How many flights depart from Panama City to Madrid on average per week?

50 flights are operational weekly from Panama City to Madrid as of September 2025. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

What is the cheapest airline that flies from Panama City Tocumen Intl to Madrid Barajas?

KLM, Air France, and Air Europa are the most popular carriers operating from Panama City Tocumen Intl to Madrid Barajas

Which layover airport offers the lowest fares from Panama City to Madrid?

Flights via Paris (CDG) offer the lowest average round-trip price of $701.

What airlines fly to Madrid?

Air Europa, Iberia and Avianca are the top three most popular airlines that fly to Madrid from Panama City according to our data. Air Europa is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Madrid. Keep in mind that there are 8 different airlines that fly to Madrid on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Panama City to Madrid?

Flights connecting via Bogotá (BOG) have the shortest average one-way travel time: 13h 56m.

How many flights depart from Panama City to Madrid on average per day?

As of September 2025, there are 7 flights per day flying from Panama City to Madrid. The most common time of day flights depart is 8:00PM, with 70% of flights taking off in the evening.

Which layover airport has the shortest connection time from Panama City to Madrid?

Bogotá (BOG) has the shortest average layover time for this route: 2h 12m.

Which airport is the most popular layover for flights between Panama City and Madrid?

Bogotá (BOG) was the most common stop: 55% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

Prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport were last updated today.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

As of September 2025, there are 8 operators available to choose from for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Madrid Barajas Airport.

What documentation or ID do you need to fly to Madrid Barajas Airport?

The necessary travel and health documents for your Madrid Barajas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$502 Cheap Flights from Panama City to Madrid in 2025/26

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Round-trip

One-way

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Direct

Cheap round-trip flights

9:30 pm - 1:05 pmPTY-MAD

9h 35mnonstop

3:10 pm - 7:45 pmMAD-PTY

10h 35mnonstop

$677Air Europa

Find Deal

Sun, Nov 2 - Sat, Nov 15

9:30 pm - 1:05 pmPTY-MAD

9h 35mnonstop

3:10 pm - 7:45 pmMAD-PTY

10h 35mnonstop

$681Air Europa

Find Deal

Tue, Dec 2 - Fri, Dec 12

9:30 pm - 1:05 pmPTY-MAD

9h 35mnonstop

3:10 pm - 7:45 pmMAD-PTY

10h 35mnonstop

$683Air Europa

Find Deal

Wed, Feb 4 - Wed, Feb 18

2:55 am - 11:20 pmPTY-MAD

14h 25m1 stop

1:20 am - 4:55 pmMAD-PTY

21h 35m1 stop

$687Avianca

Find Deal

Tue, Feb 3 - Fri, Feb 20

2:55 am - 8:50 amPTY-MAD

23h 55m1 stop

4:20 pm - 1:00 amMAD-PTY

14h 40m1 stop

$691Avianca

Find Deal

Mon, Oct 27 - Tue, Nov 4

6:20 pm - 10:25 amPTY-MAD

10h 05mnonstop

11:40 am - 4:45 pmMAD-PTY

11h 05mnonstop

$692Iberia

Find Deal

Mon, Nov 10 - Wed, Nov 19

5:10 pm - 10:15 amPTY-MAD

10h 05mnonstop

11:40 am - 4:45 pmMAD-PTY

11h 05mnonstop

$717Iberia

Find Deal

Mon, Oct 20 - Wed, Feb 18

10:20 pm - 5:40 pmPTY-MAD

13h 20m1 stop

10:00 am - 8:10 pmMAD-PTY

16h 10m1 stop

$718Air France

Find Deal

Fri, Nov 14 - Sun, Nov 23

9:55 pm - 4:50 pmPTY-MAD

35h 55m1 stop

6:20 pm - 8:00 pmMAD-PTY

32h 40m1 stop

$719Turkish Airlines

Find Deal

Wed, Oct 8 - Sat, Oct 18

9:45 pm - 1:20 pmPTY-MAD

33h 35m1 stop

11:55 am - 7:50 pmMAD-PTY

37h 55m1 stop

$745Turkish Airlines

Find Deal

Sat, Nov 15 - Sun, Nov 23

Air Europa flights from Panama City to Madrid

Our best Air Europa deals on Panama City to Madrid flight tickets

Air Europa

Nov 2

PTY9:30 pmPanama City Tocumen Intl

9h 35m

MAD1:05 pmMadrid Barajas

Nov 15

MAD3:10 pmMadrid Barajas

10h 35m

PTY7:45 pmPanama City Tocumen Intl

$677

Find similar

Air Europa

Dec 2

PTY9:30 pmPanama City Tocumen Intl

9h 35m

MAD1:05 pmMadrid Barajas

Dec 12

MAD3:10 pmMadrid Barajas

10h 35m

PTY7:45 pmPanama City Tocumen Intl

$681

Find similar

Air Europa

Feb 4

PTY9:30 pmPanama City Tocumen Intl

9h 35m

MAD1:05 pmMadrid Barajas

Feb 18

MAD3:10 pmMadrid Barajas

10h 35m

PTY7:45 pmPanama City Tocumen Intl

$683

Find similar

Avianca flights from Panama City to Madrid

Our best Avianca deals on Panama City to Madrid flight tickets

Avianca

Feb 3

PTY2:55 amPanama City Tocumen Intl

14h 25m

1 stop

MAD11:20 pmMadrid Barajas

Feb 20

MAD1:20 amMadrid Barajas

21h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

$687

Find similar

Avianca

Oct 27

PTY2:55 amPanama City Tocumen Intl

23h 55m

1 stop

MAD8:50 amMadrid Barajas

Nov 4

MAD4:20 pmMadrid Barajas

14h 40m

1 stop

PTY1:00 amPanama City Tocumen Intl

$691

Find similar

Avianca

Nov 13

PTY2:55 amPanama City Tocumen Intl

14h 25m

1 stop

MAD11:20 pmMadrid Barajas

Nov 23

MAD4:20 pmMadrid Barajas

14h 40m

1 stop

PTY1:00 amPanama City Tocumen Intl

$698

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 11/2

9:30 pm-1:05 pm

Nonstop9h 35m

Madrid Barajas

Sat 11/15

3:10 pm-7:45 pm

Nonstop10h 35m

$677

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 12/2

9:30 pm-1:05 pm

Nonstop9h 35m

Madrid Barajas

Fri 12/12

3:10 pm-7:45 pm

Nonstop10h 35m

$681

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 2/4

9:30 pm-1:05 pm

Nonstop9h 35m

Madrid Barajas

Wed 2/18

3:10 pm-7:45 pm

Nonstop10h 35m

$683

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 2/3

2:55 am-11:20 pm

1 stop14h 25m

Madrid Barajas

Fri 2/20

1:20 am-4:55 pm

1 stop21h 35m

$687

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 10/27

2:55 am-8:50 am

1 stop23h 55m

Madrid Barajas

Tue 11/4

4:20 pm-1:00 am

1 stop14h 40m

$691

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 11/10

6:20 pm-10:25 am

Nonstop10h 05m

Madrid Barajas

Wed 11/19

11:40 am-4:45 pm

Nonstop11h 05m

$692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 10/20

5:10 pm-10:15 am

Nonstop10h 05m

Madrid Barajas

Wed 2/18

11:40 am-4:45 pm

Nonstop11h 05m

$717

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 11/14

10:20 pm-5:40 pm

1 stop13h 20m

Madrid Barajas

Sun 11/23

10:00 am-8:10 pm

1 stop16h 10m

$718

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 10/8

9:55 pm-4:50 pm

1 stop35h 55m

Madrid Barajas

Sat 10/18

6:20 pm-8:00 pm

1 stop32h 40m

$719

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 11/15

9:45 pm-1:20 pm

1 stop33h 35m

Madrid Barajas

Sun 11/23

11:55 am-7:50 pm

1 stop37h 55m

$745

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Panama City to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to Madrid?

The month of March is, on average, the cheapest month to fly to Madrid from Panama City, with most prices found around $696. If you don’t want to visit Madrid in March, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $703.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Tuesday when prices can be found for as low as $836. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Saturday is $875.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Panama City in the morning is the least expensive time of day to depart. momondo users have found prices as low as $751 when looking at flights departing in the morning. Flights to Madrid are more costly at noon, with an average ticket price of $920. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Panama City Tocumen Intl to Madrid Barajas flight route?

Fly from Panama City Tocumen Intl to Madrid Barajas for the best Panama City Tocumen Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

You are more likely to see cheaper flights to Madrid from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $776 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Panama City for as low as $723 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Madrid Barajas flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Madrid flights?

No. A direct flight is the cheapest option for a flight between Panama City to Madrid.

How have Panama City to Madrid flight prices changed over time?

As of September 2025, prices for Panama City to Madrid flights are approximately 23% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Madrid according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Madrid (PTY to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Madrid

Best Price Found	$524
Fastest flight time	9h 35m
Direct flights	Every day
Airports in Madrid	1 airport

The best one-way flight to Madrid from Panama City in the past 72 hours is $524. The best round-trip flight deal from Panama City to Madrid found on momondo in the last 72 hours is $773.

The fastest flight from Panama City to Madrid takes 9h 35m

Direct flights go from Panama City to Madrid every day.

There is 1 airport near Madrid: Madrid Barajas (MAD)

Search flight deals

How far is Panama City Tocumen Intl to Madrid Barajas by plane?
The distance between Panama City Tocumen Intl and Madrid Barajas is about 5069.0 mi. Typically, this will take 9h 35m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?
Prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport were last updated today.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?
As of September 2025, there are 8 operators available to choose from for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Madrid Barajas Airport.
What documentation or ID do you need to fly to Madrid Barajas Airport?
The necessary travel and health documents for your Madrid Barajas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Madrid?
Based on momondo bookings for flights between Panama City and Madrid, the leading plane model is Boeing 787-9 Dreamliner, making up 49.09% of the total bookings. Other popular models include Airbus A330-200 with 30.87%, Airbus A330 with 11.91%, and Airbus A330-300 with 2.67%.
What is the most popular airline from Panama City to Madrid?
momondo data reveals that the most frequently booked airline on the route from Panama City to Madrid is Air Europa, representing 50% of all bookings. The subsequent popular airlines are Iberia at 28%, Avianca at 8%, and Air France at 5%.

Best airlines flying from Panama City to Madrid

Compare and see reviews for airlines that fly from Panama City to Madrid with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $604	Free Cancellation	Rating 6.7 2,435 reviews	Search Avianca flights
Air Europa	PriceFrom $662	Free Cancellation	Rating 7.0 556 reviews	Search Air Europa flights
KLM	PriceFrom $681	Free Cancellation	Rating 7.8 1,385 reviews	Search KLM flights
Iberia	PriceFrom $682	Free Cancellation	Rating 7.0 2,924 reviews	Search Iberia flights
Air France	PriceFrom $695	Free Cancellation	Rating 7.4 1,469 reviews	Search Air France flights
Turkish Airlines	PriceFrom $698	Free Cancellation	Rating 7.3 3,968 reviews	Search Turkish Airlines flights
United Airlines	PriceFrom $700	Free Cancellation	Rating 7.4 8,929 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $826	Free Cancellation	Rating 7.6 1,531 reviews	Search Copa Airlines flights

Copa Airlines Flights From Panama City to Madrid
Across 10 Copa Airlines flights from Panama City to Madrid this week, the average price was $1,180, with the best Copa Airlines deals starting from $826 round-trip. 1,531 users have rated Copa Airlines on momondo, with an average score of 7.6/10.
Air Europa Flights From Panama City to Madrid
Another popular option for Panama City to Madrid flights is Air Europa (7.0/10, 556 ratings). Air Europa flies from Panama City to Madrid around 7 times per week, with deals starting from $662 round-trip and rising to an average price of around $792.

Toledo

Segovia

Getafe

Fuenlabrada

San Lorenzo de El Escorial

Guadalajara

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Why should I use momondo to find a flight deal from Panama City to Madrid?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Madrid. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Madrid with flexible booking policies on momondo?

Flights from Panama City to Madrid with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Madrid?

momondo helps you find the best flight between Panama City and Madrid by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Madrid right now. Can momondo alert me if prices change?

Price alerts on flights to Madrid from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to Spain

Cheap flights from Panama City to Madrid from $502

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 10/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Air Europa flights from Panama City to Madrid

Our best Air Europa deals on Panama City to Madrid flight tickets

Avianca flights from Panama City to Madrid

Our best Avianca deals on Panama City to Madrid flight tickets

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How to get the cheapest flight ticket from Panama City to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of March is, on average, the cheapest month to fly to Madrid from Panama City, with most prices found around $696. If you don’t want to visit Madrid in March, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $703.

What is the cheapest day to depart on your flight to Madrid?

What is the cheapest time of day to depart on your flight to Madrid?

What is the cheapest Panama City Tocumen Intl to Madrid Barajas flight route?

Fly from Panama City Tocumen Intl to Madrid Barajas for the best Panama City Tocumen Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

What cabin class options are available on Panama City Tocumen Intl to Madrid Barajas flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Madrid flights?

No. A direct flight is the cheapest option for a flight between Panama City to Madrid.

How have Panama City to Madrid flight prices changed over time?

As of September 2025, prices for Panama City to Madrid flights are approximately 23% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Madrid Barajas?

KLM, Air France, and Air Europa are the most popular carriers operating from Panama City Tocumen Intl to Madrid Barajas

What airlines fly to Madrid?

Which airport is the most popular layover for flights between Panama City and Madrid?

Bogotá (BOG) was the most common stop: 55% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Panama City to Madrid?

Flights via Paris (CDG) offer the lowest average round-trip price of $701.

Which layover airport has the shortest travel time from Panama City to Madrid?

Flights connecting via Bogotá (BOG) have the shortest average one-way travel time: 13h 56m.

Which layover airport has the shortest connection time from Panama City to Madrid?

Bogotá (BOG) has the shortest average layover time for this route: 2h 12m.

How many flights depart from Panama City to Madrid on average per day?

As of September 2025, there are 7 flights per day flying from Panama City to Madrid. The most common time of day flights depart is 8:00PM, with 70% of flights taking off in the evening.

How many flights depart from Panama City to Madrid on average per week?

50 flights are operational weekly from Panama City to Madrid as of September 2025. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

When to book flights from Panama City to Madrid

Cheap Panama City to Madrid (PTY to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Madrid

Best Price Found

Fastest flight time

Direct flights

Airports in Madrid

How far is Panama City Tocumen Intl to Madrid Barajas by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

What documentation or ID do you need to fly to Madrid Barajas Airport?

What is the most popular plane model from Panama City to Madrid?

What is the most popular airline from Panama City to Madrid?

Best airlines flying from Panama City to Madrid

Compare and see reviews for airlines that fly from Panama City to Madrid with momondo

Copa Airlines Flights From Panama City to Madrid

Air Europa Flights From Panama City to Madrid

Traveling to a place near Madrid?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Madrid?

Can I find flights from Panama City to Madrid with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Madrid?

I’m not ready to book a flight from Panama City to Madrid right now. Can momondo alert me if prices change?

An easier way to manage your Madrid trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.