Which layover airport has the shortest connection time from Quito to Santiago?

Panama City (PTY) has the shortest average layover time for this route: 0h 50m.

Which layover airport offers the lowest fares from Quito to Santiago?

Flights via Lima (LIM) offer the lowest average round-trip price of $459.

What airlines fly to Santiago?

LATAM Airlines, JetSMART and Avianca are the top three most popular airlines that fly to Santiago from Quito according to our data. LATAM Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Quito and Santiago?

Lima (LIM) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Quito Mariscal Sucr to Santiago Arturo Merino Benitez?

JetSMART and Avianca are the most popular carriers operating from Quito Mariscal Sucr to Santiago Arturo Merino Benitez

Which layover airport has the shortest travel time from Quito to Santiago?

Flights connecting via Guayaquil (GYE) have the shortest average one-way travel time: 6h 53m.

When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of July 2026.

How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$241 Cheap Flights from Quito to Santiago in 2026

Q: What is the typical price of a round-trip flight between Quito and Santiago?

Prices are currently typical for flights on this route. Typical prices usually range from $323 to $580. The lowest price recently found on this route was $381.

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Quito to Santiago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$381JetSMART

Wed, Aug 26 - Mon, Aug 31

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$388JetSMART

Wed, Aug 26 - Mon, Aug 31

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$398JetSMART

Fri, Aug 14 - Mon, Aug 31

4:49 pm - 3:56 am

UIO

SCL

10h 07m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$406JetSMART

Mon, Aug 24 - Mon, Aug 31

4:49 pm - 4:16 am

UIO

SCL

10h 27m

1 stop

4:41 am - 4:04 pm

SCL

UIO

12h 23m

1 stop

$414JetSMART

Wed, Aug 19 - Wed, Aug 26

4:49 pm - 3:56 am

UIO

SCL

10h 07m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$416JetSMART

Mon, Aug 24 - Sun, Aug 30

4:49 pm - 3:56 am

UIO

SCL

10h 07m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$425JetSMART

Mon, Aug 24 - Sun, Aug 30

4:49 pm - 3:56 am

UIO

SCL

10h 07m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$431JetSMART

Mon, Aug 24 - Sun, Aug 30

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:41 am - 4:04 pm

SCL

UIO

12h 23m

1 stop

$440JetSMART

Sun, Aug 16 - Wed, Aug 19

4:49 pm - 4:11 am

UIO

SCL

10h 22m

1 stop

4:56 am - 4:04 pm

SCL

UIO

12h 08m

1 stop

$441JetSMART

Sun, Aug 16 - Mon, Aug 31

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets

JetSMART

Aug 26

UIO4:49 pmQuito Mariscal Sucr

10h 27m

1 stop

SCL4:16 amSantiago Arturo Merino Benitez

Aug 31

SCL4:56 amSantiago Arturo Merino Benitez

12h 08m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$381

JetSMART

Aug 26

UIO4:49 pmQuito Mariscal Sucr

10h 27m

1 stop

SCL4:16 amSantiago Arturo Merino Benitez

Aug 31

SCL4:56 amSantiago Arturo Merino Benitez

12h 08m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$388

JetSMART

Aug 14

UIO4:49 pmQuito Mariscal Sucr

10h 22m

1 stop

SCL4:11 amSantiago Arturo Merino Benitez

Aug 31

SCL4:56 amSantiago Arturo Merino Benitez

12h 08m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$398

LATAM Airlines flights from Quito to Santiago

Our best LATAM Airlines deals on Quito to Santiago flight tickets

LATAM Airlines

Jul 16

UIO12:15 pmQuito Mariscal Sucr

14h 10m

1 stop

SCL3:25 amSantiago Arturo Merino Benitez

Jul 20

SCL7:55 pmSantiago Arturo Merino Benitez

8h 20m

1 stop

UIO3:15 amQuito Mariscal Sucr

$632

LATAM Airlines

Jul 20

UIO8:20 pmQuito Mariscal Sucr

14h 26m

2 stops

SCL11:46 amSantiago Arturo Merino Benitez

Jul 27

SCL2:50 pmSantiago Arturo Merino Benitez

13h 25m

1 stop

UIO3:15 amQuito Mariscal Sucr

$642

LATAM Airlines

Jul 16

UIO7:06 amQuito Mariscal Sucr

15h 19m

2 stops

SCL11:25 pmSantiago Arturo Merino Benitez

Jul 20

SCL7:55 pmSantiago Arturo Merino Benitez

8h 20m

1 stop

UIO3:15 amQuito Mariscal Sucr

$652

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 8/26

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Mon 8/31

4:56 am-4:04 pm

1 stop12h 08m

$381

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 8/26

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Mon 8/31

4:56 am-4:04 pm

1 stop12h 08m

$388

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 8/14

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Mon 8/31

4:56 am-4:04 pm

1 stop12h 08m

$398

Quickest round-trip

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 8/24

4:49 pm-3:56 am

1 stop10h 07m

Santiago Arturo Merino Benitez

Mon 8/31

4:56 am-4:04 pm

1 stop12h 08m

$406

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 8/19

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Wed 8/26

4:41 am-4:04 pm

1 stop12h 23m

$414

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 8/24

4:49 pm-3:56 am

1 stop10h 07m

Santiago Arturo Merino Benitez

Sun 8/30

4:56 am-4:04 pm

1 stop12h 08m

$416

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 8/24

4:49 pm-3:56 am

1 stop10h 07m

Santiago Arturo Merino Benitez

Sun 8/30

4:56 am-4:04 pm

1 stop12h 08m

$425

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 8/24

4:49 pm-3:56 am

1 stop10h 07m

Santiago Arturo Merino Benitez

Sun 8/30

4:56 am-4:04 pm

1 stop12h 08m

$431

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 8/16

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Wed 8/19

4:41 am-4:04 pm

1 stop12h 23m

$440

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 8/16

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Mon 8/31

4:56 am-4:04 pm

1 stop12h 08m

$441

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Quito and Santiago?

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $359. If you don’t want to visit Santiago in June, then you should wait until April to fly from Quito, when ticket prices are also cheap, with an average price of $364.

How far in advance should I book a flight from Quito to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $416 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $370 on momondo.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 15% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of July 2026, prices for Quito to Santiago flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Fastest flight time	4h 00m
Direct flights	Fri and Sun
Airports in Santiago	1 airport

The fastest flight from Quito to Santiago takes 4h 00m

Direct flights go from Quito to Santiago on Friday and Sunday. There are no airlines offering direct flights.

There is 1 airport in Santiago. From Quito there are direct flights to Santiago Arturo Merino Benitez (SCL).

Search flight deals

Frequently asked questions about flying from Quito to Santiago

How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 4h 00m.
When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of July 2026.
How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Quito to Santiago?
momondo data reveals that the most frequently booked airline on the route from Quito to Santiago is LATAM Airlines, representing 52% of all bookings. The subsequent popular airlines are JetSMART at 22%, Avianca at 16%, and Copa Airlines at 10%.

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo

Airline	Rating	Free Cancellation	Price
JetSMART	PriceFrom $166	Free Cancellation	Rating 6.8 317 reviews	Search JetSMART flights
Avianca	PriceFrom $194	Free Cancellation	Rating 6.5 2,520 reviews	Search Avianca flights
Copa Airlines	PriceFrom $275	Free Cancellation	Rating 7.6 1,568 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $341	Free Cancellation	Rating 7.4 1,949 reviews	Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.