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Cheap flights from Santa Ana, California to Panama from $335

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Ana, California to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:00 pm - 2:14 pm
SNA
-
PTY
20h 14m
2 stops
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$743United Airlines
Mon, Jun 8 - Thu, Jun 25
United Airlines Logo
8:00 am - 6:38 pm
SNA
-
PTY
8h 38m
1 stop
United Airlines Logo
3:41 pm - 1:49 pm
PTY
-
SNA
24h 08m
2 stops
$753United Airlines
Tue, Oct 27 - Fri, Oct 30
United Airlines Logo
6:20 pm - 4:12 pm
SNA
-
PTY
19h 52m
2 stops
United Airlines Logo
3:30 pm - 12:51 pm
PTY
-
SNA
23h 21m
2 stops
$763United Airlines
Mon, Jun 1 - Mon, Jun 8
United Airlines Logo
8:00 am - 6:38 pm
SNA
-
PTY
8h 38m
1 stop
United Airlines Logo
3:41 pm - 2:02 pm
PTY
-
SNA
24h 21m
1 stop
$764United Airlines
Tue, Oct 27 - Fri, Oct 30
United Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$767United Airlines
Sat, Jun 6 - Thu, Jun 25
Copa Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
Copa Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$768Copa Airlines
Wed, Jul 15 - Wed, Jul 29
United Airlines Logo
3:05 pm - 2:14 pm
SNA
-
PTY
21h 09m
1 stop
United Airlines Logo
3:30 pm - 12:51 pm
PTY
-
SNA
23h 21m
2 stops
$769United Airlines
Fri, Jul 17 - Tue, Jul 21
United Airlines Logo
4:00 pm - 4:12 pm
SNA
-
PTY
22h 12m
2 stops
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$771United Airlines
Fri, Jun 12 - Thu, Jun 25
United Airlines Logo
6:26 pm - 4:12 pm
SNA
-
PTY
19h 46m
2 stops
United Airlines Logo
7:55 am - 10:01 pm
PTY
-
SNA
16h 06m
2 stops
$773United Airlines
Mon, Jun 8 - Fri, Jun 26
United Airlines Logo
7:49 pm - 6:37 pm
SNA
-
PTY
20h 48m
2 stops
United Airlines Logo
3:30 pm - 10:59 am
PTY
-
SNA
21h 29m
1 stop
$779United Airlines
Mon, Jun 1 - Mon, Jun 8

Copa Airlines flights from Santa Ana, California to Panama

Our best Copa Airlines deals on Santa Ana, California to Panama flight tickets
Copa Airlines
Jul 15
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 29
PTY7:55 amPanama City Tocumen Intl
15h 50m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$768
Copa Airlines
Sep 16
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 19
PTY10:00 amPanama City Tocumen Intl
13h 53m
1 stop
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$798
Copa Airlines
May 27
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jun 1
PTY3:30 pmPanama City Tocumen Intl
21h 29m
1 stop
SNA10:59 amSanta Ana J. Wayne/Orange Cnty
$892

United Airlines flights from Santa Ana, California to Panama

Our best United Airlines deals on Santa Ana, California to Panama flight tickets
United Airlines
Jun 8
SNA4:00 pmSanta Ana J. Wayne/Orange Cnty
20h 14m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Jun 25
PTY7:55 amPanama City Tocumen Intl
15h 50m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$743
United Airlines
Oct 27
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Oct 30
PTY3:41 pmPanama City Tocumen Intl
24h 08m
2 stops
SNA1:49 pmSanta Ana J. Wayne/Orange Cnty
$753
United Airlines
Jun 1
SNA6:20 pmSanta Ana J. Wayne/Orange Cnty
19h 52m
2 stops
PTY4:12 pmPanama City Tocumen Intl
Jun 8
PTY3:30 pmPanama City Tocumen Intl
23h 21m
2 stops
SNA12:51 pmSanta Ana J. Wayne/Orange Cnty
$763

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

4:00 pm-2:14 pm

2 stops20h 14m

Panama City Tocumen Intl

Thu 6/25

7:55 am-9:45 pm

1 stop15h 50m

$743

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

8:00 am-6:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Fri 10/30

3:41 pm-1:49 pm

2 stops24h 08m

$753

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 6/1

6:20 pm-4:12 pm

2 stops19h 52m

Panama City Tocumen Intl

Mon 6/8

3:30 pm-12:51 pm

2 stops23h 21m

$763

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

8:00 am-6:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Fri 10/30

3:41 pm-2:02 pm

1 stop24h 21m

$764
Quickest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 6/6

7:45 am-6:37 pm

1 stop8h 52m

Panama City Tocumen Intl

Thu 6/25

7:55 am-9:45 pm

1 stop15h 50m

$767

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 7/15

7:45 am-6:37 pm

1 stop8h 52m

Panama City Tocumen Intl

Wed 7/29

7:55 am-9:45 pm

1 stop15h 50m

$768

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Fri 7/17

3:05 pm-2:14 pm

1 stop21h 09m

Panama City Tocumen Intl

Tue 7/21

3:30 pm-12:51 pm

2 stops23h 21m

$769

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Fri 6/12

4:00 pm-4:12 pm

2 stops22h 12m

Panama City Tocumen Intl

Thu 6/25

7:55 am-9:45 pm

1 stop15h 50m

$771

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

6:26 pm-4:12 pm

2 stops19h 46m

Panama City Tocumen Intl

Fri 6/26

7:55 am-10:01 pm

2 stops16h 06m

$773

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 6/1

7:49 pm-6:37 pm

2 stops20h 48m

Panama City Tocumen Intl

Mon 6/8

3:30 pm-10:59 am

1 stop21h 29m

$779

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Santa Ana, California to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Panama?

Copa Airlines and United Airlines are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Panama

What airlines fly to Panama?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Panama from Santa Ana, California according to our data. Copa Airlines is the first choice among our users, with 76% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Santa Ana, California to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama

Fastest flight time

8h 37m

Direct flights

None
The fastest flight from Santa Ana, California to Panama takes 8h 37m
There are no direct flights from Santa Ana, California to Panama. There are no popular flight routes from Santa Ana, California to Panama.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Panama

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama are updated daily.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Panama for you.

Can I find flights from Santa Ana to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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