Cheap flights from Panama City to London from $541

The cheapest month to fly to London from Panama City is in May. Flight prices, which tend to average around $866, are often lower during this time because this is during the off-season. The month of March is another great option to travel to London, with average flight prices from Panama City averaging around $889.

You are more likely to see cheaper flights to London from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to London for around $1,101 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to London from Panama City for as low as $847 on momondo.

You could potentially save up to 18% on your flight if you consider stops on a Panama City to London flight.

As of March 2026, prices for Panama City to London flights are approximately 12% more expensive when compared to flights at the same time last year.

Avianca, Air Europa, and Turkish Airlines are the most popular carriers operating from Panama City Tocumen Intl to London

United Airlines, Air France and Avianca are the top three most popular airlines that fly to London from Panama City according to our data. United Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to London. Keep in mind that there are 4 different airlines that fly to London on a routine basis, so you have a few additional options to choose from.

Newark (EWR) was the most common stop: 36% of momondo users choosing 1-stop flights on this route connected there.

Flights via Istanbul (IST) offer the lowest average round-trip price of $842.

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 00m.

Atlanta (ATL) has the shortest average layover time for this route: 1h 37m.