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Cheap flights from South Carolina to Manchester from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 7/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Manchester

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:50 am - 1:30 pm
CLT
-
MAN
24h 40m
2 stops
Multiple Airlines Logo
10:45 pm - 4:20 pm
MAN
-
CLT
22h 35m
2 stops
$548Multiple Airlines
Sun, Mar 29 - Tue, Apr 7
Multiple Airlines Logo
7:50 am - 2:50 pm
CLT
-
MAN
26h 00m
2 stops
Multiple Airlines Logo
10:10 am - 5:55 pm
MAN
-
CLT
35h 45m
2 stops
$610Multiple Airlines
Tue, Mar 3 - Sun, Mar 8
Lufthansa Logo
12:07 pm - 11:20 pm
GSP
-
MAN
30h 13m
2 stops
Lufthansa Logo
11:15 am - 11:59 pm
MAN
-
GSP
16h 44m
2 stops
$614Lufthansa
Thu, Mar 5 - Mon, Mar 9
British Airways Logo
10:58 am - 10:55 am
CHS
-
MAN
18h 57m
2 stops
British Airways Logo
6:10 am - 11:59 pm
MAN
-
CHS
21h 49m
2 stops
$620British Airways
Wed, Mar 4 - Wed, Mar 11
Lufthansa Logo
6:40 pm - 5:05 pm
CLT
-
MAN
17h 25m
1 stop
Lufthansa Logo
7:00 am - 4:45 pm
MAN
-
CLT
14h 45m
1 stop
$626Lufthansa
Tue, May 5 - Thu, May 14
British Airways Logo
5:20 pm - 3:10 pm
CLT
-
MAN
16h 50m
2 stops
British Airways Logo
8:00 pm - 3:05 pm
MAN
-
CLT
24h 05m
2 stops
$627British Airways
Tue, May 5 - Thu, May 14
Delta Logo
10:27 am - 10:30 am
SAV
-
MAN
19h 03m
1 stop
Delta Logo
1:30 pm - 11:59 pm
MAN
-
SAV
14h 29m
1 stop
$627Delta
Wed, Mar 4 - Tue, Mar 10
Virgin Atlantic Logo
3:07 pm - 10:30 am
CHS
-
MAN
14h 23m
1 stop
Virgin Atlantic Logo
1:30 pm - 9:54 pm
MAN
-
CHS
12h 24m
1 stop
$627Virgin Atlantic
Wed, Mar 4 - Wed, Mar 11
Virgin Atlantic Logo
3:07 pm - 10:30 am
CHS
-
MAN
14h 23m
1 stop
Virgin Atlantic Logo
10:25 am - 9:54 pm
MAN
-
CHS
15h 29m
2 stops
$631Virgin Atlantic
Wed, Mar 4 - Wed, Mar 11
Delta Logo
8:40 am - 10:30 am
SAV
-
MAN
20h 50m
1 stop
Delta Logo
5:50 am - 10:03 pm
MAN
-
SAV
20h 13m
2 stops
$637Delta
Wed, Mar 4 - Tue, Mar 10

Lufthansa flights from South Carolina to Manchester

Our best Lufthansa deals on South Carolina to Manchester flight tickets
Lufthansa
Mar 5
GSP12:07 pmGreenville
30h 13m
2 stops
MAN11:20 pmManchester
Mar 9
MAN11:15 amManchester
16h 44m
2 stops
GSP11:59 pmGreenville
$614
Lufthansa
May 5
CLT6:40 pmCharlotte Douglas
17h 25m
1 stop
MAN5:05 pmManchester
May 14
MAN7:00 amManchester
14h 45m
1 stop
CLT4:45 pmCharlotte Douglas
$626
Lufthansa
May 5
CLT6:40 pmCharlotte Douglas
17h 25m
1 stop
MAN5:05 pmManchester
May 14
MAN7:00 amManchester
21h 59m
2 stops
CLT11:59 pmCharlotte Douglas
$635

British Airways flights from South Carolina to Manchester

Our best British Airways deals on South Carolina to Manchester flight tickets
British Airways
Mar 4
CHS10:58 amCharleston
18h 57m
2 stops
MAN10:55 amManchester
Mar 11
MAN6:10 amManchester
21h 49m
2 stops
CHS11:59 pmCharleston
$620
British Airways
May 5
CLT5:20 pmCharlotte Douglas
16h 50m
2 stops
MAN3:10 pmManchester
May 14
MAN8:00 pmManchester
24h 05m
2 stops
CLT3:05 pmCharlotte Douglas
$627
British Airways
May 5
CLT6:18 pmCharlotte Douglas
13h 47m
2 stops
MAN1:05 pmManchester
May 14
MAN10:50 amManchester
16h 02m
2 stops
CLT9:52 pmCharlotte Douglas
$647

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 3/29

7:50 am-1:30 pm

2 stops24h 40m

Manchester

Tue 4/7

10:45 pm-4:20 pm

2 stops22h 35m

$548

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 3/3

7:50 am-2:50 pm

2 stops26h 00m

Manchester

Sun 3/8

10:10 am-5:55 pm

2 stops35h 45m

$610

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 3/5

12:07 pm-11:20 pm

2 stops30h 13m

Manchester

Mon 3/9

11:15 am-11:59 pm

2 stops16h 44m

$614

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/4

10:58 am-10:55 am

2 stops18h 57m

Manchester

Wed 3/11

6:10 am-11:59 pm

2 stops21h 49m

$620

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

6:40 pm-5:05 pm

1 stop17h 25m

Manchester

Thu 5/14

7:00 am-4:45 pm

1 stop14h 45m

$626

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

5:20 pm-3:10 pm

2 stops16h 50m

Manchester

Thu 5/14

8:00 pm-3:05 pm

2 stops24h 05m

$627

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 3/4

10:27 am-10:30 am

1 stop19h 03m

Manchester

Tue 3/10

1:30 pm-11:59 pm

1 stop14h 29m

$627

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/4

3:07 pm-10:30 am

1 stop14h 23m

Manchester

Wed 3/11

1:30 pm-9:54 pm

1 stop12h 24m

$627

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/4

3:07 pm-10:30 am

1 stop14h 23m

Manchester

Wed 3/11

10:25 am-9:54 pm

2 stops15h 29m

$631

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 3/4

8:40 am-10:30 am

1 stop20h 50m

Manchester

Tue 3/10

5:50 am-10:03 pm

2 stops20h 13m

$637

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

The cheapest month to fly to Manchester from South Carolina is in January. Flight prices, which tend to average around $491, are often lower during this time because this is during the off-season. If you don’t want to visit Manchester in January, then you should wait until November to fly from South Carolina, when ticket prices are also cheap, with an average price of $648.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 18% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

13h 39m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 13h 39m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Manchester

Compare and see reviews for airlines that fly from South Carolina to Manchester with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $655Free CancellationRating
7.9
8,164 reviews
Search Delta flights
Virgin AtlanticPriceFrom $655Free CancellationRating
7.5
678 reviews
Search Virgin Atlantic flights

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
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Windermere
Telford
Sheffield
Bradford
Derby
Stoke-on-Trent
Lincoln
Southport
Harrogate
Rochdale
Bolton
Stafford
Sale
Warrington

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

All flight searches from South Carolina to Manchester on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Manchester from South Carolina.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Manchester, momondo offers a useful price alert feature which will track prices for flights to Manchester from South Carolina and alert you when they change.

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