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Cheap flights from Panama City to Madrid from $435

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 9/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Avianca Logo
1:30 pm - 2:05 pmPTY-MAD
17h 35m2 stops
Avianca Logo
1:30 am - 2:40 pmMAD-PTY
20h 10m2 stops
$555Avianca
Find Deal
Thu, Jul 3 - Wed, Aug 20
Avianca Logo
1:30 pm - 1:25 pmPTY-MAD
17h 55m2 stops
Avianca Logo
12:35 am - 12:35 pmMAD-PTY
18h 00m2 stops
$691Avianca
Find Deal
Tue, Nov 11 - Mon, Nov 24
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
$706Air Europa
Find Deal
Tue, Oct 21 - Wed, Nov 5
Air France Logo
7:55 pm - 7:20 pmPTY-MAD
16h 25m1 stop
Air France Logo
6:00 am - 5:45 pmMAD-PTY
18h 45m1 stop
$716Air France
Find Deal
Thu, Jul 3 - Thu, Aug 21
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$724Air Europa
Find Deal
Sun, Aug 3 - Sun, Aug 24
Air France Logo
7:55 pm - 7:20 pmPTY-MAD
16h 25m1 stop
Air France Logo
10:05 am - 5:45 pmMAD-PTY
14h 40m1 stop
$768Air France
Find Deal
Thu, Oct 2 - Tue, Oct 14
Iberia Logo
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
Iberia Logo
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
$778Iberia
Find Deal
Mon, Nov 3 - Sat, Nov 15
Iberia Logo
5:10 pm - 10:15 amPTY-MAD
10h 05mnonstop
Iberia Logo
12:00 pm - 3:40 pmMAD-PTY
10h 40mnonstop
$786Iberia
Find Deal
Thu, Jul 3 - Thu, Aug 21
United Airlines Logo
10:55 pm - 6:40 amPTY-MAD
24h 45m2 stops
United Airlines Logo
10:50 am - 7:31 pmMAD-PTY
15h 41m1 stop
$846United Airlines
Find Deal
Thu, Jul 10 - Wed, Jul 23
United Airlines Logo
9:45 am - 9:00 amPTY-MAD
16h 15m1 stop
United Airlines Logo
11:15 am - 2:14 pmMAD-PTY
33h 59m2 stops
$848United Airlines
Find Deal
Sun, Oct 5 - Wed, Oct 15

Avianca flights from Panama City to Madrid

Our best Avianca deals on Panama City to Madrid flight tickets
Avianca
Jul 3
PTY1:30 pmPanama City Tocumen Intl
17h 35m
2 stops
MAD2:05 pmMadrid Barajas
Aug 20
MAD1:30 amMadrid Barajas
20h 10m
2 stops
PTY2:40 pmPanama City Tocumen Intl
Avianca
Nov 11
PTY1:30 pmPanama City Tocumen Intl
17h 55m
2 stops
MAD1:25 pmMadrid Barajas
Nov 24
MAD12:35 amMadrid Barajas
18h 00m
2 stops
PTY12:35 pmPanama City Tocumen Intl
Avianca
Jul 3
PTY1:30 pmPanama City Tocumen Intl
17h 35m
2 stops
MAD2:05 pmMadrid Barajas
Aug 21
MAD11:25 amMadrid Barajas
19h 45m
2 stops
PTY12:10 amPanama City Tocumen Intl

Air Europa flights from Panama City to Madrid

Our best Air Europa deals on Panama City to Madrid flight tickets
Air Europa
Oct 21
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Nov 5
MAD3:10 pmMadrid Barajas
10h 35m
PTY7:45 pmPanama City Tocumen Intl
Air Europa
Aug 3
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Aug 24
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl
Air Europa
Jul 10
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Aug 21
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl

See travel insights to Madrid from

How to get the cheapest flight ticket from Panama City to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of March is, on average, the cheapest month to fly to Madrid from Panama City, with most prices found around $685. If you don’t want to visit Madrid in March, then you should wait until February to fly from Panama City, when ticket prices are also cheap, with an average price of $694.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Tuesday when prices can be found for as low as $820. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Saturday is $862.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Panama City in the morning is the least expensive time of day to depart. momondo users have found prices as low as $751 when looking at flights departing in the morning. Flights to Madrid are more costly at noon, with an average ticket price of $920. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Panama City Tocumen Intl to Madrid Barajas flight route?

Fly from Panama City Tocumen Intl to Madrid Barajas for the best Panama City Tocumen Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

You are more likely to see cheaper flights to Madrid from Panama City when booking 17 weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $772 when searching 17 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Panama City for as low as $721 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Madrid Barajas flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Madrid flights?

You could potentially save up to 19% on your flight if you consider stops on a Panama City to Madrid flight.

How have Panama City to Madrid flight prices changed over time?

As of June 2025, prices for Panama City to Madrid flights are approximately 7% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Madrid (PTY to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Madrid

Best Price Found

$435

Fastest flight time

9h 35m

Direct flights

Every day

Airports in Madrid

1 airport
The best one-way flight to Madrid from Panama City in the past 72 hours is $435. The best round-trip flight deal from Panama City to Madrid found on momondo in the last 72 hours is $555.
The fastest flight from Panama City to Madrid takes 9h 35m
Direct flights go from Panama City to Madrid every day.
There is 1 airport near Madrid: Madrid Barajas (MAD)

  • How far is Panama City Tocumen Intl to Madrid Barajas by plane?

    The distance between Panama City Tocumen Intl and Madrid Barajas is about 5069.0 mi. Typically, this will take 9h 35m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The necessary travel and health documents for your Madrid Barajas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Madrid?

  • What is the most popular airline from Panama City to Madrid?


Best airlines flying from Panama City to Madrid

Compare and see reviews for airlines that fly from Panama City to Madrid with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $543Free CancellationRating
6.7
2,345 reviews
Search Avianca flights
Air EuropaPriceFrom $666Free CancellationRating
6.9
529 reviews
Search Air Europa flights
KLMPriceFrom $670Free CancellationRating
7.8
1,358 reviews
Search KLM flights
United AirlinesPriceFrom $678Free CancellationRating
7.4
8,790 reviews
Search United Airlines flights
IberiaPriceFrom $680Free CancellationRating
7.0
2,776 reviews
Search Iberia flights
Air FrancePriceFrom $681Free CancellationRating
7.5
1,463 reviews
Search Air France flights
Turkish AirlinesPriceFrom $729Free CancellationRating
7.3
3,848 reviews
Search Turkish Airlines flights
  • Iberia Flights From Panama City to Madrid

    Across 2 Iberia flights from Panama City to Madrid this week, the average price was $831, with the best Iberia deals starting from $680 round-trip. 2,776 users have rated Iberia on momondo, with an average score of 7.0/10.

  • Air Europa Flights From Panama City to Madrid

    Another popular option for Panama City to Madrid flights is Air Europa (6.9/10, 529 ratings). Air Europa flies from Panama City to Madrid around 5 times per week, with deals starting from $666 round-trip and rising to an average price of around $785.


Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Getafe
Segovia
Fuenlabrada
San Lorenzo de El Escorial
Guadalajara
El Arenal

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Madrid?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Madrid. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Madrid with flexible booking policies on momondo?

Flights from Panama City to Madrid with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Madrid?

momondo helps you find the best flight between Panama City and Madrid by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Madrid right now. Can momondo alert me if prices change?

Price alerts on flights to Madrid from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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1 adult
Tue 6/17
Tue 6/24

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