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Cheap flights from Myrtle Beach to Central America from $154

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
9:09 am - 12:22 pm
MYR
-
SJO
28h 13m1 stop
Spirit Airlines Logo
1:31 pm - 8:13 am
SJO
-
MYR
17h 42m1 stop
$324Spirit Airlines
Thu, Feb 12 - Thu, Feb 19
Spirit Airlines Logo
8:15 pm - 12:22 pm
MYR
-
SJO
17h 07m1 stop
Spirit Airlines Logo
12:35 pm - 11:44 am
SJO
-
MYR
22h 09m1 stop
$346Spirit Airlines
Sun, Feb 8 - Sat, Feb 14
Spirit Airlines Logo
8:15 pm - 11:37 am
MYR
-
SJO
40h 22m2 stops
Spirit Airlines Logo
1:30 pm - 7:20 pm
SJO
-
MYR
28h 50m1 stop
$347Spirit Airlines
Sat, Jan 17 - Sun, Jan 25
Spirit Airlines Logo
8:15 pm - 11:37 am
MYR
-
SJO
40h 22m2 stops
Spirit Airlines Logo
12:33 pm - 7:20 pm
SJO
-
MYR
29h 47m2 stops
$353Spirit Airlines
Tue, Feb 3 - Tue, Feb 10
Multiple Airlines Logo
8:15 pm - 11:37 am
MYR
-
SJO
40h 22m2 stops
Multiple Airlines Logo
10:45 pm - 9:03 am
SJO
-
MYR
33h 18m2 stops
$363Multiple Airlines
Sat, Jan 17 - Sun, Jan 25
American Airlines Logo
4:07 pm - 12:15 pm
MYR
-
PTY
21h 08m2 stops
American Airlines Logo
1:55 pm - 11:37 am
PTY
-
MYR
20h 42m2 stops
$440American Airlines
Tue, Apr 7 - Tue, Apr 14
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 5:58 pm
PTY
-
MYR
26h 38m1 stop
$443Delta
Wed, Apr 8 - Thu, Apr 16
Delta Logo
6:58 pm - 12:55 pm
MYR
-
PTY
18h 57m1 stop
Delta Logo
2:20 pm - 5:58 pm
PTY
-
MYR
26h 38m1 stop
$450Delta
Mon, Apr 6 - Thu, Apr 16
American Airlines Logo
5:29 pm - 3:38 pm
MYR
-
PTY
22h 09m2 stops
American Airlines Logo
4:50 pm - 1:23 pm
PTY
-
MYR
20h 33m2 stops
$460American Airlines
Thu, Feb 5 - Mon, Feb 9
United Airlines Logo
11:25 am - 7:31 pm
MYR
-
PTY
9h 06m1 stop
United Airlines Logo
10:55 pm - 10:40 am
PTY
-
MYR
10h 45m1 stop
$533United Airlines
Sat, May 16 - Sat, May 23

Spirit Airlines flights from Myrtle Beach to Central America

Our best Spirit Airlines deals on Myrtle Beach to Central America flight tickets
Spirit Airlines
Feb 12
MYR9:09 amMyrtle Beach Intl
28h 13m
1 stop
SJO12:22 pmSan José Juan Santamaria Intl
Feb 19
SJO1:31 pmSan José Juan Santamaria Intl
17h 42m
1 stop
MYR8:13 amMyrtle Beach Intl
$324
Find similar
Spirit Airlines
Feb 8
MYR8:15 pmMyrtle Beach Intl
17h 07m
1 stop
SJO12:22 pmSan José Juan Santamaria Intl
Feb 14
SJO12:35 pmSan José Juan Santamaria Intl
22h 09m
1 stop
MYR11:44 amMyrtle Beach Intl
$346
Find similar
Spirit Airlines
Jan 17
MYR8:15 pmMyrtle Beach Intl
40h 22m
2 stops
SJO11:37 amSan José Juan Santamaria Intl
Jan 25
SJO1:30 pmSan José Juan Santamaria Intl
28h 50m
1 stop
MYR7:20 pmMyrtle Beach Intl
$347
Find similar

American Airlines flights from Myrtle Beach to Central America

Our best American Airlines deals on Myrtle Beach to Central America flight tickets
American Airlines
Apr 7
MYR4:07 pmMyrtle Beach Intl
21h 08m
2 stops
PTY12:15 pmPanama City Tocumen Intl
Apr 14
PTY1:55 pmPanama City Tocumen Intl
20h 42m
2 stops
MYR11:37 amMyrtle Beach Intl
$440
Find similar
American Airlines
Feb 5
MYR5:29 pmMyrtle Beach Intl
22h 09m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Feb 9
PTY4:50 pmPanama City Tocumen Intl
20h 33m
2 stops
MYR1:23 pmMyrtle Beach Intl
$460
Find similar
American Airlines
Apr 8
MYR5:28 amMyrtle Beach Intl
7h 07m
2 stops
BZE10:35 amBelize City Philip S.W.Goldson
Apr 16
BZE3:15 pmBelize City Philip S.W.Goldson
22h 27m
2 stops
MYR3:42 pmMyrtle Beach Intl
$469
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Thu 2/12

9:09 am-12:22 pm

1 stop28h 13m

San José Juan Santamaria Intl

Thu 2/19

1:31 pm-8:13 am

1 stop17h 42m

$324

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 2/8

8:15 pm-12:22 pm

1 stop17h 07m

San José Juan Santamaria Intl

Sat 2/14

12:35 pm-11:44 am

1 stop22h 09m

$346

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 1/17

8:15 pm-11:37 am

2 stops40h 22m

San José Juan Santamaria Intl

Sun 1/25

1:30 pm-7:20 pm

1 stop28h 50m

$347

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Tue 2/3

8:15 pm-11:37 am

2 stops40h 22m

San José Juan Santamaria Intl

Tue 2/10

12:33 pm-7:20 pm

2 stops29h 47m

$353

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 1/17

8:15 pm-11:37 am

2 stops40h 22m

San José Juan Santamaria Intl

Sun 1/25

10:45 pm-9:03 am

2 stops33h 18m

$363

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 4/7

4:07 pm-12:15 pm

2 stops21h 08m

Panama City Tocumen Intl

Tue 4/14

1:55 pm-11:37 am

2 stops20h 42m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 4/8

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 4/16

2:20 pm-5:58 pm

1 stop26h 38m

$443

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 4/6

6:58 pm-12:55 pm

1 stop18h 57m

Panama City Tocumen Intl

Thu 4/16

2:20 pm-5:58 pm

1 stop26h 38m

$450

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 2/5

5:29 pm-3:38 pm

2 stops22h 09m

Panama City Tocumen Intl

Mon 2/9

4:50 pm-1:23 pm

2 stops20h 33m

$460

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 5/16

11:25 am-7:31 pm

1 stop9h 06m

Panama City Tocumen Intl

Sat 5/23

10:55 pm-10:40 am

1 stop10h 45m

$533

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, May is the cheapest month to fly from Myrtle Beach to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $292. If you don’t want to visit Central America in May, then you should wait until August to fly from Myrtle Beach, when ticket prices are also cheap, with an average price of $399.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Myrtle Beach to Central America is on a Wednesday. Travelers who choose to depart for Central America on a Wednesday will often find tickets for as low as $321. On the other hand, Friday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $724.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Myrtle Beach to Central America flights are usually those with departure times in the evening. Our users have found flights to Central America in the evening for as low as $346. Try not to purchase tickets in the morning because they tend to be around $671. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Myrtle Beach to Central America flights?

You could potentially save up to 58% on your flight if you consider stops on a Myrtle Beach to Central America flight.

Cheap Myrtle Beach to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Central America

Fastest flight time

7h 15m

Direct flights

None
The fastest flight from Myrtle Beach to Central America takes 7h 15m
There are no direct flights from Myrtle Beach to Central America. There are no popular flight routes from Myrtle Beach to Central America.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Central America?

    Prices for flights from Myrtle Beach Intl Airport to Central America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Central America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to Central America

Compare and see reviews for airlines that fly from Myrtle Beach to Central America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $267Free CancellationRating
6.3
8,187 reviews
Search Spirit Airlines flights
DeltaPriceFrom $378Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $464Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Myrtle Beach to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Myrtle Beach to Central America with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Central America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Central America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Central America.

I’m not ready to book a flight from Myrtle Beach to Central America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Central America, momondo offers a useful price alert feature which will track prices for flights to Central America from Myrtle Beach and alert you when they change.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

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