Cheap flights from Panama City to Mexico City from $182

The cheapest month to fly to Mexico City Benito Juarez Airport from Panama City is in December. Flight prices, which tend to average around $350, are often lower during this time because this is during the off-season. If you don’t want to visit Mexico City Benito Juarez Airport in December, then you should wait until January to fly from Panama City, when ticket prices are also cheap, with an average price of $352.

The cheapest day to depart from Panama City to Mexico City Benito Juarez Airport is on a Tuesday. Travelers who choose to depart for Mexico City Benito Juarez Airport on a Tuesday will often find tickets for as low as $407. Flights from Panama City to Mexico City Benito Juarez Airport on a Wednesday will generally be more expensive and average around $461. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Mexico City Benito Juarez Airport is at noon. momondo users have found flights departing from Panama City to Mexico City Benito Juarez Airport at noon for as low as $413. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Mexico City Benito Juarez Airport, so prices are often more expensive at around $460 per ticket.

Fly from Panama City Tocumen Intl to Mexico City Benito Juarez for the best Panama City Tocumen Intl - Mexico City Benito Juarez flight prices

You are more likely to see cheaper flights to Mexico City Benito Juarez Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City Benito Juarez Airport for around $406 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City Benito Juarez Airport from Panama City for as low as $366 on momondo.

There are 3 cabin classes available to choose from on Panama City to Mexico City Benito Juarez Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Panama City to Mexico City Benito Juarez Airport.

As of October 2026, prices for Panama City to Mexico City Benito Juarez Airport flights are approximately 15% cheaper when compared to flights at the same time last year.

Copa Airlines is the most popular carrier operating from Panama City Tocumen Intl to Mexico City Benito Juarez

Copa Airlines, Aeromexico and Avianca are the top three most popular airlines that fly to Mexico City Benito Juarez Airport from Panama City according to our data. Copa Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Mexico City Benito Juarez Airport. Keep in mind that there are 3 different airlines that fly to Mexico City Benito Juarez Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 4% of flights between Panama City and Mexico City have experienced a delay on any given week. The average delay length over the past 12 months has been 122 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 4% of their flights experiencing any sort of delay.

Bogotá (BOG) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Flights via San Salvador (SAL) offer the lowest average round-trip price of $293.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 6h 25m.

San Salvador (SAL) has the shortest average layover time for this route: 1h 45m.

As of October 2026, there are 8 flights per day flying from Panama City to Mexico City Benito Juarez Airport. The most common time of day flights depart is 9:00AM, with 46% of flights taking off at noon.

58 flights are operational weekly from Panama City to Mexico City Benito Juarez Airport as of October 2026. The most popular departure day for this route is Fri, with 19% of flights per week taking off on this day.