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Cheap flights from Santa Ana, California to Panama from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama departing on 4/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
Copa Airlines Logo
10:00 am - 9:45 pm
PTY
-
SNA
13h 45m
1 stop
$644Copa Airlines
Tue, Apr 7 - Wed, Apr 15
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
7:55 am - 9:00 pm
PTY
-
SNA
15h 05m
2 stops
$649United Airlines
Tue, Apr 28 - Mon, May 4
United Airlines Logo
7:44 pm - 2:14 pm
SNA
-
PTY
16h 30m
2 stops
United Airlines Logo
3:30 pm - 10:20 am
PTY
-
SNA
20h 50m
2 stops
$653United Airlines
Sun, Apr 26 - Mon, May 4
United Airlines Logo
3:29 pm - 2:14 pm
SNA
-
PTY
20h 45m
1 stop
United Airlines Logo
10:00 am - 9:36 pm
PTY
-
SNA
13h 36m
1 stop
$662United Airlines
Mon, Apr 27 - Mon, May 4
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
7:55 am - 9:00 pm
PTY
-
SNA
15h 05m
2 stops
$669United Airlines
Sat, May 2 - Tue, May 5
United Airlines Logo
7:44 pm - 2:14 pm
SNA
-
PTY
16h 30m
2 stops
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
$673United Airlines
Sun, Apr 26 - Sun, May 3
United Airlines Logo
3:29 pm - 2:14 pm
SNA
-
PTY
20h 45m
1 stop
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
$682United Airlines
Mon, Apr 27 - Sun, May 3
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
$689United Airlines
Sun, Apr 26 - Sun, May 3
Multiple Airlines Logo
7:45 am - 10:30 am
SNA
-
PTY
24h 45m
3 stops
Multiple Airlines Logo
3:50 pm - 3:38 pm
PTY
-
SNA
25h 48m
3 stops
$732Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
United Airlines Logo
3:34 pm - 5:07 pm
SNA
-
PTY
22h 33m
1 stop
United Airlines Logo
4:41 pm - 9:45 am
PTY
-
SNA
20h 04m
2 stops
$748United Airlines
Wed, Feb 11 - Mon, Feb 16

United Airlines flights from Santa Ana, California to Panama

Our best United Airlines deals on Santa Ana, California to Panama flight tickets
United Airlines
Apr 28
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
May 4
PTY10:00 amPanama City Tocumen Intl
13h 36m
1 stop
SNA9:36 pmSanta Ana J. Wayne/Orange Cnty
$649
United Airlines
Apr 26
SNA7:44 pmSanta Ana J. Wayne/Orange Cnty
16h 30m
2 stops
PTY2:14 pmPanama City Tocumen Intl
May 4
PTY3:30 pmPanama City Tocumen Intl
20h 50m
2 stops
SNA10:20 amSanta Ana J. Wayne/Orange Cnty
$653
United Airlines
Apr 27
SNA3:29 pmSanta Ana J. Wayne/Orange Cnty
20h 45m
1 stop
PTY2:14 pmPanama City Tocumen Intl
May 4
PTY10:00 amPanama City Tocumen Intl
13h 36m
1 stop
SNA9:36 pmSanta Ana J. Wayne/Orange Cnty
$662

Copa Airlines flights from Santa Ana, California to Panama

Our best Copa Airlines deals on Santa Ana, California to Panama flight tickets
Copa Airlines
Apr 7
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 15
PTY10:00 amPanama City Tocumen Intl
13h 45m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$644
Copa Airlines
Feb 2
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 9
PTY8:55 amPanama City Tocumen Intl
15h 47m
1 stop
SNA9:42 pmSanta Ana J. Wayne/Orange Cnty
$837
Copa Airlines
Jul 15
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 29
PTY7:55 amPanama City Tocumen Intl
15h 58m
1 stop
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$1,893

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 4/7

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Wed 4/15

10:00 am-9:45 pm

1 stop13h 45m

$644

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Mon 5/4

7:55 am-9:00 pm

2 stops15h 05m

$649

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

7:44 pm-2:14 pm

2 stops16h 30m

Panama City Tocumen Intl

Mon 5/4

3:30 pm-10:20 am

2 stops20h 50m

$653

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

3:29 pm-2:14 pm

1 stop20h 45m

Panama City Tocumen Intl

Mon 5/4

10:00 am-9:36 pm

1 stop13h 36m

$662

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 5/2

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Tue 5/5

7:55 am-9:00 pm

2 stops15h 05m

$669

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

7:44 pm-2:14 pm

2 stops16h 30m

Panama City Tocumen Intl

Sun 5/3

7:55 am-9:36 pm

1 stop15h 41m

$673

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

3:29 pm-2:14 pm

1 stop20h 45m

Panama City Tocumen Intl

Sun 5/3

7:55 am-9:36 pm

1 stop15h 41m

$682

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Sun 5/3

7:55 am-9:36 pm

1 stop15h 41m

$689

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 3/15

7:45 am-10:30 am

3 stops24h 45m

Panama City Tocumen Intl

Sun 3/22

3:50 pm-3:38 pm

3 stops25h 48m

$732

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 2/11

3:34 pm-5:07 pm

1 stop22h 33m

Panama City Tocumen Intl

Mon 2/16

4:41 pm-9:45 am

2 stops20h 04m

$748

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Santa Ana, California to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Ana, California to Panama flights?

You could potentially save up to 31% on your flight if you consider stops on a Santa Ana, California to Panama flight.

Cheap Santa Ana, California to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama

Fastest flight time

8h 37m

Direct flights

None
The fastest flight from Santa Ana, California to Panama takes 8h 37m
There are no direct flights from Santa Ana, California to Panama. There are no popular flight routes from Santa Ana, California to Panama.
Search flight deals

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Ana, California to Panama

Compare and see reviews for airlines that fly from Santa Ana, California to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $591Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Panama for you.

Can I find flights from Santa Ana to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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