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Cheap flights from Myrtle Beach to Central America from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Spirit Airlines Logo
9:54 am - 12:25 pmMYR-SJO
27h 31m1 stop
Spirit Airlines Logo
1:31 pm - 5:48 pmSJO-MYR
27h 17m1 stop
$297Spirit Airlines
Find Deal
Fri, Dec 5 - Wed, Dec 10
Spirit Airlines Logo
11:46 am - 12:21 amMYR-SJO
13h 35m1 stop
Spirit Airlines Logo
1:16 am - 10:41 amSJO-MYR
8h 25m1 stop
$300Spirit Airlines
Find Deal
Mon, Jan 26 - Sun, Feb 1
Spirit Airlines Logo
6:15 am - 11:39 amMYR-SJO
6h 24m1 stop
Spirit Airlines Logo
1:20 pm - 11:54 pmSJO-MYR
9h 34m1 stop
$313Spirit Airlines
Find Deal
Sat, Nov 8 - Sat, Nov 22
Spirit Airlines Logo
6:15 am - 11:39 amMYR-SJO
6h 24m1 stop
Spirit Airlines Logo
1:30 pm - 10:26 pmSJO-MYR
7h 56m1 stop
$314Spirit Airlines
Find Deal
Mon, Nov 10 - Sun, Nov 16
Multiple Airlines Logo
9:54 am - 12:25 pmMYR-SJO
27h 31m1 stop
Multiple Airlines Logo
1:31 pm - 10:05 amSJO-MYR
19h 34m2 stops
$326Multiple Airlines
Find Deal
Fri, Dec 5 - Wed, Dec 10
Multiple Airlines Logo
6:15 am - 3:20 pmMYR-SJO
10h 05m1 stop
Multiple Airlines Logo
1:31 pm - 8:49 amSJO-MYR
18h 18m2 stops
$346Multiple Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
American Airlines Logo
6:40 pm - 12:10 pmMYR-PTY
18h 30m2 stops
American Airlines Logo
1:50 pm - 9:52 amPTY-MYR
19h 02m2 stops
$440American Airlines
Find Deal
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:43 pm - 1:47 pmMYR-PTY
19h 04m2 stops
American Airlines Logo
1:50 pm - 9:52 amPTY-MYR
19h 02m2 stops
$480American Airlines
Find Deal
Mon, Dec 15 - Thu, Mar 12
Delta Logo
6:00 am - 11:45 amMYR-GUA
7h 45m1 stop
Delta Logo
1:10 pm - 11:35 pmGUA-MYR
8h 25m1 stop
$570Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
Delta Logo
6:00 am - 11:45 amMYR-GUA
7h 45m1 stop
Delta Logo
1:10 pm - 11:35 pmGUA-MYR
8h 25m1 stop
$680Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11

Spirit Airlines flights from Myrtle Beach to Central America

Our best Spirit Airlines deals on Myrtle Beach to Central America flight tickets
Spirit Airlines
Dec 5
MYR9:54 amMyrtle Beach Intl
27h 31m
1 stop
SJO12:25 pmSan José Juan Santamaria Intl
Dec 10
SJO1:31 pmSan José Juan Santamaria Intl
27h 17m
1 stop
MYR5:48 pmMyrtle Beach Intl
$297
Find similar
Spirit Airlines
Jan 26
MYR11:46 amMyrtle Beach Intl
13h 35m
1 stop
SJO12:21 amSan José Juan Santamaria Intl
Feb 1
SJO1:16 amSan José Juan Santamaria Intl
8h 25m
1 stop
MYR10:41 amMyrtle Beach Intl
$300
Find similar
Spirit Airlines
Nov 8
MYR6:15 amMyrtle Beach Intl
6h 24m
1 stop
SJO11:39 amSan José Juan Santamaria Intl
Nov 22
SJO1:20 pmSan José Juan Santamaria Intl
9h 34m
1 stop
MYR11:54 pmMyrtle Beach Intl
$313
Find similar

American Airlines flights from Myrtle Beach to Central America

Our best American Airlines deals on Myrtle Beach to Central America flight tickets
American Airlines
Mar 19
MYR6:40 pmMyrtle Beach Intl
18h 30m
2 stops
PTY12:10 pmPanama City Tocumen Intl
Mar 26
PTY1:50 pmPanama City Tocumen Intl
19h 02m
2 stops
MYR9:52 amMyrtle Beach Intl
$440
Find similar
American Airlines
Dec 15
MYR6:43 pmMyrtle Beach Intl
19h 04m
2 stops
PTY1:47 pmPanama City Tocumen Intl
Mar 12
PTY1:50 pmPanama City Tocumen Intl
19h 02m
2 stops
MYR9:52 amMyrtle Beach Intl
$480
Find similar
American Airlines
Mar 1
MYR7:58 pmMyrtle Beach Intl
17h 34m
1 stop
SJO12:32 pmSan José Juan Santamaria Intl
Mar 4
SJO12:23 amSan José Juan Santamaria Intl
14h 58m
1 stop
MYR4:21 pmMyrtle Beach Intl
$494
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Fri 12/5

9:54 am-12:25 pm

1 stop27h 31m

San José Juan Santamaria Intl

Wed 12/10

1:31 pm-5:48 pm

1 stop27h 17m

$297

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 1/26

11:46 am-12:21 am

1 stop13h 35m

San José Juan Santamaria Intl

Sun 2/1

1:16 am-10:41 am

1 stop8h 25m

$300

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 11/8

6:15 am-11:39 am

1 stop6h 24m

San José Juan Santamaria Intl

Sat 11/22

1:20 pm-11:54 pm

1 stop9h 34m

$313

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Mon 11/10

6:15 am-11:39 am

1 stop6h 24m

San José Juan Santamaria Intl

Sun 11/16

1:30 pm-10:26 pm

1 stop7h 56m

$314

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Fri 12/5

9:54 am-12:25 pm

1 stop27h 31m

San José Juan Santamaria Intl

Wed 12/10

1:31 pm-10:05 am

2 stops19h 34m

$326

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 11/29

6:15 am-3:20 pm

1 stop10h 05m

San José Juan Santamaria Intl

Sat 12/6

1:31 pm-8:49 am

2 stops18h 18m

$346

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:40 pm-12:10 pm

2 stops18h 30m

Panama City Tocumen Intl

Thu 3/26

1:50 pm-9:52 am

2 stops19h 02m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 12/15

6:43 pm-1:47 pm

2 stops19h 04m

Panama City Tocumen Intl

Thu 3/12

1:50 pm-9:52 am

2 stops19h 02m

$480

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Tue 3/10

6:00 am-11:45 am

1 stop7h 45m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:35 pm

1 stop8h 25m

$570

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Tue 3/10

6:00 am-11:45 am

1 stop7h 45m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:35 pm

1 stop8h 25m

$680

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, May is the cheapest month to fly from Myrtle Beach to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $292. If you don’t want to visit Central America in May, then you should wait until August to fly from Myrtle Beach, when ticket prices are also cheap, with an average price of $399.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Myrtle Beach to Central America is on a Wednesday. Travelers who choose to depart for Central America on a Wednesday will often find tickets for as low as $321. On the other hand, Friday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $724.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Myrtle Beach to Central America flights are usually those with departure times in the evening. Our users have found flights to Central America in the evening for as low as $346. Try not to purchase tickets in the morning because they tend to be around $671. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Myrtle Beach to Central America flights?

You could potentially save up to 67% on your flight if you consider stops on a Myrtle Beach to Central America flight.

Cheap Myrtle Beach to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Central America

Direct flights

None
There are no direct flights from Myrtle Beach to Central America. There are no popular flight routes from Myrtle Beach to Central America.
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  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Central America?

    Prices for flights from Myrtle Beach Intl Airport to Central America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Central America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to Central America

Compare and see reviews for airlines that fly from Myrtle Beach to Central America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $267Free CancellationRating
6.3
8,112 reviews
Search Spirit Airlines flights
DeltaPriceFrom $378Free CancellationRating
7.9
7,995 reviews
Search Delta flights
American AirlinesPriceFrom $437Free CancellationRating
7.2
11,033 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Myrtle Beach to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Myrtle Beach to Central America with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Central America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Central America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Central America.

I’m not ready to book a flight from Myrtle Beach to Central America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Central America, momondo offers a useful price alert feature which will track prices for flights to Central America from Myrtle Beach and alert you when they change.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
Flights to San Joséfrom $138
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Flights to Guatemala Cityfrom $153
Flights to Panama Cityfrom $229
Flights to Managuafrom $215
Flights to Liberiafrom $224
Flights to San Pedro Sulafrom $110
Flights to Belize Cityfrom $213
Flights to Coxen Holefrom $330
Flights to Floresfrom $377
Flights to Bocas del Torofrom $866
Flights to Davidfrom $359