How long is the flight from Missouri to Panama?

Flight times from Missouri to Panama vary, but if you’re flying out of Kansas City and flying into Panama City (one of the most popular routes), then the duration is 7h 17m on average. Another popular route from Missouri to Panama is flying from St. Louis to Panama City, which will take roughly 7h 59m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from Missouri according to our data. United Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Panama?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Missouri to Panama

When did momondo last update prices for flights from Missouri to Panama?

Prices for flights from Missouri to Panama were last updated today.

How many operators does momondo search for flights from Missouri to Panama?

As of October 2026, there are 4 operators available to choose from for flights from Missouri to Panama.

How old do you have to be to fly from Missouri to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$271 Cheap Flights from Missouri to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Panama

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 2:45 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 45m1 stop Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

11h 55m1 stop Houston George Bush Intcntl

$607United Airlines

Thu, Dec 10 - Mon, Dec 14

6:15 am - 5:12 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

9h 57m1 stop Houston George Bush Intcntl

8:55 am - 6:38 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

10h 43m1 stop Houston George Bush Intcntl

$607United Airlines

Mon, Feb 1 - Wed, Feb 17

3:45 pm - 1:26 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

20h 41m2 stops Dallas/Fort Worth Miami

4:04 pm - 9:19 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

18h 15m2 stops Miami Dallas/Fort Worth

$611American Airlines

Mon, Feb 1 - Wed, Feb 17

3:00 pm - 1:26 pmMCI Kansas City-PTY Panama City Tocumen Intl

21h 26m2 stops Charlotte Douglas Miami

2:39 pm - 11:57 pmPTY Panama City Tocumen Intl-MCI Kansas City

10h 18m1 stop Miami

$611American Airlines

Mon, Feb 8 - Fri, Feb 19

11:33 am - 2:10 amMCI Kansas City-PTY Panama City Tocumen Intl

14h 37m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 7:55 pmPTY Panama City Tocumen Intl-MCI Kansas City

15h 25m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$669Multiple Airlines

Sat, Oct 31 - Sat, Nov 7

11:33 am - 2:10 amMCI Kansas City-PTY Panama City Tocumen Intl

13h 37m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 7:55 pmPTY Panama City Tocumen Intl-MCI Kansas City

15h 25m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$678Avianca

Sat, Nov 14 - Sat, Nov 21

5:40 am - 2:03 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 23m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:56 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 27m1 stop Atlanta Hartsfield-Jackson

$706Delta

Fri, Dec 4 - Mon, Dec 7

5:40 am - 2:03 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 23m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:56 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 27m1 stop Atlanta Hartsfield-Jackson

$706Delta

Fri, Dec 4 - Tue, Dec 8

6:30 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 32m1 stop Newark

8:55 am - 10:13 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 18m1 stop Houston George Bush Intcntl

$869Copa Airlines

Wed, Jan 27 - Tue, Feb 2

6:30 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 32m1 stop Newark

8:55 am - 10:13 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 18m1 stop Houston George Bush Intcntl

$878Copa Airlines

Wed, Jan 27 - Tue, Feb 2

Cheap last minute flights

Enter your travel dates to find the best prices.

8:22 am - 6:37 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 15m1 stop Houston George Bush Intcntl

3:41 pm - 10:06 amPTY Panama City Tocumen Intl-MCI Kansas City

18h 25m1 stop Houston George Bush Intcntl

$731United Airlines

Tue, Oct 6 - Sun, Oct 25

6:39 pm - 2:14 pmMCI Kansas City-PTY Panama City Tocumen Intl

19h 35m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

3:41 pm - 10:06 amPTY Panama City Tocumen Intl-MCI Kansas City

18h 25m1 stop Houston George Bush Intcntl

$736United Airlines

Tue, Oct 6 - Sun, Oct 25

2:20 pm - 1:02 pmMCI Kansas City-PTY Panama City Tocumen Intl

22h 42m2 stops Dallas/Fort Worth Miami

2:02 pm - 11:16 amPTY Panama City Tocumen Intl-MCI Kansas City

21h 14m2 stops Miami Philadelphia

$746American Airlines

Tue, Oct 6 - Sun, Oct 25

5:00 am - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 16m1 stop Miami

2:02 pm - 9:59 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

7h 57m1 stop Miami

$764American Airlines

Fri, Oct 2 - Thu, Oct 8

5:00 am - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 16m1 stop Miami

2:02 pm - 10:50 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

20h 48m2 stops Miami Chicago O'Hare Intl

$768American Airlines

Fri, Oct 2 - Thu, Oct 8

5:45 pm - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

18h 31m2 stops Philadelphia Miami

2:02 pm - 10:50 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

20h 48m2 stops Miami Chicago O'Hare Intl

$802American Airlines

Fri, Oct 2 - Thu, Oct 8

6:15 am - 2:14 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 59m1 stop Houston George Bush Intcntl

9:45 am - 9:09 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

11h 24m1 stop Newark

$941United Airlines

Mon, Oct 5 - Wed, Oct 7

6:15 am - 2:14 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 59m1 stop Houston George Bush Intcntl

3:30 pm - 12:13 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

20h 43m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$941United Airlines

Mon, Oct 5 - Wed, Oct 7

2:29 pm - 12:35 amSTL Lambert-St Louis-PTY Panama City Tocumen Intl

34h 06m3 stops Atlanta Hartsfield-Jackson Orlando Bogotá El Dorado

3:10 pm - 11:13 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

32h 03m2 stops Bogotá El Dorado Orlando

$1,282Multiple Airlines

Mon, Oct 5 - Wed, Oct 7

5:46 pm - 2:55 pmMCI Kansas City-PTY Panama City Tocumen Intl

21h 09m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

4:10 pm - 7:55 pmPTY Panama City Tocumen Intl-MCI Kansas City

27h 45m2 stops Bogotá El Dorado Washington, D.C. Dulles Intl

$1,476Avianca

Tue, Oct 6 - Sun, Oct 25

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GOL flights from Missouri to Panama

Our best GOL deals on Missouri to Panama flight tickets

GOL

Nov 22

SGF6:46 pmSpringfield-Branson

18h 48m

2 stops

PTY2:34 pmPanama City Tocumen Intl

Nov 29

PTY3:34 pmPanama City Tocumen Intl

27h 27m

2 stops

SGF6:01 pmSpringfield-Branson

$1,026

GOL

Nov 22

SGF4:42 pmSpringfield-Branson

20h 52m

2 stops

PTY2:34 pmPanama City Tocumen Intl

Nov 28

PTY3:34 pmPanama City Tocumen Intl

27h 27m

2 stops

SGF6:01 pmSpringfield-Branson

$1,032

Delta flights from Missouri to Panama

Our best Delta deals on Missouri to Panama flight tickets

Delta

Dec 4

MCI5:40 amKansas City

7h 23m

1 stop

PTY2:03 pmPanama City Tocumen Intl

Dec 7

PTY3:29 pmPanama City Tocumen Intl

9h 27m

1 stop

MCI11:56 pmKansas City

$706

Delta

Oct 17

MCI5:40 amKansas City

7h 19m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Oct 24

PTY2:24 pmPanama City Tocumen Intl

9h 32m

1 stop

MCI11:56 pmKansas City

$795

Delta

Oct 12

STL6:00 amLambert-St Louis

6h 59m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Oct 26

PTY2:24 pmPanama City Tocumen Intl

9h 30m

1 stop

STL11:54 pmLambert-St Louis

$1,706

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Thu 12/10

6:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Mon 12/14

11:35 am-10:30 pm

1 stop11h 55m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 2/1

6:15 am-5:12 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 2/17

8:55 am-6:38 pm

1 stop10h 43m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 2/1

3:45 pm-1:26 pm

2 stops20h 41m

Panama City Tocumen Intl

Wed 2/17

4:04 pm-9:19 am

2 stops18h 15m

$611

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Mon 2/8

3:00 pm-1:26 pm

2 stops21h 26m

Panama City Tocumen Intl

Fri 2/19

2:39 pm-11:57 pm

1 stop10h 18m

$611

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 10/31

11:33 am-2:10 am

2 stops14h 37m

Panama City Tocumen Intl

Sat 11/7

5:30 am-7:55 pm

2 stops15h 25m

$669

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 11/14

11:33 am-2:10 am

2 stops13h 37m

Panama City Tocumen Intl

Sat 11/21

5:30 am-7:55 pm

2 stops15h 25m

$678

Quickest round-trip

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Fri 12/4

5:40 am-2:03 pm

1 stop7h 23m

Panama City Tocumen Intl

Mon 12/7

3:29 pm-11:56 pm

1 stop9h 27m

$706

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Fri 12/4

5:40 am-2:03 pm

1 stop7h 23m

Panama City Tocumen Intl

Tue 12/8

3:29 pm-11:56 pm

1 stop9h 27m

$706

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Wed 1/27

6:30 am-8:02 pm

1 stop12h 32m

Panama City Tocumen Intl

Tue 2/2

8:55 am-10:13 pm

1 stop14h 18m

$869

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Wed 1/27

6:30 am-8:02 pm

1 stop12h 32m

Panama City Tocumen Intl

Tue 2/2

8:55 am-10:13 pm

1 stop14h 18m

$878

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Missouri, with most prices found around $510. If you don’t want to visit Panama in November, then you should wait until April to fly from Missouri, when ticket prices are also cheap, with an average price of $529.

Can stopping save me money on Missouri to Panama flights?

You could potentially save up to 46% on your flight if you consider stops on a Missouri to Panama flight.

Cheap Missouri to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama

Best Price Found	$271
Fastest flight time	7h 17m
Direct flights	None

The best one-way flight to Panama from Missouri in the past 72 hours is $271. The best round-trip flight deal from Missouri to Panama found on momondo in the last 72 hours is $607.

The fastest flight from Missouri to Panama takes 7h 17m

There are no direct flights from Missouri to Panama. There are no popular flight routes from Missouri to Panama.

Search flight deals

Frequently asked questions about flying from Missouri to Panama

When did momondo last update prices for flights from Missouri to Panama?
Prices for flights from Missouri to Panama were last updated today.
How many operators does momondo search for flights from Missouri to Panama?
As of October 2026, there are 4 operators available to choose from for flights from Missouri to Panama.
How old do you have to be to fly from Missouri to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.0 12,103 reviews	Search American Airlines flights
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 10,271 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $446	Free Cancellation	Rating 7.6 1,543 reviews	Search Copa Airlines flights
Delta	PriceFrom $461	Free Cancellation	Rating 7.8 8,620 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama?

It is quick and easy to find Missouri to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Missouri to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Missouri.

I’m not ready to book a flight from Missouri to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Missouri to Panama from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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GOL flights from Missouri to Panama

Our best GOL deals on Missouri to Panama flight tickets

Delta flights from Missouri to Panama

Our best Delta deals on Missouri to Panama flight tickets

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How to get the cheapest flight ticket from Missouri to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Missouri to Panama flights?

What is the cheapest airline that flies from Missouri to Panama?

What airlines fly to Panama?

How long is the flight from Missouri to Panama?

Cheap Missouri to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Missouri to Panama

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Missouri flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

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According to popular flight searches on momondo this year