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Cheap flights from Portland to Santiago from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 11/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:50 pm - 5:35 amPDX-SCL
30h 45m1 stop
Multiple Airlines Logo
3:30 pm - 8:30 pmSCL-PDX
33h 00m2 stops
$834Multiple Airlines
Find Deal
Sat, Jan 24 - Tue, Mar 31
Multiple Airlines Logo
1:21 pm - 6:30 amPDX-SCL
36h 09m1 stop
Multiple Airlines Logo
9:05 pm - 8:44 pmSCL-PDX
28h 39m2 stops
$854Multiple Airlines
Find Deal
Thu, Nov 13 - Tue, Nov 25
Air Canada Logo
9:50 am - 12:15 pmPDX-SCL
21h 25m2 stops
Air Canada Logo
8:55 pm - 6:30 pmSCL-PDX
26h 35m2 stops
$875Air Canada
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Mon, Feb 2 - Thu, Feb 12
LATAM Airlines Logo
7:00 am - 6:55 amPDX-SCL
18h 55m1 stop
LATAM Airlines Logo
11:55 pm - 11:53 amSCL-PDX
15h 58m1 stop
$912LATAM Airlines
Find Deal
Thu, Jan 22 - Mon, Mar 23
LATAM Airlines Logo
7:05 am - 6:55 amPDX-SCL
18h 50m1 stop
LATAM Airlines Logo
11:35 pm - 11:46 amSCL-PDX
17h 11m1 stop
$913LATAM Airlines
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Thu, Nov 13 - Tue, Nov 25
Air Canada Logo
3:15 pm - 7:00 amPDX-SCL
58h 45m2 stops
Air Canada Logo
7:55 pm - 6:30 pmSCL-PDX
26h 35m2 stops
$919Air Canada
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Tue, Mar 3 - Tue, Mar 17
United Airlines Logo
1:15 pm - 8:50 amPDX-SCL
14h 35m1 stop
United Airlines Logo
10:45 pm - 9:26 pmSCL-PDX
27h 41m2 stops
$946United Airlines
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Thu, Nov 13 - Tue, Nov 25
United Airlines Logo
6:00 am - 8:50 amPDX-SCL
21h 50m3 stops
United Airlines Logo
10:45 pm - 1:47 pmSCL-PDX
20h 02m2 stops
$948United Airlines
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Thu, Nov 13 - Tue, Nov 25
Delta Logo
11:59 am - 2:05 pmPDX-SCL
21h 06m2 stops
Delta Logo
12:25 am - 7:18 pmSCL-PDX
22h 53m2 stops
$954Delta
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Mon, Jan 19 - Wed, Mar 25
Delta Logo
12:55 am - 7:00 amPDX-SCL
25h 05m2 stops
Delta Logo
12:25 am - 7:18 pmSCL-PDX
22h 53m2 stops
$959Delta
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Mon, Mar 2 - Mon, Mar 16

Air Canada flights from Portland to Santiago

Our best Air Canada deals on Portland to Santiago flight tickets
Air Canada
Feb 2
PDX9:50 amPortland
21h 25m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 12
SCL8:55 pmSantiago Arturo Merino Benitez
26h 35m
2 stops
PDX6:30 pmPortland
$875
Find similar
Air Canada
Mar 3
PDX3:15 pmPortland
58h 45m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Mar 17
SCL7:55 pmSantiago Arturo Merino Benitez
26h 35m
2 stops
PDX6:30 pmPortland
$919
Find similar
Air Canada
Mar 9
PDX9:50 amPortland
21h 25m
2 stops
SCL11:15 amSantiago Arturo Merino Benitez
Mar 19
SCL7:55 pmSantiago Arturo Merino Benitez
41h 20m
2 stops
PDX9:15 amPortland
$926
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LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Jan 22
PDX7:00 amPortland
18h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 23
SCL11:55 pmSantiago Arturo Merino Benitez
15h 58m
1 stop
PDX11:53 amPortland
$912
Find similar
LATAM Airlines
Nov 13
PDX7:05 amPortland
18h 50m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Nov 25
SCL11:35 pmSantiago Arturo Merino Benitez
17h 11m
1 stop
PDX11:46 amPortland
$913
Find similar
LATAM Airlines
Nov 13
PDX7:05 amPortland
18h 50m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Nov 25
SCL11:35 pmSantiago Arturo Merino Benitez
17h 11m
1 stop
PDX11:46 amPortland
$915
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 1/24

5:50 pm-5:35 am

1 stop30h 45m

Santiago Arturo Merino Benitez

Tue 3/31

3:30 pm-8:30 pm

2 stops33h 00m

$834

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

1:21 pm-6:30 am

1 stop36h 09m

Santiago Arturo Merino Benitez

Tue 11/25

9:05 pm-8:44 pm

2 stops28h 39m

$854

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 2/2

9:50 am-12:15 pm

2 stops21h 25m

Santiago Arturo Merino Benitez

Thu 2/12

8:55 pm-6:30 pm

2 stops26h 35m

$875

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 1/22

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Mon 3/23

11:55 pm-11:53 am

1 stop15h 58m

$912

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

7:05 am-6:55 am

1 stop18h 50m

Santiago Arturo Merino Benitez

Tue 11/25

11:35 pm-11:46 am

1 stop17h 11m

$913

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 3/3

3:15 pm-7:00 am

2 stops58h 45m

Santiago Arturo Merino Benitez

Tue 3/17

7:55 pm-6:30 pm

2 stops26h 35m

$919

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

1:15 pm-8:50 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Tue 11/25

10:45 pm-9:26 pm

2 stops27h 41m

$946

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

6:00 am-8:50 am

3 stops21h 50m

Santiago Arturo Merino Benitez

Tue 11/25

10:45 pm-1:47 pm

2 stops20h 02m

$948

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 1/19

11:59 am-2:05 pm

2 stops21h 06m

Santiago Arturo Merino Benitez

Wed 3/25

12:25 am-7:18 pm

2 stops22h 53m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/2

12:55 am-7:00 am

2 stops25h 05m

Santiago Arturo Merino Benitez

Mon 3/16

12:25 am-7:18 pm

2 stops22h 53m

$959

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland and Santiago?

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $1,022. If you don’t want to visit Santiago in January, then you should wait until October to fly from Portland, when ticket prices are also cheap, with an average price of $1,031.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,156 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $985 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 13% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Direct flights

None
There are no direct flights from Portland to Santiago. There are no popular flight routes from Portland to Santiago.
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  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $862Free CancellationRating
7.9
7,993 reviews
Search Delta flights
LATAM AirlinesPriceFrom $882Free CancellationRating
7.5
1,872 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $953Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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