Which layover airport offers the lowest fares from Quito to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $467.

Which layover airport has the shortest travel time from Quito to Santiago?

Flights connecting via Guayaquil (GYE) have the shortest average one-way travel time: 6h 53m.

Which layover airport has the shortest connection time from Quito to Santiago?

Panama City (PTY) has the shortest average layover time for this route: 0h 50m.

What is the most punctual flight time for Quito to Santiago flights?

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

What airlines fly to Santiago?

LATAM Airlines, Avianca and JetSMART are the top three most popular airlines that fly to Santiago from Quito according to our data. LATAM Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

What day of the week experiences the fewest flight delays on this route?

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Tuesday has historically seen more delays on average compared to the rest of the week.

Which airport is the most popular layover for flights between Quito and Santiago?

Lima (LIM) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

How often are flights from Quito to Santiago delayed?

Historically, on average around 0% of flights between Quito and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

What is the cheapest airline that flies from Quito Mariscal Sucr to Santiago Arturo Merino Benitez?

JetSMART is the most popular carrier operating from Quito Mariscal Sucr to Santiago Arturo Merino Benitez

When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of February 2026.

How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$235 Cheap Flights from Quito to Santiago in 2026

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Find the cheapest flights from Quito to Santiago

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$335JetSMART

Sun, May 31 - Sun, Jun 7

4:49 pm - 5:14 am

UIO

SCL

10h 25m

1 stop

8:31 am - 4:04 pm

SCL

UIO

8h 33m

1 stop

$336JetSMART

Wed, Mar 25 - Fri, Jun 5

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$348JetSMART

Wed, Jun 24 - Sun, Jun 28

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:41 am - 4:04 pm

SCL

UIO

12h 23m

1 stop

$355JetSMART

Wed, Apr 8 - Wed, Apr 15

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$360JetSMART

Wed, May 20 - Sun, May 31

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$374JetSMART

Fri, May 15 - Sun, May 31

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$375JetSMART

Fri, Apr 10 - Sun, Apr 12

4:49 pm - 5:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$378JetSMART

Fri, Apr 3 - Sun, Apr 12

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$383JetSMART

Fri, May 15 - Fri, May 29

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$389JetSMART

Fri, May 1 - Sun, May 10

JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets

JetSMART

May 31

UIO4:49 pmQuito Mariscal Sucr

10h 27m

1 stop

SCL4:16 amSantiago Arturo Merino Benitez

Jun 7

SCL4:56 amSantiago Arturo Merino Benitez

12h 08m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$335

JetSMART

Mar 25

UIO4:49 pmQuito Mariscal Sucr

10h 25m

1 stop

SCL5:14 amSantiago Arturo Merino Benitez

Jun 5

SCL8:31 amSantiago Arturo Merino Benitez

8h 33m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$336

JetSMART

Jun 24

UIO4:49 pmQuito Mariscal Sucr

10h 27m

1 stop

SCL4:16 amSantiago Arturo Merino Benitez

Jun 28

SCL4:56 amSantiago Arturo Merino Benitez

12h 08m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$348

Copa Airlines flights from Quito to Santiago

Our best Copa Airlines deals on Quito to Santiago flight tickets

Copa Airlines

Mar 4

UIO12:27 pmQuito Mariscal Sucr

10h 07m

1 stop

SCL12:34 amSantiago Arturo Merino Benitez

Mar 9

SCL5:21 amSantiago Arturo Merino Benitez

9h 30m

1 stop

UIO12:51 pmQuito Mariscal Sucr

$633

Copa Airlines

Mar 6

UIO2:32 pmQuito Mariscal Sucr

11h 26m

1 stop

SCL3:58 amSantiago Arturo Merino Benitez

Mar 12

SCL5:21 amSantiago Arturo Merino Benitez

10h 48m

1 stop

UIO2:09 pmQuito Mariscal Sucr

$742

Copa Airlines

Mar 5

UIO2:32 pmQuito Mariscal Sucr

10h 45m

1 stop

SCL3:17 amSantiago Arturo Merino Benitez

Mar 11

SCL3:32 amSantiago Arturo Merino Benitez

11h 19m

1 stop

UIO12:51 pmQuito Mariscal Sucr

$748

Fly from

Fly to

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 5/31

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Sun 6/7

4:56 am-4:04 pm

1 stop12h 08m

$335

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 3/25

4:49 pm-5:14 am

1 stop10h 25m

Santiago Arturo Merino Benitez

Fri 6/5

8:31 am-4:04 pm

1 stop8h 33m

$336

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 6/24

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Sun 6/28

4:56 am-4:04 pm

1 stop12h 08m

$348

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 4/8

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Wed 4/15

4:41 am-4:04 pm

1 stop12h 23m

$355

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 5/20

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Sun 5/31

4:56 am-4:04 pm

1 stop12h 08m

$360

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/15

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 5/31

4:56 am-4:04 pm

1 stop12h 08m

$374

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 4/10

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 4/12

4:56 am-4:04 pm

1 stop12h 08m

$375

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 4/3

4:49 pm-5:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 4/12

4:56 am-4:04 pm

1 stop12h 08m

$378

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/15

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 5/29

4:56 am-4:04 pm

1 stop12h 08m

$383

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 5/10

4:56 am-4:04 pm

1 stop12h 08m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

What is the typical price of a round-trip flight between Quito and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $260. If you don’t want to visit Santiago in April, then you should wait until June to fly from Quito, when ticket prices are also cheap, with an average price of $277.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $329 on momondo.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of February 2026, prices for Quito to Santiago flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Fastest flight time	7h 30m
Direct flights	None

The fastest flight from Quito to Santiago takes 7h 30m

There are no direct flights from Quito to Santiago. There are no popular flight routes from Quito to Santiago.

Search flight deals

How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 7h 30m.
When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of February 2026.
How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Quito to Santiago?
momondo data reveals that the most frequently booked airline on the route from Quito to Santiago is LATAM Airlines, representing 54% of all bookings. The subsequent popular airlines are Avianca at 19%, JetSMART at 17%, and Copa Airlines at 10%.

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo

Airline	Rating	Free Cancellation	Price
JetSMART	PriceFrom $133	Free Cancellation	Rating 6.7 272 reviews	Search JetSMART flights
Avianca	PriceFrom $183	Free Cancellation	Rating 6.6 2,496 reviews	Search Avianca flights
Copa Airlines	PriceFrom $275	Free Cancellation	Rating 7.5 1,555 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $343	Free Cancellation	Rating 7.5 1,921 reviews	Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.