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Cheap flights from Mississippi to Chicago from $81

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Chicago departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
11:44 am - 7:41 pm
MEM
-
ORD
7h 57m1 stop
Multiple Airlines Logo
2:30 pm - 1:04 pm
ORD
-
MEM
22h 34m1 stop
$181Multiple Airlines
Sat, Jan 17 - Sun, Jan 18
Multiple Airlines Logo
11:44 am - 10:41 am
MEM
-
ORD
22h 57m1 stop
Multiple Airlines Logo
5:32 pm - 7:28 pm
ORD
-
MEM
25h 56m1 stop
$186Multiple Airlines
Wed, Jan 21 - Wed, Jan 28
Multiple Airlines Logo
11:44 am - 10:41 am
MEM
-
ORD
22h 57m1 stop
Multiple Airlines Logo
5:32 pm - 7:28 pm
ORD
-
MEM
25h 56m1 stop
$190Multiple Airlines
Wed, Jan 21 - Sat, Jan 24
United Airlines Logo
7:30 am - 9:27 am
MEM
-
ORD
1h 57mnonstop
United Airlines Logo
3:35 pm - 5:26 pm
ORD
-
MEM
1h 51mnonstop
$193United Airlines
Wed, Jan 21 - Wed, Jan 28
Frontier Logo
5:55 pm - 10:39 pm
MEM
-
ORD
4h 44m1 stop
Frontier Logo
5:50 am - 5:00 pm
ORD
-
MEM
11h 10m1 stop
$197Frontier
Thu, Jan 8 - Sun, Jan 11
American Airlines Logo
10:41 am - 3:55 pm
MOB
-
ORD
5h 14m1 stop
American Airlines Logo
5:00 am - 11:47 am
ORD
-
MOB
6h 47m1 stop
$211American Airlines
Wed, Mar 18 - Wed, Apr 15
Delta Logo
7:17 pm - 11:56 pm
MOB
-
ORD
4h 39m1 stop
Delta Logo
5:25 am - 12:08 pm
ORD
-
MOB
6h 43m1 stop
$251Delta
Wed, Feb 18 - Sat, Feb 21
Delta Logo
5:51 pm - 11:59 pm
BTR
-
ORD
6h 08m1 stop
Delta Logo
5:30 am - 12:48 pm
ORD
-
BTR
7h 18m1 stop
$259Delta
Sat, Jan 17 - Fri, Jan 23
American Airlines Logo
2:23 pm - 8:39 pm
AEX
-
ORD
6h 16m1 stop
American Airlines Logo
3:23 pm - 10:59 pm
ORD
-
AEX
7h 36m1 stop
$268American Airlines
Sat, Jan 10 - Wed, Jan 14
United Airlines Logo
5:13 pm - 12:28 am
GPT
-
ORD
7h 15m1 stop
United Airlines Logo
5:40 am - 1:22 pm
ORD
-
GPT
7h 42m1 stop
$269United Airlines
Fri, Jan 16 - Sun, Jan 18

United Airlines flights from Mississippi to Chicago O'Hare Intl Airport

Our best United Airlines deals on Mississippi to Chicago O'Hare Intl Airport flight tickets
United Airlines
Feb 7
MEM4:54 pmMemphis
2h 01m
ORD6:55 pmChicago O'Hare Intl
Feb 14
ORD8:48 amChicago O'Hare Intl
2h 09m
MEM10:57 amMemphis
$210
Find similar
United Airlines
Jan 21
MEM9:55 amMemphis
2h 03m
ORD11:58 amChicago O'Hare Intl
Jan 24
ORD7:55 pmChicago O'Hare Intl
1h 59m
MEM9:54 pmMemphis
$212
Find similar
United Airlines
Jan 24
MEM9:55 amMemphis
2h 03m
ORD11:58 amChicago O'Hare Intl
Jan 31
ORD12:45 pmChicago O'Hare Intl
2h 00m
MEM2:45 pmMemphis
$231
Find similar

American Airlines flights from Mississippi to Chicago O'Hare Intl Airport

Our best American Airlines deals on Mississippi to Chicago O'Hare Intl Airport flight tickets
American Airlines
Mar 18
MOB10:41 amMobile
5h 14m
1 stop
ORD3:55 pmChicago O'Hare Intl
Apr 15
ORD5:00 amChicago O'Hare Intl
6h 47m
1 stop
MOB11:47 amMobile
$211
Find similar
American Airlines
Jan 21
MEM6:40 amMemphis
2h 08m
ORD8:48 amChicago O'Hare Intl
Jan 24
ORD6:54 amChicago O'Hare Intl
5h 41m
1 stop
MEM12:35 pmMemphis
$222
Find similar
American Airlines
Jan 29
MEM5:45 pmMemphis
2h 11m
ORD7:56 pmChicago O'Hare Intl
Feb 2
ORD8:10 amChicago O'Hare Intl
2h 07m
MEM10:17 amMemphis
$239
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Mississippi to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisChicago

MEM - ORD

MEMORD

Memphis

Sat 1/17

11:44 am-7:41 pm

1 stop7h 57m

Chicago O'Hare Intl

Sun 1/18

2:30 pm-1:04 pm

1 stop22h 34m

$181

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 1/21

11:44 am-10:41 am

1 stop22h 57m

Chicago O'Hare Intl

Wed 1/28

5:32 pm-7:28 pm

1 stop25h 56m

$186

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 1/21

11:44 am-10:41 am

1 stop22h 57m

Chicago O'Hare Intl

Sat 1/24

5:32 pm-7:28 pm

1 stop25h 56m

$190

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 1/21

7:30 am-9:27 am

Nonstop1h 57m

Chicago O'Hare Intl

Wed 1/28

3:35 pm-5:26 pm

Nonstop1h 51m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Thu 1/8

5:55 pm-10:39 pm

1 stop4h 44m

Chicago O'Hare Intl

Sun 1/11

5:50 am-5:00 pm

1 stop11h 10m

$197

MobileChicago

MOB - ORD

MOBORD

Mobile

Wed 3/18

10:41 am-3:55 pm

1 stop5h 14m

Chicago O'Hare Intl

Wed 4/15

5:00 am-11:47 am

1 stop6h 47m

$211

MobileChicago

MOB - ORD

MOBORD

Mobile

Wed 2/18

7:17 pm-11:56 pm

1 stop4h 39m

Chicago O'Hare Intl

Sat 2/21

5:25 am-12:08 pm

1 stop6h 43m

$251

Baton RougeChicago

BTR - ORD

BTRORD

Baton Rouge Ryan

Sat 1/17

5:51 pm-11:59 pm

1 stop6h 08m

Chicago O'Hare Intl

Fri 1/23

5:30 am-12:48 pm

1 stop7h 18m

$259

AlexandriaChicago

AEX - ORD

AEXORD

Alexandria

Sat 1/10

2:23 pm-8:39 pm

1 stop6h 16m

Chicago O'Hare Intl

Wed 1/14

3:23 pm-10:59 pm

1 stop7h 36m

$268

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

Fri 1/16

5:13 pm-12:28 am

1 stop7h 15m

Chicago O'Hare Intl

Sun 1/18

5:40 am-1:22 pm

1 stop7h 42m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Mississippi to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of January is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Mississippi averaging around $346.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Saturday when prices can be found for as low as $360. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Mississippi because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $622.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Mississippi in the evening is the least expensive time of day to depart. momondo users have found prices as low as $335 when looking at flights departing in the evening. Try not to purchase tickets in the afternoon because they tend to be around $500. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Mississippi to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Chicago O'Hare Intl Airport

Fastest flight time

1h 55m

Direct flights

Every day
The fastest flight from Mississippi to Chicago O'Hare Intl Airport takes 1h 55m
Direct flights go from Mississippi to Chicago O'Hare Intl Airport every day.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Chicago O'Hare Intl Airport?

    Prices for flights from Mississippi to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from Mississippi to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Mississippi to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Mississippi to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Mississippi to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Mississippi to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,067 reviews
Search American Airlines flights
DeltaPriceFrom $249Free CancellationRating
7.9
8,018 reviews
Search Delta flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Schaumburg
South Haven
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Janesville
Tinley Park
Aurora
Elgin
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Mississippi.

Can I find flights from Mississippi to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Mississippi to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Mississippi to Chicago?

Once all potential Mississippi to Chicago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Mississippi to Chicago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Chicago, momondo offers a useful price alert feature which will track prices for flights to Chicago from Mississippi and alert you when they change.

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