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Cheap flights from Santa Ana, California to Panama from $331

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santa Ana, California to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:31 pm - 10:30 am
SNA
-
PTY
11h 59m
2 stops
Multiple Airlines Logo
5:30 am - 5:10 pm
PTY
-
SNA
13h 40m
2 stops
$688Multiple Airlines
Thu, Oct 8 - Mon, Oct 12
Multiple Airlines Logo
8:25 pm - 10:30 am
SNA
-
PTY
12h 05m
2 stops
Multiple Airlines Logo
5:30 am - 5:26 pm
PTY
-
SNA
13h 56m
2 stops
$698Multiple Airlines
Mon, Jul 6 - Fri, Jul 10
Multiple Airlines Logo
10:50 am - 1:55 am
SNA
-
PTY
13h 05m
2 stops
Multiple Airlines Logo
3:50 pm - 9:02 am
PTY
-
SNA
19h 12m
2 stops
$743Multiple Airlines
Tue, Jul 7 - Tue, Jul 21
Multiple Airlines Logo
8:25 pm - 1:55 am
SNA
-
PTY
27h 30m
3 stops
Multiple Airlines Logo
5:30 am - 10:30 pm
PTY
-
SNA
19h 00m
2 stops
$770Multiple Airlines
Mon, Jul 6 - Fri, Jul 10
United Airlines Logo
8:00 am - 6:38 pm
SNA
-
PTY
8h 38m
1 stop
United Airlines Logo
7:55 am - 8:45 pm
PTY
-
SNA
14h 50m
2 stops
$772United Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
8:13 am - 6:37 pm
SNA
-
PTY
8h 24m
1 stop
United Airlines Logo
3:30 pm - 3:30 pm
PTY
-
SNA
26h 00m
2 stops
$773United Airlines
Wed, Aug 26 - Tue, Sep 1
United Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$775United Airlines
Mon, Aug 3 - Mon, Aug 10
United Airlines Logo
6:26 pm - 1:45 pm
SNA
-
PTY
17h 19m
2 stops
United Airlines Logo
3:41 pm - 12:04 pm
PTY
-
SNA
22h 23m
2 stops
$776United Airlines
Tue, Oct 27 - Fri, Oct 30
Multiple Airlines Logo
8:25 pm - 1:55 am
SNA
-
PTY
27h 30m
2 stops
Multiple Airlines Logo
5:30 am - 5:26 pm
PTY
-
SNA
13h 56m
2 stops
$777Multiple Airlines
Mon, Aug 3 - Mon, Aug 10
United Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
United Airlines Logo
3:30 pm - 12:50 pm
PTY
-
SNA
23h 20m
2 stops
$779United Airlines
Mon, Aug 3 - Mon, Aug 10

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United Airlines flights from Santa Ana, California to Panama

Our best United Airlines deals on Santa Ana, California to Panama flight tickets
United Airlines
Oct 27
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Oct 31
PTY7:55 amPanama City Tocumen Intl
14h 50m
2 stops
SNA8:45 pmSanta Ana J. Wayne/Orange Cnty
$772
United Airlines
Aug 26
SNA8:13 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 1
PTY3:30 pmPanama City Tocumen Intl
26h 00m
2 stops
SNA3:30 pmSanta Ana J. Wayne/Orange Cnty
$773
United Airlines
Aug 3
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 10
PTY7:55 amPanama City Tocumen Intl
15h 50m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$775

Copa Airlines flights from Santa Ana, California to Panama

Our best Copa Airlines deals on Santa Ana, California to Panama flight tickets
Copa Airlines
Sep 29
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 5
PTY10:00 amPanama City Tocumen Intl
13h 51m
1 stop
SNA9:51 pmSanta Ana J. Wayne/Orange Cnty
$818
Copa Airlines
Aug 13
SNA8:13 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 18
PTY3:30 pmPanama City Tocumen Intl
21h 32m
1 stop
SNA11:02 amSanta Ana J. Wayne/Orange Cnty
$833
Copa Airlines
Aug 3
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 12
PTY3:30 pmPanama City Tocumen Intl
21h 32m
1 stop
SNA11:02 amSanta Ana J. Wayne/Orange Cnty
$836

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Thu 10/8

8:31 pm-10:30 am

2 stops11h 59m

Panama City Tocumen Intl

Mon 10/12

5:30 am-5:10 pm

2 stops13h 40m

$688

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 7/6

8:25 pm-10:30 am

2 stops12h 05m

Panama City Tocumen Intl

Fri 7/10

5:30 am-5:26 pm

2 stops13h 56m

$698

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 7/7

10:50 am-1:55 am

2 stops13h 05m

Panama City Tocumen Intl

Tue 7/21

3:50 pm-9:02 am

2 stops19h 12m

$743

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 7/6

8:25 pm-1:55 am

3 stops27h 30m

Panama City Tocumen Intl

Fri 7/10

5:30 am-10:30 pm

2 stops19h 00m

$770
Quickest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

8:00 am-6:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Sat 10/31

7:55 am-8:45 pm

2 stops14h 50m

$772

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

8:13 am-6:37 pm

1 stop8h 24m

Panama City Tocumen Intl

Tue 9/1

3:30 pm-3:30 pm

2 stops26h 00m

$773

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

7:45 am-6:37 pm

1 stop8h 52m

Panama City Tocumen Intl

Mon 8/10

7:55 am-9:45 pm

1 stop15h 50m

$775

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

6:26 pm-1:45 pm

2 stops17h 19m

Panama City Tocumen Intl

Fri 10/30

3:41 pm-12:04 pm

2 stops22h 23m

$776

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

8:25 pm-1:55 am

2 stops27h 30m

Panama City Tocumen Intl

Mon 8/10

5:30 am-5:26 pm

2 stops13h 56m

$777

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

7:45 am-6:37 pm

1 stop8h 52m

Panama City Tocumen Intl

Mon 8/10

3:30 pm-12:50 pm

2 stops23h 20m

$779

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Santa Ana, California to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Panama?

United Airlines is the most popular carrier operating from Santa Ana J. Wayne/Orange Cnty to Panama

What airlines fly to Panama?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Panama from Santa Ana, California according to our data. Copa Airlines is the first choice among our users, with 78% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Santa Ana, California to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama

Fastest flight time

8h 37m

Direct flights

None
The fastest flight from Santa Ana, California to Panama takes 8h 37m
There are no direct flights from Santa Ana, California to Panama. There are no popular flight routes from Santa Ana, California to Panama.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Panama

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama are updated daily.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Panama for you.

Can I find flights from Santa Ana to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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