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Cheap flights from Missouri to Panama from $201

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama departing on 5/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:15 am - 6:37 pm
MCI
-
PTY
12h 22m
1 stop
United Airlines Logo
3:30 pm - 10:03 am
PTY
-
MCI
18h 33m
1 stop
$467United Airlines
mar., may. 19 - mié., may. 27
United Airlines Logo
7:55 pm - 7:31 pm
MCI
-
PTY
23h 36m
2 stops
United Airlines Logo
3:30 pm - 9:07 am
PTY
-
MCI
17h 37m
2 stops
$471United Airlines
lun., jun. 8 - jue., jun. 11
United Airlines Logo
8:30 am - 2:14 pm
MCI
-
PTY
29h 44m
1 stop
United Airlines Logo
3:30 pm - 2:17 pm
PTY
-
MCI
22h 47m
2 stops
$480United Airlines
dom., ago. 16 - jue., ago. 20
American Airlines Logo
3:32 pm - 12:46 pm
MCI
-
PTY
21h 14m
2 stops
American Airlines Logo
1:14 pm - 1:07 pm
PTY
-
MCI
23h 53m
2 stops
$481American Airlines
mar., may. 19 - mié., may. 27
Copa Airlines Logo
6:00 am - 7:31 pm
MCI
-
PTY
13h 31m
1 stop
Copa Airlines Logo
3:30 pm - 9:07 am
PTY
-
MCI
17h 37m
2 stops
$483Copa Airlines
lun., jun. 8 - jue., jun. 11
United Airlines Logo
8:30 am - 2:14 pm
MCI
-
PTY
29h 44m
1 stop
United Airlines Logo
3:30 pm - 10:05 am
PTY
-
MCI
18h 35m
1 stop
$484United Airlines
dom., ago. 16 - jue., ago. 20
American Airlines Logo
5:24 am - 12:46 pm
STL
-
PTY
7h 22m
1 stop
American Airlines Logo
1:49 pm - 8:27 am
PTY
-
STL
18h 38m
2 stops
$497American Airlines
mié., may. 6 - mié., may. 13
United Airlines Logo
6:16 am - 2:14 pm
MCI
-
PTY
7h 58m
1 stop
United Airlines Logo
7:55 am - 4:47 pm
PTY
-
MCI
8h 52m
1 stop
$504United Airlines
lun., jun. 8 - jue., jun. 11
Delta Logo
6:00 am - 1:02 pm
STL
-
PTY
7h 02m
1 stop
Delta Logo
2:27 pm - 11:35 pm
PTY
-
STL
9h 08m
1 stop
$505Delta
mié., abr. 29 - mié., may. 6
Delta Logo
4:41 pm - 1:02 pm
STL
-
PTY
20h 21m
1 stop
Delta Logo
2:15 pm - 9:44 am
PTY
-
STL
19h 29m
1 stop
$521Delta
dom., may. 3 - mar., may. 19

Delta flights from Missouri to Panama

Our best Delta deals on Missouri to Panama flight tickets
Delta
Apr 29
STL6:00 amLambert-St Louis
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 6
PTY2:27 pmPanama City Tocumen Intl
9h 08m
1 stop
STL11:35 pmLambert-St Louis
$505
Delta
Apr 13
MCI5:40 amKansas City
7h 22m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 23
PTY2:27 pmPanama City Tocumen Intl
9h 23m
1 stop
MCI11:50 pmKansas City
$517
Delta
May 3
STL4:41 pmLambert-St Louis
20h 21m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 19
PTY2:15 pmPanama City Tocumen Intl
19h 29m
1 stop
STL9:44 amLambert-St Louis
$521

American Airlines flights from Missouri to Panama

Our best American Airlines deals on Missouri to Panama flight tickets
American Airlines
May 19
MCI3:32 pmKansas City
21h 14m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 27
PTY1:14 pmPanama City Tocumen Intl
23h 53m
2 stops
MCI1:07 pmKansas City
$481
American Airlines
May 6
STL5:24 amLambert-St Louis
7h 22m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 13
PTY1:49 pmPanama City Tocumen Intl
8h 35m
1 stop
STL10:24 pmLambert-St Louis
$497
American Airlines
May 19
MCI3:32 pmKansas City
21h 14m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 27
PTY1:14 pmPanama City Tocumen Intl
23h 53m
2 stops
MCI1:07 pmKansas City
$503

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated marzo 28, 2026.
Use the filters below to find and compare flights from Missouri to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

mar. 5/19

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

mié. 5/27

3:30 pm-10:03 am

1 stop18h 33m

$467

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

lun. 6/8

7:55 pm-7:31 pm

2 stops23h 36m

Panama City Tocumen Intl

jue. 6/11

3:30 pm-9:07 am

2 stops17h 37m

$471

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

dom. 8/16

8:30 am-2:14 pm

1 stop29h 44m

Panama City Tocumen Intl

jue. 8/20

3:30 pm-2:17 pm

2 stops22h 47m

$480

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

mar. 5/19

3:32 pm-12:46 pm

2 stops21h 14m

Panama City Tocumen Intl

mié. 5/27

1:14 pm-1:07 pm

2 stops23h 53m

$481

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

lun. 6/8

6:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

jue. 6/11

3:30 pm-9:07 am

2 stops17h 37m

$483

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

dom. 8/16

8:30 am-2:14 pm

1 stop29h 44m

Panama City Tocumen Intl

jue. 8/20

3:30 pm-10:05 am

1 stop18h 35m

$484

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mié. 5/6

5:24 am-12:46 pm

1 stop7h 22m

Panama City Tocumen Intl

mié. 5/13

1:49 pm-8:27 am

2 stops18h 38m

$497

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

lun. 6/8

6:16 am-2:14 pm

1 stop7h 58m

Panama City Tocumen Intl

jue. 6/11

7:55 am-4:47 pm

1 stop8h 52m

$504
Quickest round-trip

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mié. 4/29

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

mié. 5/6

2:27 pm-11:35 pm

1 stop9h 08m

$505

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

dom. 5/3

4:41 pm-1:02 pm

1 stop20h 21m

Panama City Tocumen Intl

mar. 5/19

2:15 pm-9:44 am

1 stop19h 29m

$521

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Missouri to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from Missouri, with most prices found around $459. If you don’t want to visit Panama in April, then you should wait until May to fly from Missouri, when ticket prices are also cheap, with an average price of $510.

Can stopping save me money on Missouri to Panama flights?

You could potentially save up to 9% on your flight if you consider stops on a Missouri to Panama flight.

Cheap Missouri to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama

Fastest flight time

6h 56m

Direct flights

None
The fastest flight from Missouri to Panama takes 6h 56m
There are no direct flights from Missouri to Panama. There are no popular flight routes from Missouri to Panama.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Panama?

    Prices for flights from Missouri to Panama were last updated today.

  • How many operators does momondo search for flights from Missouri to Panama?

  • How old do you have to be to fly from Missouri to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama

Compare and see reviews for airlines that fly from Missouri to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
7.9
8,356 reviews
Search Delta flights
United AirlinesPriceFrom $393Free CancellationRating
7.4
9,499 reviews
Search United Airlines flights
American AirlinesPriceFrom $393Free CancellationRating
7.1
11,520 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama?

It is quick and easy to find Missouri to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Missouri to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Missouri.

I’m not ready to book a flight from Missouri to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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