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Cheap flights from Portland to Santo Domingo from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santo Domingo departing on 5/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:35 pm - 9:53 am
PDX
-
SDQ
18h 18m
2 stops
Frontier Logo
10:58 am - 10:20 am
SDQ
-
PDX
26h 22m
2 stops
$544Frontier
Sat, May 23 - Thu, May 28
Frontier Logo
12:35 pm - 9:53 am
PDX
-
SDQ
18h 18m
2 stops
Frontier Logo
10:58 am - 10:20 am
SDQ
-
PDX
26h 22m
2 stops
$555Frontier
Sat, May 23 - Thu, May 28
Delta Logo
1:05 pm - 1:12 pm
PDX
-
SDQ
21h 07m
2 stops
Delta Logo
2:49 pm - 8:37 am
SDQ
-
PDX
20h 48m
2 stops
$621Delta
Thu, Apr 30 - Wed, May 13
Multiple Airlines Logo
9:46 pm - 2:35 am
PDX
-
SDQ
25h 49m
1 stop
Multiple Airlines Logo
6:30 am - 9:11 am
SDQ
-
PDX
29h 41m
1 stop
$622Multiple Airlines
Sat, May 23 - Fri, May 29
JetBlue Logo
2:30 pm - 1:44 am
PDX
-
SDQ
32h 14m
1 stop
JetBlue Logo
3:10 am - 1:10 pm
SDQ
-
PDX
13h 00m
1 stop
$626JetBlue
Thu, May 28 - Mon, Jun 1
Delta Logo
11:03 pm - 6:01 pm
PDX
-
SDQ
15h 58m
1 stop
Delta Logo
7:35 pm - 11:46 am
SDQ
-
PDX
19h 11m
1 stop
$628Delta
Sat, May 23 - Thu, May 28
Delta Logo
11:12 pm - 6:01 pm
PDX
-
SDQ
15h 49m
2 stops
Delta Logo
6:05 am - 9:46 pm
SDQ
-
PDX
18h 41m
2 stops
$633Delta
Sat, May 23 - Fri, May 29
Delta Logo
11:03 pm - 12:28 pm
PDX
-
SDQ
10h 25m
1 stop
Delta Logo
6:05 am - 9:00 pm
SDQ
-
PDX
17h 55m
1 stop
$648Delta
Sat, May 23 - Sat, May 30
Delta Logo
11:12 pm - 6:01 pm
PDX
-
SDQ
15h 49m
2 stops
Delta Logo
6:05 am - 9:46 pm
SDQ
-
PDX
18h 41m
2 stops
$653Delta
Sat, May 23 - Fri, May 29
JetBlue Logo
2:30 pm - 1:44 am
PDX
-
SDQ
32h 14m
1 stop
JetBlue Logo
3:10 am - 1:10 pm
SDQ
-
PDX
13h 00m
1 stop
$655JetBlue
Fri, May 22 - Fri, May 29

Frontier flights from Portland to Santo Domingo

Our best Frontier deals on Portland to Santo Domingo flight tickets
Frontier
May 23
PDX12:35 pmPortland
18h 18m
2 stops
SDQ9:53 amSanto Domingo Las Americas
May 28
SDQ10:58 amSanto Domingo Las Americas
26h 22m
2 stops
PDX10:20 amPortland
$544
Frontier
May 23
PDX12:35 pmPortland
18h 18m
2 stops
SDQ9:53 amSanto Domingo Las Americas
May 28
SDQ10:58 amSanto Domingo Las Americas
26h 22m
2 stops
PDX10:20 amPortland
$555
Frontier
Apr 9
PDX5:19 pmPortland
18h 34m
2 stops
SDQ2:53 pmSanto Domingo Las Americas
Apr 13
SDQ3:01 pmSanto Domingo Las Americas
25h 01m
2 stops
PDX1:02 pmPortland
$815

Delta flights from Portland to Santo Domingo

Our best Delta deals on Portland to Santo Domingo flight tickets
Delta
Apr 30
PDX1:05 pmPortland
21h 07m
2 stops
SDQ1:12 pmSanto Domingo Las Americas
May 13
SDQ2:49 pmSanto Domingo Las Americas
20h 48m
2 stops
PDX8:37 amPortland
$621
Delta
May 23
PDX11:03 pmPortland
15h 58m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
May 28
SDQ7:35 pmSanto Domingo Las Americas
19h 11m
1 stop
PDX11:46 amPortland
$628
Delta
May 23
PDX11:12 pmPortland
15h 49m
2 stops
SDQ6:01 pmSanto Domingo Las Americas
May 29
SDQ6:05 amSanto Domingo Las Americas
18h 41m
2 stops
PDX9:46 pmPortland
$633

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

12:35 pm-9:53 am

2 stops18h 18m

Santo Domingo Las Americas

Thu 5/28

10:58 am-10:20 am

2 stops26h 22m

$544

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

12:35 pm-9:53 am

2 stops18h 18m

Santo Domingo Las Americas

Thu 5/28

10:58 am-10:20 am

2 stops26h 22m

$555

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Thu 4/30

1:05 pm-1:12 pm

2 stops21h 07m

Santo Domingo Las Americas

Wed 5/13

2:49 pm-8:37 am

2 stops20h 48m

$621

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

9:46 pm-2:35 am

1 stop25h 49m

Santo Domingo Las Americas

Fri 5/29

6:30 am-9:11 am

1 stop29h 41m

$622

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Thu 5/28

2:30 pm-1:44 am

1 stop32h 14m

Santo Domingo Las Americas

Mon 6/1

3:10 am-1:10 pm

1 stop13h 00m

$626

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

11:03 pm-6:01 pm

1 stop15h 58m

Santo Domingo Las Americas

Thu 5/28

7:35 pm-11:46 am

1 stop19h 11m

$628

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

11:12 pm-6:01 pm

2 stops15h 49m

Santo Domingo Las Americas

Fri 5/29

6:05 am-9:46 pm

2 stops18h 41m

$633
Quickest round-trip

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

11:03 pm-12:28 pm

1 stop10h 25m

Santo Domingo Las Americas

Sat 5/30

6:05 am-9:00 pm

1 stop17h 55m

$648

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 5/23

11:12 pm-6:01 pm

2 stops15h 49m

Santo Domingo Las Americas

Fri 5/29

6:05 am-9:46 pm

2 stops18h 41m

$653

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Fri 5/22

2:30 pm-1:44 am

1 stop32h 14m

Santo Domingo Las Americas

Fri 5/29

3:10 am-1:10 pm

1 stop13h 00m

$655

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Portland to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until November to fly from Portland, when ticket prices are also cheap, with an average price of $578.

Can stopping save me money on Portland to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a Portland to Santo Domingo flight.

When to book flights from Portland to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santo Domingo (PDX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santo Domingo

Fastest flight time

11h 15m

Direct flights

None
The fastest flight from Portland to Santo Domingo takes 11h 15m
There are no direct flights from Portland to Santo Domingo. There are no popular flight routes from Portland to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Portland to Santo Domingo

  • How far is Portland to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3525.7 mi away from Portland. 11h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Portland Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Portland Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Portland Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Portland to Santo Domingo?

Best airlines flying from Portland to Santo Domingo

Compare and see reviews for airlines that fly from Portland to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $532Free CancellationRating
7.9
8,392 reviews
Search Delta flights
American AirlinesPriceFrom $536Free CancellationRating
7.1
11,560 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santo Domingo for you.

Can I find flights from Portland to Santo Domingo with flexible booking policies on momondo?

All flight searches from Portland to Santo Domingo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Santo Domingo?

momondo helps you find the best flight between Portland and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Portland to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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