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Cheap flights from Portland to Santiago from $329

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

Logo
1:21 pm - 8:21 pmPDX-SCL
26h 00m2 stops
Logo
5:50 am - 5:36 pmSCL-PDX
40h 46m3 stops
$818
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Thu, Nov 13 - Tue, Nov 25
Logo
12:33 pm - 6:25 amPDX-SCL
36h 52m3 stops
Logo
5:50 am - 5:36 pmSCL-PDX
40h 46m3 stops
$849
Find Deal
Thu, Nov 13 - Tue, Nov 25
LATAM Airlines Logo
6:00 am - 5:50 amPDX-SCL
19h 50m2 stops
LATAM Airlines Logo
6:30 pm - 11:46 amSCL-PDX
22h 16m2 stops
$870LATAM Airlines
Find Deal
Wed, Oct 29 - Sun, Nov 9
LATAM Airlines Logo
7:12 am - 5:45 amPDX-SCL
18h 33m1 stop
LATAM Airlines Logo
8:45 pm - 4:12 pmSCL-PDX
23h 27m2 stops
$891LATAM Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Air Canada Logo
7:00 pm - 11:15 amPDX-SCL
36h 15m2 stops
Air Canada Logo
7:55 pm - 2:45 pmSCL-PDX
22h 50m2 stops
$903Air Canada
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Sun, Mar 8 - Mon, Mar 16
United Airlines Logo
7:30 am - 8:50 amPDX-SCL
20h 20m2 stops
United Airlines Logo
10:45 pm - 1:47 pmSCL-PDX
20h 02m2 stops
$950United Airlines
Find Deal
Thu, Nov 13 - Tue, Nov 25
United Airlines Logo
1:15 pm - 8:50 amPDX-SCL
14h 35m1 stop
United Airlines Logo
10:45 pm - 2:46 pmSCL-PDX
21h 01m2 stops
$951United Airlines
Find Deal
Thu, Nov 13 - Tue, Nov 25
Delta Logo
6:00 am - 6:35 amPDX-SCL
19h 35m2 stops
Delta Logo
11:10 pm - 7:31 pmSCL-PDX
25h 21m1 stop
$954Delta
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Mon, Nov 17 - Mon, Dec 15
Delta Logo
12:35 am - 6:00 amPDX-SCL
24h 25m2 stops
Delta Logo
11:10 pm - 10:41 amSCL-PDX
16h 31m1 stop
$958Delta
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Sun, Nov 16 - Mon, Dec 15
Air Canada Logo
7:00 pm - 12:15 pmPDX-SCL
36h 15m2 stops
Air Canada Logo
8:35 am - 2:45 pmSCL-PDX
35h 10m2 stops
$979Air Canada
Find Deal
Sat, Jan 17 - Sun, Jan 25

Delta flights from Portland to Santiago

Our best Delta deals on Portland to Santiago flight tickets
Delta
Nov 17
PDX6:00 amPortland
19h 35m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Dec 15
SCL11:10 pmSantiago Arturo Merino Benitez
25h 21m
1 stop
PDX7:31 pmPortland
$954
Find similar
Delta
Nov 16
PDX12:35 amPortland
24h 25m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
Dec 15
SCL11:10 pmSantiago Arturo Merino Benitez
16h 31m
1 stop
PDX10:41 amPortland
$958
Find similar
Delta
Mar 9
PDX6:04 amPortland
18h 26m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
Mar 18
SCL12:25 amSantiago Arturo Merino Benitez
22h 53m
2 stops
PDX7:18 pmPortland
$974
Find similar

LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Oct 29
PDX6:00 amPortland
19h 50m
2 stops
SCL5:50 amSantiago Arturo Merino Benitez
Nov 9
SCL6:30 pmSantiago Arturo Merino Benitez
22h 16m
2 stops
PDX11:46 amPortland
$870
Find similar
LATAM Airlines
Oct 14
PDX7:12 amPortland
18h 33m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
Oct 21
SCL8:45 pmSantiago Arturo Merino Benitez
23h 27m
2 stops
PDX4:12 pmPortland
$891
Find similar
LATAM Airlines
Oct 14
PDX6:00 amPortland
18h 30m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
Oct 21
SCL8:45 pmSantiago Arturo Merino Benitez
23h 27m
2 stops
PDX4:12 pmPortland
$912
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

1:21 pm-8:21 pm

2 stops26h 00m

Santiago Arturo Merino Benitez

Tue 11/25

5:50 am-5:36 pm

3 stops40h 46m

$818

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

12:33 pm-6:25 am

3 stops36h 52m

Santiago Arturo Merino Benitez

Tue 11/25

5:50 am-5:36 pm

3 stops40h 46m

$849

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 10/29

6:00 am-5:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Sun 11/9

6:30 pm-11:46 am

2 stops22h 16m

$870

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 10/14

7:12 am-5:45 am

1 stop18h 33m

Santiago Arturo Merino Benitez

Tue 10/21

8:45 pm-4:12 pm

2 stops23h 27m

$891

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 3/8

7:00 pm-11:15 am

2 stops36h 15m

Santiago Arturo Merino Benitez

Mon 3/16

7:55 pm-2:45 pm

2 stops22h 50m

$903

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

7:30 am-8:50 am

2 stops20h 20m

Santiago Arturo Merino Benitez

Tue 11/25

10:45 pm-1:47 pm

2 stops20h 02m

$950

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 11/13

1:15 pm-8:50 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Tue 11/25

10:45 pm-2:46 pm

2 stops21h 01m

$951

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 11/17

6:00 am-6:35 am

2 stops19h 35m

Santiago Arturo Merino Benitez

Mon 12/15

11:10 pm-7:31 pm

1 stop25h 21m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 11/16

12:35 am-6:00 am

2 stops24h 25m

Santiago Arturo Merino Benitez

Mon 12/15

11:10 pm-10:41 am

1 stop16h 31m

$958

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 1/17

7:00 pm-12:15 pm

2 stops36h 15m

Santiago Arturo Merino Benitez

Sun 1/25

8:35 am-2:45 pm

2 stops35h 10m

$979

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $1,002. If you don’t want to visit Santiago in October, then you should wait until September to fly from Portland, when ticket prices are also cheap, with an average price of $1,033.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,143 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $985 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 18% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Direct flights

None
There are no direct flights from Portland to Santiago. There are no popular flight routes from Portland to Santiago.
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  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $882Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
DeltaPriceFrom $942Free CancellationRating
7.9
7,956 reviews
Search Delta flights
United AirlinesPriceFrom $972Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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