Which layover airport has the shortest connection time from Quito to Santiago?

Panama City (PTY) has the shortest average layover time for this route: 0h 50m.

What airlines fly to Santiago?

LATAM Airlines, JetSMART and Avianca are the top three most popular airlines that fly to Santiago from Quito according to our data. LATAM Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Quito to Santiago?

Flights connecting via Guayaquil (GYE) have the shortest average one-way travel time: 6h 53m.

What is the cheapest airline that flies from Quito Mariscal Sucr to Santiago Arturo Merino Benitez?

JetSMART is the most popular carrier operating from Quito Mariscal Sucr to Santiago Arturo Merino Benitez

Which airport is the most popular layover for flights between Quito and Santiago?

Lima (LIM) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Quito to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $467.

When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of October 2026.

How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$263 Cheap Flights from Quito to Santiago in 2026/27

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Find the cheapest flights from Quito to Santiago

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Cheap round-trip flights

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11:00 am - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

11h 21m1 stop Guayaquil Jose Joaquin de Olmedo

5:55 pm - 1:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 00m1 stop Lima J Chavez Intl

$443LATAM Airlines

Mon, Mar 15 - Mon, Mar 22

4:50 pm - 5:05 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 15m1 stop Lima J Chavez Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$455JetSMART

Wed, Dec 2 - Sun, Dec 6

4:50 pm - 5:05 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 15m1 stop Lima J Chavez Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$471JetSMART

Fri, Nov 27 - Wed, Dec 2

4:50 pm - 10:53 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 03m1 stop Lima J Chavez Intl

7:00 pm - 9:45 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

4h 45mnonstop

$520Multiple Airlines

Wed, Mar 10 - Tue, Mar 16

4:49 pm - 4:16 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 27m1 stop Lima J Chavez Intl

4:50 pm - 1:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 05m1 stop Lima J Chavez Intl

$541Multiple Airlines

Wed, Apr 14 - Mon, Apr 19

6:46 am - 12:21 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 35m1 stop Guayaquil Jose Joaquin de Olmedo

7:05 pm - 1:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

8h 50m1 stop Lima J Chavez Intl

$564LATAM Airlines

Thu, Mar 11 - Mon, Mar 15

12:35 pm - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 10m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

2:10 am - 2:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

14h 00m1 stop Bogotá El Dorado

$589Avianca

Fri, Nov 6 - Thu, Nov 12

8:35 pm - 3:10 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

16h 35m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

4:15 pm - 11:55 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

9h 40m1 stop Bogotá El Dorado

$589Avianca

Tue, Nov 24 - Thu, Nov 26

6:36 pm - 12:24 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

27h 48m1 stop Panama City Tocumen Intl

3:48 am - 12:34 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 46m1 stop Panama City Tocumen Intl

$644Copa Airlines

Sat, Nov 14 - Fri, Nov 20

6:36 pm - 5:52 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

9h 16m1 stop Panama City Tocumen Intl

5:07 am - 11:34 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

20h 27m1 stop Panama City Tocumen Intl

$654Copa Airlines

Mon, Nov 30 - Thu, Dec 24

Cheap last minute flights

Enter your travel dates to find the best prices.

6:30 am - 12:20 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 50m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

4:15 pm - 11:55 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

9h 40m1 stop Bogotá El Dorado

$589Avianca

Sat, Oct 24 - Sat, Oct 31

10:25 am - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

2:10 am - 2:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

14h 00m1 stop Bogotá El Dorado

$589Avianca

Fri, Oct 23 - Thu, Oct 29

4:48 pm - 4:33 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

9h 45m1 stop Lima J Chavez Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$596JetSMART

Mon, Oct 26 - Mon, Nov 2

6:32 pm - 12:22 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

27h 50m1 stop Panama City Tocumen Intl

3:28 am - 12:30 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 02m1 stop Panama City Tocumen Intl

$602Copa Airlines

Thu, Oct 22 - Wed, Oct 28

12:27 pm - 12:22 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

9h 55m1 stop Panama City Tocumen Intl

3:48 am - 12:34 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 46m1 stop Panama City Tocumen Intl

$602Copa Airlines

Fri, Oct 23 - Thu, Nov 12

1:40 pm - 8:19 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

28h 39m2 stops Guayaquil Jose Joaquin de Olmedo Panama City Tocumen Intl

6:07 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 57m1 stop Lima J Chavez Intl

$611Multiple Airlines

Mon, Oct 26 - Wed, Oct 28

1:40 pm - 8:19 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

28h 39m2 stops Guayaquil Jose Joaquin de Olmedo Panama City Tocumen Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$614Multiple Airlines

Tue, Oct 27 - Sun, Nov 1

4:48 pm - 5:03 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 15m1 stop Lima J Chavez Intl

6:07 am - 4:05 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 58m1 stop Lima J Chavez Intl

$646JetSMART

Fri, Oct 23 - Sun, Nov 8

3:25 pm - 11:41 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

18h 16m3 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl Buenos Aires Jorge Newbery

7:05 pm - 5:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 50m2 stops Lima J Chavez Intl Guayaquil Jose Joaquin de Olmedo

$1,095LATAM Airlines

Mon, Oct 26 - Mon, Nov 2

3:25 pm - 11:41 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

18h 16m3 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl Buenos Aires Jorge Newbery

8:25 pm - 6:47 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 22m2 stops Lima J Chavez Intl Guayaquil Jose Joaquin de Olmedo

$1,114LATAM Airlines

Mon, Oct 26 - Mon, Nov 2

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LATAM Airlines flights from Quito to Santiago

Our best LATAM Airlines deals on Quito to Santiago flight tickets

LATAM Airlines

Mar 15

UIO11:00 amQuito Mariscal Sucr

11h 21m

1 stop

SCL12:21 amSantiago Arturo Merino Benitez

Mar 22

SCL5:55 pmSantiago Arturo Merino Benitez

10h 00m

1 stop

UIO1:55 amQuito Mariscal Sucr

$443

LATAM Airlines

Nov 3

UIO6:20 amQuito Mariscal Sucr

16h 01m

1 stop

SCL12:21 amSantiago Arturo Merino Benitez

Nov 6

SCL8:13 amSantiago Arturo Merino Benitez

16h 47m

1 stop

UIO11:00 pmQuito Mariscal Sucr

$564

LATAM Airlines

Nov 3

UIO7:50 pmQuito Mariscal Sucr

7h 30m

1 stop

SCL5:20 amSantiago Arturo Merino Benitez

Nov 6

SCL8:13 amSantiago Arturo Merino Benitez

16h 47m

1 stop

UIO11:00 pmQuito Mariscal Sucr

$574

JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets

JetSMART

Dec 2

UIO4:50 pmQuito Mariscal Sucr

10h 15m

1 stop

SCL5:05 amSantiago Arturo Merino Benitez

Dec 6

SCL6:07 amSantiago Arturo Merino Benitez

11h 58m

1 stop

UIO4:05 pmQuito Mariscal Sucr

$455

JetSMART

Nov 27

UIO4:50 pmQuito Mariscal Sucr

10h 15m

1 stop

SCL5:05 amSantiago Arturo Merino Benitez

Dec 2

SCL6:07 amSantiago Arturo Merino Benitez

11h 58m

1 stop

UIO4:05 pmQuito Mariscal Sucr

$471

JetSMART

Mar 10

UIO4:50 pmQuito Mariscal Sucr

16h 03m

1 stop

SCL10:53 amSantiago Arturo Merino Benitez

Mar 16

SCL12:32 pmSantiago Arturo Merino Benitez

29h 32m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$474

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Mon 3/15

11:00 am-12:21 am

1 stop11h 21m

Santiago Arturo Merino Benitez

Mon 3/22

5:55 pm-1:55 am

1 stop10h 00m

$443

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 12/2

4:50 pm-5:05 am

1 stop10h 15m

Santiago Arturo Merino Benitez

Sun 12/6

6:07 am-4:05 pm

1 stop11h 58m

$455

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 11/27

4:50 pm-5:05 am

1 stop10h 15m

Santiago Arturo Merino Benitez

Wed 12/2

6:07 am-4:05 pm

1 stop11h 58m

$471

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 3/10

4:50 pm-10:53 am

1 stop16h 03m

Santiago Arturo Merino Benitez

Tue 3/16

7:00 pm-9:45 pm

Nonstop4h 45m

$520

Quickest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 4/14

4:49 pm-4:16 am

1 stop10h 27m

Santiago Arturo Merino Benitez

Mon 4/19

4:50 pm-1:55 am

1 stop10h 05m

$541

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Thu 3/11

6:46 am-12:21 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Mon 3/15

7:05 pm-1:55 am

1 stop8h 50m

$564

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 11/6

12:35 pm-5:45 am

2 stops15h 10m

Santiago Arturo Merino Benitez

Thu 11/12

2:10 am-2:10 pm

1 stop14h 00m

$589

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Tue 11/24

8:35 pm-3:10 pm

2 stops16h 35m

Santiago Arturo Merino Benitez

Thu 11/26

4:15 pm-11:55 pm

1 stop9h 40m

$589

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sat 11/14

6:36 pm-12:24 am

1 stop27h 48m

Santiago Arturo Merino Benitez

Fri 11/20

3:48 am-12:34 pm

1 stop10h 46m

$644

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Mon 11/30

6:36 pm-5:52 am

1 stop9h 16m

Santiago Arturo Merino Benitez

Thu 12/24

5:07 am-11:34 pm

1 stop20h 27m

$654

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Quito and Santiago?

Prices are currently typical for flights on this route.

Typical prices usually range from $272 to $524.
The lowest price recently found on this route was $455.

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $363. If you don’t want to visit Santiago in June, then you should wait until April to fly from Quito, when ticket prices are also cheap, with an average price of $363.

What is the cheapest Quito Mariscal Sucr to Santiago Arturo Merino Benitez flight route?

Fly from Quito Mariscal Sucr to Santiago Arturo Merino Benitez for the best Quito Mariscal Sucr - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight from Quito to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $408 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $364 on momondo.

What cabin class options are available on Quito to Santiago flights?

There is only 1 cabin class available to choose from on Quito to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 18% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of October 2026, prices for Quito to Santiago flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Best Price Found	$263
Fastest flight time	5h 00m
Direct flights	Mon, Wed, Fri and Sun
Airports in Santiago	1 airport

The best one-way flight to Santiago from Quito in the past 72 hours is $263. The best round-trip flight deal from Quito to Santiago found on momondo in the last 72 hours is $443.

The fastest flight from Quito to Santiago takes 5h 00m

Direct flights go from Quito to Santiago on Monday, Wednesday, Friday and Sunday. The only airline offering direct flights is LATAM Airlines.

There is 1 airport in Santiago. From Quito there are direct flights to Santiago Arturo Merino Benitez (SCL).

Search flight deals

Frequently asked questions about flying from Quito to Santiago

How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 5h 00m.
When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of October 2026.
How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Quito to Santiago?
Based on momondo bookings for flights between Quito and Santiago, the leading plane model is Airbus A320-100/200, making up 100.00% of the total bookings.
What is the most popular airline from Quito to Santiago?
momondo data reveals that the most frequently booked airline on the route from Quito to Santiago is LATAM Airlines, representing 47% of all bookings. The subsequent popular airlines are JetSMART at 31%, Avianca at 14%, and Copa Airlines at 9%.

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo

Airline	Rating	Free Cancellation	Price
JetSMART	PriceFrom $198	Free Cancellation	Rating 6.8 348 reviews	Search JetSMART flights
LATAM Airlines	PriceFrom $221	Free Cancellation	Rating 7.4 1,971 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $275	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights
Avianca	PriceFrom $286	Free Cancellation	Rating 6.5 2,552 reviews	Search Avianca flights

Viña del Mar

Valparaíso

Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.