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Cheap flights from Myrtle Beach to Chicago from $114

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:42 pm - 12:26 amMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
10h 44m2 stops Fort Lauderdale Dallas/Fort Worth
Multiple Airlines Logo
8:04 am - 9:13 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
24h 09m1 stop Fort Lauderdale
$288Multiple Airlines
Wed, Oct 14 - Tue, Oct 20
Multiple Airlines Logo
2:42 pm - 12:26 amMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
10h 44m2 stops Fort Lauderdale Dallas/Fort Worth
Multiple Airlines Logo
8:04 am - 9:55 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
24h 51m1 stop Fort Lauderdale
$292Multiple Airlines
Wed, Oct 21 - Mon, Oct 26
Multiple Airlines Logo
1:53 pm - 3:30 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
26h 37m1 stop Fort Lauderdale
Multiple Airlines Logo
8:04 am - 9:55 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
24h 51m1 stop Fort Lauderdale
$302Multiple Airlines
Mon, Oct 19 - Mon, Oct 26
Multiple Airlines Logo
2:42 pm - 3:30 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
25h 48m1 stop Fort Lauderdale
Multiple Airlines Logo
4:41 pm - 8:47 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
15h 06m1 stop Philadelphia
$303Multiple Airlines
Wed, Oct 21 - Sat, Oct 24
American Airlines Logo
6:12 am - 12:19 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
7h 07m1 stop Charlotte Douglas
American Airlines Logo
9:00 am - 4:23 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
6h 23m1 stop Charlotte Douglas
$377American Airlines
Sat, Nov 14 - Tue, Nov 17
American Airlines Logo
12:12 pm - 6:33 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
7h 21m1 stop Washington, D.C. Reagan-National
American Airlines Logo
5:19 am - 10:21 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
4h 02m1 stop Charlotte Douglas
$377American Airlines
Mon, Nov 2 - Thu, Nov 12
American Airlines Logo
1:52 pm - 5:38 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
4h 46m1 stop Charlotte Douglas
American Airlines Logo
6:02 am - 11:42 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
4h 40m1 stop Washington, D.C. Reagan-National
$377American Airlines
Mon, Nov 9 - Thu, Nov 12
United Airlines Logo
5:00 pm - 6:36 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
2h 36mnonstop
United Airlines Logo
11:55 am - 3:16 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
2h 21mnonstop
$406United Airlines
Wed, Oct 14 - Tue, Oct 20
United Airlines Logo
5:00 pm - 6:36 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
2h 36mnonstop
United Airlines Logo
11:55 am - 3:16 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
2h 21mnonstop
$407United Airlines
Wed, Oct 14 - Wed, Oct 21
United Airlines Logo
5:00 pm - 6:36 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
2h 36mnonstop
United Airlines Logo
5:00 am - 11:38 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
5h 38m1 stop Newark
$416United Airlines
Wed, Oct 14 - Tue, Oct 20

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American Airlines flights from Myrtle Beach to Chicago O'Hare Intl Airport

Our best American Airlines deals on Myrtle Beach to Chicago O'Hare Intl Airport flight tickets
American Airlines
Nov 21
MYR11:06 amMyrtle Beach Intl
6h 10m
1 stop
ORD4:16 pmChicago O'Hare Intl
Nov 24
ORD8:05 amChicago O'Hare Intl
6h 36m
1 stop
MYR3:41 pmMyrtle Beach Intl
$391
American Airlines
Dec 4
MYR1:17 pmMyrtle Beach Intl
5h 14m
1 stop
ORD5:31 pmChicago O'Hare Intl
Dec 15
ORD6:43 amChicago O'Hare Intl
5h 41m
1 stop
MYR1:24 pmMyrtle Beach Intl
$393
American Airlines
Oct 14
MYR11:55 amMyrtle Beach Intl
6h 22m
1 stop
ORD5:17 pmChicago O'Hare Intl
Oct 21
ORD8:05 amChicago O'Hare Intl
6h 37m
1 stop
MYR3:42 pmMyrtle Beach Intl
$426

United Airlines flights from Myrtle Beach to Chicago O'Hare Intl Airport

Our best United Airlines deals on Myrtle Beach to Chicago O'Hare Intl Airport flight tickets
United Airlines
Oct 14
MYR5:00 pmMyrtle Beach Intl
2h 36m
ORD6:36 pmChicago O'Hare Intl
Oct 20
ORD11:55 amChicago O'Hare Intl
2h 21m
MYR3:16 pmMyrtle Beach Intl
$406
United Airlines
Oct 14
MYR5:00 pmMyrtle Beach Intl
2h 36m
ORD6:36 pmChicago O'Hare Intl
Oct 21
ORD11:55 amChicago O'Hare Intl
2h 21m
MYR3:16 pmMyrtle Beach Intl
$407
United Airlines
Oct 14
MYR10:23 amMyrtle Beach Intl
5h 03m
1 stop
ORD2:26 pmChicago O'Hare Intl
Oct 21
ORD11:55 amChicago O'Hare Intl
2h 21m
MYR3:16 pmMyrtle Beach Intl
$416

momondo Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/14

2:42 pm-12:26 am

2 stops10h 44m

Chicago O'Hare Intl

Tue 10/20

8:04 am-9:13 am

1 stop24h 09m

$288

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/21

2:42 pm-12:26 am

2 stops10h 44m

Chicago O'Hare Intl

Mon 10/26

8:04 am-9:55 am

1 stop24h 51m

$292

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 10/19

1:53 pm-3:30 pm

1 stop26h 37m

Chicago O'Hare Intl

Mon 10/26

8:04 am-9:55 am

1 stop24h 51m

$302

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/21

2:42 pm-3:30 pm

1 stop25h 48m

Chicago O'Hare Intl

Sat 10/24

4:41 pm-8:47 am

1 stop15h 06m

$303

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Sat 11/14

6:12 am-12:19 pm

1 stop7h 07m

Chicago O'Hare Intl

Tue 11/17

9:00 am-4:23 pm

1 stop6h 23m

$377

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 11/2

12:12 pm-6:33 pm

1 stop7h 21m

Chicago O'Hare Intl

Thu 11/12

5:19 am-10:21 am

1 stop4h 02m

$377

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 11/9

1:52 pm-5:38 pm

1 stop4h 46m

Chicago O'Hare Intl

Thu 11/12

6:02 am-11:42 am

1 stop4h 40m

$377
Quickest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/14

5:00 pm-6:36 pm

Nonstop2h 36m

Chicago O'Hare Intl

Tue 10/20

11:55 am-3:16 pm

Nonstop2h 21m

$406

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/14

5:00 pm-6:36 pm

Nonstop2h 36m

Chicago O'Hare Intl

Wed 10/21

11:55 am-3:16 pm

Nonstop2h 21m

$407

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 10/14

5:00 pm-6:36 pm

Nonstop2h 36m

Chicago O'Hare Intl

Tue 10/20

5:00 am-11:38 am

1 stop5h 38m

$416

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Chicago O'Hare Intl Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $395 to $450.
The lowest price recently found on this route was $288.

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of April is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Myrtle Beach averaging around $306.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Tuesday when prices can be found for as low as $383. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $638.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Myrtle Beach in the morning is the least expensive time of day to depart. momondo users have found prices as low as $463 when looking at flights departing in the morning. Try not to purchase tickets in the afternoon because they tend to be around $472. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Myrtle Beach Intl to Chicago O'Hare Intl flight route?

Fly from Myrtle Beach Intl to Chicago O'Hare Intl for the best Myrtle Beach Intl - Chicago O'Hare Intl flight prices

What cabin class options are available on Myrtle Beach to Chicago O'Hare Intl Airport flights?

There are 4 cabin classes available to choose from on Myrtle Beach to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago O'Hare Intl Airport flights?

You could potentially save up to 9% on your flight if you consider stops on a Myrtle Beach to Chicago O'Hare Intl Airport flight.

How have Myrtle Beach to Chicago O'Hare Intl Airport flight prices changed over time?

As of October 2026, prices for Myrtle Beach to Chicago O'Hare Intl Airport flights are approximately 495% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago O'Hare Intl Airport (MYR to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago O'Hare Intl Airport

Best Price Found

$114

Fastest flight time

2h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Myrtle Beach in the past 72 hours is $114. The best round-trip flight deal from Myrtle Beach to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $288.
The fastest flight from Myrtle Beach to Chicago O'Hare Intl Airport takes 2h 36m
Direct flights go from Myrtle Beach to Chicago O'Hare Intl Airport every day.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Chicago O'Hare Intl Airport

  • How far is Myrtle Beach Intl to Chicago O'Hare Intl by plane?

    The straight-line distance from Myrtle Beach Intl to Chicago O'Hare Intl is 753.7 mi. 2h 36m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Chicago O'Hare Intl Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago O'Hare Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago O'Hare Intl Airport?

  • What is the most popular airline from Myrtle Beach to Chicago O'Hare Intl Airport?

Best airlines flying from Myrtle Beach to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $238Free CancellationRating
7.4
10,270 reviews
Search United Airlines flights
American AirlinesPriceFrom $299Free CancellationRating
7.0
12,101 reviews
Search American Airlines flights

  • United Airlines Flights From Myrtle Beach to Chicago O'Hare Intl Airport

    United Airlines operates around 5 flights from Myrtle Beach to Chicago O'Hare Intl Airport every week. The average price of these flights found in the last 72 hours has been $417, but momondo users have found United Airlines deals from Myrtle Beach to Chicago O'Hare Intl Airport from as low as $238 round-trip. United Airlines has been scored 7.4/10 in 10,270 reviews.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Schaumburg
Merrillville
Rockford
South Haven
Rosemont
Gurnee
Oak Brook
Orland Park
Joliet
Naperville
New Buffalo
Kenosha
Hammond
Aurora
Racine
Elgin
Janesville
Evanston
Skokie

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Chicago for you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

Once all potential Myrtle Beach to Chicago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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