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Cheap flights from Portland to Santiago from $422

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:20 am - 7:40 amPDX-SCL
19h 20m2 stops
Multiple Airlines Logo
11:55 pm - 12:05 pmSCL-PDX
17h 10m1 stop
$772Multiple Airlines
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Wed, Jan 14 - Sun, Feb 8
Multiple Airlines Logo
7:18 am - 3:35 amPDX-SCL
39h 17m2 stops
Multiple Airlines Logo
10:35 am - 8:50 pmSCL-PDX
39h 15m1 stop
$810Multiple Airlines
Find Deal
Wed, Dec 10 - Wed, Dec 17
Multiple Airlines Logo
7:00 am - 10:15 pmPDX-SCL
34h 15m2 stops
Multiple Airlines Logo
11:55 pm - 4:54 pmSCL-PDX
20h 59m1 stop
$861Multiple Airlines
Find Deal
Thu, Mar 5 - Wed, Mar 11
Multiple Airlines Logo
5:50 pm - 5:35 amPDX-SCL
30h 45m2 stops
Multiple Airlines Logo
11:55 pm - 4:37 pmSCL-PDX
21h 42m1 stop
$865Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
9:48 pm - 5:35 amPDX-SCL
26h 47m2 stops
Multiple Airlines Logo
11:55 pm - 4:54 pmSCL-PDX
20h 59m1 stop
$866Multiple Airlines
Find Deal
Sat, Feb 28 - Wed, Mar 11
Multiple Airlines Logo
7:00 am - 10:15 pmPDX-SCL
34h 15m2 stops
Multiple Airlines Logo
11:55 pm - 4:54 pmSCL-PDX
20h 59m1 stop
$867Multiple Airlines
Find Deal
Fri, Mar 6 - Wed, Mar 11
Air Canada Logo
9:40 am - 12:15 pmPDX-SCL
21h 35m2 stops
Air Canada Logo
7:55 pm - 2:40 pmSCL-PDX
22h 45m2 stops
$872Air Canada
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Tue, Mar 3 - Tue, Mar 10
Multiple Airlines Logo
2:47 pm - 5:35 amPDX-SCL
33h 48m2 stops
Multiple Airlines Logo
11:55 pm - 4:54 pmSCL-PDX
20h 59m1 stop
$880Multiple Airlines
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Mon, Mar 2 - Wed, Mar 11
Multiple Airlines Logo
7:05 am - 7:00 amPDX-SCL
42h 55m2 stops
Multiple Airlines Logo
11:55 pm - 4:54 pmSCL-PDX
20h 59m1 stop
$883Multiple Airlines
Find Deal
Sun, Mar 1 - Wed, Mar 11
LATAM Airlines Logo
7:00 am - 6:55 amPDX-SCL
18h 55m1 stop
LATAM Airlines Logo
11:55 pm - 12:04 pmSCL-PDX
17h 09m1 stop
$891LATAM Airlines
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Wed, Jan 14 - Tue, Feb 3

American Airlines flights from Portland to Santiago

Our best American Airlines deals on Portland to Santiago flight tickets
American Airlines
Dec 23
PDX10:49 pmPortland
28h 06m
1 stop
SCL7:55 amSantiago Arturo Merino Benitez
Mar 4
SCL11:15 pmSantiago Arturo Merino Benitez
16h 54m
1 stop
PDX11:09 amPortland
$972
Find similar
American Airlines
Nov 17
PDX6:00 amPortland
20h 55m
2 stops
SCL7:55 amSantiago Arturo Merino Benitez
Dec 15
SCL11:15 pmSantiago Arturo Merino Benitez
24h 55m
1 stop
PDX7:10 pmPortland
$1,309
Find similar
American Airlines
Nov 13
PDX5:30 amPortland
21h 25m
1 stop
SCL7:55 amSantiago Arturo Merino Benitez
Nov 25
SCL11:15 pmSantiago Arturo Merino Benitez
28h 44m
1 stop
PDX10:59 pmPortland
$1,311
Find similar

LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Jan 14
PDX7:00 amPortland
18h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Feb 3
SCL11:55 pmSantiago Arturo Merino Benitez
17h 09m
1 stop
PDX12:04 pmPortland
$891
Find similar
LATAM Airlines
Dec 10
PDX11:54 amPortland
14h 46m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 17
SCL11:55 pmSantiago Arturo Merino Benitez
16h 55m
1 stop
PDX11:50 amPortland
$910
Find similar
LATAM Airlines
Jan 14
PDX7:00 amPortland
18h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Feb 3
SCL8:50 pmSantiago Arturo Merino Benitez
20h 14m
2 stops
PDX12:04 pmPortland
$912
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 1/14

7:20 am-7:40 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Sun 2/8

11:55 pm-12:05 pm

1 stop17h 10m

$772

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 12/10

7:18 am-3:35 am

2 stops39h 17m

Santiago Arturo Merino Benitez

Wed 12/17

10:35 am-8:50 pm

1 stop39h 15m

$810

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 3/5

7:00 am-10:15 pm

2 stops34h 15m

Santiago Arturo Merino Benitez

Wed 3/11

11:55 pm-4:54 pm

1 stop20h 59m

$861

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 12/4

5:50 pm-5:35 am

2 stops30h 45m

Santiago Arturo Merino Benitez

Sun 12/7

11:55 pm-4:37 pm

1 stop21h 42m

$865

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 2/28

9:48 pm-5:35 am

2 stops26h 47m

Santiago Arturo Merino Benitez

Wed 3/11

11:55 pm-4:54 pm

1 stop20h 59m

$866

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Fri 3/6

7:00 am-10:15 pm

2 stops34h 15m

Santiago Arturo Merino Benitez

Wed 3/11

11:55 pm-4:54 pm

1 stop20h 59m

$867

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 3/3

9:40 am-12:15 pm

2 stops21h 35m

Santiago Arturo Merino Benitez

Tue 3/10

7:55 pm-2:40 pm

2 stops22h 45m

$872

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/2

2:47 pm-5:35 am

2 stops33h 48m

Santiago Arturo Merino Benitez

Wed 3/11

11:55 pm-4:54 pm

1 stop20h 59m

$880

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 3/1

7:05 am-7:00 am

2 stops42h 55m

Santiago Arturo Merino Benitez

Wed 3/11

11:55 pm-4:54 pm

1 stop20h 59m

$883

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 1/14

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 2/3

11:55 pm-12:04 pm

1 stop17h 09m

$891

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $977. If you don’t want to visit Santiago in January, then you should wait until July to fly from Portland, when ticket prices are also cheap, with an average price of $1,013.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,132 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $952 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 13% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Direct flights

None
There are no direct flights from Portland to Santiago. There are no popular flight routes from Portland to Santiago.
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  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $862Free CancellationRating
7.9
8,008 reviews
Search Delta flights
LATAM AirlinesPriceFrom $882Free CancellationRating
7.5
1,873 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $953Free CancellationRating
7.4
9,015 reviews
Search United Airlines flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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