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Cheap flights from Santa Ana, California to Panama from $301

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:00 pm - 2:14 pmSNA-PTY
20h 14m2 stops
United Airlines Logo
10:00 am - 8:44 amPTY-SNA
24h 44m2 stops
$628United Airlines
Find Deal
Mon, Apr 6 - Wed, Apr 15
United Airlines Logo
8:00 am - 7:38 pmSNA-PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 12:15 pmPTY-SNA
22h 34m2 stops
$632United Airlines
Find Deal
Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
8:00 am - 7:38 pmSNA-PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 11:21 amPTY-SNA
21h 40m1 stop
$641United Airlines
Find Deal
Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
3:34 pm - 2:45 pmSNA-PTY
20h 11m1 stop
United Airlines Logo
11:35 am - 9:45 pmPTY-SNA
12h 10m1 stop
$661United Airlines
Find Deal
Thu, Feb 5 - Thu, Mar 12
United Airlines Logo
8:15 am - 7:38 pmSNA-PTY
8h 23m1 stop
United Airlines Logo
3:35 pm - 9:09 amPTY-SNA
20h 34m1 stop
$668United Airlines
Find Deal
Tue, Dec 9 - Sun, Dec 21
American Airlines Logo
1:27 pm - 1:49 pmSNA-PTY
21h 22m2 stops
American Airlines Logo
2:49 pm - 9:53 amPTY-SNA
22h 04m2 stops
$822American Airlines
Find Deal
Wed, Nov 12 - Fri, Nov 14
American Airlines Logo
11:42 am - 1:49 pmSNA-PTY
23h 07m2 stops
American Airlines Logo
2:49 pm - 1:57 pmPTY-SNA
26h 08m2 stops
$842American Airlines
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Wed, Nov 12 - Sat, Nov 15
Delta Logo
9:20 pm - 2:12 pmSNA-PTY
13h 52m1 stop
Delta Logo
3:37 pm - 11:35 amPTY-SNA
22h 58m1 stop
$1,005Delta
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Sun, Nov 9 - Tue, Nov 11
Multiple Airlines Logo
11:11 am - 12:40 amSNA-PTY
34h 29m3 stops
Multiple Airlines Logo
2:55 am - 10:16 amPTY-SNA
34h 21m3 stops
$1,035Multiple Airlines
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Tue, Dec 23 - Wed, Dec 31
Multiple Airlines Logo
11:11 am - 12:40 amSNA-PTY
34h 29m3 stops
Multiple Airlines Logo
7:50 pm - 10:11 pmPTY-SNA
29h 21m3 stops
$1,340Multiple Airlines
Find Deal
Tue, Dec 23 - Thu, Jan 1

American Airlines flights from Santa Ana, California to Panama

Our best American Airlines deals on Santa Ana, California to Panama flight tickets
American Airlines
Nov 12
SNA1:27 pmSanta Ana J. Wayne/Orange Cnty
21h 22m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 14
PTY2:49 pmPanama City Tocumen Intl
22h 04m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
$822
Find similar
American Airlines
Nov 12
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
23h 07m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 15
PTY2:49 pmPanama City Tocumen Intl
26h 08m
2 stops
SNA1:57 pmSanta Ana J. Wayne/Orange Cnty
$842
Find similar
American Airlines
Nov 12
SNA1:33 pmSanta Ana J. Wayne/Orange Cnty
21h 16m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 16
PTY2:49 pmPanama City Tocumen Intl
22h 04m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
$847
Find similar

United Airlines flights from Santa Ana, California to Panama

Our best United Airlines deals on Santa Ana, California to Panama flight tickets
United Airlines
Apr 6
SNA4:00 pmSanta Ana J. Wayne/Orange Cnty
20h 14m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Apr 15
PTY10:00 amPanama City Tocumen Intl
24h 44m
2 stops
SNA8:44 amSanta Ana J. Wayne/Orange Cnty
$628
Find similar
United Airlines
Jan 13
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 20
PTY4:41 pmPanama City Tocumen Intl
22h 34m
2 stops
SNA12:15 pmSanta Ana J. Wayne/Orange Cnty
$632
Find similar
United Airlines
Jan 13
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 20
PTY4:41 pmPanama City Tocumen Intl
21h 40m
1 stop
SNA11:21 amSanta Ana J. Wayne/Orange Cnty
$641
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 4/6

4:00 pm-2:14 pm

2 stops20h 14m

Panama City Tocumen Intl

Wed 4/15

10:00 am-8:44 am

2 stops24h 44m

$628

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-12:15 pm

2 stops22h 34m

$632

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-11:21 am

1 stop21h 40m

$641

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

3:34 pm-2:45 pm

1 stop20h 11m

Panama City Tocumen Intl

Thu 3/12

11:35 am-9:45 pm

1 stop12h 10m

$661

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

8:15 am-7:38 pm

1 stop8h 23m

Panama City Tocumen Intl

Sun 12/21

3:35 pm-9:09 am

1 stop20h 34m

$668

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 11/12

1:27 pm-1:49 pm

2 stops21h 22m

Panama City Tocumen Intl

Fri 11/14

2:49 pm-9:53 am

2 stops22h 04m

$822

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 11/12

11:42 am-1:49 pm

2 stops23h 07m

Panama City Tocumen Intl

Sat 11/15

2:49 pm-1:57 pm

2 stops26h 08m

$842

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sun 11/9

9:20 pm-2:12 pm

1 stop13h 52m

Panama City Tocumen Intl

Tue 11/11

3:37 pm-11:35 am

1 stop22h 58m

$1,005

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 12/23

11:11 am-12:40 am

3 stops34h 29m

Panama City Tocumen Intl

Wed 12/31

2:55 am-10:16 am

3 stops34h 21m

$1,035

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 12/23

11:11 am-12:40 am

3 stops34h 29m

Panama City Tocumen Intl

Thu 1/1

7:50 pm-10:11 pm

3 stops29h 21m

$1,340

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Santa Ana, California to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Santa Ana, California. The lowest ticket price found for a Tuesday departure recently was $584. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana, California to Panama for around $1,209.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Santa Ana, California to Panama when you can find flight prices for as low as $584. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $689 per ticket.

Can stopping save me money on Santa Ana, California to Panama flights?

You could potentially save up to 17% on your flight if you consider stops on a Santa Ana, California to Panama flight.

Cheap Santa Ana, California to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama

Direct flights

None
There are no direct flights from Santa Ana, California to Panama. There are no popular flight routes from Santa Ana, California to Panama.
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  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Ana, California to Panama

Compare and see reviews for airlines that fly from Santa Ana, California to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $596Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Panama for you.

Can I find flights from Santa Ana to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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