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Cheap flights from Myrtle Beach to Detroit from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Detroit departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:21 pm - 9:06 pm
MYR
-
DTW
4h 45m
1 stop
Multiple Airlines Logo
9:16 am - 2:44 pm
DTW
-
MYR
5h 28m
1 stop
$183Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Spirit Airlines Logo
10:20 am - 12:52 pm
MYR
-
DTW
26h 32m
1 stop
Spirit Airlines Logo
8:30 pm - 2:44 pm
DTW
-
MYR
18h 14m
1 stop
$217Spirit Airlines
Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
4:23 pm - 11:40 am
MYR
-
DTW
19h 17m
1 stop
Multiple Airlines Logo
9:16 am - 2:44 pm
DTW
-
MYR
5h 28m
1 stop
$219Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
Spirit Airlines Logo
12:00 pm - 6:53 pm
MYR
-
DTW
6h 53m
1 stop
Spirit Airlines Logo
9:16 am - 2:44 pm
DTW
-
MYR
5h 28m
1 stop
$221Spirit Airlines
Fri, May 8 - Tue, May 19
Multiple Airlines Logo
6:28 pm - 11:59 pm
MYR
-
DTW
5h 31m
1 stop
Multiple Airlines Logo
10:02 am - 2:28 pm
DTW
-
MYR
4h 26m
1 stop
$222Multiple Airlines
Tue, Apr 7 - Sat, Apr 11
Multiple Airlines Logo
4:23 pm - 11:40 am
MYR
-
DTW
19h 17m
1 stop
Multiple Airlines Logo
8:43 pm - 8:41 am
DTW
-
MYR
35h 58m
2 stops
$225Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
Multiple Airlines Logo
10:20 am - 10:52 pm
MYR
-
DTW
12h 32m
1 stop
Multiple Airlines Logo
8:43 pm - 8:41 am
DTW
-
MYR
35h 58m
2 stops
$233Multiple Airlines
Mon, Apr 20 - Mon, Apr 27
Spirit Airlines Logo
2:23 pm - 6:53 pm
MYR
-
DTW
4h 30m
1 stop
Spirit Airlines Logo
9:16 am - 2:44 pm
DTW
-
MYR
5h 28m
1 stop
$235Spirit Airlines
Thu, Apr 16 - Wed, Apr 22
Spirit Airlines Logo
12:05 pm - 10:59 pm
MYR
-
DTW
10h 54m
1 stop
Spirit Airlines Logo
8:15 am - 5:33 pm
DTW
-
MYR
9h 18m
1 stop
$237Spirit Airlines
Tue, Apr 7 - Wed, Apr 8
Spirit Airlines Logo
12:05 pm - 10:59 pm
MYR
-
DTW
10h 54m
1 stop
Spirit Airlines Logo
9:16 am - 2:44 pm
DTW
-
MYR
5h 28m
1 stop
$239Spirit Airlines
Tue, Apr 14 - Tue, Apr 21

Spirit Airlines flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Our best Spirit Airlines deals on Myrtle Beach to Detroit Metropolitan Wayne County Airport flight tickets
Spirit Airlines
Apr 17
MYR10:20 amMyrtle Beach Intl
26h 32m
1 stop
DTW12:52 pmDetroit Metropolitan Wayne County
Apr 20
DTW8:30 pmDetroit Metropolitan Wayne County
18h 14m
1 stop
MYR2:44 pmMyrtle Beach Intl
$217
Spirit Airlines
May 8
MYR12:00 pmMyrtle Beach Intl
6h 53m
1 stop
DTW6:53 pmDetroit Metropolitan Wayne County
May 19
DTW9:16 amDetroit Metropolitan Wayne County
5h 28m
1 stop
MYR2:44 pmMyrtle Beach Intl
$221
Spirit Airlines
Mar 28
MYR6:28 pmMyrtle Beach Intl
5h 31m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
Apr 4
DTW6:50 pmDetroit Metropolitan Wayne County
16h 15m
2 stops
MYR11:05 amMyrtle Beach Intl
$233

Delta flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Myrtle Beach to Detroit Metropolitan Wayne County Airport flight tickets
Delta
May 22
MYR11:32 amMyrtle Beach Intl
1h 58m
DTW1:30 pmDetroit Metropolitan Wayne County
May 25
DTW8:40 amDetroit Metropolitan Wayne County
1h 57m
MYR10:37 amMyrtle Beach Intl
$339
Delta
May 22
MYR11:32 amMyrtle Beach Intl
1h 58m
DTW1:30 pmDetroit Metropolitan Wayne County
May 25
DTW8:30 amDetroit Metropolitan Wayne County
6h 51m
1 stop
MYR3:21 pmMyrtle Beach Intl
$349

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Mon 4/13

4:21 pm-9:06 pm

1 stop4h 45m

Detroit Metropolitan Wayne County

Thu 4/16

9:16 am-2:44 pm

1 stop5h 28m

$183

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Fri 4/17

10:20 am-12:52 pm

1 stop26h 32m

Detroit Metropolitan Wayne County

Mon 4/20

8:30 pm-2:44 pm

1 stop18h 14m

$217

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Thu 4/23

4:23 pm-11:40 am

1 stop19h 17m

Detroit Metropolitan Wayne County

Mon 4/27

9:16 am-2:44 pm

1 stop5h 28m

$219

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Fri 5/8

12:00 pm-6:53 pm

1 stop6h 53m

Detroit Metropolitan Wayne County

Tue 5/19

9:16 am-2:44 pm

1 stop5h 28m

$221
Quickest round-trip

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Tue 4/7

6:28 pm-11:59 pm

1 stop5h 31m

Detroit Metropolitan Wayne County

Sat 4/11

10:02 am-2:28 pm

1 stop4h 26m

$222

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Thu 4/23

4:23 pm-11:40 am

1 stop19h 17m

Detroit Metropolitan Wayne County

Mon 4/27

8:43 pm-8:41 am

2 stops35h 58m

$225

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Mon 4/20

10:20 am-10:52 pm

1 stop12h 32m

Detroit Metropolitan Wayne County

Mon 4/27

8:43 pm-8:41 am

2 stops35h 58m

$233

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Thu 4/16

2:23 pm-6:53 pm

1 stop4h 30m

Detroit Metropolitan Wayne County

Wed 4/22

9:16 am-2:44 pm

1 stop5h 28m

$235

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Tue 4/7

12:05 pm-10:59 pm

1 stop10h 54m

Detroit Metropolitan Wayne County

Wed 4/8

8:15 am-5:33 pm

1 stop9h 18m

$237

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Tue 4/14

12:05 pm-10:59 pm

1 stop10h 54m

Detroit Metropolitan Wayne County

Tue 4/21

9:16 am-2:44 pm

1 stop5h 28m

$239

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Detroit Metropolitan Wayne County Airport?

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Myrtle Beach is in July. Flight prices, which tend to average around $159, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of July, then book flights to Detroit Metropolitan Wayne County Airport from Myrtle Beach during August instead. Flights to Detroit Metropolitan Wayne County Airport in August, while not as cheap as those in July, still average around $174.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Myrtle Beach to Detroit Metropolitan Wayne County Airport is on a Sunday when prices can be found for as low as $259. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Tuesday is $573.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Myrtle Beach in the evening is the least expensive time of day to depart. momondo users have found prices as low as $172 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly at noon, with an average ticket price of $439. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Myrtle Beach Intl to Detroit Metropolitan Wayne County flight route?

Fly from Myrtle Beach Intl to Detroit Metropolitan Wayne County for the best Myrtle Beach Intl - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Myrtle Beach Intl to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Myrtle Beach Intl to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Detroit Metropolitan Wayne County Airport flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Detroit Metropolitan Wayne County Airport.

How have Myrtle Beach to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of March 2026, prices for Myrtle Beach to Detroit Metropolitan Wayne County Airport flights are approximately 27% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Detroit Metropolitan Wayne County Airport (MYR to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Best Price Found

$269

Fastest flight time

1h 55m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Myrtle Beach in the past 72 hours is $269. The best round-trip flight deal from Myrtle Beach to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $438.
The fastest flight from Myrtle Beach to Detroit Metropolitan Wayne County Airport takes 1h 55m
Direct flights go from Myrtle Beach to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

  • How far is Myrtle Beach Intl to Detroit Metropolitan Wayne County by plane?

    There are 637.1 mi between Myrtle Beach Intl and Detroit Metropolitan Wayne County. Typically, this will take 1h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Myrtle Beach Intl Airport to Detroit Metropolitan Wayne County Airport are updated daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Myrtle Beach to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Myrtle Beach to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Myrtle Beach to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $78Free CancellationRating
6.3
8,539 reviews
Search Spirit Airlines flights
DeltaPriceFrom $158Free CancellationRating
7.9
8,326 reviews
Search Delta flights
American AirlinesPriceFrom $198Free CancellationRating
7.1
11,494 reviews
Search American Airlines flights

  • Delta Flights From Myrtle Beach to Detroit Metropolitan Wayne County Airport

    Delta operates around 3 flights from Myrtle Beach to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $299, but momondo users have found Delta deals from Myrtle Beach to Detroit Metropolitan Wayne County Airport from as low as $158 round-trip. Delta has been scored 7.9/10 in 8,326 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Port Huron
Sterling Heights
Dundee
Brighton
Ypsilanti
Pontiac
Farmington Hills
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Detroit?

It is quick and easy to find Myrtle Beach to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Myrtle Beach to Detroit with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Detroit on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Detroit?

momondo provides multiple filters to help you find the best flight to Detroit from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Detroit right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Detroit now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Detroit and let you know when they change.

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