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Cheap flights from San Diego to Panama City from $363

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
10:30 pm - 12:58 pmSAN  San Diego-PTY Panama City Tocumen Intl
12h 28m1 stop Atlanta Hartsfield-Jackson
JetBlue Logo
2:23 pm - 10:54 pmPTY  Panama City Tocumen Intl-SAN San Diego
10h 31m1 stop Atlanta Hartsfield-Jackson
$497JetBlue
Fri, Sep 25 - Fri, Oct 2
Copa Airlines Logo
10:00 pm - 6:13 amSAN  San Diego-PTY Panama City Tocumen Intl
6h 13mnonstop
Copa Airlines Logo
1:45 pm - 5:15 pmPTY  Panama City Tocumen Intl-SAN San Diego
6h 30mnonstop
$550Copa Airlines
Wed, Oct 28 - Mon, Nov 2
Copa Airlines Logo
10:00 pm - 6:13 amSAN  San Diego-PTY Panama City Tocumen Intl
6h 13mnonstop
Copa Airlines Logo
1:45 pm - 6:27 pmPTY  Panama City Tocumen Intl-SAN San Diego
6h 42mnonstop
$550Copa Airlines
Mon, Oct 19 - Mon, Oct 26
Copa Airlines Logo
10:00 pm - 6:17 amSAN  San Diego-PTY Panama City Tocumen Intl
6h 17mnonstop
Copa Airlines Logo
1:54 pm - 6:29 pmPTY  Panama City Tocumen Intl-SAN San Diego
6h 35mnonstop
$550Copa Airlines
Fri, Sep 18 - Fri, Sep 25
United Airlines Logo
6:50 pm - 6:37 pmSAN  San Diego-PTY Panama City Tocumen Intl
21h 47m2 stops Denver Intl Houston George Bush Intcntl
United Airlines Logo
3:30 pm - 9:05 amPTY  Panama City Tocumen Intl-SAN San Diego
19h 35m2 stops Houston George Bush Intcntl Denver Intl
$556United Airlines
Fri, Sep 25 - Fri, Oct 2
United Airlines Logo
7:41 pm - 6:37 pmSAN  San Diego-PTY Panama City Tocumen Intl
20h 56m2 stops San Francisco Houston George Bush Intcntl
United Airlines Logo
10:00 am - 12:31 amPTY  Panama City Tocumen Intl-SAN San Diego
16h 31m2 stops Houston George Bush Intcntl San Francisco
$556United Airlines
Fri, Sep 25 - Fri, Oct 2
American Airlines Logo
10:30 pm - 12:16 pmSAN  San Diego-PTY Panama City Tocumen Intl
11h 46m1 stop Miami
American Airlines Logo
2:02 pm - 10:43 pmPTY  Panama City Tocumen Intl-SAN San Diego
10h 41m1 stop Miami
$565American Airlines
Thu, Oct 1 - Thu, Oct 15
American Airlines Logo
10:30 pm - 12:16 pmSAN  San Diego-PTY Panama City Tocumen Intl
11h 46m1 stop Miami
American Airlines Logo
2:02 pm - 10:43 pmPTY  Panama City Tocumen Intl-SAN San Diego
10h 41m1 stop Miami
$565American Airlines
Fri, Oct 2 - Fri, Oct 9
Delta Logo
10:30 pm - 12:58 pmSAN  San Diego-PTY Panama City Tocumen Intl
12h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:23 pm - 10:54 pmPTY  Panama City Tocumen Intl-SAN San Diego
10h 31m1 stop Atlanta Hartsfield-Jackson
$565Delta
Tue, Sep 22 - Mon, Oct 5
Delta Logo
9:45 pm - 12:58 pmSAN  San Diego-PTY Panama City Tocumen Intl
13h 13m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:23 pm - 10:54 pmPTY  Panama City Tocumen Intl-SAN San Diego
10h 31m1 stop Atlanta Hartsfield-Jackson
$565Delta
Sun, Sep 27 - Fri, Oct 2

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Delta flights from San Diego to Panama City

Our best Delta deals on San Diego to Panama City flight tickets
Delta
Sep 24
SAN2:00 pmSan Diego
20h 58m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Oct 5
PTY2:23 pmPanama City Tocumen Intl
10h 31m
1 stop
SAN10:54 pmSan Diego
$578
Delta
Oct 10
SAN2:10 pmSan Diego
20h 49m
1 stop
PTY12:59 pmPanama City Tocumen Intl
Oct 16
PTY2:24 pmPanama City Tocumen Intl
21h 18m
1 stop
SAN9:42 amSan Diego
$592
Delta
Dec 2
SAN10:30 pmSan Diego
12h 33m
1 stop
PTY2:03 pmPanama City Tocumen Intl
Dec 10
PTY3:29 pmPanama City Tocumen Intl
21h 27m
1 stop
SAN9:56 amSan Diego
$601

American Airlines flights from San Diego to Panama City

Our best American Airlines deals on San Diego to Panama City flight tickets
American Airlines
Oct 2
SAN12:08 pmSan Diego
22h 08m
2 stops
PTY12:16 pmPanama City Tocumen Intl
Oct 9
PTY2:02 pmPanama City Tocumen Intl
24h 10m
2 stops
SAN12:12 pmSan Diego
$570
American Airlines
Sep 20
SAN10:30 pmSan Diego
11h 46m
1 stop
PTY12:16 pmPanama City Tocumen Intl
Sep 27
PTY1:16 pmPanama City Tocumen Intl
21h 02m
2 stops
SAN8:18 amSan Diego
$574
American Airlines
Oct 2
SAN10:30 pmSan Diego
11h 46m
1 stop
PTY12:16 pmPanama City Tocumen Intl
Oct 4
PTY1:16 pmPanama City Tocumen Intl
24h 40m
1 stop
SAN11:56 amSan Diego
$586

momondo Fare Finder

 
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

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Route

Depart

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Price

Cheapest round-trip

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Fri 9/25

10:30 pm-12:58 pm

1 stop12h 28m

Panama City Tocumen Intl

Fri 10/2

2:23 pm-10:54 pm

1 stop10h 31m

$497
Quickest round-trip

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Wed 10/28

10:00 pm-6:13 am

Nonstop6h 13m

Panama City Tocumen Intl

Mon 11/2

1:45 pm-5:15 pm

Nonstop6h 30m

$550

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Mon 10/19

10:00 pm-6:13 am

Nonstop6h 13m

Panama City Tocumen Intl

Mon 10/26

1:45 pm-6:27 pm

Nonstop6h 42m

$550

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Fri 9/18

10:00 pm-6:17 am

Nonstop6h 17m

Panama City Tocumen Intl

Fri 9/25

1:54 pm-6:29 pm

Nonstop6h 35m

$550

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Fri 9/25

6:50 pm-6:37 pm

2 stops21h 47m

Panama City Tocumen Intl

Fri 10/2

3:30 pm-9:05 am

2 stops19h 35m

$556

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Fri 9/25

7:41 pm-6:37 pm

2 stops20h 56m

Panama City Tocumen Intl

Fri 10/2

10:00 am-12:31 am

2 stops16h 31m

$556

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Thu 10/1

10:30 pm-12:16 pm

1 stop11h 46m

Panama City Tocumen Intl

Thu 10/15

2:02 pm-10:43 pm

1 stop10h 41m

$565

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Fri 10/2

10:30 pm-12:16 pm

1 stop11h 46m

Panama City Tocumen Intl

Fri 10/9

2:02 pm-10:43 pm

1 stop10h 41m

$565

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Tue 9/22

10:30 pm-12:58 pm

1 stop12h 28m

Panama City Tocumen Intl

Mon 10/5

2:23 pm-10:54 pm

1 stop10h 31m

$565

San DiegoPanama City

SAN San Diego - PTY Panama City Tocumen Intl

SANPTY

San Diego

Sun 9/27

9:45 pm-12:58 pm

1 stop13h 13m

Panama City Tocumen Intl

Fri 10/2

2:23 pm-10:54 pm

1 stop10h 31m

$565

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Panama City?

Prices are currently typical for flights on this route.

Typical prices usually range from $486 to $730.
The lowest price recently found on this route was $497.

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from San Diego to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $439. If you’re not able to fly to Panama City in October, then November is your next best option. Flight prices from San Diego to Panama City during November average around $453.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $544. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $1,194. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest San Diego to Panama City Tocumen Intl flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from San Diego to Panama City?

You are more likely to see cheaper flights to Panama City from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $664 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Diego for as low as $279 on momondo.

What cabin class options are available on San Diego to Panama City flights?

There are 3 cabin classes available to choose from on San Diego to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama City flights?

You could potentially save up to 11% on your flight if you consider stops on a San Diego to Panama City flight.

How have San Diego to Panama City flight prices changed over time?

As of August 2026, prices for San Diego to Panama City flights are approximately 3% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City (SAN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City

Best Price Found

$363

Fastest flight time

6h 01m

Direct flights

Mon, Tue, Thu, Sat and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Diego in the past 72 hours is $363. The best round-trip flight deal from San Diego to Panama City found on momondo in the last 72 hours is $497.
The fastest flight from San Diego to Panama City takes 6h 01m
Direct flights go from San Diego to Panama City on Monday, Tuesday, Thursday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from San Diego to Panama City

  • How far is San Diego to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2903.4 mi away from San Diego. 6h 01m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Diego Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama City?

  • What is the most popular airline from San Diego to Panama City?

Best airlines flying from San Diego to Panama City

Compare and see reviews for airlines that fly from San Diego to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $279Free CancellationRating
7.4
10,114 reviews
Search United Airlines flights
American AirlinesPriceFrom $309Free CancellationRating
7.1
11,981 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $365Free CancellationRating
7.6
1,553 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From San Diego to Panama City

    Copa Airlines operates around 3 flights from San Diego to Panama City every week. The average price of these flights found in the last 72 hours has been $667, but momondo users have found Copa Airlines deals from San Diego to Panama City from as low as $365 round-trip. Copa Airlines has been scored 7.6/10 in 1,553 reviews.

  • United Airlines Flights From San Diego to Panama City

    United Airlines (7.4/10 from 10,113 reviews) operates around 4 flights from San Diego to Panama City in any given week. The average United Airlines airfare for this route is around $704, with deals from around $279 rare but found on momondo. Referenced prices are for round-trip San Diego to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

It is quick and easy to find San Diego to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from San Diego.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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