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Cheap flights from South Carolina to Manchester from $368

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 12/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Manchester

Cheap round-trip flights

Enter your travel dates to find the best prices.
Aer Lingus Logo
1:45 pm - 7:35 amCLT  Charlotte Douglas-MAN Manchester
12h 50m2 stops Toronto Pearson Intl Dublin
Aer Lingus Logo
10:00 am - 8:45 pmMAN  Manchester-CLT Charlotte Douglas
15h 45m2 stops Dublin Toronto Pearson Intl
$581Aer Lingus
Wed, Jan 27 - Mon, Feb 1
United Airlines Logo
11:25 am - 5:00 pmMYR  Myrtle Beach Intl-MAN Manchester
24h 35m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 am - 2:33 pmMAN  Manchester-MYR Myrtle Beach Intl
32h 03m2 stops Toronto Pearson Intl Chicago O'Hare Intl
$792United Airlines
Tue, Dec 8 - Thu, Dec 10
British Airways Logo
10:30 pm - 4:20 pmCLT  Charlotte Douglas-MAN Manchester
12h 50m1 stop London Heathrow
British Airways Logo
6:50 pm - 2:20 pmMAN  Manchester-CLT Charlotte Douglas
24h 30m1 stop London Heathrow
$868British Airways
Wed, Jan 27 - Mon, Feb 1
British Airways Logo
4:15 pm - 11:20 amCLT  Charlotte Douglas-MAN Manchester
15h 05m2 stops Baltimore/Washington London Heathrow
British Airways Logo
7:45 am - 5:04 pmMAN  Manchester-CLT Charlotte Douglas
14h 19m2 stops London Heathrow New York John F Kennedy Intl
$906British Airways
Tue, Oct 27 - Fri, Nov 6
Delta Logo
12:26 pm - 8:45 amSAV  Savannah/Hilton Head-MAN Manchester
15h 19m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:40 pm - 11:59 pmMAN  Manchester-SAV Savannah/Hilton Head
16h 19m1 stop Atlanta Hartsfield-Jackson
$917Delta
Wed, Feb 3 - Wed, Feb 10
Delta Logo
11:45 am - 10:05 amSAV  Savannah/Hilton Head-MAN Manchester
17h 20m2 stops New York John F Kennedy Intl Paris Charles de Gaulle
Delta Logo
12:40 pm - 8:47 pmMAN  Manchester-SAV Savannah/Hilton Head
13h 07m1 stop Atlanta Hartsfield-Jackson
$922Delta
Wed, Feb 3 - Wed, Feb 10
Virgin Atlantic Logo
2:50 pm - 10:30 amSAV  Savannah/Hilton Head-MAN Manchester
14h 40m1 stop Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
12:40 pm - 9:15 pmMAN  Manchester-SAV Savannah/Hilton Head
13h 35m1 stop Atlanta Hartsfield-Jackson
$926Virgin Atlantic
Tue, Nov 24 - Wed, Dec 2
American Airlines Logo
11:10 pm - 7:05 pmCLT  Charlotte Douglas-MAN Manchester
14h 55m1 stop London Heathrow
American Airlines Logo
7:05 am - 6:55 pmMAN  Manchester-CLT Charlotte Douglas
16h 50m1 stop London Heathrow
$930American Airlines
Wed, Sep 16 - Wed, Sep 30
American Airlines Logo
11:10 pm - 7:05 pmCLT  Charlotte Douglas-MAN Manchester
14h 55m1 stop London Heathrow
American Airlines Logo
7:55 am - 4:25 pmMAN  Manchester-CLT Charlotte Douglas
13h 30m1 stop London Heathrow
$930American Airlines
Wed, Sep 23 - Wed, Sep 30
Virgin Atlantic Logo
12:33 pm - 8:50 amSAV  Savannah/Hilton Head-MAN Manchester
15h 17m1 stop Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
2:55 pm - 5:09 pmMAN  Manchester-SAV Savannah/Hilton Head
31h 14m1 stop New York John F Kennedy Intl
$961Virgin Atlantic
Mon, Sep 7 - Wed, Sep 16

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American Airlines flights from South Carolina to Manchester

Our best American Airlines deals on South Carolina to Manchester flight tickets
American Airlines
Sep 16
CLT6:03 pmCharlotte Douglas
14h 07m
2 stops
MAN1:10 pmManchester
Sep 30
MAN7:55 amManchester
16h 00m
1 stop
CLT6:55 pmCharlotte Douglas
$935
American Airlines
Sep 10
CLT8:25 pmCharlotte Douglas
20h 30m
1 stop
MAN9:55 pmManchester
Sep 24
MAN7:45 amManchester
13h 40m
1 stop
CLT4:25 pmCharlotte Douglas
$991
American Airlines
Sep 10
CLT11:10 pmCharlotte Douglas
17h 45m
1 stop
MAN9:55 pmManchester
Sep 24
MAN7:45 amManchester
16h 13m
2 stops
CLT6:58 pmCharlotte Douglas
$1,001

Brussels Airlines flights from South Carolina to Manchester

Our best Brussels Airlines deals on South Carolina to Manchester flight tickets
Brussels Airlines
Oct 13
GSP2:51 pmGreenville
25h 59m
3 stops
MAN9:50 pmManchester
Nov 4
MAN6:10 amManchester
17h 51m
2 stops
GSP7:01 pmGreenville
$1,238
Brussels Airlines
Aug 27
CHS2:54 pmCharleston
25h 56m
3 stops
MAN9:50 pmManchester
Aug 31
MAN6:05 amManchester
42h 05m
3 stops
CHS7:10 pmCharleston
$3,077

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 1/27

1:45 pm-7:35 am

2 stops12h 50m

Manchester

Mon 2/1

10:00 am-8:45 pm

2 stops15h 45m

$581

Myrtle BeachManchester

MYR Myrtle Beach Intl - MAN Manchester

MYRMAN

Myrtle Beach Intl

Tue 12/8

11:25 am-5:00 pm

2 stops24h 35m

Manchester

Thu 12/10

11:30 am-2:33 pm

2 stops32h 03m

$792

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 1/27

10:30 pm-4:20 pm

1 stop12h 50m

Manchester

Mon 2/1

6:50 pm-2:20 pm

1 stop24h 30m

$868

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Tue 10/27

4:15 pm-11:20 am

2 stops15h 05m

Manchester

Fri 11/6

7:45 am-5:04 pm

2 stops14h 19m

$906

SavannahManchester

SAV Savannah/Hilton Head - MAN Manchester

SAVMAN

Savannah/Hilton Head

Wed 2/3

12:26 pm-8:45 am

1 stop15h 19m

Manchester

Wed 2/10

12:40 pm-11:59 pm

1 stop16h 19m

$917

SavannahManchester

SAV Savannah/Hilton Head - MAN Manchester

SAVMAN

Savannah/Hilton Head

Wed 2/3

11:45 am-10:05 am

2 stops17h 20m

Manchester

Wed 2/10

12:40 pm-8:47 pm

1 stop13h 07m

$922
Quickest round-trip

SavannahManchester

SAV Savannah/Hilton Head - MAN Manchester

SAVMAN

Savannah/Hilton Head

Tue 11/24

2:50 pm-10:30 am

1 stop14h 40m

Manchester

Wed 12/2

12:40 pm-9:15 pm

1 stop13h 35m

$926

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 9/16

11:10 pm-7:05 pm

1 stop14h 55m

Manchester

Wed 9/30

7:05 am-6:55 pm

1 stop16h 50m

$930

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 9/23

11:10 pm-7:05 pm

1 stop14h 55m

Manchester

Wed 9/30

7:55 am-4:25 pm

1 stop13h 30m

$930

SavannahManchester

SAV Savannah/Hilton Head - MAN Manchester

SAVMAN

Savannah/Hilton Head

Mon 9/7

12:33 pm-8:50 am

1 stop15h 17m

Manchester

Wed 9/16

2:55 pm-5:09 pm

1 stop31h 14m

$961

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

The cheapest month to fly to Manchester from South Carolina is in April. Flight prices, which tend to average around $591, are often lower during this time because this is during the off-season. If you don’t want to visit Manchester in April, then you should wait until January to fly from South Carolina, when ticket prices are also cheap, with an average price of $670.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 9% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

10h 15m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 10h 15m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
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Frequently asked questions about flying from South Carolina to Manchester

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Manchester

Compare and see reviews for airlines that fly from South Carolina to Manchester with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $604Free CancellationRating
7.1
11,939 reviews
Search American Airlines flights
Virgin AtlanticPriceFrom $632Free CancellationRating
7.5
694 reviews
Search Virgin Atlantic flights
DeltaPriceFrom $655Free CancellationRating
7.8
8,514 reviews
Search Delta flights

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Sheffield
Ambleside
Windermere
Chester
Leicester
Bradford
Telford
Stoke-on-Trent
Derby
Lancaster
Rochdale
Wilmslow
Cannock
Bolton
Conwy
Preston
Stafford
Salford
Warrington

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

All flight searches from South Carolina to Manchester on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Manchester from South Carolina.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Manchester, momondo offers a useful price alert feature which will track prices for flights to Manchester from South Carolina and alert you when they change.

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