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Cheap flights from Panama City to Chicago from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Chicago departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:20 pm - 10:07 pmPTY-MDW
7h 47m1 stop
Delta Logo
6:00 am - 1:55 pmMDW-PTY
6h 55m1 stop
$587Delta
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Wed, Jan 14 - Tue, Jan 27
Delta Logo
3:20 pm - 10:22 pmPTY-MDW
8h 02m1 stop
Delta Logo
6:00 am - 1:55 pmMDW-PTY
6h 55m1 stop
$596Delta
Find Deal
Thu, Feb 5 - Mon, Feb 9
Delta Logo
3:20 pm - 5:55 pmPTY-MDW
27h 35m2 stops
Delta Logo
1:26 pm - 1:55 pmMDW-PTY
23h 29m2 stops
$601Delta
Find Deal
Thu, Feb 5 - Mon, Feb 9
Delta Logo
8:00 am - 10:22 pmPTY-MDW
15h 22m1 stop
Delta Logo
6:00 am - 1:57 pmMDW-PTY
6h 57m1 stop
$623Delta
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Tue, Dec 23 - Fri, Jan 2
Delta Logo
3:22 pm - 10:22 pmPTY-MDW
8h 00m1 stop
Delta Logo
9:50 am - 8:00 pmMDW-PTY
9h 10m1 stop
$661Delta
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Tue, Dec 23 - Fri, Jan 2
Multiple Airlines Logo
9:33 pm - 7:09 pmPTY-MDW
22h 36m1 stop
Multiple Airlines Logo
10:48 am - 1:00 amMDW-PTY
13h 12m2 stops
$667Multiple Airlines
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Wed, Jan 14 - Tue, Jan 27
Delta Logo
8:05 am - 4:18 pmPTY-MDW
9h 13m1 stop
Delta Logo
6:00 am - 1:57 pmMDW-PTY
6h 57m1 stop
$707Delta
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Sun, Dec 14 - Sat, Jan 3
Multiple Airlines Logo
10:25 am - 6:25 pmPTY-MDW
9h 00m1 stop
Multiple Airlines Logo
10:48 am - 12:40 amMDW-PTY
12h 52m2 stops
$736Multiple Airlines
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Mon, Jan 19 - Fri, Jan 23
Delta Logo
3:46 pm - 11:47 pmPTY-MDW
9h 01m1 stop
Delta Logo
6:00 am - 2:21 pmMDW-PTY
7h 21m1 stop
$745Delta
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Tue, Dec 9 - Mon, Dec 15
Delta Logo
8:00 am - 10:22 pmPTY-MDW
15h 22m1 stop
Delta Logo
6:00 am - 1:55 pmMDW-PTY
6h 55m1 stop
$757Delta
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Tue, Dec 30 - Thu, Jan 29

Delta flights from Panama City to Chicago Midway Airport

Our best Delta deals on Panama City to Chicago Midway Airport flight tickets
Delta
Jan 14
PTY3:20 pmPanama City Tocumen Intl
7h 47m
1 stop
MDW10:07 pmChicago Midway
Jan 27
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
$587
Find similar
Delta
Feb 5
PTY3:20 pmPanama City Tocumen Intl
8h 02m
1 stop
MDW10:22 pmChicago Midway
Feb 9
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
$596
Find similar
Delta
Feb 5
PTY3:20 pmPanama City Tocumen Intl
27h 35m
2 stops
MDW5:55 pmChicago Midway
Feb 9
MDW1:26 pmChicago Midway
23h 29m
2 stops
PTY1:55 pmPanama City Tocumen Intl
$601
Find similar

WestJet flights from Panama City to Chicago Midway Airport

Our best WestJet deals on Panama City to Chicago Midway Airport flight tickets
WestJet
Apr 2
PTY9:20 amPanama City Tocumen Intl
48h 35m
2 stops
MDW9:55 amChicago Midway
Apr 9
MDW10:49 amChicago Midway
45h 31m
2 stops
PTY8:20 amPanama City Tocumen Intl
$1,905
Find similar
WestJet
Dec 23
PTY10:20 amPanama City Tocumen Intl
31h 59m
2 stops
MDW5:19 pmChicago Midway
Jan 14
MDW9:50 amChicago Midway
22h 30m
2 stops
PTY9:20 amPanama City Tocumen Intl
$2,098
Find similar
WestJet
Jan 10
PTY10:20 amPanama City Tocumen Intl
49h 07m
2 stops
MDW10:27 amChicago Midway
Jan 17
MDW11:45 amChicago Midway
20h 35m
2 stops
PTY9:20 amPanama City Tocumen Intl
$2,132
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Panama City to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 1/14

3:20 pm-10:07 pm

1 stop7h 47m

Chicago Midway

Tue 1/27

6:00 am-1:55 pm

1 stop6h 55m

$587

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 2/5

3:20 pm-10:22 pm

1 stop8h 02m

Chicago Midway

Mon 2/9

6:00 am-1:55 pm

1 stop6h 55m

$596

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 2/5

3:20 pm-5:55 pm

2 stops27h 35m

Chicago Midway

Mon 2/9

1:26 pm-1:55 pm

2 stops23h 29m

$601

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 12/23

8:00 am-10:22 pm

1 stop15h 22m

Chicago Midway

Fri 1/2

6:00 am-1:57 pm

1 stop6h 57m

$623

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 12/23

3:22 pm-10:22 pm

1 stop8h 00m

Chicago Midway

Fri 1/2

9:50 am-8:00 pm

1 stop9h 10m

$661

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 1/14

9:33 pm-7:09 pm

1 stop22h 36m

Chicago Midway

Tue 1/27

10:48 am-1:00 am

2 stops13h 12m

$667

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sun 12/14

8:05 am-4:18 pm

1 stop9h 13m

Chicago Midway

Sat 1/3

6:00 am-1:57 pm

1 stop6h 57m

$707

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Mon 1/19

10:25 am-6:25 pm

1 stop9h 00m

Chicago Midway

Fri 1/23

10:48 am-12:40 am

2 stops12h 52m

$736

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 12/9

3:46 pm-11:47 pm

1 stop9h 01m

Chicago Midway

Mon 12/15

6:00 am-2:21 pm

1 stop7h 21m

$745

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 12/30

8:00 am-10:22 pm

1 stop15h 22m

Chicago Midway

Thu 1/29

6:00 am-1:55 pm

1 stop6h 55m

$757

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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When to book flights from Panama City to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Chicago Midway Airport (PTY to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Chicago Midway Airport

Fastest flight time

7h 47m

Direct flights

None
The fastest flight from Panama City to Chicago Midway Airport takes 7h 47m
There are no direct flights from Panama City to Chicago Midway Airport. There are no popular flight routes from Panama City to Chicago Midway Airport.
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  • How far is Panama City Tocumen Intl to Chicago Midway by plane?

    There are 2319.5 mi between Panama City Tocumen Intl and Chicago Midway. A reasonable flight in good conditions will take 7h 47m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Chicago Midway Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Chicago Midway Airport were last updated today.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The necessary travel and health documents for your Chicago Midway Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • How do I get Price Alerts for flights from Panama City to Chicago Midway Airport?

    You can take advantage of momondo’s Price Alerts by first searching for your flights to Panama City from Chicago Midway Airport. Flight offers will be shown to you in real-time. From there you can create a Price Alert by using our on-site widget.

  • How can I save money on flights from Panama City to Chicago Midway Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Crown Point
Munster
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

Finding the right flight to Chicago from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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