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Cheap flights from Louisville to Panama from $300

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama departing on 7/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:25 am - 6:37 pm
SDF
-
PTY
12h 12m
1 stop
United Airlines Logo
9:45 am - 10:59 pm
PTY
-
SDF
12h 14m
1 stop
$629United Airlines
Fri, Aug 21 - Fri, Sep 11
Delta Logo
6:00 am - 12:55 pm
SDF
-
PTY
7h 55m
1 stop
Delta Logo
2:20 pm - 8:46 am
PTY
-
SDF
17h 26m
1 stop
$631Delta
Fri, Aug 7 - Thu, Aug 27
United Airlines Logo
7:25 am - 2:14 pm
SDF
-
PTY
7h 49m
1 stop
United Airlines Logo
3:30 pm - 1:11 pm
PTY
-
SDF
20h 41m
2 stops
$633United Airlines
Fri, Aug 21 - Tue, Sep 8
United Airlines Logo
7:15 am - 6:37 pm
SDF
-
PTY
12h 22m
2 stops
United Airlines Logo
3:30 pm - 1:11 pm
PTY
-
SDF
20h 41m
2 stops
$635United Airlines
Fri, Aug 7 - Mon, Aug 24
United Airlines Logo
7:55 pm - 4:12 pm
SDF
-
PTY
21h 17m
2 stops
United Airlines Logo
7:55 am - 11:59 pm
PTY
-
SDF
15h 04m
2 stops
$637United Airlines
Sat, Aug 1 - Fri, Aug 7
American Airlines Logo
6:00 pm - 12:52 pm
SDF
-
PTY
19h 52m
2 stops
American Airlines Logo
1:52 pm - 12:11 pm
PTY
-
SDF
21h 19m
2 stops
$638American Airlines
Fri, Oct 16 - Sun, Oct 25
Delta Logo
1:17 pm - 12:55 pm
SDF
-
PTY
24h 38m
1 stop
Delta Logo
2:20 pm - 8:46 am
PTY
-
SDF
17h 26m
1 stop
$639Delta
Thu, Aug 6 - Thu, Aug 27
United Airlines Logo
11:44 am - 7:31 pm
SDF
-
PTY
8h 47m
1 stop
United Airlines Logo
3:30 pm - 10:15 pm
PTY
-
SDF
29h 45m
1 stop
$640United Airlines
Tue, Jul 21 - Sat, Aug 15
United Airlines Logo
6:15 am - 2:14 pm
SDF
-
PTY
8h 59m
1 stop
United Airlines Logo
10:55 pm - 10:54 pm
PTY
-
SDF
22h 59m
1 stop
$642United Airlines
Fri, Aug 7 - Sun, Aug 9
Delta Logo
7:05 am - 12:55 pm
SDF
-
PTY
6h 50m
1 stop
Delta Logo
2:20 pm - 12:34 am
PTY
-
SDF
9h 14m
1 stop
$647Delta
Wed, Aug 5 - Fri, Aug 28

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American Airlines flights from Louisville to Panama

Our best American Airlines deals on Louisville to Panama flight tickets
American Airlines
Oct 16
SDF6:00 pmLouisville Intl
19h 52m
2 stops
PTY12:52 pmPanama City Tocumen Intl
Oct 25
PTY1:52 pmPanama City Tocumen Intl
21h 19m
2 stops
SDF12:11 pmLouisville Intl
$638
American Airlines
Jul 21
SDF8:05 pmLouisville Intl
17h 09m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Aug 15
PTY1:39 pmPanama City Tocumen Intl
22h 10m
2 stops
SDF12:49 pmLouisville Intl
$665
American Airlines
Jul 21
SDF12:00 pmLouisville Intl
25h 14m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Aug 15
PTY1:39 pmPanama City Tocumen Intl
21h 28m
2 stops
SDF12:07 pmLouisville Intl
$666

United Airlines flights from Louisville to Panama

Our best United Airlines deals on Louisville to Panama flight tickets
United Airlines
Aug 21
SDF7:25 amLouisville Intl
12h 12m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 11
PTY9:45 amPanama City Tocumen Intl
12h 14m
1 stop
SDF10:59 pmLouisville Intl
$629
United Airlines
Aug 21
SDF7:25 amLouisville Intl
7h 49m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Sep 8
PTY3:30 pmPanama City Tocumen Intl
20h 41m
2 stops
SDF1:11 pmLouisville Intl
$633
United Airlines
Aug 7
SDF9:00 amLouisville Intl
20h 04m
2 stops
PTY4:04 amPanama City Tocumen Intl
Aug 29
PTY3:30 pmPanama City Tocumen Intl
17h 08m
2 stops
SDF9:38 amLouisville Intl
$635

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/21

7:25 am-6:37 pm

1 stop12h 12m

Panama City Tocumen Intl

Fri 9/11

9:45 am-10:59 pm

1 stop12h 14m

$629

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/7

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 8/27

2:20 pm-8:46 am

1 stop17h 26m

$631

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/21

7:25 am-2:14 pm

1 stop7h 49m

Panama City Tocumen Intl

Tue 9/8

3:30 pm-1:11 pm

2 stops20h 41m

$633

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/7

7:15 am-6:37 pm

2 stops12h 22m

Panama City Tocumen Intl

Mon 8/24

3:30 pm-1:11 pm

2 stops20h 41m

$635

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 8/1

7:55 pm-4:12 pm

2 stops21h 17m

Panama City Tocumen Intl

Fri 8/7

7:55 am-11:59 pm

2 stops15h 04m

$637

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 10/16

6:00 pm-12:52 pm

2 stops19h 52m

Panama City Tocumen Intl

Sun 10/25

1:52 pm-12:11 pm

2 stops21h 19m

$638

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 8/6

1:17 pm-12:55 pm

1 stop24h 38m

Panama City Tocumen Intl

Thu 8/27

2:20 pm-8:46 am

1 stop17h 26m

$639

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 7/21

11:44 am-7:31 pm

1 stop8h 47m

Panama City Tocumen Intl

Sat 8/15

3:30 pm-10:15 pm

1 stop29h 45m

$640

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/7

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Sun 8/9

10:55 pm-10:54 pm

1 stop22h 59m

$642
Quickest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 8/5

7:05 am-12:55 pm

1 stop6h 50m

Panama City Tocumen Intl

Fri 8/28

2:20 pm-12:34 am

1 stop9h 14m

$647

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Louisville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of May is, on average, the cheapest month to fly to Panama from Louisville, with most prices found around $175. If you don’t want to visit Panama in May, then you should wait until February to fly from Louisville, when ticket prices are also cheap, with an average price of $430.

Can stopping save me money on Louisville to Panama flights?

You could potentially save up to 20% on your flight if you consider stops on a Louisville to Panama flight.

Cheap Louisville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama

Fastest flight time

7h 49m

Direct flights

None
The fastest flight from Louisville to Panama takes 7h 49m
There are no direct flights from Louisville to Panama. There are no popular flight routes from Louisville to Panama.
Search flight deals

Frequently asked questions about flying from Louisville to Panama

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama?

    Prices for flights from Louisville Intl Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama?

  • How old do you have to be to fly from Louisville Intl Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Panama

Compare and see reviews for airlines that fly from Louisville to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $430Free CancellationRating
7.4
9,938 reviews
Search United Airlines flights
American AirlinesPriceFrom $434Free CancellationRating
7.1
11,784 reviews
Search American Airlines flights
DeltaPriceFrom $558Free CancellationRating
7.8
8,453 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama?

It is quick and easy to find Louisville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Louisville to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Louisville with this policy.

How can momondo help me find flights from Louisville to Panama?

Once you have performed a search for Louisville to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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