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Cheap flights from Portland to Santiago from $378

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
7:00 am - 6:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
11:55 pm - 12:02 pm
SCL
-
PDX
17h 07m1 stop
$891LATAM Airlines
Wed, Feb 4 - Wed, Feb 18
LATAM Airlines Logo
7:00 am - 5:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
11:55 pm - 12:10 pm
SCL
-
PDX
16h 15m1 stop
$912LATAM Airlines
Mon, Mar 9 - Thu, Mar 19
LATAM Airlines Logo
7:00 am - 6:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
11:00 pm - 7:03 pm
SCL
-
PDX
24h 03m2 stops
$917LATAM Airlines
Tue, Mar 3 - Mon, Mar 30
LATAM Airlines Logo
7:00 am - 5:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
11:55 pm - 12:10 pm
SCL
-
PDX
16h 15m1 stop
$927LATAM Airlines
Sat, Mar 14 - Wed, Mar 25
LATAM Airlines Logo
7:00 am - 5:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
12:20 am - 7:03 pm
SCL
-
PDX
22h 43m2 stops
$933LATAM Airlines
Mon, Mar 9 - Wed, Mar 18
LATAM Airlines Logo
11:40 am - 2:10 pm
PDX
-
SCL
22h 30m3 stops
LATAM Airlines Logo
11:55 pm - 12:10 pm
SCL
-
PDX
16h 15m1 stop
$938LATAM Airlines
Tue, Mar 17 - Wed, Mar 25
LATAM Airlines Logo
5:00 pm - 5:25 pm
PDX
-
SCL
19h 25m2 stops
LATAM Airlines Logo
11:10 pm - 10:47 am
SCL
-
PDX
16h 37m1 stop
$947LATAM Airlines
Tue, Jan 13 - Tue, Jan 20
LATAM Airlines Logo
7:00 am - 6:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
11:10 pm - 7:13 pm
SCL
-
PDX
25h 03m1 stop
$948LATAM Airlines
Sun, Jan 18 - Tue, Jan 27
LATAM Airlines Logo
7:00 am - 5:55 am
PDX
-
SCL
18h 55m1 stop
LATAM Airlines Logo
8:50 am - 10:25 am
SCL
-
PDX
29h 35m2 stops
$954LATAM Airlines
Mon, Mar 9 - Thu, Mar 19
United Airlines Logo
7:51 pm - 8:50 am
PDX
-
SCL
31h 59m2 stops
United Airlines Logo
10:45 pm - 6:10 pm
SCL
-
PDX
24h 25m2 stops
$959United Airlines
Sun, Jan 18 - Tue, Jan 27

LATAM Airlines flights from Portland to Santiago

Our best LATAM Airlines deals on Portland to Santiago flight tickets
LATAM Airlines
Feb 4
PDX7:00 amPortland
18h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Feb 18
SCL11:55 pmSantiago Arturo Merino Benitez
17h 07m
1 stop
PDX12:02 pmPortland
$891
Find similar
LATAM Airlines
Mar 9
PDX7:00 amPortland
18h 55m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 19
SCL11:55 pmSantiago Arturo Merino Benitez
16h 15m
1 stop
PDX12:10 pmPortland
$912
Find similar
LATAM Airlines
Mar 3
PDX7:00 amPortland
18h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 30
SCL11:00 pmSantiago Arturo Merino Benitez
24h 03m
2 stops
PDX7:03 pmPortland
$917
Find similar

United Airlines flights from Portland to Santiago

Our best United Airlines deals on Portland to Santiago flight tickets
United Airlines
Jan 18
PDX7:51 pmPortland
31h 59m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Jan 27
SCL10:45 pmSantiago Arturo Merino Benitez
24h 25m
2 stops
PDX6:10 pmPortland
$959
Find similar
United Airlines
Feb 7
PDX7:51 pmPortland
55h 59m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Feb 20
SCL10:45 pmSantiago Arturo Merino Benitez
18h 37m
1 stop
PDX12:22 pmPortland
$1,019
Find similar
United Airlines
Dec 22
PDX5:00 amPortland
46h 50m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Jan 22
SCL10:45 pmSantiago Arturo Merino Benitez
25h 11m
2 stops
PDX6:56 pmPortland
$1,072
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Wed 2/4

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Wed 2/18

11:55 pm-12:02 pm

1 stop17h 07m

$891

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/19

11:55 pm-12:10 pm

1 stop16h 15m

$912

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 3/3

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-7:03 pm

2 stops24h 03m

$917

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 3/14

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Wed 3/25

11:55 pm-12:10 pm

1 stop16h 15m

$927

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Wed 3/18

12:20 am-7:03 pm

2 stops22h 43m

$933

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 3/17

11:40 am-2:10 pm

3 stops22h 30m

Santiago Arturo Merino Benitez

Wed 3/25

11:55 pm-12:10 pm

1 stop16h 15m

$938

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 1/13

5:00 pm-5:25 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 1/20

11:10 pm-10:47 am

1 stop16h 37m

$947

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 1/18

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 1/27

11:10 pm-7:13 pm

1 stop25h 03m

$948

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/19

8:50 am-10:25 am

2 stops29h 35m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 1/18

7:51 pm-8:50 am

2 stops31h 59m

Santiago Arturo Merino Benitez

Tue 1/27

10:45 pm-6:10 pm

2 stops24h 25m

$959

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Portland to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from Portland to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $1,000. If you don’t want to visit Santiago in January, then you should wait until October to fly from Portland, when ticket prices are also cheap, with an average price of $1,030.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $1,144. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,372.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Portland to Santiago when you can find flight prices for as low as $972. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,236 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,139 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Portland for as low as $920 on momondo.

Can stopping save me money on Portland to Santiago flights?

You could potentially save up to 8% on your flight if you consider stops on a Portland to Santiago flight.

When to book flights from Portland to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago (PDX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago

Fastest flight time

14h 51m

Direct flights

None
The fastest flight from Portland to Santiago takes 14h 51m
There are no direct flights from Portland to Santiago. There are no popular flight routes from Portland to Santiago.
Search flight deals

  • How far is Portland to Santiago Arturo Merino Benitez by plane?

    Portland and Santiago Arturo Merino Benitez are 6346.8 mi apart from one another. Flights usually cover this in 14h 51m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Portland Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Portland Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Santiago?

Best airlines flying from Portland to Santiago

Compare and see reviews for airlines that fly from Portland to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $904Free CancellationRating
7.5
1,891 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $953Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
DeltaPriceFrom $958Free CancellationRating
7.9
8,009 reviews
Search Delta flights
American AirlinesPriceFrom $973Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Portland to Santiago for you.

Can I find flights from Portland to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Portland with this policy.

How can momondo help me find flights from Portland to Santiago?

Once all potential Portland to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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