What airlines fly to Spain?

British Airways, American Airlines and United Airlines are the top three most popular airlines that fly to Spain from Missouri according to our data. British Airways is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Spain. Keep in mind that there are 10 different airlines that fly to Spain on a routine basis, so you have a few additional options to choose from.

How long is the flight from Missouri to Spain?

Flight times from Missouri to Spain vary, but if you’re flying out of St. Louis and flying into Madrid (one of the most popular routes), then the duration is 11h 40m on average. Another popular route from Missouri to Spain is flying from Springfield to Madrid, which will take roughly 13h 20m. Keep in mind that layovers or delays could extend your travel time.

What is the cheapest airline that flies from Missouri to Spain?

British Airways, United Airlines, and Air Canada are the most popular carriers operating from Missouri to Spain

When did momondo last update prices for flights from Missouri to Spain?

Prices for flights from Missouri to Spain were last updated today.

How many operators does momondo search for flights from Missouri to Spain?

The number of operators available for flights from Missouri to Spain is 10 as of August 2026.

How old do you have to be to fly from Missouri to Spain?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Spain.

What documentation or ID do you need to fly to Spain?

The travel and health documents you'll need for your trip to Spain may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Spain. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$346 Cheap Flights from Missouri to Spain in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Spain

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:40 pm - 8:50 amSTL Lambert-St Louis-MAD Madrid Barajas

11h 10m1 stop Toronto Pearson Intl

1:30 pm - 8:00 pmMAD Madrid Barajas-STL Lambert-St Louis

13h 30m1 stop Toronto Pearson Intl

$658Air Canada

Mon, Sep 21 - Tue, Oct 6

2:40 pm - 8:50 amSTL Lambert-St Louis-MAD Madrid Barajas

11h 10m1 stop Toronto Pearson Intl

6:20 am - 8:00 pmMAD Madrid Barajas-STL Lambert-St Louis

20h 40m2 stops Brussels Bruxelles-National Toronto Pearson Intl

$669Air Canada

Mon, Sep 21 - Tue, Oct 6

3:14 pm - 6:40 pmMCI Kansas City-MAD Madrid Barajas

20h 26m2 stops Chicago O'Hare Intl Zurich

7:30 pm - 10:00 pmMAD Madrid Barajas-MCI Kansas City

33h 30m2 stops Zurich Chicago O'Hare Intl

$691SWISS

Tue, Oct 6 - Tue, Oct 20

3:14 pm - 6:40 pmMCI Kansas City-MAD Madrid Barajas

20h 26m2 stops Chicago O'Hare Intl Zurich

10:05 am - 10:00 pmMAD Madrid Barajas-MCI Kansas City

18h 55m2 stops Zurich Chicago O'Hare Intl

$691SWISS

Tue, Oct 6 - Tue, Oct 20

2:54 pm - 8:50 amSTL Lambert-St Louis-MAD Madrid Barajas

10h 56m1 stop Boston Logan Intl

12:00 pm - 11:58 pmMAD Madrid Barajas-STL Lambert-St Louis

18h 58m1 stop Chicago O'Hare Intl

$709Iberia

Wed, Jan 27 - Thu, Feb 18

9:12 am - 8:50 amMCI Kansas City-MAD Madrid Barajas

16h 38m1 stop Chicago O'Hare Intl

12:00 pm - 6:44 pmMAD Madrid Barajas-MCI Kansas City

13h 44m1 stop Chicago O'Hare Intl

$709Iberia

Sun, Nov 1 - Wed, Nov 11

12:10 pm - 6:50 amSTL Lambert-St Louis-MAD Madrid Barajas

11h 40m1 stop Montreal Pierre Elliott Trudeau Intl

12:45 pm - 3:43 pmMAD Madrid Barajas-STL Lambert-St Louis

33h 58m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$709United Airlines

Tue, Sep 29 - Fri, Oct 9

12:10 pm - 6:50 amSTL Lambert-St Louis-MAD Madrid Barajas

11h 40m1 stop Montreal Pierre Elliott Trudeau Intl

12:45 pm - 12:13 pmMAD Madrid Barajas-STL Lambert-St Louis

30h 28m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$709United Airlines

Sun, Oct 4 - Wed, Oct 14

3:30 pm - 12:15 pmSTL Lambert-St Louis-MAD Madrid Barajas

13h 45m1 stop Frankfurt am Main

6:00 am - 1:25 pmMAD Madrid Barajas-STL Lambert-St Louis

14h 25m1 stop Frankfurt am Main

$714Lufthansa

Tue, Sep 29 - Fri, Oct 9

3:30 pm - 4:00 pmSTL Lambert-St Louis-MAD Madrid Barajas

17h 30m1 stop Frankfurt am Main

6:00 am - 1:25 pmMAD Madrid Barajas-STL Lambert-St Louis

14h 25m1 stop Frankfurt am Main

$714Lufthansa

Mon, Sep 28 - Fri, Oct 9

Cheap last minute flights

Enter your travel dates to find the best prices.

12:10 pm - 6:50 amSTL Lambert-St Louis-MAD Madrid Barajas

11h 40m1 stop Montreal Pierre Elliott Trudeau Intl

1:30 pm - 12:02 pmMAD Madrid Barajas-STL Lambert-St Louis

29h 32m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$951United Airlines

Wed, Aug 12 - Wed, Aug 19

6:00 am - 6:50 amSTL Lambert-St Louis-MAD Madrid Barajas

17h 50m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:30 pm - 12:02 pmMAD Madrid Barajas-STL Lambert-St Louis

29h 32m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$956United Airlines

Wed, Aug 12 - Wed, Aug 19

9:35 pm - 8:05 pmSTL Lambert-St Louis-MAD Madrid Barajas

15h 30m1 stop London Heathrow

1:00 pm - 10:40 pmMAD Madrid Barajas-STL Lambert-St Louis

16h 40m1 stop Charlotte Douglas

$960British Airways

Wed, Aug 12 - Wed, Aug 19

12:59 pm - 11:00 amSTL Lambert-St Louis-VLC Valencia

15h 01m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:00 am - 6:42 pmVLC Valencia-STL Lambert-St Louis

19h 42m2 stops Zurich Montreal Pierre Elliott Trudeau Intl

$999Multiple Airlines

Thu, Aug 13 - Thu, Aug 20

3:14 pm - 6:40 pmMCI Kansas City-MAD Madrid Barajas

20h 26m2 stops Chicago O'Hare Intl Zurich

7:30 pm - 9:44 pmMAD Madrid Barajas-MCI Kansas City

33h 14m2 stops Zurich Chicago O'Hare Intl

$1,022SWISS

Sat, Aug 15 - Sun, Aug 23

7:39 pm - 8:20 amMCI Kansas City-MAD Madrid Barajas

29h 41m1 stop Chicago O'Hare Intl

11:45 am - 12:35 amMAD Madrid Barajas-MCI Kansas City

19h 50m1 stop Chicago O'Hare Intl

$1,054Iberia

Sat, Aug 15 - Sun, Aug 23

3:30 pm - 3:35 pmSTL Lambert-St Louis-BCN Barcelona-El Prat

17h 05m1 stop Frankfurt am Main

6:40 am - 11:38 pmBCN Barcelona-El Prat-STL Lambert-St Louis

23h 58m2 stops Frankfurt am Main Newark

$1,097Lufthansa

Fri, Aug 14 - Wed, Aug 19

6:54 pm - 6:15 pmSTL Lambert-St Louis-BCN Barcelona-El Prat

16h 21m2 stops Chicago O'Hare Intl Frankfurt am Main

8:00 am - 11:38 pmBCN Barcelona-El Prat-STL Lambert-St Louis

22h 38m2 stops Frankfurt am Main Newark

$1,102Lufthansa

Fri, Aug 14 - Wed, Aug 19

7:35 am - 9:35 amMCI Kansas City-MAD Madrid Barajas

19h 00m1 stop Philadelphia

3:25 pm - 10:10 pmMAD Madrid Barajas-MCI Kansas City

13h 45m1 stop Philadelphia

$1,224British Airways

Fri, Aug 14 - Sun, Aug 16

8:07 pm - 12:15 amSTL Lambert-St Louis-VLC Valencia

21h 08m2 stops Chicago O'Hare Intl Madrid Barajas

9:20 pm - 7:30 pmVLC Valencia-STL Lambert-St Louis

29h 10m1 stop London Heathrow

$1,246Iberia

Thu, Aug 13 - Thu, Aug 20

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Lufthansa flights from Missouri to Spain

Our best Lufthansa deals on Missouri to Spain flight tickets

Lufthansa

Oct 6

MCI6:39 pmKansas City

16h 01m

2 stops

MAD5:40 pmMadrid Barajas

Oct 20

MAD5:55 amMadrid Barajas

23h 05m

2 stops

MCI10:00 pmKansas City

$729

Lufthansa

Nov 12

STL6:50 pmLambert-St Louis

16h 00m

2 stops

MAD5:50 pmMadrid Barajas

Nov 20

MAD6:05 amMadrid Barajas

14h 40m

1 stop

STL1:45 pmLambert-St Louis

$767

Lufthansa

Sep 21

SGF6:37 pmSpringfield-Branson

11h 38m

1 stop

BCN1:15 pmBarcelona-El Prat

Sep 29

BCN3:15 pmBarcelona-El Prat

15h 03m

1 stop

SGF11:18 pmSpringfield-Branson

$825

KLM flights from Missouri to Spain

Our best KLM deals on Missouri to Spain flight tickets

KLM

Oct 21

STL2:38 pmLambert-St Louis

16h 02m

2 stops

MAD1:40 pmMadrid Barajas

Oct 25

MAD7:00 amMadrid Barajas

22h 54m

2 stops

STL11:54 pmLambert-St Louis

$783

KLM

Sep 25

STL6:54 pmLambert-St Louis

14h 36m

2 stops

BIO4:30 pmBilbao

Oct 2

BIO6:45 amBilbao

17h 25m

2 stops

STL5:10 pmLambert-St Louis

$850

KLM

Aug 13

MCI12:22 pmKansas City

16h 53m

1 stop

MAD12:15 pmMadrid Barajas

Aug 15

MAD1:05 pmMadrid Barajas

17h 53m

2 stops

MCI11:58 pmKansas City

$1,561

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Mon 9/21

2:40 pm-8:50 am

1 stop11h 10m

Madrid Barajas

Tue 10/6

1:30 pm-8:00 pm

1 stop13h 30m

$658

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Mon 9/21

2:40 pm-8:50 am

1 stop11h 10m

Madrid Barajas

Tue 10/6

6:20 am-8:00 pm

2 stops20h 40m

$669

Kansas CityMadrid

MCI Kansas City - MAD Madrid Barajas

MCIMAD

Kansas City

Tue 10/6

3:14 pm-6:40 pm

2 stops20h 26m

Madrid Barajas

Tue 10/20

7:30 pm-10:00 pm

2 stops33h 30m

$691

Kansas CityMadrid

MCI Kansas City - MAD Madrid Barajas

MCIMAD

Kansas City

Tue 10/6

3:14 pm-6:40 pm

2 stops20h 26m

Madrid Barajas

Tue 10/20

10:05 am-10:00 pm

2 stops18h 55m

$691

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Wed 1/27

2:54 pm-8:50 am

1 stop10h 56m

Madrid Barajas

Thu 2/18

12:00 pm-11:58 pm

1 stop18h 58m

$709

Kansas CityMadrid

MCI Kansas City - MAD Madrid Barajas

MCIMAD

Kansas City

Sun 11/1

9:12 am-8:50 am

1 stop16h 38m

Madrid Barajas

Wed 11/11

12:00 pm-6:44 pm

1 stop13h 44m

$709

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Tue 9/29

12:10 pm-6:50 am

1 stop11h 40m

Madrid Barajas

Fri 10/9

12:45 pm-3:43 pm

2 stops33h 58m

$709

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Sun 10/4

12:10 pm-6:50 am

1 stop11h 40m

Madrid Barajas

Wed 10/14

12:45 pm-12:13 pm

2 stops30h 28m

$709

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Tue 9/29

3:30 pm-12:15 pm

1 stop13h 45m

Madrid Barajas

Fri 10/9

6:00 am-1:25 pm

1 stop14h 25m

$714

St. LouisMadrid

STL Lambert-St Louis - MAD Madrid Barajas

STLMAD

Lambert-St Louis

Mon 9/28

3:30 pm-4:00 pm

1 stop17h 30m

Madrid Barajas

Fri 10/9

6:00 am-1:25 pm

1 stop14h 25m

$714

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Spain

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Spain?

If you don’t want to visit Spain in February, then you should wait until January to fly from Missouri, when ticket prices are also cheap, with an average price of $641.

How far in advance should I book a flight from Missouri to Spain?

You are more likely to see cheaper flights to Spain from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Spain for around $902 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Spain from Missouri for as low as $557 on momondo.

Can stopping save me money on Missouri to Spain flights?

You could potentially save up to 4% on your flight if you consider stops on a Missouri to Spain flight.

Cheap Missouri to Spain flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Spain

Fastest flight time	11h 10m
Direct flights	None

The fastest flight from Missouri to Spain takes 11h 10m

There are no direct flights from Missouri to Spain. There are no popular flight routes from Missouri to Spain.

Search flight deals

Frequently asked questions about flying from Missouri to Spain

When did momondo last update prices for flights from Missouri to Spain?
Prices for flights from Missouri to Spain were last updated today.
How many operators does momondo search for flights from Missouri to Spain?
The number of operators available for flights from Missouri to Spain is 10 as of August 2026.
How old do you have to be to fly from Missouri to Spain?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Spain.
What documentation or ID do you need to fly to Spain?
The travel and health documents you'll need for your trip to Spain may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Spain. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Missouri to Spain

Compare and see reviews for airlines that fly from Missouri to Spain with momondo

Airline	Rating	Free Cancellation	Price
Virgin Atlantic	PriceFrom $382	Free Cancellation	Rating 7.5 694 reviews	Search Virgin Atlantic flights
KLM	PriceFrom $433	Free Cancellation	Rating 7.8 1,557 reviews	Search KLM flights
Delta	PriceFrom $452	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights
Air France	PriceFrom $457	Free Cancellation	Rating 7.5 1,641 reviews	Search Air France flights
British Airways	PriceFrom $461	Free Cancellation	Rating 6.7 8,160 reviews	Search British Airways flights
Lufthansa	PriceFrom $480	Free Cancellation	Rating 6.8 8,182 reviews	Search Lufthansa flights
American Airlines	PriceFrom $485	Free Cancellation	Rating 7.1 11,915 reviews	Search American Airlines flights
Iberia	PriceFrom $488	Free Cancellation	Rating 7.0 3,261 reviews	Search Iberia flights
United Airlines	PriceFrom $490	Free Cancellation	Rating 7.4 10,115 reviews	Search United Airlines flights
Air Canada	PriceFrom $624	Free Cancellation	Rating 7.1 11,466 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Spain?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Spain from Missouri.

Can I find flights from Missouri to Spain with flexible booking policies on momondo?

momondo does allow users to show only those flights to Spain from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Spain?

momondo provides multiple filters to help you find the best flight to Spain from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Spain right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Spain from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.