What is the cheapest airline that flies from Minneapolis St Paul to Panama?

United Airlines and American Airlines are the most popular carriers operating from Minneapolis St Paul to Panama

What airlines fly to Panama?

United Airlines, Delta and Copa Airlines are the top three most popular airlines that fly to Panama from Minneapolis according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama?

Prices for flights from Minneapolis St Paul Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama?

The number of operators available for flights from Minneapolis St Paul Airport to Panama is 4 as of October 2026.

How old do you have to be to fly from Minneapolis St Paul Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$437 Cheap Flights from Minneapolis to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Minneapolis to Panama

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:30 am - 7:38 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

11h 08m1 stop Houston George Bush Intcntl

4:41 pm - 10:56 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

19h 15m1 stop Houston George Bush Intcntl

$549United Airlines

Mon, Jan 11 - Tue, Jan 19

8:00 am - 7:38 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

10h 38m1 stop Houston George Bush Intcntl

4:41 pm - 10:57 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

19h 16m1 stop Houston George Bush Intcntl

$549United Airlines

Mon, Feb 22 - Mon, Mar 1

3:51 pm - 12:36 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

20h 45m2 stops Charlotte Douglas Miami

1:49 pm - 11:13 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

21h 24m2 stops Miami Philadelphia

$554American Airlines

Tue, Apr 6 - Wed, Apr 14

6:01 pm - 3:30 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

20h 29m2 stops Washington, D.C. Reagan-National Miami

2:47 pm - 10:55 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

21h 08m2 stops Miami Washington, D.C. Reagan-National

$554American Airlines

Mon, Feb 22 - Fri, Feb 26

7:30 am - 5:12 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 42m1 stop Houston George Bush Intcntl

4:41 pm - 7:53 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

28h 12m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$640Copa Airlines

Mon, Jan 11 - Thu, Jan 14

7:35 am - 8:02 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

11h 27m2 stops Chicago O'Hare Intl Newark

4:41 pm - 7:53 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

28h 12m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$640Copa Airlines

Mon, Jan 11 - Thu, Jan 14

4:26 pm - 9:45 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

28h 19m1 stop Atlanta Hartsfield-Jackson

8:00 am - 11:00 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

16h 00m1 stop Atlanta Hartsfield-Jackson

$764Delta

Mon, Dec 28 - Thu, Jan 7

6:00 pm - 9:45 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

26h 45m1 stop Atlanta Hartsfield-Jackson

8:00 am - 3:29 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

8h 29m1 stop Atlanta Hartsfield-Jackson

$764Delta

Wed, Dec 30 - Wed, Jan 6

6:00 am - 3:30 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 30m1 stop Miami

2:47 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

10h 12m1 stop Miami

$846GOL

Tue, Feb 23 - Sun, Feb 28

6:00 am - 3:30 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 30m1 stop Miami

2:47 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

10h 12m1 stop Miami

$912GOL

Sun, Feb 21 - Sun, Feb 28

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American Airlines flights from Minneapolis to Panama

Our best American Airlines deals on Minneapolis to Panama flight tickets

American Airlines

Feb 22

MSP7:52 pmMinneapolis St Paul

18h 38m

2 stops

PTY3:30 pmPanama City Tocumen Intl

Feb 28

PTY4:31 pmPanama City Tocumen Intl

21h 38m

2 stops

MSP1:09 pmMinneapolis St Paul

$589

American Airlines

Apr 3

MSP7:08 pmMinneapolis St Paul

19h 22m

2 stops

PTY2:30 pmPanama City Tocumen Intl

Apr 10

PTY1:49 pmPanama City Tocumen Intl

21h 24m

2 stops

MSP11:13 amMinneapolis St Paul

$629

American Airlines

Nov 29

MSP6:34 pmMinneapolis St Paul

19h 00m

2 stops

PTY2:34 pmPanama City Tocumen Intl

Dec 10

PTY3:13 pmPanama City Tocumen Intl

9h 22m

1 stop

MSP11:35 pmMinneapolis St Paul

$647

Copa Airlines flights from Minneapolis to Panama

Our best Copa Airlines deals on Minneapolis to Panama flight tickets

Copa Airlines

Jan 11

MSP7:30 amMinneapolis St Paul

8h 42m

1 stop

PTY5:12 pmPanama City Tocumen Intl

Jan 14

PTY4:41 pmPanama City Tocumen Intl

28h 12m

2 stops

MSP7:53 pmMinneapolis St Paul

$640

Copa Airlines

Jan 8

MSP9:45 amMinneapolis St Paul

9h 17m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Jan 14

PTY4:41 pmPanama City Tocumen Intl

28h 12m

2 stops

MSP7:53 pmMinneapolis St Paul

$650

Copa Airlines

Mar 27

MSP5:44 pmMinneapolis St Paul

10h 20m

1 stop

PTY4:04 amPanama City Tocumen Intl

Apr 2

PTY10:00 amPanama City Tocumen Intl

28h 22m

2 stops

MSP2:22 pmMinneapolis St Paul

$701

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/11

7:30 am-7:38 pm

1 stop11h 08m

Panama City Tocumen Intl

Tue 1/19

4:41 pm-10:56 am

1 stop19h 15m

$549

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 2/22

8:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Mon 3/1

4:41 pm-10:57 am

1 stop19h 16m

$549

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 4/6

3:51 pm-12:36 pm

2 stops20h 45m

Panama City Tocumen Intl

Wed 4/14

1:49 pm-11:13 am

2 stops21h 24m

$554

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 2/22

6:01 pm-3:30 pm

2 stops20h 29m

Panama City Tocumen Intl

Fri 2/26

2:47 pm-10:55 am

2 stops21h 08m

$554

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/11

7:30 am-5:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Thu 1/14

4:41 pm-7:53 pm

2 stops28h 12m

$640

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/11

7:35 am-8:02 pm

2 stops11h 27m

Panama City Tocumen Intl

Thu 1/14

4:41 pm-7:53 pm

2 stops28h 12m

$640

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 12/28

4:26 pm-9:45 pm

1 stop28h 19m

Panama City Tocumen Intl

Thu 1/7

8:00 am-11:00 pm

1 stop16h 00m

$764

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Wed 12/30

6:00 pm-9:45 pm

1 stop26h 45m

Panama City Tocumen Intl

Wed 1/6

8:00 am-3:29 pm

1 stop8h 29m

$764

Quickest round-trip

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 2/23

6:00 am-3:30 pm

1 stop8h 30m

Panama City Tocumen Intl

Sun 2/28

2:47 pm-11:59 pm

1 stop10h 12m

$846

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Sun 2/21

6:00 am-3:30 pm

1 stop8h 30m

Panama City Tocumen Intl

Sun 2/28

2:47 pm-11:59 pm

1 stop10h 12m

$912

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Minneapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of January is, on average, the cheapest month to fly to Panama from Minneapolis, with most prices found around $736. If you don’t want to visit Panama in January, then you should wait until April to fly from Minneapolis, when ticket prices are also cheap, with an average price of $741.

How far in advance should I book a flight from Minneapolis to Panama?

You are more likely to see cheaper flights to Panama from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $944 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Minneapolis for as low as $652 on momondo.

Cheap Minneapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama

Best Price Found	$437
Fastest flight time	8h 42m
Direct flights	None

The best one-way flight to Panama from Minneapolis in the past 72 hours is $437. The best round-trip flight deal from Minneapolis to Panama found on momondo in the last 72 hours is $549.

The fastest flight from Minneapolis to Panama takes 8h 42m

There are no direct flights from Minneapolis to Panama. There are no popular flight routes from Minneapolis to Panama.

Search flight deals

Frequently asked questions about flying from Minneapolis to Panama

When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama?
Prices for flights from Minneapolis St Paul Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama?
The number of operators available for flights from Minneapolis St Paul Airport to Panama is 4 as of October 2026.
How old do you have to be to fly from Minneapolis St Paul Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to Panama

Compare and see reviews for airlines that fly from Minneapolis to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $573	Free Cancellation	Rating 7.3 10,396 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $577	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $636	Free Cancellation	Rating 7.0 12,183 reviews	Search American Airlines flights
Delta	PriceFrom $704	Free Cancellation	Rating 7.8 8,659 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama?

It is quick and easy to find Minneapolis to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Minneapolis to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama?

momondo helps you find the best flight between Minneapolis and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Minneapolis to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Flights to Panama Cityfrom $517

Flights to Bocas del Torofrom $929

Flights to Davidfrom $485

Flights to Changuinola

Cheap flights from Minneapolis to Panama from $437

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Minneapolis to Panama

Our best American Airlines deals on Minneapolis to Panama flight tickets

Copa Airlines flights from Minneapolis to Panama

Our best Copa Airlines deals on Minneapolis to Panama flight tickets

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How to get the cheapest flight ticket from Minneapolis to Panama

What is the cheapest month to fly to Panama?

How far in advance should I book a flight from Minneapolis to Panama?

What is the cheapest airline that flies from Minneapolis St Paul to Panama?

What airlines fly to Panama?

Cheap Minneapolis to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Minneapolis to Panama

Best airlines flying from Minneapolis to Panama

Compare and see reviews for airlines that fly from Minneapolis to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Minneapolis flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year