Cheap flights from Panama City to Mexico City from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Mexico City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 pm - 3:00 am
PTY
-
MEX
13h 05m
1 stop
Avianca Logo
4:50 pm - 10:30 am
MEX
-
PTY
16h 40m
1 stop
$322Avianca
vie., feb. 27 - dom., mar. 1
Avianca Logo
7:50 pm - 1:15 am
PTY
-
MEX
6h 25m
1 stop
Avianca Logo
5:00 am - 4:55 pm
MEX
-
PTY
10h 55m
1 stop
$324Avianca
vie., feb. 13 - vie., feb. 20
Aeromexico Logo
2:46 pm - 5:45 pm
PTY
-
MEX
3h 59mnonstop
Aeromexico Logo
8:55 am - 1:45 pm
MEX
-
PTY
3h 50mnonstop
$335Aeromexico
jue., mar. 5 - jue., mar. 12
Avianca Logo
7:50 pm - 11:20 am
PTY
-
MEX
16h 30m
1 stop
Avianca Logo
12:40 am - 2:00 pm
MEX
-
PTY
12h 20m
1 stop
$341Avianca
sáb., feb. 14 - lun., feb. 16
Avianca Logo
7:50 pm - 11:20 am
PTY
-
MEX
16h 30m
1 stop
Avianca Logo
1:50 pm - 8:50 am
MEX
-
PTY
18h 00m
1 stop
$350Avianca
sáb., feb. 14 - mié., feb. 18
Copa Airlines Logo
7:02 pm - 10:05 pm
PTY
-
MEX
4h 03mnonstop
Copa Airlines Logo
9:50 am - 2:30 pm
MEX
-
PTY
3h 40mnonstop
$352Copa Airlines
mar., feb. 24 - sáb., may. 16
Avianca Logo
5:50 pm - 3:00 am
PTY
-
MEX
10h 10m
1 stop
Avianca Logo
5:00 am - 4:55 pm
MEX
-
PTY
10h 55m
1 stop
$353Avianca
sáb., mar. 14 - dom., mar. 22
Aeromexico Logo
3:00 pm - 6:00 pm
PTY
-
MEX
4h 00mnonstop
Aeromexico Logo
9:00 am - 2:00 pm
MEX
-
PTY
4h 00mnonstop
$355Aeromexico
sáb., may. 30 - sáb., jun. 6
Avianca Logo
5:50 pm - 3:00 am
PTY
-
MEX
10h 10m
1 stop
Avianca Logo
5:00 am - 2:00 pm
MEX
-
PTY
8h 00m
1 stop
$358Avianca
vie., feb. 27 - dom., mar. 1
Avianca Logo
7:50 pm - 1:15 am
PTY
-
MEX
6h 25m
1 stop
Avianca Logo
5:00 am - 2:00 pm
MEX
-
PTY
8h 00m
1 stop
$367Avianca
lun., mar. 16 - dom., mar. 22

Avianca flights from Panama City to Mexico City

Our best Avianca deals on Panama City to Mexico City flight tickets
Avianca
Feb 27
PTY2:55 pmPanama City Tocumen Intl
13h 05m
1 stop
MEX3:00 amMexico City Benito Juarez
Mar 1
MEX4:50 pmMexico City Benito Juarez
16h 40m
1 stop
PTY10:30 amPanama City Tocumen Intl
$322
Avianca
Feb 13
PTY7:50 pmPanama City Tocumen Intl
6h 25m
1 stop
MEX1:15 amMexico City Benito Juarez
Feb 20
MEX5:00 amMexico City Benito Juarez
10h 55m
1 stop
PTY4:55 pmPanama City Tocumen Intl
$324
Avianca
Feb 14
PTY7:50 pmPanama City Tocumen Intl
16h 30m
1 stop
MEX11:20 amMexico City Benito Juarez
Feb 16
MEX12:40 amMexico City Benito Juarez
12h 20m
1 stop
PTY2:00 pmPanama City Tocumen Intl
$341

Copa Airlines flights from Panama City to Mexico City

Our best Copa Airlines deals on Panama City to Mexico City flight tickets
Copa Airlines
Feb 24
PTY4:17 pmPanama City Tocumen Intl
4h 03m
MEX7:20 pmMexico City Benito Juarez
May 23
MEX1:10 pmMexico City Benito Juarez
3h 40m
PTY5:50 pmPanama City Tocumen Intl
$352
Copa Airlines
Feb 4
PTY4:17 pmPanama City Tocumen Intl
4h 03m
MEX7:20 pmMexico City Benito Juarez
Feb 11
MEX3:30 pmMexico City Benito Juarez
3h 37m
PTY8:07 pmPanama City Tocumen Intl
$374
Copa Airlines
Feb 12
PTY9:25 pmPanama City Tocumen Intl
3h 50m
MEX12:15 amMexico City Benito Juarez
Feb 18
MEX9:25 amMexico City Benito Juarez
3h 41m
PTY2:06 pmPanama City Tocumen Intl
$395

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated febrero 2, 2026.
Use the filters below to find and compare flights from Panama City to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

vie. 2/27

2:55 pm-3:00 am

1 stop13h 05m

Mexico City Benito Juarez

dom. 3/1

4:50 pm-10:30 am

1 stop16h 40m

$322

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

vie. 2/13

7:50 pm-1:15 am

1 stop6h 25m

Mexico City Benito Juarez

vie. 2/20

5:00 am-4:55 pm

1 stop10h 55m

$324

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

jue. 3/5

2:46 pm-5:45 pm

Nonstop3h 59m

Mexico City Benito Juarez

jue. 3/12

8:55 am-1:45 pm

Nonstop3h 50m

$335

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

sáb. 2/14

7:50 pm-11:20 am

1 stop16h 30m

Mexico City Benito Juarez

lun. 2/16

12:40 am-2:00 pm

1 stop12h 20m

$341

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

sáb. 2/14

7:50 pm-11:20 am

1 stop16h 30m

Mexico City Benito Juarez

mié. 2/18

1:50 pm-8:50 am

1 stop18h 00m

$350

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

mar. 2/24

7:02 pm-10:05 pm

Nonstop4h 03m

Mexico City Benito Juarez

sáb. 5/16

9:50 am-2:30 pm

Nonstop3h 40m

$352

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

sáb. 3/14

5:50 pm-3:00 am

1 stop10h 10m

Mexico City Benito Juarez

dom. 3/22

5:00 am-4:55 pm

1 stop10h 55m

$353

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

sáb. 5/30

3:00 pm-6:00 pm

Nonstop4h 00m

Mexico City Benito Juarez

sáb. 6/6

9:00 am-2:00 pm

Nonstop4h 00m

$355

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

vie. 2/27

5:50 pm-3:00 am

1 stop10h 10m

Mexico City Benito Juarez

dom. 3/1

5:00 am-2:00 pm

1 stop8h 00m

$358

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

lun. 3/16

7:50 pm-1:15 am

1 stop6h 25m

Mexico City Benito Juarez

dom. 3/22

5:00 am-2:00 pm

1 stop8h 00m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Panama City to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Panama City is in July. Flight prices, which tend to average around $342, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of July, then book flights to Mexico City from Panama City during December instead. Flights to Mexico City in December, while not as cheap as those in July, still average around $342.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Thursday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $401. On the other hand, Saturday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $459.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is at noon. momondo users have found flights departing from Panama City to Mexico City at noon for as low as $377. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Mexico City, so prices are often more expensive at around $642 per ticket.

What is the cheapest Panama City Tocumen Intl to Mexico City Benito Juarez flight route?

Fly from Panama City Tocumen Intl to Mexico City Benito Juarez for the best Panama City Tocumen Intl - Mexico City Benito Juarez flight prices

How far in advance should I book a flight to Mexico City?

You are more likely to see cheaper flights to Mexico City from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City from Panama City for as low as $343 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Mexico City Benito Juarez flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Mexico City Benito Juarez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Mexico City flights?

No. A direct flight is the cheapest option for a flight between Panama City to Mexico City.

How have Panama City to Mexico City flight prices changed over time?

As of February 2026, prices for Panama City to Mexico City flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Mexico City (PTY to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Mexico City

Best Price Found

$388

Fastest flight time

3h 38m

Direct flights

Every day

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Panama City in the past 72 hours is $388. The best round-trip flight deal from Panama City to Mexico City found on momondo in the last 72 hours is $356.
The fastest flight from Panama City to Mexico City takes 3h 38m
Direct flights go from Panama City to Mexico City every day.
There is 1 airport in Mexico City. From Panama City there are direct flights to Mexico City Benito Juarez (MEX).
  • How far is Panama City Tocumen Intl to Mexico City Benito Juarez by plane?

    Mexico City Benito Juarez is 1496.2 mi away from Panama City Tocumen Intl. 3h 38m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The necessary travel and health documents for your Mexico City Benito Juarez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Mexico City?

  • What is the most popular airline from Panama City to Mexico City?

Best airlines flying from Panama City to Mexico City

Compare and see reviews for airlines that fly from Panama City to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
AeromexicoPriceFrom $183Free CancellationRating
7.4
1,583 reviews
Search Aeromexico flights
Copa AirlinesPriceFrom $201Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
AviancaPriceFrom $214Free CancellationRating
6.6
2,492 reviews
Search Avianca flights
  • Copa Airlines Flights From Panama City to Mexico City

    The lowest priced Copa Airlines flight from Panama City to Mexico City from the last 72 hours was $201. Generally, Copa Airlines has 35 flights on this route every week with an average price of $415. Copa Airlines is rated 7.5/10 by our users.

  • Aeromexico Flights From Panama City to Mexico City

    $183 is the best Aeromexico flight deal from Panama City to Mexico City found on momondo over the last 72 hours. The average Aeromexico ticket price found was closer to $344, however, with flight time and availability significantly affecting the price. Aeromexico (7.4/10 from 1,583 user reviews) flies into Mexico City from Panama City 6 times in an average week so prices can vary.

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Mexico City?

Finding the right flight to Mexico City from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City quick and easy, saving you time and money.

Can I find flights from Panama City to Mexico City with flexible booking policies on momondo?

All flight searches from Panama City to Mexico City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Mexico City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Mexico City.

I’m not ready to book a flight from Panama City to Mexico City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Mexico City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
mié. 3/4
mié. 3/11

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Airports servicing Mexico City Federal District