Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Myrtle Beach to Central America from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Myrtle Beach to Central America

Cheap round-trip flights

Logo
9:05 pm - 11:30 amMYR-SJO
16h 25m1 stop
Logo
7:30 am - 6:58 pmSJO-MYR
9h 28m1 stop
$311
Find Deal
Sun, Oct 19 - Sun, Oct 26
Logo
9:05 pm - 10:41 amMYR-SJO
15h 36m2 stops
Logo
7:30 am - 6:58 pmSJO-MYR
9h 28m1 stop
$338
Find Deal
Sun, Oct 19 - Sun, Oct 26
Spirit Airlines Logo
9:05 pm - 11:30 amMYR-SJO
16h 25m1 stop
Spirit Airlines Logo
12:35 pm - 11:57 pmSJO-MYR
33h 22m2 stops
$340Spirit Airlines
Find Deal
Sun, Oct 5 - Sat, Oct 11
Spirit Airlines Logo
9:05 pm - 11:22 amMYR-GUA
16h 17m1 stop
Spirit Airlines Logo
12:27 pm - 9:23 amGUA-MYR
18h 56m2 stops
$351Spirit Airlines
Find Deal
Fri, Oct 17 - Fri, Oct 24
Spirit Airlines Logo
9:05 pm - 11:22 amMYR-GUA
16h 17m1 stop
Spirit Airlines Logo
11:25 am - 5:49 pmGUA-MYR
28h 24m1 stop
$354Spirit Airlines
Find Deal
Fri, Oct 17 - Fri, Oct 24
Spirit Airlines Logo
11:46 am - 12:14 pmMYR-SJO
25h 28m1 stop
Spirit Airlines Logo
1:19 pm - 10:41 amSJO-MYR
20h 22m1 stop
$355Spirit Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
American Airlines Logo
6:03 am - 1:38 pmMYR-PTY
31h 35m2 stops
American Airlines Logo
4:37 pm - 1:29 pmPTY-MYR
20h 52m2 stops
$481American Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 11
American Airlines Logo
8:07 pm - 12:22 pmMYR-SJO
17h 15m1 stop
American Airlines Logo
1:33 pm - 11:55 pmSJO-MYR
9h 22m1 stop
$512American Airlines
Find Deal
Sat, Nov 8 - Sat, Nov 22
Delta Logo
6:00 am - 12:45 pmMYR-GUA
7h 45m1 stop
Delta Logo
2:10 pm - 11:35 pmGUA-MYR
8h 25m1 stop
$782Delta
Find Deal
Tue, Mar 3 - Fri, Mar 6
Delta Logo
7:00 am - 2:21 pmMYR-GUA
8h 21m1 stop
Delta Logo
3:57 pm - 11:35 pmGUA-MYR
6h 38m1 stop
$825Delta
Find Deal
Mon, Dec 22 - Mon, Jan 5

Spirit Airlines flights from Myrtle Beach to Central America

Our best Spirit Airlines deals on Myrtle Beach to Central America flight tickets
Spirit Airlines
Oct 5
MYR9:05 pmMyrtle Beach Intl
16h 25m
1 stop
SJO11:30 amSan José Juan Santamaria Intl
Oct 11
SJO12:35 pmSan José Juan Santamaria Intl
33h 22m
2 stops
MYR11:57 pmMyrtle Beach Intl
$340
Find similar
Spirit Airlines
Oct 17
MYR9:05 pmMyrtle Beach Intl
16h 17m
1 stop
GUA11:22 amGuatemala City La Aurora
Oct 24
GUA12:27 pmGuatemala City La Aurora
18h 56m
2 stops
MYR9:23 amMyrtle Beach Intl
$351
Find similar
Spirit Airlines
Oct 17
MYR9:05 pmMyrtle Beach Intl
16h 17m
1 stop
GUA11:22 amGuatemala City La Aurora
Oct 24
GUA11:25 amGuatemala City La Aurora
28h 24m
1 stop
MYR5:49 pmMyrtle Beach Intl
$354
Find similar

American Airlines flights from Myrtle Beach to Central America

Our best American Airlines deals on Myrtle Beach to Central America flight tickets
American Airlines
Nov 27
MYR6:03 amMyrtle Beach Intl
31h 35m
2 stops
PTY1:38 pmPanama City Tocumen Intl
Dec 11
PTY4:37 pmPanama City Tocumen Intl
20h 52m
2 stops
MYR1:29 pmMyrtle Beach Intl
$481
Find similar
American Airlines
Nov 8
MYR8:07 pmMyrtle Beach Intl
17h 15m
1 stop
SJO12:22 pmSan José Juan Santamaria Intl
Nov 22
SJO1:33 pmSan José Juan Santamaria Intl
9h 22m
1 stop
MYR11:55 pmMyrtle Beach Intl
$512
Find similar
American Airlines
Mar 1
MYR8:38 pmMyrtle Beach Intl
19h 36m
2 stops
BZE3:14 pmBelize City Philip S.W.Goldson
Mar 8
BZE3:40 pmBelize City Philip S.W.Goldson
18h 31m
2 stops
MYR12:11 pmMyrtle Beach Intl
$513
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 10/19

9:05 pm-11:30 am

1 stop16h 25m

San José Juan Santamaria Intl

Sun 10/26

7:30 am-6:58 pm

1 stop9h 28m

$311

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 10/19

9:05 pm-10:41 am

2 stops15h 36m

San José Juan Santamaria Intl

Sun 10/26

7:30 am-6:58 pm

1 stop9h 28m

$338

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sun 10/5

9:05 pm-11:30 am

1 stop16h 25m

San José Juan Santamaria Intl

Sat 10/11

12:35 pm-11:57 pm

2 stops33h 22m

$340

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Fri 10/17

9:05 pm-11:22 am

1 stop16h 17m

Guatemala City La Aurora

Fri 10/24

12:27 pm-9:23 am

2 stops18h 56m

$351

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Fri 10/17

9:05 pm-11:22 am

1 stop16h 17m

Guatemala City La Aurora

Fri 10/24

11:25 am-5:49 pm

1 stop28h 24m

$354

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Thu 11/6

11:46 am-12:14 pm

1 stop25h 28m

San José Juan Santamaria Intl

Thu 11/13

1:19 pm-10:41 am

1 stop20h 22m

$355

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 11/27

6:03 am-1:38 pm

2 stops31h 35m

Panama City Tocumen Intl

Thu 12/11

4:37 pm-1:29 pm

2 stops20h 52m

$481

Myrtle BeachSan José

MYR - SJO

MYRSJO

Myrtle Beach Intl

Sat 11/8

8:07 pm-12:22 pm

1 stop17h 15m

San José Juan Santamaria Intl

Sat 11/22

1:33 pm-11:55 pm

1 stop9h 22m

$512

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Tue 3/3

6:00 am-12:45 pm

1 stop7h 45m

Guatemala City La Aurora

Fri 3/6

2:10 pm-11:35 pm

1 stop8h 25m

$782

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Mon 12/22

7:00 am-2:21 pm

1 stop8h 21m

Guatemala City La Aurora

Mon 1/5

3:57 pm-11:35 pm

1 stop6h 38m

$825

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

How to get the cheapest flight ticket from Myrtle Beach to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, May is the cheapest month to fly from Myrtle Beach to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $292. If you don’t want to visit Central America in May, then you should wait until August to fly from Myrtle Beach, when ticket prices are also cheap, with an average price of $433.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Myrtle Beach to Central America is on a Wednesday. Travelers who choose to depart for Central America on a Wednesday will often find tickets for as low as $321. On the other hand, Friday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $724.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Myrtle Beach to Central America flights are usually those with departure times in the evening. Our users have found flights to Central America in the evening for as low as $346. Try not to purchase tickets in the morning because they tend to be around $671. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Myrtle Beach to Central America flights?

You could potentially save up to 51% on your flight if you consider stops on a Myrtle Beach to Central America flight.

Cheap Myrtle Beach to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Central America

Direct flights

None
There are no direct flights from Myrtle Beach to Central America. There are no popular flight routes from Myrtle Beach to Central America.
Search flight deals

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Central America?

    Prices for flights from Myrtle Beach Intl Airport to Central America were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Central America?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The required travel and health documents for your Central America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Central America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Myrtle Beach to Central America

Compare and see reviews for airlines that fly from Myrtle Beach to Central America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $267Free CancellationRating
6.3
8,016 reviews
Search Spirit Airlines flights
DeltaPriceFrom $428Free CancellationRating
7.9
7,977 reviews
Search Delta flights
American AirlinesPriceFrom $437Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Central America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Myrtle Beach to Central America. momondo saves you time and could save you money on your trip.

Can I find flights from Myrtle Beach to Central America with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Central America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Central America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Central America.

I’m not ready to book a flight from Myrtle Beach to Central America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Central America, momondo offers a useful price alert feature which will track prices for flights to Central America from Myrtle Beach and alert you when they change.

An easier way to manage your Central America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 9/9
Tue 9/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
Flights to San José, San José Provincefrom $139
Flights to San Salvadorfrom $102
Flights to Guatemala Cityfrom $137
Flights to Panama Cityfrom $269
Flights to Managuafrom $234
Flights to Liberiafrom $250
Flights to San Pedro Sulafrom $107
Flights to Belize Cityfrom $245
Flights to Coxen Holefrom $335
Flights to Floresfrom $437
Flights to Bocas del Torofrom $577
Flights to Davidfrom $296