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Cheap flights from San Diego to Panama City from $175

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Copa Airlines Logo
8:12 pm - 5:20 amSAN-PTY
6h 08mnonstop
Copa Airlines Logo
1:45 pm - 5:37 pmPTY-SAN
6h 52mnonstop
$409Copa Airlines
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Wed, Dec 3 - Wed, Dec 10
United Airlines Logo
8:00 pm - 7:38 pmSAN-PTY
20h 38m2 stops
United Airlines Logo
3:35 pm - 8:06 amPTY-SAN
19h 31m1 stop
$424United Airlines
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Fri, Dec 5 - Mon, Dec 15
American Airlines Logo
7:30 pm - 3:42 pmSAN-PTY
17h 12m2 stops
American Airlines Logo
2:50 pm - 9:54 amPTY-SAN
22h 04m2 stops
$428American Airlines
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Sun, Dec 7 - Tue, Dec 16
United Airlines Logo
8:00 am - 7:38 pmSAN-PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 6:36 pmPTY-SAN
28h 55m1 stop
$433United Airlines
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Wed, Jan 7 - Wed, Jan 21
United Airlines Logo
7:50 pm - 2:45 pmSAN-PTY
15h 55m2 stops
United Airlines Logo
3:35 pm - 8:06 amPTY-SAN
19h 31m1 stop
$449United Airlines
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Mon, Nov 17 - Thu, Nov 20
United Airlines Logo
7:50 pm - 6:49 pmSAN-PTY
19h 59m1 stop
United Airlines Logo
4:41 pm - 9:14 amPTY-SAN
19h 33m2 stops
$453United Airlines
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Mon, Nov 17 - Wed, Nov 26
United Airlines Logo
7:50 pm - 7:38 pmSAN-PTY
20h 48m2 stops
United Airlines Logo
3:35 pm - 8:48 pmPTY-SAN
32h 13m1 stop
$455United Airlines
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Mon, Nov 17 - Fri, Nov 21
Copa Airlines Logo
8:10 pm - 5:20 amSAN-PTY
6h 10mnonstop
Copa Airlines Logo
1:15 pm - 5:03 pmPTY-SAN
6h 48mnonstop
$459Copa Airlines
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Mon, Nov 17 - Fri, Nov 21
American Airlines Logo
10:25 pm - 1:27 pmSAN-PTY
12h 02m1 stop
American Airlines Logo
2:52 pm - 8:48 amPTY-SAN
20h 56m2 stops
$483American Airlines
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Mon, Feb 9 - Sun, Feb 15
Delta Logo
10:30 pm - 1:57 pmSAN-PTY
12h 27m1 stop
Delta Logo
3:22 pm - 11:28 pmPTY-SAN
11h 06m1 stop
$600Delta
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Wed, Dec 24 - Fri, Jan 2

American Airlines flights from San Diego to Panama City

Our best American Airlines deals on San Diego to Panama City flight tickets
American Airlines
Dec 7
SAN7:30 pmSan Diego
17h 12m
2 stops
PTY3:42 pmPanama City Tocumen Intl
Dec 16
PTY2:50 pmPanama City Tocumen Intl
22h 04m
2 stops
SAN9:54 amSan Diego
$428
Find similar
American Airlines
Feb 9
SAN10:25 pmSan Diego
12h 02m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 15
PTY2:52 pmPanama City Tocumen Intl
20h 56m
2 stops
SAN8:48 amSan Diego
$483
Find similar
American Airlines
Dec 3
SAN10:35 pmSan Diego
14h 07m
1 stop
PTY3:42 pmPanama City Tocumen Intl
Dec 10
PTY2:50 pmPanama City Tocumen Intl
11h 10m
1 stop
SAN11:00 pmSan Diego
$492
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United Airlines flights from San Diego to Panama City

Our best United Airlines deals on San Diego to Panama City flight tickets
United Airlines
Dec 5
SAN8:00 pmSan Diego
20h 38m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Dec 15
PTY3:35 pmPanama City Tocumen Intl
19h 31m
1 stop
SAN8:06 amSan Diego
$424
Find similar
United Airlines
Jan 7
SAN8:00 amSan Diego
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 21
PTY4:41 pmPanama City Tocumen Intl
28h 55m
1 stop
SAN6:36 pmSan Diego
$433
Find similar
United Airlines
Nov 17
SAN7:50 pmSan Diego
15h 55m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Nov 20
PTY3:35 pmPanama City Tocumen Intl
19h 31m
1 stop
SAN8:06 amSan Diego
$449
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 12/3

8:12 pm-5:20 am

Nonstop6h 08m

Panama City Tocumen Intl

Wed 12/10

1:45 pm-5:37 pm

Nonstop6h 52m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 12/5

8:00 pm-7:38 pm

2 stops20h 38m

Panama City Tocumen Intl

Mon 12/15

3:35 pm-8:06 am

1 stop19h 31m

$424

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 12/7

7:30 pm-3:42 pm

2 stops17h 12m

Panama City Tocumen Intl

Tue 12/16

2:50 pm-9:54 am

2 stops22h 04m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/7

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-6:36 pm

1 stop28h 55m

$433

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 11/17

7:50 pm-2:45 pm

2 stops15h 55m

Panama City Tocumen Intl

Thu 11/20

3:35 pm-8:06 am

1 stop19h 31m

$449

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 11/17

7:50 pm-6:49 pm

1 stop19h 59m

Panama City Tocumen Intl

Wed 11/26

4:41 pm-9:14 am

2 stops19h 33m

$453

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 11/17

7:50 pm-7:38 pm

2 stops20h 48m

Panama City Tocumen Intl

Fri 11/21

3:35 pm-8:48 pm

1 stop32h 13m

$455

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 11/17

8:10 pm-5:20 am

Nonstop6h 10m

Panama City Tocumen Intl

Fri 11/21

1:15 pm-5:03 pm

Nonstop6h 48m

$459

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 2/9

10:25 pm-1:27 pm

1 stop12h 02m

Panama City Tocumen Intl

Sun 2/15

2:52 pm-8:48 am

2 stops20h 56m

$483

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 12/24

10:30 pm-1:57 pm

1 stop12h 27m

Panama City Tocumen Intl

Fri 1/2

3:22 pm-11:28 pm

1 stop11h 06m

$600

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from San Diego to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $388. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from San Diego to Panama City during August average around $410.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $475. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $1,200. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from San Diego to Panama City during this time can be as low as $491. Try not to purchase tickets in the morning because they tend to be around $687. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Diego to Panama City Tocumen Intl flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $552 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Diego for as low as $364 on momondo.

What cabin class options are available on San Diego to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on San Diego to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama City flights?

You could potentially save up to 17% on your flight if you consider stops on a San Diego to Panama City flight.

How have San Diego to Panama City flight prices changed over time?

When to book flights from San Diego to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City (SAN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City

Best Price Found

$198

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Diego in the past 72 hours is $198. The best round-trip flight deal from San Diego to Panama City found on momondo in the last 72 hours is $426.
The fastest flight from San Diego to Panama City takes 6h 02m
Direct flights go from San Diego to Panama City on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is San Diego to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2903.4 mi away from San Diego. 6h 08m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Diego Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama City?

  • What is the most popular airline from San Diego to Panama City?

Best airlines flying from San Diego to Panama City

Compare and see reviews for airlines that fly from San Diego to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $275Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $355Free CancellationRating
7.4
9,004 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $528Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

  • Copa Airlines Flights From San Diego to Panama City

    Copa Airlines operates around 4 flights from San Diego to Panama City every week. The average price of these flights found in the last 72 hours has been $503, but momondo users have found Copa Airlines deals from San Diego to Panama City from as low as $275 round-trip. Copa Airlines has been scored 7.6/10 in 1,561 reviews.

  • United Airlines Flights From San Diego to Panama City

    United Airlines (7.4/10 from 9,003 reviews) operates around 4 flights from San Diego to Panama City in any given week. The average United Airlines airfare for this route is around $613, with deals from around $355 rare but found on momondo. Referenced prices are for round-trip San Diego to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

It is quick and easy to find San Diego to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from San Diego.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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