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Cheap flights from Quito to Santiago from $201

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Quito to Santiago departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Quito to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
JetSMART Logo
4:56 am - 4:04 pm
SCL
-
UIO
12h 08m
1 stop
$268JetSMART
Fri, May 1 - Fri, May 8
JetSMART Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
JetSMART Logo
4:56 am - 4:04 pm
SCL
-
UIO
12h 08m
1 stop
$320JetSMART
Fri, May 1 - Sun, May 10
Multiple Airlines Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
Multiple Airlines Logo
2:30 pm - 10:25 pm
SCL
-
UIO
8h 55m
1 stop
$325Multiple Airlines
Fri, May 1 - Thu, May 7
Multiple Airlines Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
Multiple Airlines Logo
2:30 pm - 10:25 pm
SCL
-
UIO
8h 55m
1 stop
$326Multiple Airlines
Fri, May 1 - Tue, May 12
JetSMART Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
JetSMART Logo
4:56 am - 4:04 pm
SCL
-
UIO
12h 08m
1 stop
$351JetSMART
Fri, May 15 - Sun, May 31
Multiple Airlines Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
Multiple Airlines Logo
6:10 am - 2:40 pm
SCL
-
UIO
9h 30m
1 stop
$354Multiple Airlines
Fri, May 1 - Sat, May 9
JetSMART Logo
4:49 pm - 5:16 am
UIO
-
SCL
10h 27m
1 stop
JetSMART Logo
4:56 am - 4:04 pm
SCL
-
UIO
12h 08m
1 stop
$355JetSMART
Wed, Apr 1 - Fri, May 1
JetSMART Logo
4:49 pm - 4:11 am
UIO
-
SCL
10h 22m
1 stop
JetSMART Logo
4:56 am - 4:04 pm
SCL
-
UIO
12h 08m
1 stop
$356JetSMART
Sun, Apr 19 - Sun, May 3
JetSMART Logo
4:49 pm - 5:14 am
UIO
-
SCL
10h 25m
1 stop
JetSMART Logo
5:59 am - 4:00 pm
SCL
-
UIO
12h 01m
1 stop
$357JetSMART
Wed, Mar 18 - Wed, Mar 25
JetSMART Logo
4:49 pm - 10:39 am
UIO
-
SCL
15h 50m
1 stop
JetSMART Logo
5:59 am - 4:00 pm
SCL
-
UIO
12h 01m
1 stop
$361JetSMART
Wed, Mar 18 - Sun, Mar 22

JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets
JetSMART
May 1
UIO4:49 pmQuito Mariscal Sucr
10h 22m
1 stop
SCL4:11 amSantiago Arturo Merino Benitez
May 8
SCL4:56 amSantiago Arturo Merino Benitez
12h 08m
1 stop
UIO4:04 pmQuito Mariscal Sucr
$268
JetSMART
May 1
UIO4:49 pmQuito Mariscal Sucr
10h 22m
1 stop
SCL4:11 amSantiago Arturo Merino Benitez
May 10
SCL4:56 amSantiago Arturo Merino Benitez
12h 08m
1 stop
UIO4:04 pmQuito Mariscal Sucr
$320
JetSMART
May 15
UIO4:49 pmQuito Mariscal Sucr
10h 22m
1 stop
SCL4:11 amSantiago Arturo Merino Benitez
May 31
SCL4:56 amSantiago Arturo Merino Benitez
12h 08m
1 stop
UIO4:04 pmQuito Mariscal Sucr
$351

LATAM Airlines flights from Quito to Santiago

Our best LATAM Airlines deals on Quito to Santiago flight tickets
LATAM Airlines
May 11
UIO6:00 amQuito Mariscal Sucr
10h 25m
2 stops
SCL5:25 pmSantiago Arturo Merino Benitez
May 11
SCL8:30 pmSantiago Arturo Merino Benitez
15h 40m
2 stops
UIO11:10 amQuito Mariscal Sucr
$474
LATAM Airlines
Feb 3
UIO12:15 pmQuito Mariscal Sucr
14h 15m
1 stop
SCL4:30 amSantiago Arturo Merino Benitez
Feb 7
SCL8:15 amSantiago Arturo Merino Benitez
16h 45m
2 stops
UIO11:00 pmQuito Mariscal Sucr
$606
LATAM Airlines
Feb 2
UIO6:45 pmQuito Mariscal Sucr
18h 45m
2 stops
SCL3:30 pmSantiago Arturo Merino Benitez
Feb 6
SCL8:50 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
UIO11:05 amQuito Mariscal Sucr
$628

momondo Fare Finder

 
Customize your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Fri 5/8

4:56 am-4:04 pm

1 stop12h 08m

$268

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 5/10

4:56 am-4:04 pm

1 stop12h 08m

$320

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Thu 5/7

2:30 pm-10:25 pm

1 stop8h 55m

$325

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Tue 5/12

2:30 pm-10:25 pm

1 stop8h 55m

$326

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/15

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 5/31

4:56 am-4:04 pm

1 stop12h 08m

$351

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/1

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sat 5/9

6:10 am-2:40 pm

1 stop9h 30m

$354

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 4/1

4:49 pm-5:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Fri 5/1

4:56 am-4:04 pm

1 stop12h 08m

$355

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 4/19

4:49 pm-4:11 am

1 stop10h 22m

Santiago Arturo Merino Benitez

Sun 5/3

4:56 am-4:04 pm

1 stop12h 08m

$356

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 3/18

4:49 pm-5:14 am

1 stop10h 25m

Santiago Arturo Merino Benitez

Wed 3/25

5:59 am-4:00 pm

1 stop12h 01m

$357

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 3/18

4:49 pm-10:39 am

1 stop15h 50m

Santiago Arturo Merino Benitez

Sun 3/22

5:59 am-4:00 pm

1 stop12h 01m

$361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Quito and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $254. If you don’t want to visit Santiago in April, then you should wait until May to fly from Quito, when ticket prices are also cheap, with an average price of $272.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $324 on momondo.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 9% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of January 2026, prices for Quito to Santiago flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Fastest flight time

10h 10m

Direct flights

None
The fastest flight from Quito to Santiago takes 10h 10m
There are no direct flights from Quito to Santiago. There are no popular flight routes from Quito to Santiago.
Search flight deals

  • How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 10h 10m.

  • When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Quito to Santiago?

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo
Airline
Rating
Free Cancellation
Price
JetSMARTPriceFrom $161Free CancellationRating
6.7
261 reviews
Search JetSMART flights
AviancaPriceFrom $183Free CancellationRating
6.6
2,496 reviews
Search Avianca flights
Copa AirlinesPriceFrom $275Free CancellationRating
7.6
1,557 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $354Free CancellationRating
7.5
1,913 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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