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Cheap flights from Portland to Santo Domingo from $256

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santo Domingo departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:45 pm - 3:58 pmPDX-SDQ
13h 13m1 stop
American Airlines Logo
3:16 pm - 12:59 amSDQ-PDX
13h 43m1 stop
$536American Airlines
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Fri, Dec 5 - Mon, Dec 22
Delta Logo
5:30 pm - 2:21 pmPDX-SDQ
16h 51m2 stops
Delta Logo
7:31 am - 10:15 pmSDQ-PDX
18h 44m2 stops
$540Delta
Find Deal
Thu, Jan 22 - Mon, Jan 26
Delta Logo
7:00 am - 11:59 pmPDX-SDQ
12h 59m1 stop
Delta Logo
7:05 am - 8:27 pmSDQ-PDX
17h 22m1 stop
$577Delta
Find Deal
Sat, Feb 28 - Sat, Mar 7
Delta Logo
12:40 am - 12:32 amPDX-SDQ
19h 52m2 stops
Delta Logo
7:31 am - 8:27 pmSDQ-PDX
16h 56m1 stop
$581Delta
Find Deal
Wed, Jan 21 - Mon, Jan 26
American Airlines Logo
10:15 pm - 5:29 pmPDX-SDQ
15h 14m2 stops
American Airlines Logo
6:00 am - 10:11 pmSDQ-PDX
20h 11m2 stops
$586American Airlines
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Sun, Jan 11 - Sun, Jan 18
Multiple Airlines Logo
7:00 am - 9:45 pmPDX-SDQ
10h 45m1 stop
Multiple Airlines Logo
2:57 pm - 9:29 amSDQ-PDX
22h 32m2 stops
$591Multiple Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 12
Multiple Airlines Logo
7:00 am - 9:45 pmPDX-SDQ
10h 45m1 stop
Multiple Airlines Logo
2:57 pm - 8:27 pmSDQ-PDX
33h 30m1 stop
$598Multiple Airlines
Find Deal
Thu, Jan 8 - Mon, Jan 12
American Airlines Logo
11:01 pm - 1:57 pmPDX-SDQ
10h 56m1 stop
American Airlines Logo
6:00 am - 11:46 pmSDQ-PDX
21h 46m1 stop
$599American Airlines
Find Deal
Sun, Jan 11 - Sun, Jan 18
American Airlines Logo
10:15 pm - 5:23 pmPDX-SDQ
15h 08m2 stops
American Airlines Logo
4:49 pm - 12:59 amSDQ-PDX
12h 10m1 stop
$607American Airlines
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Fri, Dec 5 - Mon, Dec 22
Delta Logo
12:40 am - 11:59 pmPDX-SDQ
19h 19m2 stops
Delta Logo
7:05 am - 8:27 pmSDQ-PDX
17h 22m1 stop
$622Delta
Find Deal
Fri, Feb 27 - Sat, Mar 7

Delta flights from Portland to Santo Domingo

Our best Delta deals on Portland to Santo Domingo flight tickets
Delta
Jan 22
PDX7:00 amPortland
13h 32m
1 stop
SDQ12:32 amSanto Domingo Las Americas
Jan 26
SDQ7:31 amSanto Domingo Las Americas
18h 44m
2 stops
PDX10:15 pmPortland
$540
Find similar
Delta
Feb 28
PDX7:00 amPortland
12h 59m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
Mar 7
SDQ7:05 amSanto Domingo Las Americas
17h 22m
1 stop
PDX8:27 pmPortland
$577
Find similar
Delta
Jan 21
PDX12:40 amPortland
14h 34m
2 stops
SDQ7:14 pmSanto Domingo Las Americas
Jan 26
SDQ7:31 amSanto Domingo Las Americas
16h 56m
1 stop
PDX8:27 pmPortland
$581
Find similar

American Airlines flights from Portland to Santo Domingo

Our best American Airlines deals on Portland to Santo Domingo flight tickets
American Airlines
Dec 5
PDX10:45 pmPortland
13h 13m
1 stop
SDQ3:58 pmSanto Domingo Las Americas
Dec 22
SDQ3:16 pmSanto Domingo Las Americas
13h 43m
1 stop
PDX12:59 amPortland
$536
Find similar
American Airlines
Jan 11
PDX11:01 pmPortland
14h 28m
1 stop
SDQ5:29 pmSanto Domingo Las Americas
Jan 18
SDQ6:00 amSanto Domingo Las Americas
20h 11m
2 stops
PDX10:11 pmPortland
$586
Find similar
American Airlines
Jan 11
PDX11:01 pmPortland
10h 56m
1 stop
SDQ1:57 pmSanto Domingo Las Americas
Jan 18
SDQ6:00 amSanto Domingo Las Americas
21h 46m
1 stop
PDX11:46 pmPortland
$599
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Fri 12/5

10:45 pm-3:58 pm

1 stop13h 13m

Santo Domingo Las Americas

Mon 12/22

3:16 pm-12:59 am

1 stop13h 43m

$536

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Thu 1/22

5:30 pm-2:21 pm

2 stops16h 51m

Santo Domingo Las Americas

Mon 1/26

7:31 am-10:15 pm

2 stops18h 44m

$540

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sat 2/28

7:00 am-11:59 pm

1 stop12h 59m

Santo Domingo Las Americas

Sat 3/7

7:05 am-8:27 pm

1 stop17h 22m

$577

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Wed 1/21

12:40 am-12:32 am

2 stops19h 52m

Santo Domingo Las Americas

Mon 1/26

7:31 am-8:27 pm

1 stop16h 56m

$581

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sun 1/11

10:15 pm-5:29 pm

2 stops15h 14m

Santo Domingo Las Americas

Sun 1/18

6:00 am-10:11 pm

2 stops20h 11m

$586

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Thu 1/8

7:00 am-9:45 pm

1 stop10h 45m

Santo Domingo Las Americas

Mon 1/12

2:57 pm-9:29 am

2 stops22h 32m

$591

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Thu 1/8

7:00 am-9:45 pm

1 stop10h 45m

Santo Domingo Las Americas

Mon 1/12

2:57 pm-8:27 pm

1 stop33h 30m

$598

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Sun 1/11

11:01 pm-1:57 pm

1 stop10h 56m

Santo Domingo Las Americas

Sun 1/18

6:00 am-11:46 pm

1 stop21h 46m

$599

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Fri 12/5

10:15 pm-5:23 pm

2 stops15h 08m

Santo Domingo Las Americas

Mon 12/22

4:49 pm-12:59 am

1 stop12h 10m

$607

PortlandSanto Domingo

PDX - SDQ

PDXSDQ

Portland

Fri 2/27

12:40 am-11:59 pm

2 stops19h 19m

Santo Domingo Las Americas

Sat 3/7

7:05 am-8:27 pm

1 stop17h 22m

$622

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Portland to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until November to fly from Portland, when ticket prices are also cheap, with an average price of $608.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $609. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $965.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $680. Try not to purchase tickets in the afternoon because they tend to be around $857. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Portland to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a Portland to Santo Domingo flight.

When to book flights from Portland to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santo Domingo (PDX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santo Domingo

Direct flights

None
There are no direct flights from Portland to Santo Domingo. There are no popular flight routes from Portland to Santo Domingo.
Search flight deals

  • How far is Portland to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3525.7 mi away from Portland. 9h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Portland Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Portland Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Portland Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Portland to Santo Domingo?

Best airlines flying from Portland to Santo Domingo

Compare and see reviews for airlines that fly from Portland to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $532Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $537Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
American AirlinesPriceFrom $563Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santo Domingo for you.

Can I find flights from Portland to Santo Domingo with flexible booking policies on momondo?

All flight searches from Portland to Santo Domingo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Santo Domingo?

momondo helps you find the best flight between Portland and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Portland to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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