Latest deals
When to book
FAQs
Price Alerts

Cheap flights from Panama City to Chicago from $264

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 3/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:27 pm - 10:28 pm
PTY
-
MDW
8h 01m
1 stop
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
$582Delta
Thu, Apr 16 - Sun, Apr 19
Delta Logo
2:27 pm - 10:28 pm
PTY
-
MDW
8h 01m
1 stop
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
$593Delta
Sat, Apr 25 - Wed, Apr 29
Multiple Airlines Logo
7:50 pm - 10:25 pm
PTY
-
MDW
27h 35m
2 stops
Multiple Airlines Logo
6:25 am - 8:34 pm
MDW
-
PTY
13h 09m
1 stop
$648Multiple Airlines
Sat, Feb 21 - Thu, Feb 26
Multiple Airlines Logo
3:50 pm - 1:00 pm
PTY
-
MDW
21h 10m
2 stops
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
$683Multiple Airlines
Fri, Apr 24 - Sun, Apr 26
Delta Logo
3:15 pm - 10:31 pm
PTY
-
MDW
8h 16m
1 stop
Delta Logo
6:00 am - 1:50 pm
MDW
-
PTY
6h 50m
1 stop
$690Delta
Thu, Feb 26 - Wed, Mar 4
Delta Logo
2:27 pm - 10:28 pm
PTY
-
MDW
8h 01m
1 stop
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
$755Delta
Fri, Apr 24 - Tue, Apr 28
LATAM Airlines Logo
2:20 pm - 11:56 am
PTY
-
MDW
21h 36m
1 stop
LATAM Airlines Logo
6:00 am - 1:07 pm
MDW
-
PTY
7h 07m
1 stop
$763LATAM Airlines
Wed, Jul 1 - Tue, Jul 14
LATAM Airlines Logo
3:15 pm - 9:54 am
PTY
-
MDW
19h 39m
1 stop
LATAM Airlines Logo
6:40 pm - 1:50 pm
MDW
-
PTY
18h 10m
1 stop
$801LATAM Airlines
Sat, Feb 21 - Thu, Feb 26
Delta Logo
2:28 pm - 10:31 pm
PTY
-
MDW
8h 03m
1 stop
Delta Logo
6:00 am - 1:03 pm
MDW
-
PTY
7h 03m
1 stop
$851Delta
Thu, Mar 26 - Thu, Apr 2
Multiple Airlines Logo
12:33 pm - 11:53 pm
PTY
-
MDW
11h 20m
1 stop
Multiple Airlines Logo
9:20 am - 8:05 am
MDW
-
PTY
22h 45m
2 stops
$894Multiple Airlines
Fri, Mar 27 - Fri, Apr 3

Delta flights from Panama City to Chicago Midway Airport

Our best Delta deals on Panama City to Chicago Midway Airport flight tickets
Delta
Apr 16
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
Apr 19
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
$582
Delta
Apr 25
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
Apr 29
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
$593
Delta
Feb 26
PTY3:15 pmPanama City Tocumen Intl
8h 16m
1 stop
MDW10:31 pmChicago Midway
Mar 4
MDW6:00 amChicago Midway
6h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
$690

LATAM Airlines flights from Panama City to Chicago Midway Airport

Our best LATAM Airlines deals on Panama City to Chicago Midway Airport flight tickets
LATAM Airlines
Feb 20
PTY3:15 pmPanama City Tocumen Intl
8h 16m
1 stop
MDW10:31 pmChicago Midway
Mar 1
MDW6:40 pmChicago Midway
18h 10m
1 stop
PTY1:50 pmPanama City Tocumen Intl
$732
LATAM Airlines
Jul 1
PTY2:20 pmPanama City Tocumen Intl
21h 36m
1 stop
MDW11:56 amChicago Midway
Jul 14
MDW6:00 amChicago Midway
7h 07m
1 stop
PTY1:07 pmPanama City Tocumen Intl
$763
LATAM Airlines
Feb 18
PTY3:15 pmPanama City Tocumen Intl
19h 39m
1 stop
MDW9:54 amChicago Midway
Feb 23
MDW12:45 pmChicago Midway
24h 05m
1 stop
PTY1:50 pmPanama City Tocumen Intl
$764

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Panama City to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 4/16

2:27 pm-10:28 pm

1 stop8h 01m

Chicago Midway

Sun 4/19

6:00 am-1:02 pm

1 stop7h 02m

$582

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sat 4/25

2:27 pm-10:28 pm

1 stop8h 01m

Chicago Midway

Wed 4/29

6:00 am-1:02 pm

1 stop7h 02m

$593

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sat 2/21

7:50 pm-10:25 pm

2 stops27h 35m

Chicago Midway

Thu 2/26

6:25 am-8:34 pm

1 stop13h 09m

$648

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 4/24

3:50 pm-1:00 pm

2 stops21h 10m

Chicago Midway

Sun 4/26

6:00 am-8:34 pm

1 stop14h 34m

$683

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 2/26

3:15 pm-10:31 pm

1 stop8h 16m

Chicago Midway

Wed 3/4

6:00 am-1:50 pm

1 stop6h 50m

$690

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 4/24

2:27 pm-10:28 pm

1 stop8h 01m

Chicago Midway

Tue 4/28

6:00 am-1:02 pm

1 stop7h 02m

$755

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 7/1

2:20 pm-11:56 am

1 stop21h 36m

Chicago Midway

Tue 7/14

6:00 am-1:07 pm

1 stop7h 07m

$763

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sat 2/21

3:15 pm-9:54 am

1 stop19h 39m

Chicago Midway

Thu 2/26

6:40 pm-1:50 pm

1 stop18h 10m

$801

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 3/26

2:28 pm-10:31 pm

1 stop8h 03m

Chicago Midway

Thu 4/2

6:00 am-1:03 pm

1 stop7h 03m

$851

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 3/27

12:33 pm-11:53 pm

1 stop11h 20m

Chicago Midway

Fri 4/3

9:20 am-8:05 am

2 stops22h 45m

$894

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

When to book flights from Panama City to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago Midway Airport (PTY to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago Midway Airport

Fastest flight time

8h 01m

Direct flights

None
The fastest flight from Panama City to Chicago Midway Airport takes 8h 01m
There are no direct flights from Panama City to Chicago Midway Airport. There are no popular flight routes from Panama City to Chicago Midway Airport.
Search flight deals

  • How far is Panama City Tocumen Intl to Chicago Midway by plane?

    There are 2319.5 mi between Panama City Tocumen Intl and Chicago Midway. A reasonable flight in good conditions will take 8h 01m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago Midway Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago Midway Airport were last updated today.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The necessary travel and health documents for your Chicago Midway Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • How do I get Price Alerts for flights from Panama City to Chicago Midway Airport?

    You can take advantage of momondo’s Price Alerts by first searching for your flights to Panama City from Chicago Midway Airport. Flight offers will be shown to you in real-time. From there you can create a Price Alert by using our on-site widget.

  • How can I save money on flights from Panama City to Chicago Midway Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

Finding the right flight to Chicago from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Chicago Midway Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/13
Fri 3/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chicago