Cheap flights from Orlando Airport to Santiago from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Santiago departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
3:40 pm - 6:00 am
MCO
-
SCL
14h 20m
1 stop
LATAM Airlines Logo
1:30 pm - 1:55 pm
SCL
-
MCO
24h 25m
2 stops
$505LATAM Airlines
Thu, Apr 16 - Tue, Apr 28
LATAM Airlines Logo
1:00 pm - 5:45 am
MCO
-
SCL
16h 45m
2 stops
LATAM Airlines Logo
7:55 pm - 1:55 pm
SCL
-
MCO
18h 00m
2 stops
$509LATAM Airlines
Thu, Apr 16 - Tue, Apr 28
Avianca Logo
11:40 pm - 2:15 pm
MCO
-
SCL
14h 35m
1 stop
Avianca Logo
6:40 am - 9:20 pm
SCL
-
MCO
14h 40m
1 stop
$511Avianca
Sun, Apr 19 - Sun, Apr 26
Copa Airlines Logo
2:42 pm - 2:20 am
MCO
-
SCL
11h 38m
1 stop
Copa Airlines Logo
2:22 am - 1:48 pm
SCL
-
MCO
11h 26m
1 stop
$513Copa Airlines
Mon, May 4 - Wed, May 27
LATAM Airlines Logo
5:30 pm - 2:05 pm
MCO
-
SCL
20h 35m
2 stops
LATAM Airlines Logo
12:35 pm - 3:50 pm
SCL
-
MCO
27h 15m
2 stops
$515LATAM Airlines
Wed, Apr 8 - Sun, Apr 26
LATAM Airlines Logo
4:20 pm - 6:55 am
MCO
-
SCL
14h 35m
2 stops
LATAM Airlines Logo
7:00 pm - 4:20 pm
SCL
-
MCO
21h 20m
1 stop
$518LATAM Airlines
Tue, May 5 - Tue, May 12
LATAM Airlines Logo
7:50 pm - 1:45 pm
MCO
-
SCL
17h 55m
2 stops
LATAM Airlines Logo
7:55 pm - 1:55 pm
SCL
-
MCO
18h 00m
2 stops
$520LATAM Airlines
Tue, Apr 7 - Mon, Apr 27
LATAM Airlines Logo
5:30 pm - 6:00 am
MCO
-
SCL
12h 30m
1 stop
LATAM Airlines Logo
7:55 pm - 12:55 pm
SCL
-
MCO
17h 00m
2 stops
$521LATAM Airlines
Wed, Apr 22 - Fri, Apr 24
Avianca Logo
11:40 pm - 2:15 pm
MCO
-
SCL
14h 35m
1 stop
Avianca Logo
6:40 am - 9:20 pm
SCL
-
MCO
14h 40m
1 stop
$524Avianca
Wed, Apr 22 - Fri, Apr 24
LATAM Airlines Logo
6:45 pm - 5:25 pm
MCO
-
SCL
22h 40m
2 stops
LATAM Airlines Logo
10:55 pm - 2:34 pm
SCL
-
MCO
15h 39m
1 stop
$525LATAM Airlines
Mon, May 4 - Thu, May 28

LATAM Airlines flights from Orlando Airport to Santiago

Our best LATAM Airlines deals on Orlando Airport to Santiago flight tickets
LATAM Airlines
Apr 16
MCO3:40 pmOrlando
14h 20m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Apr 28
SCL1:30 pmSantiago Arturo Merino Benitez
24h 25m
2 stops
MCO1:55 pmOrlando
$505
LATAM Airlines
Apr 16
MCO1:00 pmOrlando
16h 45m
2 stops
SCL5:45 amSantiago Arturo Merino Benitez
Apr 28
SCL7:55 pmSantiago Arturo Merino Benitez
18h 00m
2 stops
MCO1:55 pmOrlando
$509
LATAM Airlines
Apr 8
MCO5:30 pmOrlando
20h 05m
1 stop
SCL1:35 pmSantiago Arturo Merino Benitez
Apr 26
SCL12:35 pmSantiago Arturo Merino Benitez
27h 15m
2 stops
MCO3:50 pmOrlando
$515

Copa Airlines flights from Orlando Airport to Santiago

Our best Copa Airlines deals on Orlando Airport to Santiago flight tickets
Copa Airlines
May 4
MCO2:42 pmOrlando
11h 38m
1 stop
SCL2:20 amSantiago Arturo Merino Benitez
May 27
SCL2:22 amSantiago Arturo Merino Benitez
11h 26m
1 stop
MCO1:48 pmOrlando
$513
Copa Airlines
Apr 6
MCO3:25 pmOrlando
13h 45m
1 stop
SCL5:10 amSantiago Arturo Merino Benitez
Apr 10
SCL11:25 amSantiago Arturo Merino Benitez
11h 15m
1 stop
MCO10:40 pmOrlando
$533
Copa Airlines
Apr 7
MCO3:25 pmOrlando
13h 45m
1 stop
SCL5:10 amSantiago Arturo Merino Benitez
Apr 10
SCL11:25 amSantiago Arturo Merino Benitez
11h 04m
1 stop
MCO10:29 pmOrlando
$544

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Orlando Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Thu 4/16

3:40 pm-6:00 am

1 stop14h 20m

Santiago Arturo Merino Benitez

Tue 4/28

1:30 pm-1:55 pm

2 stops24h 25m

$505

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Thu 4/16

1:00 pm-5:45 am

2 stops16h 45m

Santiago Arturo Merino Benitez

Tue 4/28

7:55 pm-1:55 pm

2 stops18h 00m

$509

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Sun 4/19

11:40 pm-2:15 pm

1 stop14h 35m

Santiago Arturo Merino Benitez

Sun 4/26

6:40 am-9:20 pm

1 stop14h 40m

$511
Quickest round-trip

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Mon 5/4

2:42 pm-2:20 am

1 stop11h 38m

Santiago Arturo Merino Benitez

Wed 5/27

2:22 am-1:48 pm

1 stop11h 26m

$513

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Wed 4/8

5:30 pm-2:05 pm

2 stops20h 35m

Santiago Arturo Merino Benitez

Sun 4/26

12:35 pm-3:50 pm

2 stops27h 15m

$515

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Tue 5/5

4:20 pm-6:55 am

2 stops14h 35m

Santiago Arturo Merino Benitez

Tue 5/12

7:00 pm-4:20 pm

1 stop21h 20m

$518

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Tue 4/7

7:50 pm-1:45 pm

2 stops17h 55m

Santiago Arturo Merino Benitez

Mon 4/27

7:55 pm-1:55 pm

2 stops18h 00m

$520

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Wed 4/22

5:30 pm-6:00 am

1 stop12h 30m

Santiago Arturo Merino Benitez

Fri 4/24

7:55 pm-12:55 pm

2 stops17h 00m

$521

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Wed 4/22

11:40 pm-2:15 pm

1 stop14h 35m

Santiago Arturo Merino Benitez

Fri 4/24

6:40 am-9:20 pm

1 stop14h 40m

$524

OrlandoSantiago

MCO - SCL

MCOSCL

Orlando

Mon 5/4

6:45 pm-5:25 pm

2 stops22h 40m

Santiago Arturo Merino Benitez

Thu 5/28

10:55 pm-2:34 pm

1 stop15h 39m

$525

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Orlando Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Orlando Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $519. If you don’t want to visit Santiago in September, then you should wait until August to fly from Orlando Airport, when ticket prices are also cheap, with an average price of $528.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Friday when prices can be found for as low as $564. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $931.

What is the cheapest Orlando to Santiago Arturo Merino Benitez flight route?

Fly from Orlando to Santiago Arturo Merino Benitez for the best Orlando - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Orlando Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $607 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Orlando Airport for as low as $520 on momondo.

What cabin class options are available on Orlando to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Orlando to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando Airport to Santiago flights?

You could potentially save up to 3% on your flight if you consider stops on a Orlando Airport to Santiago flight.

How have Orlando Airport to Santiago flight prices changed over time?

As of March 2026, prices for Orlando Airport to Santiago flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Santiago (MCO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Santiago

Best Price Found

$523

Fastest flight time

11h 37m

Direct flights

None
The best one-way flight to Santiago from Orlando Airport in the past 72 hours is $523. The best round-trip flight deal from Orlando Airport to Santiago found on momondo in the last 72 hours is $926.
The fastest flight from Orlando Airport to Santiago takes 11h 37m
There are no direct flights from Orlando Airport to Santiago. There are no popular flight routes from Orlando Airport to Santiago.
  • How far is Orlando to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 4328.9 mi away from Orlando. A reasonable flight in good conditions will take 11h 37m.

  • When did momondo last update prices for flights from Orlando Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Orlando Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Orlando Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Orlando Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Santiago?

  • What is the most popular airline from Orlando Airport to Santiago?

Best airlines flying from Orlando Airport to Santiago

Compare and see reviews for airlines that fly from Orlando Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $335Free CancellationRating
6.5
2,505 reviews
Search Avianca flights
Copa AirlinesPriceFrom $447Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $463Free CancellationRating
7.4
9,464 reviews
Search United Airlines flights
American AirlinesPriceFrom $463Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $479Free CancellationRating
7.4
1,911 reviews
Search LATAM Airlines flights
DeltaPriceFrom $519Free CancellationRating
7.9
8,317 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Santiago?

Finding the right flight to Santiago from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Orlando to Santiago with flexible booking policies on momondo?

All flight searches from Orlando to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Orlando to Santiago?

Once you have performed a search for Orlando to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Orlando to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Wed 4/22
Wed 4/29

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