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Cheap flights from San Diego to Panama City from $236

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:00 am - 7:38 pm
SAN
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 12:59 pm
PTY
-
SAN
23h 18m2 stops
$428United Airlines
Wed, Jan 21 - Mon, Jan 26
United Airlines Logo
8:00 am - 7:38 pm
SAN
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 6:36 pm
PTY
-
SAN
28h 55m1 stop
$433United Airlines
Wed, Jan 21 - Mon, Jan 26
United Airlines Logo
6:55 pm - 2:45 pm
SAN
-
PTY
16h 50m2 stops
United Airlines Logo
4:41 pm - 6:36 pm
PTY
-
SAN
28h 55m1 stop
$438United Airlines
Mon, Jan 19 - Wed, Jan 21
United Airlines Logo
12:11 pm - 2:45 pm
SAN
-
PTY
23h 34m1 stop
United Airlines Logo
4:41 pm - 4:36 pm
PTY
-
SAN
26h 55m1 stop
$443United Airlines
Mon, Jan 19 - Wed, Jan 21
United Airlines Logo
8:37 pm - 7:38 pm
SAN
-
PTY
20h 01m2 stops
United Airlines Logo
4:41 pm - 10:46 am
PTY
-
SAN
21h 05m2 stops
$453United Airlines
Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
8:37 pm - 7:38 pm
SAN
-
PTY
20h 01m2 stops
United Airlines Logo
4:41 pm - 6:36 pm
PTY
-
SAN
28h 55m1 stop
$463United Airlines
Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
1:51 pm - 7:38 pm
SAN
-
PTY
26h 47m1 stop
United Airlines Logo
4:41 pm - 4:36 pm
PTY
-
SAN
26h 55m1 stop
$511United Airlines
Tue, Jan 13 - Tue, Jan 20
American Airlines Logo
4:47 pm - 1:27 pm
SAN
-
PTY
17h 40m2 stops
American Airlines Logo
2:27 pm - 9:04 am
PTY
-
SAN
21h 37m2 stops
$528American Airlines
Thu, Jan 29 - Wed, Feb 4
Multiple Airlines Logo
8:16 pm - 5:20 am
SAN
-
PTY
6h 04mnonstop
Multiple Airlines Logo
2:55 am - 1:57 pm
PTY
-
SAN
38h 02m3 stops
$537Multiple Airlines
Fri, Jan 23 - Wed, Jan 28
Multiple Airlines Logo
8:16 pm - 5:20 am
SAN
-
PTY
6h 04mnonstop
Multiple Airlines Logo
3:50 pm - 11:31 pm
PTY
-
SAN
34h 41m3 stops
$548Multiple Airlines
Fri, Jan 23 - Tue, Jan 27

United Airlines flights from San Diego to Panama City

Our best United Airlines deals on San Diego to Panama City flight tickets
United Airlines
Jan 21
SAN8:37 pmSan Diego
20h 01m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Jan 26
PTY4:41 pmPanama City Tocumen Intl
20h 46m
2 stops
SAN10:27 amSan Diego
$428
Find similar
United Airlines
Jan 21
SAN8:00 amSan Diego
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 26
PTY4:41 pmPanama City Tocumen Intl
28h 55m
1 stop
SAN6:36 pmSan Diego
$433
Find similar
United Airlines
Jan 19
SAN6:55 pmSan Diego
16h 50m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Jan 21
PTY4:41 pmPanama City Tocumen Intl
28h 55m
1 stop
SAN6:36 pmSan Diego
$438
Find similar

American Airlines flights from San Diego to Panama City

Our best American Airlines deals on San Diego to Panama City flight tickets
American Airlines
Jan 29
SAN4:47 pmSan Diego
17h 40m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 4
PTY2:27 pmPanama City Tocumen Intl
21h 37m
2 stops
SAN9:04 amSan Diego
$528
Find similar
American Airlines
Jan 29
SAN10:25 pmSan Diego
12h 02m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 4
PTY2:27 pmPanama City Tocumen Intl
11h 42m
1 stop
SAN11:09 pmSan Diego
$590
Find similar
American Airlines
Jan 6
SAN3:12 pmSan Diego
19h 15m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 14
PTY2:27 pmPanama City Tocumen Intl
22h 33m
2 stops
SAN10:00 amSan Diego
$621
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/21

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-12:59 pm

2 stops23h 18m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/21

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-6:36 pm

1 stop28h 55m

$433

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 1/19

6:55 pm-2:45 pm

2 stops16h 50m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-6:36 pm

1 stop28h 55m

$438

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 1/19

12:11 pm-2:45 pm

1 stop23h 34m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-4:36 pm

1 stop26h 55m

$443

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 1/13

8:37 pm-7:38 pm

2 stops20h 01m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-10:46 am

2 stops21h 05m

$453

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 1/13

8:37 pm-7:38 pm

2 stops20h 01m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-6:36 pm

1 stop28h 55m

$463

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 1/13

1:51 pm-7:38 pm

1 stop26h 47m

Panama City Tocumen Intl

Tue 1/20

4:41 pm-4:36 pm

1 stop26h 55m

$511

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 1/29

4:47 pm-1:27 pm

2 stops17h 40m

Panama City Tocumen Intl

Wed 2/4

2:27 pm-9:04 am

2 stops21h 37m

$528

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 1/23

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

Wed 1/28

2:55 am-1:57 pm

3 stops38h 02m

$537

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 1/23

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

Tue 1/27

3:50 pm-11:31 pm

3 stops34h 41m

$548

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from San Diego to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $388. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from San Diego to Panama City during August average around $423.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $230. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $1,200. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from San Diego to Panama City during this time can be as low as $491. Try not to purchase tickets in the morning because they tend to be around $687. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Diego to Panama City Tocumen Intl flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $539 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Diego for as low as $364 on momondo.

What cabin class options are available on San Diego to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on San Diego to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama City flights?

You could potentially save up to 17% on your flight if you consider stops on a San Diego to Panama City flight.

How have San Diego to Panama City flight prices changed over time?

When to book flights from San Diego to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City (SAN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City

Best Price Found

$209

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Wed, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Diego in the past 72 hours is $209. The best round-trip flight deal from San Diego to Panama City found on momondo in the last 72 hours is $355.
The fastest flight from San Diego to Panama City takes 6h 02m
Direct flights go from San Diego to Panama City on Monday, Tuesday, Wednesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Panama City. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is San Diego to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2903.4 mi away from San Diego. 6h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Diego Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama City?

  • What is the most popular airline from San Diego to Panama City?

Best airlines flying from San Diego to Panama City

Compare and see reviews for airlines that fly from San Diego to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $334Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $355Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $489Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

  • Copa Airlines Flights From San Diego to Panama City

    Copa Airlines operates around 5 flights from San Diego to Panama City every week. The average price of these flights found in the last 72 hours has been $520, but momondo users have found Copa Airlines deals from San Diego to Panama City from as low as $334 round-trip. Copa Airlines has been scored 7.6/10 in 1,556 reviews.

  • United Airlines Flights From San Diego to Panama City

    United Airlines (7.4/10 from 9,091 reviews) operates around 5 flights from San Diego to Panama City in any given week. The average United Airlines airfare for this route is around $607, with deals from around $355 rare but found on momondo. Referenced prices are for round-trip San Diego to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

It is quick and easy to find San Diego to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from San Diego.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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