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Cheap flights from Minneapolis to Panama from $355

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama departing on 5/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Minneapolis to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:50 am - 12:35 am
MSP
-
PTY
17h 45m
2 stops
Multiple Airlines Logo
4:25 am - 8:48 pm
PTY
-
MSP
16h 23m
2 stops
$648Multiple Airlines
Thu, Jun 4 - Mon, Jun 8
Multiple Airlines Logo
6:40 am - 12:35 am
MSP
-
PTY
17h 55m
2 stops
Multiple Airlines Logo
5:55 pm - 8:43 pm
PTY
-
MSP
26h 48m
2 stops
$681Multiple Airlines
Sat, May 30 - Fri, Jun 5
Delta Logo
5:15 am - 12:56 pm
MSP
-
PTY
7h 41m
1 stop
Delta Logo
2:21 pm - 12:21 am
PTY
-
MSP
10h 00m
1 stop
$705Delta
Thu, Sep 10 - Tue, Oct 13
United Airlines Logo
10:22 am - 7:31 pm
MSP
-
PTY
9h 09m
1 stop
United Airlines Logo
3:30 pm - 10:19 am
PTY
-
MSP
18h 49m
2 stops
$709United Airlines
Thu, Sep 10 - Tue, Oct 13
United Airlines Logo
10:14 am - 7:31 pm
MSP
-
PTY
9h 17m
1 stop
United Airlines Logo
3:30 pm - 10:54 am
PTY
-
MSP
19h 24m
1 stop
$718United Airlines
Tue, Aug 4 - Wed, Aug 12
American Airlines Logo
6:39 am - 2:10 pm
MSP
-
PTY
7h 31m
1 stop
American Airlines Logo
3:40 pm - 10:39 pm
PTY
-
MSP
30h 59m
1 stop
$722American Airlines
Wed, Sep 23 - Fri, Oct 2
Delta Logo
8:15 pm - 12:56 pm
MSP
-
PTY
16h 41m
1 stop
Delta Logo
2:21 pm - 9:10 am
PTY
-
MSP
18h 49m
1 stop
$730Delta
Thu, Oct 8 - Thu, Oct 15
Multiple Airlines Logo
2:40 pm - 5:22 pm
MSP
-
PTY
26h 42m
2 stops
Multiple Airlines Logo
6:34 pm - 3:05 pm
PTY
-
MSP
20h 31m
1 stop
$731Multiple Airlines
Sat, May 30 - Fri, Jun 5
United Airlines Logo
6:35 pm - 2:14 pm
MSP
-
PTY
19h 39m
2 stops
United Airlines Logo
10:00 am - 10:52 pm
PTY
-
MSP
12h 52m
1 stop
$734United Airlines
Sat, Oct 10 - Mon, Oct 19
Copa Airlines Logo
8:30 pm - 9:03 am
MSP
-
DAV
12h 33m
2 stops
Copa Airlines Logo
7:54 pm - 10:28 am
DAV
-
MSP
38h 34m
2 stops
$1,321Copa Airlines
Fri, Jul 17 - Fri, Jul 24

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Delta flights from Minneapolis to Panama

Our best Delta deals on Minneapolis to Panama flight tickets
Delta
Sep 10
MSP5:15 amMinneapolis St Paul
7h 41m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 13
PTY2:21 pmPanama City Tocumen Intl
10h 00m
1 stop
MSP12:21 amMinneapolis St Paul
$705
Delta
Oct 8
MSP8:15 pmMinneapolis St Paul
16h 41m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 15
PTY2:21 pmPanama City Tocumen Intl
18h 49m
1 stop
MSP9:10 amMinneapolis St Paul
$730
Delta
Oct 8
MSP8:15 pmMinneapolis St Paul
16h 41m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 19
PTY2:21 pmPanama City Tocumen Intl
10h 00m
1 stop
MSP12:21 amMinneapolis St Paul
$763

United Airlines flights from Minneapolis to Panama

Our best United Airlines deals on Minneapolis to Panama flight tickets
United Airlines
Sep 10
MSP10:22 amMinneapolis St Paul
9h 09m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Oct 13
PTY3:30 pmPanama City Tocumen Intl
18h 49m
2 stops
MSP10:19 amMinneapolis St Paul
$709
United Airlines
Aug 4
MSP10:14 amMinneapolis St Paul
9h 17m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Aug 12
PTY3:30 pmPanama City Tocumen Intl
19h 24m
1 stop
MSP10:54 amMinneapolis St Paul
$718
United Airlines
Oct 10
MSP6:35 pmMinneapolis St Paul
19h 39m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Oct 19
PTY10:00 amPanama City Tocumen Intl
12h 52m
1 stop
MSP10:52 pmMinneapolis St Paul
$734

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 6/4

6:50 am-12:35 am

2 stops17h 45m

Panama City Tocumen Intl

Mon 6/8

4:25 am-8:48 pm

2 stops16h 23m

$648

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 5/30

6:40 am-12:35 am

2 stops17h 55m

Panama City Tocumen Intl

Fri 6/5

5:55 pm-8:43 pm

2 stops26h 48m

$681
Quickest round-trip

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 9/10

5:15 am-12:56 pm

1 stop7h 41m

Panama City Tocumen Intl

Tue 10/13

2:21 pm-12:21 am

1 stop10h 00m

$705

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 9/10

10:22 am-7:31 pm

1 stop9h 09m

Panama City Tocumen Intl

Tue 10/13

3:30 pm-10:19 am

2 stops18h 49m

$709

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 8/4

10:14 am-7:31 pm

1 stop9h 17m

Panama City Tocumen Intl

Wed 8/12

3:30 pm-10:54 am

1 stop19h 24m

$718

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 9/23

6:39 am-2:10 pm

1 stop7h 31m

Panama City Tocumen Intl

Fri 10/2

3:40 pm-10:39 pm

1 stop30h 59m

$722

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 10/8

8:15 pm-12:56 pm

1 stop16h 41m

Panama City Tocumen Intl

Thu 10/15

2:21 pm-9:10 am

1 stop18h 49m

$730

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 5/30

2:40 pm-5:22 pm

2 stops26h 42m

Panama City Tocumen Intl

Fri 6/5

6:34 pm-3:05 pm

1 stop20h 31m

$731

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 10/10

6:35 pm-2:14 pm

2 stops19h 39m

Panama City Tocumen Intl

Mon 10/19

10:00 am-10:52 pm

1 stop12h 52m

$734

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

Fri 7/17

8:30 pm-9:03 am

2 stops12h 33m

David Enrique Malek

Fri 7/24

7:54 pm-10:28 am

2 stops38h 34m

$1,321

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Minneapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of March is, on average, the cheapest month to fly to Panama from Minneapolis, with most prices found around $724. If you don’t want to visit Panama in March, then you should wait until November to fly from Minneapolis, when ticket prices are also cheap, with an average price of $726.

How far in advance should I book a flight from Minneapolis to Panama?

You are more likely to see cheaper flights to Panama from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $828 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Minneapolis for as low as $355 on momondo.

Cheap Minneapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama

Fastest flight time

7h 58m

Direct flights

None
The fastest flight from Minneapolis to Panama takes 7h 58m
There are no direct flights from Minneapolis to Panama. There are no popular flight routes from Minneapolis to Panama.
Search flight deals

Frequently asked questions about flying from Minneapolis to Panama

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama?

    Prices for flights from Minneapolis St Paul Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to Panama

Compare and see reviews for airlines that fly from Minneapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $603Free CancellationRating
7.1
11,671 reviews
Search American Airlines flights
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,651 reviews
Search United Airlines flights
DeltaPriceFrom $613Free CancellationRating
7.9
8,459 reviews
Search Delta flights
Copa AirlinesPriceFrom $646Free CancellationRating
7.5
1,578 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama?

It is quick and easy to find Minneapolis to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Minneapolis to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama?

momondo helps you find the best flight between Minneapolis and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Minneapolis to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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