Which layover airport has the shortest travel time from Quito to Santiago?

Flights connecting via Guayaquil (GYE) have the shortest average one-way travel time: 6h 53m.

Which airport is the most popular layover for flights between Quito and Santiago?

Lima (LIM) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Quito to Santiago?

Flights via Lima (LIM) offer the lowest average round-trip price of $459.

What is the cheapest airline that flies from Quito Mariscal Sucr to Santiago Arturo Merino Benitez?

LATAM Airlines and JetSMART are the most popular carriers operating from Quito Mariscal Sucr to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

LATAM Airlines, JetSMART and Avianca are the top three most popular airlines that fly to Santiago from Quito according to our data. LATAM Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Quito to Santiago?

Panama City (PTY) has the shortest average layover time for this route: 0h 50m.

When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of August 2026.

How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$223 Cheap Flights from Quito to Santiago in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Quito to Santiago

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:01 pm - 3:00 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

19h 59m2 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl

8:25 pm - 11:00 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

28h 35m2 stops Lima J Chavez Intl Bogotá El Dorado

$404LATAM Airlines

Wed, Oct 28 - Wed, Nov 18

7:45 am - 12:29 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

14h 44m1 stop Guayaquil Jose Joaquin de Olmedo

8:25 pm - 1:55 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

7h 30m1 stop Lima J Chavez Intl

$404LATAM Airlines

Fri, Oct 23 - Sun, Nov 1

4:50 pm - 5:03 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 13m1 stop Lima J Chavez Intl

6:07 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

11h 57m1 stop Lima J Chavez Intl

$436JetSMART

Fri, Nov 6 - Fri, Nov 13

4:48 pm - 4:13 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 25m1 stop Lima J Chavez Intl

5:47 am - 4:03 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 16m1 stop Lima J Chavez Intl

$440JetSMART

Wed, Sep 2 - Wed, Sep 9

4:50 pm - 5:03 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 13m1 stop Lima J Chavez Intl

1:30 pm - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

28h 34m1 stop Lima J Chavez Intl

$462Multiple Airlines

Fri, Nov 27 - Thu, Dec 3

8:47 pm - 4:45 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

18h 58m2 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl

5:47 am - 4:03 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 16m1 stop Lima J Chavez Intl

$472Multiple Airlines

Wed, Sep 2 - Wed, Sep 9

10:25 am - 5:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

4:25 pm - 1:20 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 55m1 stop Bogotá El Dorado

$541Avianca

Fri, Oct 23 - Sun, Nov 1

6:30 am - 12:20 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

15h 50m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

4:25 pm - 11:50 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

9h 25m1 stop Bogotá El Dorado

$541Avianca

Sat, Oct 24 - Sat, Oct 31

12:27 pm - 3:56 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 29m1 stop Panama City Tocumen Intl

3:57 am - 12:30 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 33m1 stop Panama City Tocumen Intl

$554Copa Airlines

Wed, Oct 14 - Tue, Oct 20

12:27 pm - 3:56 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 29m1 stop Panama City Tocumen Intl

3:57 am - 12:30 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 33m1 stop Panama City Tocumen Intl

$554Copa Airlines

Wed, Oct 14 - Tue, Oct 20

Cheap last minute flights

Enter your travel dates to find the best prices.

4:49 pm - 4:06 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 17m1 stop Lima J Chavez Intl

4:46 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 18m1 stop Lima J Chavez Intl

$504JetSMART

Wed, Aug 19 - Wed, Aug 26

2:15 pm - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 30m1 stop Bogotá El Dorado

4:20 pm - 1:15 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

10h 55m1 stop Bogotá El Dorado

$551Avianca

Thu, Aug 20 - Thu, Sep 17

2:15 pm - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 30m1 stop Bogotá El Dorado

4:46 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 18m1 stop Lima J Chavez Intl

$556Multiple Airlines

Fri, Aug 21 - Mon, Aug 24

2:15 pm - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 30m1 stop Bogotá El Dorado

4:46 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 18m1 stop Lima J Chavez Intl

$556Multiple Airlines

Thu, Aug 20 - Mon, Aug 24

10:25 am - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado

12:30 am - 1:10 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

13h 40m2 stops Bogotá El Dorado Guayaquil Jose Joaquin de Olmedo

$560Avianca

Fri, Aug 21 - Sun, Aug 23

2:15 pm - 4:45 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

13h 30m1 stop Bogotá El Dorado

6:40 am - 7:35 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

13h 55m2 stops Bogotá El Dorado Guayaquil Jose Joaquin de Olmedo

$570Avianca

Thu, Aug 20 - Mon, Aug 24

6:30 pm - 10:43 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

27h 13m1 stop Panama City Tocumen Intl

12:43 am - 12:31 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 48m1 stop Panama City Tocumen Intl

$582Copa Airlines

Tue, Aug 18 - Sun, Aug 23

4:49 pm - 4:06 amUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 17m1 stop Lima J Chavez Intl

4:56 am - 4:04 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

12h 08m1 stop Lima J Chavez Intl

$619JetSMART

Fri, Aug 21 - Fri, Aug 28

6:00 am - 4:45 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

9h 45m2 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl

8:50 am - 11:00 pmSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

16h 10m2 stops Lima J Chavez Intl Bogotá El Dorado

$622LATAM Airlines

Thu, Aug 20 - Thu, Sep 17

6:00 am - 5:25 pmUIO Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez

10h 25m2 stops Guayaquil Jose Joaquin de Olmedo Lima J Chavez Intl

6:45 pm - 11:40 amSCL Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr

17h 55m2 stops Lima J Chavez Intl Bogotá El Dorado

$622LATAM Airlines

Thu, Aug 20 - Mon, Aug 24

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LATAM Airlines flights from Quito to Santiago

Our best LATAM Airlines deals on Quito to Santiago flight tickets

LATAM Airlines

Oct 23

UIO6:00 amQuito Mariscal Sucr

14h 55m

2 stops

SCL10:55 pmSantiago Arturo Merino Benitez

Nov 1

SCL8:25 pmSantiago Arturo Merino Benitez

7h 30m

1 stop

UIO1:55 amQuito Mariscal Sucr

$404

LATAM Airlines

Oct 21

UIO8:05 pmQuito Mariscal Sucr

8h 20m

1 stop

SCL6:25 amSantiago Arturo Merino Benitez

Jan 14

SCL7:00 pmSantiago Arturo Merino Benitez

4h 45m

UIO9:45 pmQuito Mariscal Sucr

$415

LATAM Airlines

Oct 23

UIO6:00 amQuito Mariscal Sucr

14h 55m

2 stops

SCL10:55 pmSantiago Arturo Merino Benitez

Nov 1

SCL8:25 pmSantiago Arturo Merino Benitez

15h 04m

2 stops

UIO9:29 amQuito Mariscal Sucr

$423

JetSMART flights from Quito to Santiago

Our best JetSMART deals on Quito to Santiago flight tickets

JetSMART

Nov 6

UIO4:50 pmQuito Mariscal Sucr

10h 13m

1 stop

SCL5:03 amSantiago Arturo Merino Benitez

Nov 13

SCL6:07 amSantiago Arturo Merino Benitez

11h 57m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$436

JetSMART

Sep 2

UIO4:48 pmQuito Mariscal Sucr

10h 25m

1 stop

SCL4:13 amSantiago Arturo Merino Benitez

Sep 9

SCL5:47 amSantiago Arturo Merino Benitez

12h 16m

1 stop

UIO4:03 pmQuito Mariscal Sucr

$440

JetSMART

Oct 23

UIO4:48 pmQuito Mariscal Sucr

10h 20m

1 stop

SCL5:08 amSantiago Arturo Merino Benitez

Nov 1

SCL6:07 amSantiago Arturo Merino Benitez

11h 57m

1 stop

UIO4:04 pmQuito Mariscal Sucr

$442

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 10/28

5:01 pm-3:00 pm

2 stops19h 59m

Santiago Arturo Merino Benitez

Wed 11/18

8:25 pm-11:00 pm

2 stops28h 35m

$404

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 10/23

7:45 am-12:29 am

1 stop14h 44m

Santiago Arturo Merino Benitez

Sun 11/1

8:25 pm-1:55 am

1 stop7h 30m

$404

Quickest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 11/6

4:50 pm-5:03 am

1 stop10h 13m

Santiago Arturo Merino Benitez

Fri 11/13

6:07 am-4:04 pm

1 stop11h 57m

$436

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 9/2

4:48 pm-4:13 am

1 stop10h 25m

Santiago Arturo Merino Benitez

Wed 9/9

5:47 am-4:03 pm

1 stop12h 16m

$440

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 11/27

4:50 pm-5:03 am

1 stop10h 13m

Santiago Arturo Merino Benitez

Thu 12/3

1:30 pm-4:04 pm

1 stop28h 34m

$462

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 9/2

8:47 pm-4:45 pm

2 stops18h 58m

Santiago Arturo Merino Benitez

Wed 9/9

5:47 am-4:03 pm

1 stop12h 16m

$472

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 10/23

10:25 am-5:45 am

2 stops17h 20m

Santiago Arturo Merino Benitez

Sun 11/1

4:25 pm-1:20 am

1 stop10h 55m

$541

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sat 10/24

6:30 am-12:20 am

2 stops15h 50m

Santiago Arturo Merino Benitez

Sat 10/31

4:25 pm-11:50 pm

1 stop9h 25m

$541

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 10/14

12:27 pm-3:56 am

1 stop13h 29m

Santiago Arturo Merino Benitez

Tue 10/20

3:57 am-12:30 pm

1 stop10h 33m

$554

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 10/14

12:27 pm-3:56 am

1 stop13h 29m

Santiago Arturo Merino Benitez

Tue 10/20

3:57 am-12:30 pm

1 stop10h 33m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Quito to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Quito and Santiago?

Prices are currently typical for flights on this route.

Typical prices usually range from $253 to $531.
The lowest price recently found on this route was $404.

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Quito to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $361. If you don’t want to visit Santiago in June, then you should wait until April to fly from Quito, when ticket prices are also cheap, with an average price of $363.

What is the cheapest Quito Mariscal Sucr to Santiago Arturo Merino Benitez flight route?

Fly from Quito Mariscal Sucr to Santiago Arturo Merino Benitez for the best Quito Mariscal Sucr - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight from Quito to Santiago?

You are more likely to see cheaper flights to Santiago from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $412 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Quito for as low as $355 on momondo.

What cabin class options are available on Quito to Santiago flights?

There is only 1 cabin class available to choose from on Quito to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Quito to Santiago flights?

You could potentially save up to 1% on your flight if you consider stops on a Quito to Santiago flight.

How have Quito to Santiago flight prices changed over time?

As of August 2026, prices for Quito to Santiago flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Quito to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Quito to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Quito to Santiago (UIO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Quito to Santiago

Best Price Found	$223
Fastest flight time	5h 00m
Direct flights	Mon, Wed and Sun
Airports in Santiago	1 airport

The best one-way flight to Santiago from Quito in the past 72 hours is $223. The best round-trip flight deal from Quito to Santiago found on momondo in the last 72 hours is $404.

The fastest flight from Quito to Santiago takes 5h 00m

Direct flights go from Quito to Santiago on Monday, Wednesday and Sunday. There are no airlines offering direct flights.

There is 1 airport in Santiago. From Quito there are direct flights to Santiago Arturo Merino Benitez (SCL).

Search flight deals

Frequently asked questions about flying from Quito to Santiago

How far is Quito Mariscal Sucr to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Quito Mariscal Sucr to Santiago Arturo Merino Benitez is 2349.7 mi. A reasonable flight in good conditions will take 5h 00m.
When did momondo last update prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport is 4 as of August 2026.
How old do you have to be to fly from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Quito to Santiago?
Based on momondo bookings for flights between Quito and Santiago, the leading plane model is Airbus A320-100/200, making up 100.00% of the total bookings.
What is the most popular airline from Quito to Santiago?
momondo data reveals that the most frequently booked airline on the route from Quito to Santiago is LATAM Airlines, representing 52% of all bookings. The subsequent popular airlines are JetSMART at 27%, Avianca at 12%, and Copa Airlines at 9%.

Best airlines flying from Quito to Santiago

Compare and see reviews for airlines that fly from Quito to Santiago with momondo

Airline	Rating	Free Cancellation	Price
JetSMART	PriceFrom $193	Free Cancellation	Rating 6.8 337 reviews	Search JetSMART flights
Avianca	PriceFrom $232	Free Cancellation	Rating 6.5 2,540 reviews	Search Avianca flights
Copa Airlines	PriceFrom $275	Free Cancellation	Rating 7.6 1,557 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $303	Free Cancellation	Rating 7.4 1,986 reviews	Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Quito to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Quito to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Quito to Santiago with flexible booking policies on momondo?

Flights from Quito to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Quito to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Quito. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Quito to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Quito to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.