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Cheap flights from Panama City, Florida to Italy from $494

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Italy departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Italy

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:54 pm - 9:25 am
ECP
-
FCO
33h 31m2 stops
United Airlines Logo
12:50 pm - 9:56 pm
FCO
-
ECP
40h 06m2 stops
$494United Airlines
Thu, Feb 5 - Thu, Feb 26
United Airlines Logo
4:54 pm - 8:30 am
ECP
-
FCO
32h 36m2 stops
United Airlines Logo
7:05 am - 12:02 pm
FCO
-
ECP
35h 57m2 stops
$495United Airlines
Mon, Jan 19 - Mon, Jan 26
KLM Logo
7:20 am - 10:30 am
ECP
-
FCO
20h 10m1 stop
KLM Logo
12:00 pm - 10:40 pm
FCO
-
ECP
17h 40m2 stops
$497KLM
Mon, Jan 19 - Mon, Jan 26
KLM Logo
3:45 pm - 10:30 am
ECP
-
FCO
11h 45m1 stop
KLM Logo
12:40 pm - 5:19 pm
FCO
-
ECP
35h 39m1 stop
$498KLM
Thu, Feb 5 - Thu, Feb 26
United Airlines Logo
1:10 pm - 7:55 am
ECP
-
FCO
35h 45m2 stops
United Airlines Logo
12:45 pm - 9:59 pm
FCO
-
ECP
40h 14m2 stops
$500United Airlines
Wed, Feb 4 - Sun, Feb 8
United Airlines Logo
6:30 am - 6:45 am
ECP
-
FCO
17h 15m2 stops
United Airlines Logo
7:05 am - 12:02 pm
FCO
-
ECP
35h 57m2 stops
$509United Airlines
Tue, Feb 3 - Tue, Feb 10
Delta Logo
9:24 am - 9:45 am
ECP
-
FCO
17h 21m2 stops
Delta Logo
12:40 pm - 10:40 pm
FCO
-
ECP
17h 00m1 stop
$511Delta
Tue, Feb 3 - Tue, Feb 10
United Airlines Logo
2:10 pm - 1:25 pm
ECP
-
FCO
17h 15m2 stops
United Airlines Logo
7:05 am - 9:57 pm
FCO
-
ECP
20h 52m2 stops
$513United Airlines
Mon, Mar 9 - Tue, Mar 17
United Airlines Logo
1:10 pm - 7:55 am
ECP
-
FCO
35h 45m2 stops
United Airlines Logo
7:05 am - 9:59 pm
FCO
-
ECP
21h 54m2 stops
$515United Airlines
Wed, Feb 4 - Sun, Feb 8
United Airlines Logo
10:24 am - 11:00 pm
ECP
-
FCO
30h 36m2 stops
United Airlines Logo
12:10 pm - 9:57 pm
FCO
-
ECP
63h 47m3 stops
$521United Airlines
Mon, Mar 9 - Tue, Mar 17

Delta flights from Panama City, Florida to Italy

Our best Delta deals on Panama City, Florida to Italy flight tickets
Delta
Feb 3
ECP9:24 amPanama City NW Florida Beaches
17h 21m
2 stops
FCO9:45 amRome Fiumicino
Feb 10
FCO12:40 pmRome Fiumicino
17h 00m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
$511
Find similar
Delta
Feb 3
ECP12:15 pmPanama City NW Florida Beaches
15h 15m
1 stop
FCO10:30 amRome Fiumicino
Feb 10
FCO12:40 pmRome Fiumicino
17h 00m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
$601
Find similar
Delta
Apr 29
ECP8:15 amPanama City NW Florida Beaches
16h 20m
1 stop
FCO7:35 amRome Fiumicino
Oct 28
FCO6:10 amRome Fiumicino
17h 40m
2 stops
ECP5:50 pmPanama City NW Florida Beaches
$1,103
Find similar

KLM flights from Panama City, Florida to Italy

Our best KLM deals on Panama City, Florida to Italy flight tickets
KLM
Jan 19
ECP7:20 amPanama City NW Florida Beaches
20h 10m
1 stop
FCO10:30 amRome Fiumicino
Jan 26
FCO12:00 pmRome Fiumicino
17h 40m
2 stops
ECP10:40 pmPanama City NW Florida Beaches
$497
Find similar
KLM
Feb 5
ECP3:45 pmPanama City NW Florida Beaches
11h 45m
1 stop
FCO10:30 amRome Fiumicino
Feb 26
FCO12:40 pmRome Fiumicino
35h 39m
1 stop
ECP5:19 pmPanama City NW Florida Beaches
$498
Find similar
KLM
Mar 9
ECP1:30 pmPanama City NW Florida Beaches
13h 40m
2 stops
FCO9:10 amRome Fiumicino
Mar 17
FCO11:40 amRome Fiumicino
26h 59m
1 stop
ECP8:39 amPanama City NW Florida Beaches
$522
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Thu 2/5

4:54 pm-9:25 am

2 stops33h 31m

Rome Fiumicino

Thu 2/26

12:50 pm-9:56 pm

2 stops40h 06m

$494

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 1/19

4:54 pm-8:30 am

2 stops32h 36m

Rome Fiumicino

Mon 1/26

7:05 am-12:02 pm

2 stops35h 57m

$495

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 1/19

7:20 am-10:30 am

1 stop20h 10m

Rome Fiumicino

Mon 1/26

12:00 pm-10:40 pm

2 stops17h 40m

$497

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Thu 2/5

3:45 pm-10:30 am

1 stop11h 45m

Rome Fiumicino

Thu 2/26

12:40 pm-5:19 pm

1 stop35h 39m

$498

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Wed 2/4

1:10 pm-7:55 am

2 stops35h 45m

Rome Fiumicino

Sun 2/8

12:45 pm-9:59 pm

2 stops40h 14m

$500

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 2/3

6:30 am-6:45 am

2 stops17h 15m

Rome Fiumicino

Tue 2/10

7:05 am-12:02 pm

2 stops35h 57m

$509

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 2/3

9:24 am-9:45 am

2 stops17h 21m

Rome Fiumicino

Tue 2/10

12:40 pm-10:40 pm

1 stop17h 00m

$511

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 3/9

2:10 pm-1:25 pm

2 stops17h 15m

Rome Fiumicino

Tue 3/17

7:05 am-9:57 pm

2 stops20h 52m

$513

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Wed 2/4

1:10 pm-7:55 am

2 stops35h 45m

Rome Fiumicino

Sun 2/8

7:05 am-9:59 pm

2 stops21h 54m

$515

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 3/9

10:24 am-11:00 pm

2 stops30h 36m

Rome Fiumicino

Tue 3/17

12:10 pm-9:57 pm

3 stops63h 47m

$521

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Italy from

How to get the cheapest flight ticket from Panama City, Florida to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Italy?

According to our data, Monday is the cheapest day to fly to Italy from Panama City, Florida. The lowest ticket price found for a Monday departure recently was $859. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Panama City, Florida to Italy for around $1,793.

Can stopping save me money on Panama City, Florida to Italy flights?

You could potentially save up to 65% on your flight if you consider stops on a Panama City, Florida to Italy flight.

Cheap Panama City, Florida to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Italy

Fastest flight time

16h 20m

Direct flights

None
The fastest flight from Panama City, Florida to Italy takes 16h 20m
There are no direct flights from Panama City, Florida to Italy. There are no popular flight routes from Panama City, Florida to Italy.
Search flight deals

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Italy?

    Prices for flights from Panama City NW Florida Beaches Airport to Italy were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Italy?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Italy?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Italy.

  • What documentation or ID do you need to fly to Italy?

    The travel and health documents required for your trip to Italy can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Italy. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Panama City, Florida to Italy

Compare and see reviews for airlines that fly from Panama City, Florida to Italy with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $729Free CancellationRating
7.9
8,013 reviews
Search Delta flights
KLMPriceFrom $783Free CancellationRating
7.7
1,432 reviews
Search KLM flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Italy?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Italy from Panama City.

Can I find flights from Panama City to Italy with flexible booking policies on momondo?

momondo does allow users to show only those flights to Italy from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Italy?

momondo provides multiple filters to help you find the best flight to Italy from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Italy right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Italy from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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