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Cheap flights from San Diego to Panama City from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Copa Airlines Logo
9:12 pm - 5:25 amSAN-PTY
6h 13mnonstop
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
$389Copa Airlines
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Mon, Oct 13 - Mon, Oct 20
United Airlines Logo
7:20 pm - 2:14 pmSAN-PTY
16h 54m2 stops
United Airlines Logo
3:35 pm - 12:15 amPTY-SAN
10h 40m1 stop
$403United Airlines
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Sat, Sep 27 - Sun, Oct 5
United Airlines Logo
5:55 pm - 2:45 pmSAN-PTY
17h 50m3 stops
United Airlines Logo
4:41 pm - 9:14 amPTY-SAN
19h 33m2 stops
$408United Airlines
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Fri, Nov 7 - Sat, Nov 22
Copa Airlines Logo
9:08 pm - 5:25 amSAN-PTY
6h 17mnonstop
Copa Airlines Logo
1:15 pm - 5:50 pmPTY-SAN
6h 35mnonstop
$424Copa Airlines
Find Deal
Fri, Sep 19 - Sun, Sep 28
United Airlines Logo
5:56 pm - 2:14 pmSAN-PTY
42h 18m3 stops
United Airlines Logo
3:30 pm - 7:56 amPTY-SAN
18h 26m2 stops
$429United Airlines
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Wed, Sep 24 - Thu, Oct 2
Copa Airlines Logo
9:08 pm - 5:25 amSAN-PTY
6h 17mnonstop
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
$441Copa Airlines
Find Deal
Mon, Sep 22 - Fri, Oct 3
Delta Logo
8:00 am - 8:01 pmSAN-PTY
9h 01m1 stop
Delta Logo
3:17 pm - 10:58 pmPTY-SAN
10h 41m1 stop
$461Delta
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Fri, Nov 28 - Wed, Dec 10
United Airlines Logo
6:00 pm - 6:38 pmSAN-PTY
22h 38m3 stops
United Airlines Logo
3:35 pm - 12:13 amPTY-SAN
11h 38m1 stop
$466United Airlines
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Sat, Oct 25 - Sun, Nov 2
American Airlines Logo
10:17 pm - 2:30 pmSAN-PTY
14h 13m1 stop
American Airlines Logo
2:40 pm - 12:23 amPTY-SAN
12h 43m1 stop
$513American Airlines
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Sun, Aug 31 - Mon, Dec 22
American Airlines Logo
10:54 pm - 2:30 pmSAN-PTY
13h 36m2 stops
American Airlines Logo
2:40 pm - 12:23 amPTY-SAN
12h 43m1 stop
$518American Airlines
Find Deal
Sun, Aug 31 - Mon, Dec 22

United Airlines flights from San Diego to Panama City

Our best United Airlines deals on San Diego to Panama City flight tickets
United Airlines
Sep 27
SAN7:20 pmSan Diego
16h 54m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Oct 5
PTY3:35 pmPanama City Tocumen Intl
10h 40m
1 stop
SAN12:15 amSan Diego
$403
Find similar
United Airlines
Nov 7
SAN5:55 pmSan Diego
17h 50m
3 stops
PTY2:45 pmPanama City Tocumen Intl
Nov 22
PTY4:41 pmPanama City Tocumen Intl
19h 33m
2 stops
SAN9:14 amSan Diego
$408
Find similar
United Airlines
Sep 24
SAN5:56 pmSan Diego
42h 18m
3 stops
PTY2:14 pmPanama City Tocumen Intl
Oct 2
PTY3:30 pmPanama City Tocumen Intl
18h 26m
2 stops
SAN7:56 amSan Diego
$429
Find similar

American Airlines flights from San Diego to Panama City

Our best American Airlines deals on San Diego to Panama City flight tickets
American Airlines
Aug 31
SAN10:17 pmSan Diego
14h 13m
1 stop
PTY2:30 pmPanama City Tocumen Intl
Dec 22
PTY2:40 pmPanama City Tocumen Intl
12h 43m
1 stop
SAN12:23 amSan Diego
$513
Find similar
American Airlines
Aug 31
SAN10:54 pmSan Diego
13h 36m
2 stops
PTY2:30 pmPanama City Tocumen Intl
Dec 22
PTY2:40 pmPanama City Tocumen Intl
12h 43m
1 stop
SAN12:23 amSan Diego
$518
Find similar
American Airlines
Aug 2
SAN10:45 pmSan Diego
13h 30m
2 stops
PTY2:15 pmPanama City Tocumen Intl
Aug 26
PTY3:30 pmPanama City Tocumen Intl
22h 54m
2 stops
SAN12:24 pmSan Diego
$564
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momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 10/13

9:12 pm-5:25 am

Nonstop6h 13m

Panama City Tocumen Intl

Mon 10/20

1:15 pm-5:57 pm

Nonstop6h 42m

$389

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 9/27

7:20 pm-2:14 pm

2 stops16h 54m

Panama City Tocumen Intl

Sun 10/5

3:35 pm-12:15 am

1 stop10h 40m

$403

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/7

5:55 pm-2:45 pm

3 stops17h 50m

Panama City Tocumen Intl

Sat 11/22

4:41 pm-9:14 am

2 stops19h 33m

$408

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/19

9:08 pm-5:25 am

Nonstop6h 17m

Panama City Tocumen Intl

Sun 9/28

1:15 pm-5:50 pm

Nonstop6h 35m

$424

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 9/24

5:56 pm-2:14 pm

3 stops42h 18m

Panama City Tocumen Intl

Thu 10/2

3:30 pm-7:56 am

2 stops18h 26m

$429

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 9/22

9:08 pm-5:25 am

Nonstop6h 17m

Panama City Tocumen Intl

Fri 10/3

1:15 pm-5:57 pm

Nonstop6h 42m

$441

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/28

8:00 am-8:01 pm

1 stop9h 01m

Panama City Tocumen Intl

Wed 12/10

3:17 pm-10:58 pm

1 stop10h 41m

$461

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 10/25

6:00 pm-6:38 pm

3 stops22h 38m

Panama City Tocumen Intl

Sun 11/2

3:35 pm-12:13 am

1 stop11h 38m

$466

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 8/31

10:17 pm-2:30 pm

1 stop14h 13m

Panama City Tocumen Intl

Mon 12/22

2:40 pm-12:23 am

1 stop12h 43m

$513

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 8/31

10:54 pm-2:30 pm

2 stops13h 36m

Panama City Tocumen Intl

Mon 12/22

2:40 pm-12:23 am

1 stop12h 43m

$518

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from San Diego to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $388. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from San Diego to Panama City during August average around $460.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $480. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $649. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from San Diego to Panama City during this time can be as low as $506. Try not to purchase tickets in the morning because they tend to be around $687. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Diego to Panama City Tocumen Intl flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $600 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Diego for as low as $346 on momondo.

What cabin class options are available on San Diego to Panama City Tocumen Intl flights?

There are 2 cabin classes available to choose from on San Diego to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama City flights?

No. A direct flight is the cheapest option for a flight between San Diego to Panama City.

How have San Diego to Panama City flight prices changed over time?

When to book flights from San Diego to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City (SAN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City

Best Price Found

$165

Fastest flight time

6h 04m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Diego in the past 72 hours is $165. The best round-trip flight deal from San Diego to Panama City found on momondo in the last 72 hours is $389.
The fastest flight from San Diego to Panama City takes 6h 04m
Direct flights go from San Diego to Panama City on Monday, Tuesday, Thursday and Saturday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is San Diego to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2903.4 mi away from San Diego. 6h 04m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Diego Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama City?

  • What is the most popular airline from San Diego to Panama City?

Best airlines flying from San Diego to Panama City

Compare and see reviews for airlines that fly from San Diego to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $224Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
DeltaPriceFrom $355Free CancellationRating
8.0
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $403Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
American AirlinesPriceFrom $586Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Copa Airlines Flights From San Diego to Panama City

    Copa Airlines operates around 4 flights from San Diego to Panama City every week. The average price of these flights found in the last 72 hours has been $443, but momondo users have found Copa Airlines deals from San Diego to Panama City from as low as $224 round-trip. Copa Airlines has been scored 7.5/10 in 1,493 reviews.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

It is quick and easy to find San Diego to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from San Diego.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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