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Cheap flights from Portland to Santiago from $399

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:00 am - 10:15 pm
PDX
-
SCL
35h 15m2 stops
Multiple Airlines Logo
11:00 pm - 8:30 pm
SCL
-
PDX
25h 30m1 stop
$785Multiple Airlines
mié., mar. 18 - mar., mar. 31
Multiple Airlines Logo
7:00 am - 10:15 pm
PDX
-
SCL
35h 15m2 stops
Multiple Airlines Logo
11:25 pm - 8:30 pm
SCL
-
PDX
25h 05m1 stop
$797Multiple Airlines
mar., mar. 17 - mar., mar. 24
Multiple Airlines Logo
7:00 am - 6:40 am
PDX
-
SCL
19h 40m2 stops
Multiple Airlines Logo
11:25 pm - 8:30 pm
SCL
-
PDX
25h 05m1 stop
$802Multiple Airlines
lun., mar. 16 - mar., mar. 24
Multiple Airlines Logo
10:51 pm - 5:30 am
PDX
-
SCL
25h 39m2 stops
Multiple Airlines Logo
11:55 pm - 12:05 pm
SCL
-
PDX
17h 10m1 stop
$806Multiple Airlines
mar., feb. 17 - jue., feb. 26
Multiple Airlines Logo
7:00 am - 6:40 am
PDX
-
SCL
19h 40m2 stops
Multiple Airlines Logo
11:25 pm - 8:30 pm
SCL
-
PDX
25h 05m1 stop
$818Multiple Airlines
dom., mar. 15 - mar., mar. 24
Multiple Airlines Logo
7:20 am - 7:40 am
PDX
-
SCL
19h 20m2 stops
Multiple Airlines Logo
11:55 pm - 1:41 pm
SCL
-
PDX
18h 46m1 stop
$827Multiple Airlines
mar., ene. 20 - mar., ene. 27
Multiple Airlines Logo
10:51 pm - 5:30 am
PDX
-
SCL
25h 39m2 stops
Multiple Airlines Logo
11:55 pm - 12:05 pm
SCL
-
PDX
17h 10m1 stop
$828Multiple Airlines
sáb., feb. 14 - jue., feb. 26
Multiple Airlines Logo
10:51 pm - 5:30 am
PDX
-
SCL
25h 39m2 stops
Multiple Airlines Logo
11:25 pm - 8:44 pm
SCL
-
PDX
26h 19m1 stop
$838Multiple Airlines
mar., feb. 17 - mié., feb. 25
Multiple Airlines Logo
7:00 am - 10:15 pm
PDX
-
SCL
35h 15m2 stops
Multiple Airlines Logo
11:25 pm - 8:30 pm
SCL
-
PDX
25h 05m1 stop
$839Multiple Airlines
jue., mar. 12 - mar., mar. 24
Air Canada Logo
9:50 am - 12:15 pm
PDX
-
SCL
21h 25m2 stops
Air Canada Logo
7:55 pm - 6:30 pm
SCL
-
PDX
26h 35m2 stops
$843Air Canada
mar., mar. 3 - mar., mar. 17

LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Mar 9
PDX7:00 amPortland
18h 55m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 19
SCL11:55 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
PDX12:10 pmPortland
$912
Find similar
LATAM Airlines
Jan 20
PDX6:25 amPortland
18h 10m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
Jan 27
SCL11:55 pmSantiago Arturo Merino Benitez
17h 05m
1 stop
PDX12:00 pmPortland
$922
Find similar
LATAM Airlines
Mar 14
PDX7:00 amPortland
18h 55m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 25
SCL11:55 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
PDX12:10 pmPortland
$927
Find similar

Delta flights from Portland to Santiago

Our best Delta deals on Portland to Santiago flight tickets
Delta
Mar 16
PDX11:40 amPortland
16h 00m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 1
SCL8:40 pmSantiago Arturo Merino Benitez
17h 45m
1 stop
PDX10:25 amPortland
$964
Find similar
Delta
Dec 13
PDX10:10 pmPortland
28h 30m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 24
SCL9:30 pmSantiago Arturo Merino Benitez
26h 23m
1 stop
PDX6:53 pmPortland
$999
Find similar
Delta
Dec 13
PDX10:10 pmPortland
28h 30m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 24
SCL11:10 pmSantiago Arturo Merino Benitez
26h 24m
2 stops
PDX8:34 pmPortland
$1,004
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mié. 3/18

7:00 am-10:15 pm

2 stops35h 15m

Santiago Arturo Merino Benitez

mar. 3/31

11:00 pm-8:30 pm

1 stop25h 30m

$785

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mar. 3/17

7:00 am-10:15 pm

2 stops35h 15m

Santiago Arturo Merino Benitez

mar. 3/24

11:25 pm-8:30 pm

1 stop25h 05m

$797

PortlandSantiago

PDX - SCL

PDXSCL

Portland

lun. 3/16

7:00 am-6:40 am

2 stops19h 40m

Santiago Arturo Merino Benitez

mar. 3/24

11:25 pm-8:30 pm

1 stop25h 05m

$802

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mar. 2/17

10:51 pm-5:30 am

2 stops25h 39m

Santiago Arturo Merino Benitez

jue. 2/26

11:55 pm-12:05 pm

1 stop17h 10m

$806

PortlandSantiago

PDX - SCL

PDXSCL

Portland

dom. 3/15

7:00 am-6:40 am

2 stops19h 40m

Santiago Arturo Merino Benitez

mar. 3/24

11:25 pm-8:30 pm

1 stop25h 05m

$818

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mar. 1/20

7:20 am-7:40 am

2 stops19h 20m

Santiago Arturo Merino Benitez

mar. 1/27

11:55 pm-1:41 pm

1 stop18h 46m

$827

PortlandSantiago

PDX - SCL

PDXSCL

Portland

sáb. 2/14

10:51 pm-5:30 am

2 stops25h 39m

Santiago Arturo Merino Benitez

jue. 2/26

11:55 pm-12:05 pm

1 stop17h 10m

$828

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mar. 2/17

10:51 pm-5:30 am

2 stops25h 39m

Santiago Arturo Merino Benitez

mié. 2/25

11:25 pm-8:44 pm

1 stop26h 19m

$838

PortlandSantiago

PDX - SCL

PDXSCL

Portland

jue. 3/12

7:00 am-10:15 pm

2 stops35h 15m

Santiago Arturo Merino Benitez

mar. 3/24

11:25 pm-8:30 pm

1 stop25h 05m

$839

PortlandSantiago

PDX - SCL

PDXSCL

Portland

mar. 3/3

9:50 am-12:15 pm

2 stops21h 25m

Santiago Arturo Merino Benitez

mar. 3/17

7:55 pm-6:30 pm

2 stops26h 35m

$843

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $988. If you don’t want to visit Santiago in January, then you should wait until July to fly from Portland, when ticket prices are also cheap, with an average price of $1,013.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,132 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $952 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 6% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Fastest flight time

19h 20m

Direct flights

None
The fastest flight from Portland to Santiago takes 19h 20m
There are no direct flights from Portland to Santiago. There are no popular flight routes from Portland to Santiago.
Search flight deals

  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 37m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $874Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $953Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
DeltaPriceFrom $954Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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