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Cheap flights from Santa Ana, California to Panama from $301

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
United Airlines Logo
8:55 am - 9:42 pm
PTY
-
SNA
15h 47m1 stop
$628United Airlines
Mon, Feb 2 - Thu, Feb 5
United Airlines Logo
3:41 pm - 2:45 pm
SNA
-
PTY
20h 04m2 stops
United Airlines Logo
8:55 am - 9:42 pm
PTY
-
SNA
15h 47m1 stop
$632United Airlines
Mon, Feb 2 - Thu, Feb 5
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 11:27 am
PTY
-
SNA
21h 46m1 stop
$641United Airlines
Wed, Feb 4 - Wed, Feb 11
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m1 stop
United Airlines Logo
7:55 am - 9:31 pm
PTY
-
SNA
15h 36m1 stop
$648United Airlines
Sat, Apr 4 - Thu, Apr 9
United Airlines Logo
7:50 pm - 2:45 pm
SNA
-
PTY
15h 55m2 stops
United Airlines Logo
11:35 am - 9:42 pm
PTY
-
SNA
13h 07m1 stop
$672United Airlines
Sun, Jan 25 - Sun, Feb 1
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
United Airlines Logo
8:55 am - 8:42 pm
PTY
-
SNA
14h 47m2 stops
$688United Airlines
Sat, Jan 24 - Sat, Jan 31
United Airlines Logo
4:06 pm - 2:45 pm
SNA
-
PTY
19h 39m2 stops
United Airlines Logo
4:41 pm - 12:15 pm
PTY
-
SNA
22h 34m2 stops
$692United Airlines
Wed, Jan 21 - Sat, Jan 24
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 2:55 pm
PTY
-
SNA
25h 14m2 stops
$712United Airlines
Sat, Jan 10 - Sat, Jan 17
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 11:21 am
PTY
-
SNA
21h 40m1 stop
$722United Airlines
Sat, Jan 10 - Sat, Jan 17
United Airlines Logo
6:40 pm - 7:38 pm
SNA
-
PTY
21h 58m2 stops
United Airlines Logo
4:41 pm - 3:03 pm
PTY
-
SNA
25h 22m2 stops
$742United Airlines
Tue, Dec 23 - Tue, Dec 30

United Airlines flights from Santa Ana, California to Panama

Our best United Airlines deals on Santa Ana, California to Panama flight tickets
United Airlines
Feb 2
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 5
PTY8:55 amPanama City Tocumen Intl
15h 47m
1 stop
SNA9:42 pmSanta Ana J. Wayne/Orange Cnty
$628
Find similar
United Airlines
Feb 2
SNA3:41 pmSanta Ana J. Wayne/Orange Cnty
20h 04m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Feb 5
PTY8:55 amPanama City Tocumen Intl
15h 47m
1 stop
SNA9:42 pmSanta Ana J. Wayne/Orange Cnty
$632
Find similar
United Airlines
Feb 4
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 11
PTY4:41 pmPanama City Tocumen Intl
21h 46m
1 stop
SNA11:27 amSanta Ana J. Wayne/Orange Cnty
$641
Find similar

American Airlines flights from Santa Ana, California to Panama

Our best American Airlines deals on Santa Ana, California to Panama flight tickets
American Airlines
Dec 17
SNA11:41 amSanta Ana J. Wayne/Orange Cnty
23h 12m
2 stops
PTY1:53 pmPanama City Tocumen Intl
Dec 27
PTY4:55 pmPanama City Tocumen Intl
19h 05m
2 stops
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
$902
Find similar
American Airlines
Dec 18
SNA2:47 pmSanta Ana J. Wayne/Orange Cnty
22h 07m
2 stops
PTY3:54 pmPanama City Tocumen Intl
Dec 24
PTY2:53 pmPanama City Tocumen Intl
26h 03m
2 stops
SNA1:56 pmSanta Ana J. Wayne/Orange Cnty
$932
Find similar
American Airlines
Dec 18
SNA2:47 pmSanta Ana J. Wayne/Orange Cnty
22h 07m
2 stops
PTY3:54 pmPanama City Tocumen Intl
Dec 29
PTY2:53 pmPanama City Tocumen Intl
20h 28m
2 stops
SNA8:21 amSanta Ana J. Wayne/Orange Cnty
$952
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Thu 2/5

8:55 am-9:42 pm

1 stop15h 47m

$628

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

3:41 pm-2:45 pm

2 stops20h 04m

Panama City Tocumen Intl

Thu 2/5

8:55 am-9:42 pm

1 stop15h 47m

$632

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Wed 2/11

4:41 pm-11:27 am

1 stop21h 46m

$641

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 4/4

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Thu 4/9

7:55 am-9:31 pm

1 stop15h 36m

$648

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 1/25

7:50 pm-2:45 pm

2 stops15h 55m

Panama City Tocumen Intl

Sun 2/1

11:35 am-9:42 pm

1 stop13h 07m

$672

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Sat 1/31

8:55 am-8:42 pm

2 stops14h 47m

$688

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

4:06 pm-2:45 pm

2 stops19h 39m

Panama City Tocumen Intl

Sat 1/24

4:41 pm-12:15 pm

2 stops22h 34m

$692

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Sat 1/17

4:41 pm-2:55 pm

2 stops25h 14m

$712

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Sat 1/17

4:41 pm-11:21 am

1 stop21h 40m

$722

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 12/23

6:40 pm-7:38 pm

2 stops21h 58m

Panama City Tocumen Intl

Tue 12/30

4:41 pm-3:03 pm

2 stops25h 22m

$742

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Santa Ana, California to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Santa Ana, California. The lowest ticket price found for a Tuesday departure recently was $584. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana, California to Panama for around $1,209.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Santa Ana, California to Panama when you can find flight prices for as low as $584. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $689 per ticket.

Can stopping save me money on Santa Ana, California to Panama flights?

You could potentially save up to 31% on your flight if you consider stops on a Santa Ana, California to Panama flight.

Cheap Santa Ana, California to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama

Fastest flight time

8h 18m

Direct flights

None
The fastest flight from Santa Ana, California to Panama takes 8h 18m
There are no direct flights from Santa Ana, California to Panama. There are no popular flight routes from Santa Ana, California to Panama.
Search flight deals

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Ana, California to Panama

Compare and see reviews for airlines that fly from Santa Ana, California to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $591Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Panama for you.

Can I find flights from Santa Ana to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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