How long is the flight from Missouri to Panama?

Flight times from Missouri to Panama vary, but if you’re flying out of St. Louis and flying into Panama City (one of the most popular routes), then the duration is 6h 55m on average. Another popular route from Missouri to Panama is flying from Kansas City to Panama City, which will take roughly 7h 14m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from Missouri according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Panama?

United Airlines, American Airlines, and Delta are the most popular carriers operating from Missouri to Panama

When did momondo last update prices for flights from Missouri to Panama?

Prices for flights from Missouri to Panama were last updated today.

How many operators does momondo search for flights from Missouri to Panama?

As of August 2026, there are 4 operators available to choose from for flights from Missouri to Panama.

How old do you have to be to fly from Missouri to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$290 Cheap Flights from Missouri to Panama in 2026

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Find the cheapest flights from Missouri to Panama

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 2:05 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 05m1 stop Atlanta Hartsfield-Jackson

3:30 pm - 11:58 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 28m1 stop Atlanta Hartsfield-Jackson

$597Delta

Mon, Nov 9 - Wed, Dec 9

6:42 pm - 1:55 pmMCI Kansas City-PTY Panama City Tocumen Intl

18h 13m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 10:26 pmPTY Panama City Tocumen Intl-MCI Kansas City

8h 06m1 stop Atlanta Hartsfield-Jackson

$597Delta

Sun, Jan 31 - Thu, Feb 4

8:22 am - 6:37 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 15m1 stop Houston George Bush Intcntl

10:00 am - 10:35 pmPTY Panama City Tocumen Intl-MCI Kansas City

12h 35m1 stop Houston George Bush Intcntl

$597United Airlines

Wed, Oct 14 - Wed, Oct 21

8:22 am - 6:37 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 15m1 stop Houston George Bush Intcntl

7:55 am - 10:30 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 35m1 stop Houston George Bush Intcntl

$597United Airlines

Wed, Oct 14 - Thu, Oct 29

7:24 pm - 2:13 pmMCI Kansas City-PTY Panama City Tocumen Intl

17h 49m2 stops Chicago O'Hare Intl Miami

3:13 pm - 11:11 amPTY Panama City Tocumen Intl-MCI Kansas City

20h 58m2 stops Miami Dallas/Fort Worth

$601American Airlines

Mon, Nov 9 - Wed, Dec 9

3:38 pm - 1:27 pmMCI Kansas City-PTY Panama City Tocumen Intl

20h 49m2 stops Washington, D.C. Reagan-National Miami

4:46 pm - 11:13 amPTY Panama City Tocumen Intl-MCI Kansas City

19h 27m2 stops Miami Dallas/Fort Worth

$606American Airlines

Wed, Jan 13 - Wed, Jan 27

11:50 am - 1:55 amMCI Kansas City-PTY Panama City Tocumen Intl

14h 05m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 7:46 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 16m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$663Avianca

Sat, Sep 26 - Sat, Oct 3

8:30 am - 1:55 amMCI Kansas City-PTY Panama City Tocumen Intl

17h 25m2 stops Houston George Bush Intcntl San Salvador El Salvador Intl

5:30 am - 10:35 pmPTY Panama City Tocumen Intl-MCI Kansas City

17h 05m2 stops San Salvador El Salvador Intl Houston George Bush Intcntl

$696Multiple Airlines

Thu, Sep 10 - Mon, Sep 14

11:00 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 38m1 stop Houston George Bush Intcntl

4:41 pm - 10:06 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

30h 25m1 stop Houston George Bush Intcntl

$808Copa Airlines

Fri, Jan 8 - Sun, Jan 17

6:15 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 23m1 stop Houston George Bush Intcntl

4:41 pm - 10:06 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

30h 25m1 stop Houston George Bush Intcntl

$829Copa Airlines

Sat, Jan 9 - Sun, Jan 17

Cheap last minute flights

Enter your travel dates to find the best prices.

6:20 am - 2:14 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 54m1 stop Houston George Bush Intcntl

9:45 am - 11:59 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 14m1 stop Newark

$726United Airlines

Fri, Aug 14 - Mon, Aug 17

6:00 am - 7:31 pmMCI Kansas City-PTY Panama City Tocumen Intl

13h 31m2 stops Chicago O'Hare Intl Newark

3:30 pm - 10:25 amPTY Panama City Tocumen Intl-MCI Kansas City

18h 55m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$730United Airlines

Fri, Aug 14 - Mon, Aug 17

6:00 am - 7:31 pmMCI Kansas City-PTY Panama City Tocumen Intl

13h 31m2 stops Chicago O'Hare Intl Newark

9:45 am - 11:59 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 14m1 stop Newark

$730United Airlines

Fri, Aug 14 - Mon, Aug 17

5:01 am - 12:39 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 38m1 stop Miami

1:39 pm - 1:32 pmPTY Panama City Tocumen Intl-MCI Kansas City

23h 53m2 stops Miami Philadelphia

$735American Airlines

Fri, Aug 14 - Mon, Aug 17

6:20 am - 2:14 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 54m1 stop Houston George Bush Intcntl

10:00 am - 10:35 pmPTY Panama City Tocumen Intl-MCI Kansas City

12h 35m1 stop Houston George Bush Intcntl

$746United Airlines

Sun, Aug 16 - Tue, Aug 18

5:01 am - 12:39 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 38m1 stop Miami

1:39 pm - 1:38 pmPTY Panama City Tocumen Intl-MCI Kansas City

23h 59m2 stops Miami Dallas/Fort Worth

$755American Airlines

Fri, Aug 14 - Mon, Aug 17

5:01 am - 12:39 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 38m1 stop Miami

1:39 pm - 8:40 amPTY Panama City Tocumen Intl-MCI Kansas City

19h 01m2 stops Miami Chicago O'Hare Intl

$777American Airlines

Fri, Aug 14 - Mon, Aug 17

12:10 pm - 1:55 amMCI Kansas City-PTY Panama City Tocumen Intl

13h 45m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 10:35 pmPTY Panama City Tocumen Intl-MCI Kansas City

17h 05m2 stops San Salvador El Salvador Intl Houston George Bush Intcntl

$816Multiple Airlines

Fri, Aug 14 - Mon, Aug 17

6:37 pm - 9:15 amSGF Springfield-Branson-PTY Panama City Tocumen Intl

14h 38m2 stops Chicago O'Hare Intl Bogotá El Dorado

5:30 am - 4:11 pmPTY Panama City Tocumen Intl-SGF Springfield-Branson

10h 41m2 stops San Salvador El Salvador Intl Houston George Bush Intcntl

$838Multiple Airlines

Mon, Aug 17 - Fri, Aug 21

8:40 am - 1:55 amSTL Lambert-St Louis-PTY Panama City Tocumen Intl

17h 15m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

11:25 am - 9:39 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

22h 14m3 stops San José Juan Santamaria Intl Guatemala City La Aurora Washington, D.C. Dulles Intl

$2,961Avianca

Sat, Aug 15 - Mon, Sep 14

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American Airlines flights from Missouri to Panama

Our best American Airlines deals on Missouri to Panama flight tickets

American Airlines

Jan 13

MCI3:38 pmKansas City

20h 49m

2 stops

PTY1:27 pmPanama City Tocumen Intl

Jan 27

PTY4:46 pmPanama City Tocumen Intl

19h 27m

2 stops

MCI11:13 amKansas City

$606

American Airlines

Jan 13

MCI4:13 pmKansas City

20h 14m

2 stops

PTY1:27 pmPanama City Tocumen Intl

Jan 27

PTY2:27 pmPanama City Tocumen Intl

22h 22m

2 stops

MCI11:49 amKansas City

$616

American Airlines

Jan 13

MCI11:40 amKansas City

24h 47m

1 stop

PTY1:27 pmPanama City Tocumen Intl

Jan 27

PTY2:27 pmPanama City Tocumen Intl

22h 22m

2 stops

MCI11:49 amKansas City

$621

United Airlines flights from Missouri to Panama

Our best United Airlines deals on Missouri to Panama flight tickets

United Airlines

Oct 14

MCI8:22 amKansas City

10h 15m

1 stop

PTY6:37 pmPanama City Tocumen Intl

Oct 29

PTY7:55 amPanama City Tocumen Intl

14h 35m

1 stop

MCI10:30 pmKansas City

$597

United Airlines

Oct 14

MCI6:19 amKansas City

7h 55m

1 stop

PTY2:14 pmPanama City Tocumen Intl

Oct 21

PTY3:30 pmPanama City Tocumen Intl

18h 56m

2 stops

MCI10:26 amKansas City

$601

United Airlines

Nov 15

MCI8:30 amKansas City

29h 15m

1 stop

PTY2:45 pmPanama City Tocumen Intl

Nov 18

PTY4:41 pmPanama City Tocumen Intl

18h 25m

1 stop

MCI10:06 amKansas City

$607

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Mon 11/9

6:00 am-2:05 pm

1 stop7h 05m

Panama City Tocumen Intl

Wed 12/9

3:30 pm-11:58 pm

1 stop9h 28m

$597

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sun 1/31

6:42 pm-1:55 pm

1 stop18h 13m

Panama City Tocumen Intl

Thu 2/4

3:20 pm-10:26 pm

1 stop8h 06m

$597

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Wed 10/14

8:22 am-6:37 pm

1 stop10h 15m

Panama City Tocumen Intl

Wed 10/21

10:00 am-10:35 pm

1 stop12h 35m

$597

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Wed 10/14

8:22 am-6:37 pm

1 stop10h 15m

Panama City Tocumen Intl

Thu 10/29

7:55 am-10:30 pm

1 stop14h 35m

$597

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Mon 11/9

7:24 pm-2:13 pm

2 stops17h 49m

Panama City Tocumen Intl

Wed 12/9

3:13 pm-11:11 am

2 stops20h 58m

$601

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Wed 1/13

3:38 pm-1:27 pm

2 stops20h 49m

Panama City Tocumen Intl

Wed 1/27

4:46 pm-11:13 am

2 stops19h 27m

$606

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 9/26

11:50 am-1:55 am

2 stops14h 05m

Panama City Tocumen Intl

Sat 10/3

5:30 am-7:46 pm

2 stops14h 16m

$663

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Thu 9/10

8:30 am-1:55 am

2 stops17h 25m

Panama City Tocumen Intl

Mon 9/14

5:30 am-10:35 pm

2 stops17h 05m

$696

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Fri 1/8

11:00 am-7:38 pm

1 stop7h 38m

Panama City Tocumen Intl

Sun 1/17

4:41 pm-10:06 pm

1 stop30h 25m

$808

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Sat 1/9

6:15 am-7:38 pm

1 stop12h 23m

Panama City Tocumen Intl

Sun 1/17

4:41 pm-10:06 pm

1 stop30h 25m

$829

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from Missouri, with most prices found around $522. If you don’t want to visit Panama in April, then you should wait until November to fly from Missouri, when ticket prices are also cheap, with an average price of $529.

Can stopping save me money on Missouri to Panama flights?

You could potentially save up to 31% on your flight if you consider stops on a Missouri to Panama flight.

Cheap Missouri to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama

Fastest flight time	6h 55m
Direct flights	None

The fastest flight from Missouri to Panama takes 6h 55m

There are no direct flights from Missouri to Panama. There are no popular flight routes from Missouri to Panama.

Search flight deals

Frequently asked questions about flying from Missouri to Panama

When did momondo last update prices for flights from Missouri to Panama?
Prices for flights from Missouri to Panama were last updated today.
How many operators does momondo search for flights from Missouri to Panama?
As of August 2026, there are 4 operators available to choose from for flights from Missouri to Panama.
How old do you have to be to fly from Missouri to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.1 11,929 reviews	Search American Airlines flights
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 10,108 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $446	Free Cancellation	Rating 7.6 1,560 reviews	Search Copa Airlines flights
Delta	PriceFrom $461	Free Cancellation	Rating 7.8 8,502 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama?

It is quick and easy to find Missouri to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Missouri to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Missouri.

I’m not ready to book a flight from Missouri to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Flights to Panama Cityfrom $453

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Cheap flights from Missouri to Panama from $290

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama departing on 10/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Missouri to Panama

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United Airlines flights from Missouri to Panama

Our best United Airlines deals on Missouri to Panama flight tickets

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How to get the cheapest flight ticket from Missouri to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Missouri to Panama flights?

What is the cheapest airline that flies from Missouri to Panama?

What airlines fly to Panama?

How long is the flight from Missouri to Panama?

Cheap Missouri to Panama flight deals and tips

Fastest flight time

Direct flights

Frequently asked questions about flying from Missouri to Panama

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Missouri flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

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Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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Explore popular destinations other users love

According to popular flight searches on momondo this year