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Cheap flights from San Diego to Panama City from $240

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 2/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:18 pm - 5:20 am
SAN
-
PTY
6h 02mnonstop
Copa Airlines Logo
1:33 pm - 6:30 pm
PTY
-
SAN
6h 57mnonstop
$546Copa Airlines
Fri, Apr 24 - Sun, Apr 26
Multiple Airlines Logo
10:02 pm - 1:55 am
SAN
-
PTY
25h 53m
2 stops
Multiple Airlines Logo
5:30 am - 8:45 pm
PTY
-
SAN
17h 15m
2 stops
$550Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
10:05 pm - 12:46 pm
SAN
-
PTY
12h 41m
1 stop
American Airlines Logo
1:49 pm - 8:38 am
PTY
-
SAN
20h 49m
2 stops
$553American Airlines
Sat, Apr 18 - Mon, Apr 20
Multiple Airlines Logo
6:52 am - 2:55 pm
SAN
-
PTY
30h 03m
3 stops
Multiple Airlines Logo
5:30 am - 9:29 pm
PTY
-
SAN
17h 59m
2 stops
$554Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
United Airlines Logo
6:15 am - 6:37 pm
SAN
-
PTY
10h 22m
1 stop
United Airlines Logo
10:00 am - 8:04 pm
PTY
-
SAN
12h 04m
1 stop
$561United Airlines
Tue, May 12 - Thu, May 14
United Airlines Logo
8:39 pm - 2:14 pm
SAN
-
PTY
15h 35m
2 stops
United Airlines Logo
7:55 am - 8:12 pm
PTY
-
SAN
14h 17m
2 stops
$565United Airlines
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
9:25 pm - 2:55 pm
SAN
-
PTY
39h 30m
3 stops
Multiple Airlines Logo
5:30 am - 9:29 pm
PTY
-
SAN
17h 59m
2 stops
$566Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
Multiple Airlines Logo
10:25 am - 2:55 pm
SAN
-
PTY
26h 30m
3 stops
Multiple Airlines Logo
3:50 pm - 8:34 pm
PTY
-
SAN
30h 44m
2 stops
$571Multiple Airlines
Fri, May 8 - Tue, May 12
United Airlines Logo
5:00 pm - 4:12 pm
SAN
-
PTY
21h 12m
1 stop
United Airlines Logo
7:55 am - 9:24 pm
PTY
-
SAN
15h 29m
1 stop
$573United Airlines
Thu, Jul 2 - Thu, Jul 9
Copa Airlines Logo
5:00 pm - 2:14 pm
SAN
-
PTY
19h 14m
1 stop
Copa Airlines Logo
3:30 pm - 10:20 am
PTY
-
SAN
20h 50m
2 stops
$575Copa Airlines
Fri, Apr 3 - Sat, Apr 11

American Airlines flights from San Diego to Panama City

Our best American Airlines deals on San Diego to Panama City flight tickets
American Airlines
Apr 18
SAN10:05 pmSan Diego
12h 41m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 20
PTY1:49 pmPanama City Tocumen Intl
20h 49m
2 stops
SAN8:38 amSan Diego
$553
American Airlines
Apr 24
SAN12:53 pmSan Diego
21h 53m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 27
PTY1:49 pmPanama City Tocumen Intl
22h 20m
2 stops
SAN10:09 amSan Diego
$581
American Airlines
Apr 24
SAN12:53 pmSan Diego
21h 53m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 27
PTY1:49 pmPanama City Tocumen Intl
24h 04m
1 stop
SAN11:53 amSan Diego
$592

Copa Airlines flights from San Diego to Panama City

Our best Copa Airlines deals on San Diego to Panama City flight tickets
Copa Airlines
Apr 24
SAN9:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
Apr 26
PTY1:33 pmPanama City Tocumen Intl
6h 57m
SAN6:30 pmSan Diego
$546
Copa Airlines
Apr 3
SAN5:00 pmSan Diego
19h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Apr 11
PTY3:30 pmPanama City Tocumen Intl
20h 50m
2 stops
SAN10:20 amSan Diego
$575
Copa Airlines
Mar 16
SAN9:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
Mar 23
PTY1:15 pmPanama City Tocumen Intl
6h 59m
SAN6:14 pmSan Diego
$632

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/24

9:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Sun 4/26

1:33 pm-6:30 pm

Nonstop6h 57m

$546

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 4/9

10:02 pm-1:55 am

2 stops25h 53m

Panama City Tocumen Intl

Mon 4/13

5:30 am-8:45 pm

2 stops17h 15m

$550

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 4/18

10:05 pm-12:46 pm

1 stop12h 41m

Panama City Tocumen Intl

Mon 4/20

1:49 pm-8:38 am

2 stops20h 49m

$553

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/24

6:52 am-2:55 pm

3 stops30h 03m

Panama City Tocumen Intl

Mon 4/27

5:30 am-9:29 pm

2 stops17h 59m

$554

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 5/12

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Thu 5/14

10:00 am-8:04 pm

1 stop12h 04m

$561

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/24

8:39 pm-2:14 pm

2 stops15h 35m

Panama City Tocumen Intl

Mon 4/27

7:55 am-8:12 pm

2 stops14h 17m

$565

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 4/23

9:25 pm-2:55 pm

3 stops39h 30m

Panama City Tocumen Intl

Mon 4/27

5:30 am-9:29 pm

2 stops17h 59m

$566

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 5/8

10:25 am-2:55 pm

3 stops26h 30m

Panama City Tocumen Intl

Tue 5/12

3:50 pm-8:34 pm

2 stops30h 44m

$571

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 7/2

5:00 pm-4:12 pm

1 stop21h 12m

Panama City Tocumen Intl

Thu 7/9

7:55 am-9:24 pm

1 stop15h 29m

$573

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/3

5:00 pm-2:14 pm

1 stop19h 14m

Panama City Tocumen Intl

Sat 4/11

3:30 pm-10:20 am

2 stops20h 50m

$575

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from San Diego to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $388. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from San Diego to Panama City during August average around $439.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $230. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $1,200. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest San Diego to Panama City Tocumen Intl flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $548 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Diego for as low as $384 on momondo.

What cabin class options are available on San Diego to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on San Diego to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama City flights?

No. A direct flight is the cheapest option for a flight between San Diego to Panama City.

How have San Diego to Panama City flight prices changed over time?

As of February 2026, prices for San Diego to Panama City flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City (SAN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City

Best Price Found

$270

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Diego in the past 72 hours is $270. The best round-trip flight deal from San Diego to Panama City found on momondo in the last 72 hours is $440.
The fastest flight from San Diego to Panama City takes 6h 02m
Direct flights go from San Diego to Panama City on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Panama City. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is San Diego to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2903.4 mi away from San Diego. 6h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Diego Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama City?

  • What is the most popular airline from San Diego to Panama City?

Best airlines flying from San Diego to Panama City

Compare and see reviews for airlines that fly from San Diego to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $234Free CancellationRating
7.5
1,556 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $279Free CancellationRating
7.4
9,254 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
8,172 reviews
Search Delta flights
American AirlinesPriceFrom $489Free CancellationRating
7.2
11,249 reviews
Search American Airlines flights

  • Copa Airlines Flights From San Diego to Panama City

    Copa Airlines operates around 4 flights from San Diego to Panama City every week. The average price of these flights found in the last 72 hours has been $532, but momondo users have found Copa Airlines deals from San Diego to Panama City from as low as $234 round-trip. Copa Airlines has been scored 7.5/10 in 1,556 reviews.

  • United Airlines Flights From San Diego to Panama City

    United Airlines (7.4/10 from 9,254 reviews) operates around 4 flights from San Diego to Panama City in any given week. The average United Airlines airfare for this route is around $585, with deals from around $279 rare but found on momondo. Referenced prices are for round-trip San Diego to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

It is quick and easy to find San Diego to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from San Diego.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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