Which layover airport has the shortest travel time from Quito to Santiago?

Flights connecting via Guayaquil (GYE) have the shortest average one-way travel time: 6h 53m.

Which airport is the most popular layover for flights between Quito and Santiago?

Lima (LIM) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Quito to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $467.

Which layover airport has the shortest connection time from Quito to Santiago?

Panama City (PTY) has the shortest average layover time for this route: 0h 50m.

What airlines fly to Santiago?

LATAM Airlines, JetSMART and Avianca are the top three most popular airlines that fly to Santiago from Quito according to our data. LATAM Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Quito Mariscal Sucr to Santiago Arturo Merino Benitez?

JetSMART and LATAM Airlines are the most popular carriers operating from Quito Mariscal Sucr to Santiago Arturo Merino Benitez

When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of November 2026.

How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$190 Cheap Flights from Quito to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Quito to Santiago

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Cheap round-trip flights

Enter your travel dates to find the best prices.

4:50 pm - 5:05 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 15m1 stop Lima J Chavez Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$328JetSMART

Wed, Dec 9 - Fri, Dec 25

4:50 pm - 5:05 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 15m1 stop Lima J Chavez Intl

6:07 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 57m1 stop Lima J Chavez Intl

$336JetSMART

Wed, Dec 2 - Mon, Jan 25

6:46 am - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 35m1 stop Guayaquil Jose Joaquin de Olmedo

6:07 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 57m1 stop Lima J Chavez Intl

$444Multiple Airlines

Thu, Mar 11 - Mon, Mar 15

6:46 am - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 35m1 stop Guayaquil Jose Joaquin de Olmedo

6:07 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 57m1 stop Lima J Chavez Intl

$448Multiple Airlines

Thu, Mar 11 - Mon, Mar 15

6:18 am - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 03m1 stop Guayaquil Jose Joaquin de Olmedo

5:55 pm - 1:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 00m1 stop Lima J Chavez Intl

$549LATAM Airlines

Tue, Dec 1 - Tue, Dec 8

1:29 pm - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

8h 52m1 stop Guayaquil Jose Joaquin de Olmedo

7:25 pm - 10:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

4h 45mnonstop

$549LATAM Airlines

Tue, Dec 1 - Tue, Dec 8

10:40 am - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

17h 05m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

12:30 am - 1:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

13h 35m1 stop Bogotá El Dorado

$560Avianca

Wed, Apr 14 - Sun, Apr 18

1:40 pm - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

14h 05m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

4:15 pm - 1:10 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 55m1 stop Bogotá El Dorado

$583Avianca

Fri, Jan 1 - Mon, Feb 15

6:32 pm - 8:11 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

23h 39m1 stop Panama City Tocumen Intl

12:20 pm - 12:36 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

26h 16m1 stop Panama City Tocumen Intl

$626Copa Airlines

Tue, Dec 1 - Wed, Dec 9

6:32 pm - 5:52 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

9h 20m1 stop Panama City Tocumen Intl

12:20 pm - 12:36 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

26h 16m1 stop Panama City Tocumen Intl

$626Copa Airlines

Wed, Dec 2 - Mon, Dec 7

Cheap last minute flights

Enter your travel dates to find the best prices.

12:35 pm - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 10m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

7:30 am - 5:45 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 15m1 stop Bogotá El Dorado

$560Avianca

Fri, Nov 6 - Fri, Nov 13

12:35 pm - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 10m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

2:10 am - 2:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

14h 00m1 stop Bogotá El Dorado

$560Avianca

Fri, Nov 6 - Thu, Nov 12

8:35 pm - 3:10 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 35m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

7:30 am - 5:45 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 15m1 stop Bogotá El Dorado

$560Avianca

Fri, Nov 6 - Fri, Nov 13

3:20 pm - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

12h 25m1 stop Bogotá El Dorado

2:10 am - 2:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

14h 00m1 stop Bogotá El Dorado

$571Avianca

Fri, Nov 6 - Thu, Nov 12

6:36 pm - 8:15 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

23h 39m1 stop Panama City Tocumen Intl

1:26 am - 12:32 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

25h 06m1 stop Panama City Tocumen Intl

$654Copa Airlines

Wed, Nov 4 - Sun, Nov 8

6:36 pm - 11:36 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

27h 00m1 stop Panama City Tocumen Intl

1:02 am - 11:32 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

24h 30m1 stop Panama City Tocumen Intl

$654Copa Airlines

Wed, Nov 4 - Sat, Nov 7

6:36 pm - 11:36 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

27h 00m1 stop Panama City Tocumen Intl

1:02 am - 11:32 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

24h 30m1 stop Panama City Tocumen Intl

$654Copa Airlines

Wed, Nov 4 - Sat, Nov 7

4:50 pm - 11:41 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 51m3 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl Buenos Aires Jorge Newbery

4:10 am - 11:00 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

20h 50m2 stops Lima J Chavez Intl Bogotá El Dorado

$1,037LATAM Airlines

Fri, Nov 6 - Thu, Nov 12

4:50 pm - 11:41 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 51m3 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl Buenos Aires Jorge Newbery

4:10 am - 11:00 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

20h 50m2 stops Lima J Chavez Intl Bogotá El Dorado

$1,142LATAM Airlines

Fri, Nov 6 - Thu, Nov 12

4:50 pm - 11:41 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 51m3 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl Buenos Aires Jorge Newbery

4:10 am - 11:00 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

20h 50m2 stops Lima J Chavez Intl Bogotá El Dorado

$1,340LATAM Airlines

Fri, Nov 6 - Thu, Nov 12

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JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets

JetSMART

Dec 9

UIO4:50 pmQuito Mariscal Sucr

10h 15m

1 stop

SCL5:05 amSantiago Arturo Merino Benitez

Dec 25

SCL6:07 amSantiago Arturo Merino Benitez

11h 58m

1 stop

UIO4:05 pmQuito Mariscal Sucr

$328

JetSMART

Dec 2

UIO4:50 pmQuito Mariscal Sucr

10h 15m

1 stop

SCL5:05 amSantiago Arturo Merino Benitez

Jan 25

SCL6:07 amSantiago Arturo Merino Benitez

11h 57m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$336

JetSMART

Mar 5

UIO4:51 pmQuito Mariscal Sucr

16h 02m

1 stop

SCL10:53 amSantiago Arturo Merino Benitez

Mar 12

SCL6:07 amSantiago Arturo Merino Benitez

11h 52m

1 stop

UIO3:59 pmQuito Mariscal Sucr

$337

Copa Airlines flights from Quito to Santiago

Our best Copa Airlines deals on Quito to Santiago flight tickets

Copa Airlines

Nov 12

UIO6:36 pmQuito Mariscal Sucr

27h 48m

1 stop

SCL12:24 amSantiago Arturo Merino Benitez

Nov 17

SCL3:48 amSantiago Arturo Merino Benitez

10h 46m

1 stop

UIO12:34 pmQuito Mariscal Sucr

$602

Copa Airlines

Nov 12

UIO6:36 pmQuito Mariscal Sucr

9h 10m

1 stop

SCL5:46 amSantiago Arturo Merino Benitez

Nov 16

SCL1:02 amSantiago Arturo Merino Benitez

13h 32m

1 stop

UIO12:34 pmQuito Mariscal Sucr

$644

Copa Airlines

Nov 4

UIO6:36 pmQuito Mariscal Sucr

23h 39m

1 stop

SCL8:15 pmSantiago Arturo Merino Benitez

Nov 8

SCL1:26 amSantiago Arturo Merino Benitez

25h 06m

1 stop

UIO12:32 amQuito Mariscal Sucr

$654

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 12/9

4:50 pm-5:05 am

1 stop10h 15m

Santiago Arturo Merino Benitez

Fri 12/25

6:07 am-4:05 pm

1 stop11h 58m

$328

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 12/2

4:50 pm-5:05 am

1 stop10h 15m

Santiago Arturo Merino Benitez

Mon 1/25

6:07 am-4:04 pm

1 stop11h 57m

$336

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Thu 3/11

6:46 am-12:21 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Mon 3/15

6:07 am-4:04 pm

1 stop11h 57m

$444

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Thu 3/11

6:46 am-12:21 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Mon 3/15

6:07 am-4:04 pm

1 stop11h 57m

$448

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Tue 12/1

6:18 am-12:21 am

1 stop16h 03m

Santiago Arturo Merino Benitez

Tue 12/8

5:55 pm-1:55 am

1 stop10h 00m

$549

Quickest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Tue 12/1

1:29 pm-12:21 am

1 stop8h 52m

Santiago Arturo Merino Benitez

Tue 12/8

7:25 pm-10:10 pm

Nonstop4h 45m

$549

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 4/14

10:40 am-4:45 am

2 stops17h 05m

Santiago Arturo Merino Benitez

Sun 4/18

12:30 am-1:05 pm

1 stop13h 35m

$560

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 1/1

1:40 pm-5:45 am

2 stops14h 05m

Santiago Arturo Merino Benitez

Mon 2/15

4:15 pm-1:10 am

1 stop10h 55m

$583

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Tue 12/1

6:32 pm-8:11 pm

1 stop23h 39m

Santiago Arturo Merino Benitez

Wed 12/9

12:20 pm-12:36 pm

1 stop26h 16m

$626

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 12/2

6:32 pm-5:52 am

1 stop9h 20m

Santiago Arturo Merino Benitez

Mon 12/7

12:20 pm-12:36 pm

1 stop26h 16m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Quito and Santiago?

Prices are currently typical for flights on this route.

Typical prices usually range from $274 to $533.
The lowest price recently found on this route was $328.

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you don’t want to visit Santiago in April, then you should wait until June to fly from Quito, when ticket prices are also cheap, with an average price of $363.

What is the cheapest Quito Mariscal Sucr to Santiago Arturo Merino Benitez flight route?

Fly from Quito Mariscal Sucr to Santiago Arturo Merino Benitez for the best Quito Mariscal Sucr - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight from Quito to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $410 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $362 on momondo.

What cabin class options are available on Quito to Santiago flights?

There is only 1 cabin class available to choose from on Quito to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 18% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of November 2026, prices for Quito to Santiago flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Best Price Found	$190
Fastest flight time	5h 00m
Direct flights	Mon, Wed, Fri and Sun
Airports in Santiago	1 airport

The best one-way flight to Santiago from Quito in the past 72 hours is $190. The best round-trip flight deal from Quito to Santiago found on momondo in the last 72 hours is $328.

The fastest flight from Quito to Santiago takes 5h 00m

Direct flights go from Quito to Santiago on Monday, Wednesday, Friday and Sunday. The only airline offering direct flights is LATAM Airlines.

There is 1 airport in Santiago. From Quito there are direct flights to Santiago Arturo Merino Benitez (SCL).

Search flight deals

Frequently asked questions about flying from Quito to Santiago

How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 5h 00m.
When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of November 2026.
How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Quito to Santiago?
Based on momondo bookings for flights between Quito and Santiago, the leading plane model is Airbus A320-100/200, making up 100.00% of the total bookings.
What is the most popular airline from Quito to Santiago?
momondo data reveals that the most frequently booked airline on the route from Quito to Santiago is LATAM Airlines, representing 47% of all bookings. The subsequent popular airlines are JetSMART at 30%, Avianca at 14%, and Copa Airlines at 9%.

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo

Airline	Rating	Free Cancellation	Price
JetSMART	PriceFrom $182	Free Cancellation	Rating 6.9 350 reviews	Search JetSMART flights
LATAM Airlines	PriceFrom $221	Free Cancellation	Rating 7.4 1,968 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $275	Free Cancellation	Rating 7.6 1,552 reviews	Search Copa Airlines flights
Avianca	PriceFrom $286	Free Cancellation	Rating 6.5 2,549 reviews	Search Avianca flights

Viña del Mar

Valparaíso

Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.