm

1 stop16h 16m

Mayagüez Eugenio M De Hostos

Fri 7/17

1:19 pm-7:33 pm

1 stop6h 14m

$545

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Fri 9/25

6:00 am-4:11 pm

2 stops10h 11m

Mayagüez Eugenio M De Hostos

Mon 9/28

7:35 am-9:15 pm

2 stops13h 40m

$769
Quickest round-trip

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Fri 9/25

6:00 am-4:11 pm

2 stops10h 11m

Mayagüez Eugenio M De Hostos

Mon 9/28

1:19 pm-11:56 pm

2 stops10h 37m

$1,021

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Thu 7/16

6:00 am-4:11 pm

2 stops10h 11m

Mayagüez Eugenio M De Hostos

Mon 7/20

1:19 pm-11:59 pm

2 stops10h 40m

$1,558

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Mon 7/13

6:00 am-4:11 pm

2 stops10h 11m

Mayagüez Eugenio M De Hostos

Fri 7/17

1:19 pm-11:59 pm

2 stops10h 40m

$1,591

Myrtle BeachMayagüez

MYR - MAZ

MYRMAZ

Myrtle Beach Intl

Fri 7/10

10:34 am-4:11 pm

2 stops29h 37m

Mayagüez Eugenio M De Hostos

Tue 7/14

1:19 pm-9:59 am

2 stops20h 40m

$1,595

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Wed 7/15

3:55 pm-4:11 pm

2 stops24h 16m

Mayagüez Eugenio M De Hostos

Mon 7/20

1:19 pm-11:59 pm

2 stops10h 40m

$1,708

Myrtle BeachMayagüez

MYR - MAZ

MYRMAZ

Myrtle Beach Intl

Thu 8/27

10:23 am-4:11 pm

2 stops29h 48m

Mayagüez Eugenio M De Hostos

Sun 8/30

1:19 pm-9:44 am

2 stops20h 25m

$1,724

ColumbiaMayagüez

CAE - MAZ

CAEMAZ

Columbia Metropolitan

Mon 12/7

6:30 am-3:49 pm

2 stops32h 19m

Mayagüez Eugenio M De Hostos

Fri 12/11

1:25 pm-4:45 pm

2 stops28h 20m

$1,858

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Mayagüez from

How to get the cheapest flight ticket from South Carolina to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Mayagüez?

American Airlines, Delta and JetBlue are the top three most popular airlines that fly to Mayagüez from South Carolina according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 5 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

Cheap South Carolina to Mayagüez flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Mayagüez

Fastest flight time

10h 11m

Direct flights

None
The fastest flight from South Carolina to Mayagüez takes 10h 11m
There are no direct flights from South Carolina to Mayagüez. There are no popular flight routes from South Carolina to Mayagüez.
Search flight deals

Frequently asked questions about flying from South Carolina to Mayagüez

  • When did momondo last update prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from South Carolina to Mayagüez Eugenio M De Hostos Airport were last updated today.

  • How old do you have to be to fly from South Carolina to Mayagüez Eugenio M De Hostos Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The required travel and health documents for your Mayagüez Eugenio M De Hostos Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Mayagüez?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Mayagüez. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Mayagüez with flexible booking policies on momondo?

All flight searches from South Carolina to Mayagüez on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Mayagüez?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mayagüez from South Carolina.

I’m not ready to book a flight from South Carolina to Mayagüez right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Mayagüez flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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