Cheap flights from Mexico City to Cartagena from $169

In general, April is the cheapest month to fly from Mexico City to Cartagena. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $372. If you’re not able to fly to Cartagena in April, then February is your next best option. Flight prices from Mexico City to Cartagena during February average around $375.

According to our data, Monday is the cheapest day to fly to Cartagena from Mexico City. The lowest ticket price found for a Monday departure recently was $409. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Cartagena on Friday is $620.

Fly from Mexico City Benito Juarez to Cartagena Rafael Nunez for the best Mexico City Benito Juarez - Cartagena Rafael Nunez flight prices

You are more likely to see cheaper flights to Cartagena from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cartagena for around $408 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cartagena from Mexico City for as low as $343 on momondo.

There are 3 cabin classes available to choose from on Mexico City to Cartagena flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Mexico City to Cartagena.

Copa Airlines and Avianca are the most popular carriers operating from Mexico City Benito Juarez to Cartagena Rafael Nunez

Aeromexico, Copa Airlines and Avianca are the top three most popular airlines that fly to Cartagena from Mexico City according to our data. Aeromexico is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Cartagena. Keep in mind that there are 4 different airlines that fly to Cartagena on a routine basis, so you have a few additional options to choose from.

Historically, on average around 7% of flights between Mexico City and Cartagena have experienced a delay on any given week. The average delay length over the past 12 months has been 156 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Tuesday has historically seen more delays on average compared to the rest of the week.

According to our data, Aeromexico have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

Bogotá (BOG) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

Flights via Bogotá (BOG) offer the lowest average round-trip price of $623.

Flights connecting via Panama City (PTY) have the shortest average one-way travel time: 7h 09m.

Panama City (PTY) has the shortest average layover time for this route: 2h 24m.

1 flights are operational daily from Mexico City to Cartagena as of June 2026. The most popular departure time for this route is 9:00AM, with 100% of flights per day taking off at noon.

12 flights are operational weekly from Mexico City to Cartagena as of June 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.