Cheap flights from Missouri to Panama from $181
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama departing on 8/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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How to get the cheapest flight ticket from Missouri to Panama
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Panama?
The month of April is, on average, the cheapest month to fly to Panama from Missouri, with most prices found around $441. If you don’t want to visit Panama in April, then you should wait until October to fly from Missouri, when ticket prices are also cheap, with an average price of $469.
What is the cheapest day to depart on your flight to Panama?
According to our data, Tuesday is the cheapest day to fly to Panama from Missouri. The lowest ticket price found for a Tuesday departure recently was $509. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Missouri to Panama for around $607.
What is the cheapest time of day to depart on your flight to Panama?
In the afternoon is the cheapest time of day to fly from Missouri to Panama when you can find flight prices for as low as $512. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $691 per ticket.
How far in advance should I book a flight to Panama?
You are more likely to see cheaper flights to Panama from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $540 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Missouri for as low as $448 on momondo.
What is the cheapest airline that flies from Missouri to Panama?
United Airlines, American Airlines, and Copa Airlines are the most popular carriers operating from Missouri to Panama
What airlines fly to Panama?
United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from Missouri according to our data. United Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.
Cheap Missouri to Panama flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama
When did momondo last update prices for flights from Missouri to Panama?
Prices for flights from Missouri to Panama were last updated today.
How many operators does momondo search for flights from Missouri to Panama?
As of June 2025, there are 3 operators available to choose from for flights from Missouri to Panama.
How old do you have to be to fly from Missouri to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
Best airlines flying from Missouri to Panama
Compare and see reviews for airlines that fly from Missouri to Panama with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $373 | Free Cancellation | Rating 8.0 7,966 reviews | |||
| PriceFrom $394 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $397 | Free Cancellation | Rating 7.4 8,830 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from Missouri to Panama?
It is quick and easy to find Missouri to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.
Can I find flights from Missouri to Panama with flexible booking policies on momondo?
Yes. momondo enables you to select and highlight flights to Panama from Missouri with this policy.
How can momondo help me find flights from Missouri to Panama?
Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Missouri.
I’m not ready to book a flight from Missouri to Panama right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Missouri to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.