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Cheap flights from Portland to Santiago from $312

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

LATAM Airlines Logo
10:00 am - 6:00 amPDX-SCL
15h 00m1 stop
LATAM Airlines Logo
11:55 pm - 11:54 amSCL-PDX
16h 59m1 stop
$906LATAM Airlines
Find Deal
Mon, Nov 17 - Mon, Dec 15
Logo
1:23 pm - 6:00 amPDX-SCL
37h 37m1 stop
Logo
11:00 am - 12:12 amSCL-PDX
41h 12m2 stops
$915
Find Deal
Sun, Aug 31 - Sun, Sep 28
LATAM Airlines Logo
10:23 am - 6:00 amPDX-SCL
14h 37m1 stop
LATAM Airlines Logo
11:55 pm - 11:54 amSCL-PDX
16h 59m1 stop
$924LATAM Airlines
Find Deal
Mon, Nov 3 - Thu, Nov 13
LATAM Airlines Logo
9:45 pm - 5:40 amPDX-SCL
26h 55m2 stops
LATAM Airlines Logo
11:55 pm - 11:54 amSCL-PDX
16h 59m1 stop
$927LATAM Airlines
Find Deal
Mon, Nov 17 - Mon, Dec 15
LATAM Airlines Logo
10:23 am - 6:00 amPDX-SCL
14h 37m1 stop
LATAM Airlines Logo
11:25 pm - 1:26 pmSCL-PDX
19h 01m2 stops
$928LATAM Airlines
Find Deal
Mon, Nov 3 - Thu, Nov 13
LATAM Airlines Logo
10:23 am - 6:00 amPDX-SCL
14h 37m1 stop
LATAM Airlines Logo
8:10 am - 10:20 pmSCL-PDX
19h 10m2 stops
$939LATAM Airlines
Find Deal
Wed, Nov 5 - Sun, Nov 16
Delta Logo
12:40 am - 6:00 amPDX-SCL
24h 20m2 stops
Delta Logo
11:55 pm - 11:54 amSCL-PDX
16h 59m1 stop
$978Delta
Find Deal
Sun, Nov 16 - Mon, Dec 15
Delta Logo
12:40 am - 6:00 amPDX-SCL
24h 20m2 stops
Delta Logo
11:15 pm - 10:56 amSCL-PDX
16h 41m1 stop
$1,058Delta
Find Deal
Thu, Nov 27 - Sat, Dec 13
American Airlines Logo
1:44 am - 7:50 amPDX-SCL
25h 06m1 stop
American Airlines Logo
11:15 pm - 10:28 amSCL-PDX
16h 13m1 stop
$1,114American Airlines
Find Deal
Sun, Dec 28 - Sun, Jan 11
American Airlines Logo
5:34 am - 6:55 amPDX-SCL
22h 21m2 stops
American Airlines Logo
9:55 pm - 6:54 pmSCL-PDX
24h 59m2 stops
$1,138American Airlines
Find Deal
Thu, Aug 28 - Tue, Sep 23

American Airlines flights from Portland to Santiago

Our best American Airlines deals on Portland to Santiago flight tickets
American Airlines
Dec 28
PDX1:44 amPortland
25h 06m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Jan 11
SCL11:15 pmSantiago Arturo Merino Benitez
16h 13m
1 stop
PDX10:28 amPortland
$1,114
Find similar
American Airlines
Aug 28
PDX5:34 amPortland
22h 21m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Sep 23
SCL9:55 pmSantiago Arturo Merino Benitez
24h 59m
2 stops
PDX6:54 pmPortland
$1,138
Find similar
American Airlines
Aug 31
PDX11:59 pmPortland
27h 56m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Sep 29
SCL9:55 pmSantiago Arturo Merino Benitez
18h 55m
2 stops
PDX12:50 pmPortland
$1,248
Find similar

LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Nov 17
PDX10:00 amPortland
15h 00m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Dec 15
SCL11:55 pmSantiago Arturo Merino Benitez
16h 59m
1 stop
PDX11:54 amPortland
$906
Find similar
LATAM Airlines
Nov 3
PDX10:23 amPortland
14h 37m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Nov 13
SCL11:55 pmSantiago Arturo Merino Benitez
16h 59m
1 stop
PDX11:54 amPortland
$924
Find similar
LATAM Airlines
Nov 17
PDX9:45 pmPortland
26h 55m
2 stops
SCL5:40 amSantiago Arturo Merino Benitez
Dec 15
SCL11:55 pmSantiago Arturo Merino Benitez
16h 59m
1 stop
PDX11:54 amPortland
$927
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 11/17

10:00 am-6:00 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Mon 12/15

11:55 pm-11:54 am

1 stop16h 59m

$906

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 8/31

1:23 pm-6:00 am

1 stop37h 37m

Santiago Arturo Merino Benitez

Sun 9/28

11:00 am-12:12 am

2 stops41h 12m

$915

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 11/3

10:23 am-6:00 am

1 stop14h 37m

Santiago Arturo Merino Benitez

Thu 11/13

11:55 pm-11:54 am

1 stop16h 59m

$924

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 11/17

9:45 pm-5:40 am

2 stops26h 55m

Santiago Arturo Merino Benitez

Mon 12/15

11:55 pm-11:54 am

1 stop16h 59m

$927

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 11/3

10:23 am-6:00 am

1 stop14h 37m

Santiago Arturo Merino Benitez

Thu 11/13

11:25 pm-1:26 pm

2 stops19h 01m

$928

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 11/5

10:23 am-6:00 am

1 stop14h 37m

Santiago Arturo Merino Benitez

Sun 11/16

8:10 am-10:20 pm

2 stops19h 10m

$939

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 11/16

12:40 am-6:00 am

2 stops24h 20m

Santiago Arturo Merino Benitez

Mon 12/15

11:55 pm-11:54 am

1 stop16h 59m

$978

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/27

12:40 am-6:00 am

2 stops24h 20m

Santiago Arturo Merino Benitez

Sat 12/13

11:15 pm-10:56 am

1 stop16h 41m

$1,058

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 12/28

1:44 am-7:50 am

1 stop25h 06m

Santiago Arturo Merino Benitez

Sun 1/11

11:15 pm-10:28 am

1 stop16h 13m

$1,114

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 8/28

5:34 am-6:55 am

2 stops22h 21m

Santiago Arturo Merino Benitez

Tue 9/23

9:55 pm-6:54 pm

2 stops24h 59m

$1,138

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland and Santiago?

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $973. If you don’t want to visit Santiago in October, then you should wait until January to fly from Portland, when ticket prices are also cheap, with an average price of $1,029.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,128 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $982 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Best Price Found

$312

Fastest flight time

14h 37m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Portland in the past 72 hours is $312. The best round-trip flight deal from Portland to Santiago found on momondo in the last 72 hours is $906.
The fastest flight from Portland to Santiago takes 14h 37m
There are no direct flights from Portland to Santiago. Popular non-direct route for this connection is Portland Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 37m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $882Free CancellationRating
7.5
1,841 reviews
Search LATAM Airlines flights
DeltaPriceFrom $942Free CancellationRating
8.0
7,986 reviews
Search Delta flights
United AirlinesPriceFrom $972Free CancellationRating
7.4
8,919 reviews
Search United Airlines flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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