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Cheap flights from Minneapolis to Panama from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Minneapolis to Panama

Cheap round-trip flights

Multiple Airlines Logo
7:00 am - 7:46 pmMSP-PTY
12h 46m1 stop
Multiple Airlines Logo
8:57 am - 9:02 pmPTY-MSP
12h 05m1 stop
$495Multiple Airlines
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Fri, Oct 3 - Mon, Oct 6
Multiple Airlines Logo
7:00 am - 7:46 pmMSP-PTY
12h 46m1 stop
Multiple Airlines Logo
8:57 am - 9:39 pmPTY-MSP
12h 42m1 stop
$506Multiple Airlines
Find Deal
Fri, Oct 3 - Fri, Oct 10
Multiple Airlines Logo
5:45 am - 8:37 pmMSP-PTY
14h 52m2 stops
Multiple Airlines Logo
6:32 pm - 2:54 pmPTY-MSP
20h 22m1 stop
$542Multiple Airlines
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Wed, Oct 15 - Wed, Oct 22
Multiple Airlines Logo
7:00 am - 7:46 pmMSP-PTY
12h 46m1 stop
Multiple Airlines Logo
8:57 am - 7:27 pmPTY-MSP
10h 30m1 stop
$551Multiple Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
Delta Logo
5:15 am - 2:02 pmMSP-PTY
7h 47m1 stop
Delta Logo
3:27 pm - 9:14 amPTY-MSP
18h 47m1 stop
$603Delta
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Tue, Jan 13 - Thu, Jan 29
United Airlines Logo
7:35 am - 5:07 pmMSP-PTY
8h 32m1 stop
United Airlines Logo
4:41 pm - 10:33 amPTY-MSP
18h 52m2 stops
$608United Airlines
Find Deal
Mon, Jan 12 - Mon, Jan 26
Delta Logo
4:25 pm - 2:02 pmMSP-PTY
20h 37m1 stop
Delta Logo
3:27 pm - 9:14 amPTY-MSP
18h 47m1 stop
$615Delta
Find Deal
Sun, Jan 11 - Mon, Jan 26
American Airlines Logo
5:04 pm - 3:35 pmMSP-PTY
21h 31m2 stops
American Airlines Logo
4:40 pm - 12:55 pmPTY-MSP
21h 15m2 stops
$628American Airlines
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Mon, Jan 5 - Sat, Jan 24
United Airlines Logo
7:01 am - 8:02 pmMSP-PTY
12h 01m1 stop
United Airlines Logo
4:41 pm - 10:33 amPTY-MSP
18h 52m2 stops
$633United Airlines
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Fri, Jan 16 - Thu, Jan 29
American Airlines Logo
5:48 am - 1:10 pmMSP-PTY
30h 22m1 stop
American Airlines Logo
4:40 pm - 12:35 amPTY-MSP
8h 55m1 stop
$638American Airlines
Find Deal
Mon, Jan 5 - Sat, Jan 24

American Airlines flights from Minneapolis to Panama

Our best American Airlines deals on Minneapolis to Panama flight tickets
American Airlines
Jan 5
MSP5:04 pmMinneapolis St Paul
21h 31m
2 stops
PTY3:35 pmPanama City Tocumen Intl
Jan 24
PTY4:40 pmPanama City Tocumen Intl
21h 15m
2 stops
MSP12:55 pmMinneapolis St Paul
$628
Find similar
American Airlines
Jan 5
MSP5:48 amMinneapolis St Paul
30h 22m
1 stop
PTY1:10 pmPanama City Tocumen Intl
Jan 24
PTY4:40 pmPanama City Tocumen Intl
8h 55m
1 stop
MSP12:35 amMinneapolis St Paul
$638
Find similar
American Airlines
Jan 12
MSP6:30 amMinneapolis St Paul
8h 05m
1 stop
PTY3:35 pmPanama City Tocumen Intl
Feb 28
PTY4:40 pmPanama City Tocumen Intl
8h 53m
1 stop
MSP12:33 amMinneapolis St Paul
$643
Find similar

Delta flights from Minneapolis to Panama

Our best Delta deals on Minneapolis to Panama flight tickets
Delta
Jan 13
MSP5:15 amMinneapolis St Paul
7h 47m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Jan 29
PTY3:27 pmPanama City Tocumen Intl
18h 47m
1 stop
MSP9:14 amMinneapolis St Paul
$603
Find similar
Delta
Jan 11
MSP4:25 pmMinneapolis St Paul
20h 37m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Jan 26
PTY3:27 pmPanama City Tocumen Intl
18h 47m
1 stop
MSP9:14 amMinneapolis St Paul
$615
Find similar
Delta
Jan 15
MSP4:25 pmMinneapolis St Paul
20h 37m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Jan 26
PTY3:27 pmPanama City Tocumen Intl
18h 47m
1 stop
MSP9:14 amMinneapolis St Paul
$640
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 10/3

7:00 am-7:46 pm

1 stop12h 46m

Panama City Tocumen Intl

Mon 10/6

8:57 am-9:02 pm

1 stop12h 05m

$495

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 10/3

7:00 am-7:46 pm

1 stop12h 46m

Panama City Tocumen Intl

Fri 10/10

8:57 am-9:39 pm

1 stop12h 42m

$506

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 10/15

5:45 am-8:37 pm

2 stops14h 52m

Panama City Tocumen Intl

Wed 10/22

6:32 pm-2:54 pm

1 stop20h 22m

$542

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 10/3

7:00 am-7:46 pm

1 stop12h 46m

Panama City Tocumen Intl

Sun 10/5

8:57 am-7:27 pm

1 stop10h 30m

$551

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 1/13

5:15 am-2:02 pm

1 stop7h 47m

Panama City Tocumen Intl

Thu 1/29

3:27 pm-9:14 am

1 stop18h 47m

$603

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 1/12

7:35 am-5:07 pm

1 stop8h 32m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-10:33 am

2 stops18h 52m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 1/11

4:25 pm-2:02 pm

1 stop20h 37m

Panama City Tocumen Intl

Mon 1/26

3:27 pm-9:14 am

1 stop18h 47m

$615

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 1/5

5:04 pm-3:35 pm

2 stops21h 31m

Panama City Tocumen Intl

Sat 1/24

4:40 pm-12:55 pm

2 stops21h 15m

$628

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 1/16

7:01 am-8:02 pm

1 stop12h 01m

Panama City Tocumen Intl

Thu 1/29

4:41 pm-10:33 am

2 stops18h 52m

$633

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 1/5

5:48 am-1:10 pm

1 stop30h 22m

Panama City Tocumen Intl

Sat 1/24

4:40 pm-12:35 am

1 stop8h 55m

$638

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Minneapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of July is, on average, the cheapest month to fly to Panama from Minneapolis, with most prices found around $693. If you don’t want to visit Panama in July, then you should wait until January to fly from Minneapolis, when ticket prices are also cheap, with an average price of $768.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Minneapolis. The lowest ticket price found for a Tuesday departure recently was $757. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Minneapolis to Panama for around $861.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Minneapolis to Panama when you can find flight prices for as low as $746. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $817 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $858 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Minneapolis for as low as $695 on momondo.

Cheap Minneapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama

Direct flights

None
There are no direct flights from Minneapolis to Panama. There are no popular flight routes from Minneapolis to Panama.
Search flight deals

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama?

    Prices for flights from Minneapolis St Paul Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to Panama

Compare and see reviews for airlines that fly from Minneapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $562Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $644Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $674Free CancellationRating
7.9
7,961 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama?

It is quick and easy to find Minneapolis to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Minneapolis to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama?

momondo helps you find the best flight between Minneapolis and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Minneapolis to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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