What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from Missouri according to our data. United Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Panama?

United Airlines and American Airlines are the most popular carriers operating from Missouri to Panama

How long is the flight from Missouri to Panama?

Flight times from Missouri to Panama vary, but if you’re flying out of Kansas City and flying into Panama City (one of the most popular routes), then the duration is 7h 05m on average. Another popular route from Missouri to Panama is flying from St. Louis to Panama City, which will take roughly 7h 22m. Keep in mind that layovers or delays could extend your travel time.

When did momondo last update prices for flights from Missouri to Panama?

Prices for flights from Missouri to Panama were last updated today.

How many operators does momondo search for flights from Missouri to Panama?

As of June 2026, there are 3 operators available to choose from for flights from Missouri to Panama.

How old do you have to be to fly from Missouri to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$236 Cheap Flights from Missouri to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 7:31 pm

MCI

PTY

13h 31m

1 stop

9:45 am - 11:59 pm

PTY

MCI

14h 14m

1 stop

$527United Airlines

Thu, Sep 10 - Mon, Sep 14

8:30 am - 6:37 pm

MCI

PTY

10h 07m

1 stop

9:45 am - 8:58 am

PTY

MCI

23h 13m

2 stops

$531United Airlines

Thu, Sep 10 - Mon, Sep 14

6:20 am - 6:37 pm

MCI

PTY

12h 17m

1 stop

3:30 pm - 2:09 pm

PTY

MCI

22h 39m

1 stop

$536United Airlines

Thu, Aug 20 - Mon, Aug 24

8:30 am - 4:12 pm

MCI

PTY

7h 42m

1 stop

7:55 am - 10:31 pm

PTY

MCI

14h 36m

1 stop

$557United Airlines

Thu, Jul 30 - Tue, Aug 4

5:37 pm - 2:14 pm

MCI

PTY

20h 37m

2 stops

3:30 pm - 2:20 pm

PTY

MCI

22h 50m

2 stops

$561United Airlines

Mon, Jul 27 - Mon, Aug 3

3:58 pm - 12:55 pm

MCI

PTY

20h 57m

1 stop

2:20 pm - 11:58 pm

PTY

MCI

9h 38m

1 stop

$570Delta

Sun, Aug 9 - Sun, Aug 16

3:58 pm - 12:55 pm

MCI

PTY

20h 57m

1 stop

2:30 pm - 7:01 pm

PTY

MCI

28h 31m

1 stop

$580Delta

Sun, Aug 9 - Sat, Aug 15

5:00 am - 12:39 pm

STL

PTY

7h 39m

1 stop

1:39 pm - 9:24 am

PTY

STL

19h 45m

2 stops

$609American Airlines

Sat, Aug 8 - Fri, Aug 14

11:35 am - 12:39 pm

STL

PTY

25h 04m

1 stop

1:39 pm - 9:24 am

PTY

STL

19h 45m

2 stops

$610American Airlines

Sat, Aug 8 - Fri, Aug 14

6:00 am - 12:56 pm

SGF

PTY

6h 56m

1 stop

3:30 pm - 10:32 pm

PTY

SGF

8h 02m

1 stop

$675Delta

Wed, Oct 28 - Thu, Nov 12

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Avianca flights from Missouri to Panama

Our best Avianca deals on Missouri to Panama flight tickets

Avianca

Aug 8

MCI12:30 pmKansas City

13h 25m

2 stops

PTY1:55 amPanama City Tocumen Intl

Aug 15

PTY5:30 amPanama City Tocumen Intl

14h 02m

2 stops

MCI7:32 pmKansas City

$631

Avianca

Aug 8

MCI5:45 pmKansas City

21h 10m

3 stops

PTY2:55 pmPanama City Tocumen Intl

Aug 15

PTY5:30 amPanama City Tocumen Intl

14h 02m

2 stops

MCI7:32 pmKansas City

$676

Avianca

Aug 8

MCI5:45 pmKansas City

16h 45m

2 stops

PTY10:30 amPanama City Tocumen Intl

Aug 16

PTY5:30 amPanama City Tocumen Intl

14h 02m

2 stops

MCI7:32 pmKansas City

$678

American Airlines flights from Missouri to Panama

Our best American Airlines deals on Missouri to Panama flight tickets

American Airlines

Jun 22

MCI7:52 pmKansas City

16h 21m

2 stops

PTY12:13 pmPanama City Tocumen Intl

Jun 24

PTY1:15 pmPanama City Tocumen Intl

22h 10m

2 stops

MCI11:25 amKansas City

$591

American Airlines

Aug 8

STL5:00 amLambert-St Louis

7h 39m

1 stop

PTY12:39 pmPanama City Tocumen Intl

Aug 14

PTY1:39 pmPanama City Tocumen Intl

19h 45m

2 stops

STL9:24 amLambert-St Louis

$609

American Airlines

Aug 8

STL11:35 amLambert-St Louis

25h 04m

1 stop

PTY12:39 pmPanama City Tocumen Intl

Aug 14

PTY1:39 pmPanama City Tocumen Intl

19h 45m

2 stops

STL9:24 amLambert-St Louis

$610

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 9/10

6:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Mon 9/14

9:45 am-11:59 pm

1 stop14h 14m

$527

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 9/10

8:30 am-6:37 pm

1 stop10h 07m

Panama City Tocumen Intl

Mon 9/14

9:45 am-8:58 am

2 stops23h 13m

$531

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 8/20

6:20 am-6:37 pm

1 stop12h 17m

Panama City Tocumen Intl

Mon 8/24

3:30 pm-2:09 pm

1 stop22h 39m

$536

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 7/30

8:30 am-4:12 pm

1 stop7h 42m

Panama City Tocumen Intl

Tue 8/4

7:55 am-10:31 pm

1 stop14h 36m

$557

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Mon 7/27

5:37 pm-2:14 pm

2 stops20h 37m

Panama City Tocumen Intl

Mon 8/3

3:30 pm-2:20 pm

2 stops22h 50m

$561

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Sun 8/9

3:58 pm-12:55 pm

1 stop20h 57m

Panama City Tocumen Intl

Sun 8/16

2:20 pm-11:58 pm

1 stop9h 38m

$570

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Sun 8/9

3:58 pm-12:55 pm

1 stop20h 57m

Panama City Tocumen Intl

Sat 8/15

2:30 pm-7:01 pm

1 stop28h 31m

$580

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sat 8/8

5:00 am-12:39 pm

1 stop7h 39m

Panama City Tocumen Intl

Fri 8/14

1:39 pm-9:24 am

2 stops19h 45m

$609

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sat 8/8

11:35 am-12:39 pm

1 stop25h 04m

Panama City Tocumen Intl

Fri 8/14

1:39 pm-9:24 am

2 stops19h 45m

$610

Quickest round-trip

SpringfieldPanama City

SGF - PTY

SGFPTY

Springfield-Branson

Wed 10/28

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Thu 11/12

3:30 pm-10:32 pm

1 stop8h 02m

$675

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of February is, on average, the cheapest month to fly to Panama from Missouri, with most prices found around $174. If you don’t want to visit Panama in February, then you should wait until January to fly from Missouri, when ticket prices are also cheap, with an average price of $362.

Can stopping save me money on Missouri to Panama flights?

You could potentially save up to 14% on your flight if you consider stops on a Missouri to Panama flight.

Cheap Missouri to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama

Fastest flight time	7h 05m
Direct flights	None

The fastest flight from Missouri to Panama takes 7h 05m

There are no direct flights from Missouri to Panama. There are no popular flight routes from Missouri to Panama.

Search flight deals

Frequently asked questions about flying from Missouri to Panama

When did momondo last update prices for flights from Missouri to Panama?
Prices for flights from Missouri to Panama were last updated today.
How many operators does momondo search for flights from Missouri to Panama?
As of June 2026, there are 3 operators available to choose from for flights from Missouri to Panama.
How old do you have to be to fly from Missouri to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 9,842 reviews	Search United Airlines flights
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.1 11,665 reviews	Search American Airlines flights
Delta	PriceFrom $452	Free Cancellation	Rating 7.9 8,404 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama?

It is quick and easy to find Missouri to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Missouri to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Missouri.

I’m not ready to book a flight from Missouri to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Popular cities in Panama

Flights to Panama Cityfrom $355

Flights to Bocas del Torofrom $678

Flights to Davidfrom $470

Flights to Changuinola

Cheap flights from Missouri to Panama from $236

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama departing on 11/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Avianca flights from Missouri to Panama

Our best Avianca deals on Missouri to Panama flight tickets

American Airlines flights from Missouri to Panama

Our best American Airlines deals on Missouri to Panama flight tickets

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How to get the cheapest flight ticket from Missouri to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Missouri to Panama flights?

What is the cheapest airline that flies from Missouri to Panama?

What airlines fly to Panama?

How long is the flight from Missouri to Panama?

Cheap Missouri to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama

Fastest flight time

Direct flights

Frequently asked questions about flying from Missouri to Panama

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Missouri flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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According to popular flight searches on momondo this year