What is the cheapest airline that flies from Louisville Intl to Panama?

American Airlines and United Airlines are the most popular carriers operating from Louisville Intl to Panama

What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from Louisville according to our data. United Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Louisville Intl Airport to Panama?

Prices for flights from Louisville Intl Airport to Panama refresh daily.

How many operators does momondo search for flights from Louisville Intl Airport to Panama?

There are 3 operators available for flights from Louisville Intl Airport to Panama as of August 2026.

How old do you have to be to fly from Louisville Intl Airport to Panama?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$322 Cheap Flights from Louisville to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:05 am - 12:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

6h 54m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

8h 35m1 stop Atlanta Hartsfield-Jackson

$681Delta

Thu, Oct 15 - Thu, Oct 29

7:05 am - 12:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

6h 54m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

8h 35m1 stop Atlanta Hartsfield-Jackson

$681Delta

Thu, Oct 15 - Mon, Oct 19

6:15 am - 7:31 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

14h 16m1 stop Newark

9:30 am - 11:30 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

13h 00m1 stop Newark

$681United Airlines

Mon, Oct 19 - Mon, Oct 26

11:15 am - 7:02 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

8h 47m1 stop Newark

10:00 am - 11:30 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

13h 30m1 stop Newark

$681United Airlines

Wed, Oct 28 - Wed, Nov 4

6:15 am - 7:31 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

14h 16m1 stop Newark

9:45 am - 8:13 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

9h 28m1 stop Newark

$681United Airlines

Mon, Oct 12 - Thu, Oct 15

8:18 pm - 1:02 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

17h 44m2 stops Charlotte Douglas Miami

2:02 pm - 9:32 amPTY Panama City Tocumen Intl-SDF Louisville Intl

18h 30m2 stops Miami Chicago O'Hare Intl

$685American Airlines

Mon, Oct 12 - Thu, Oct 15

5:19 pm - 1:02 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

20h 43m2 stops Chicago O'Hare Intl Miami

2:02 pm - 11:39 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

8h 37m1 stop Miami

$685American Airlines

Mon, Oct 12 - Thu, Oct 15

11:06 am - 12:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

26h 53m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 8:57 amPTY Panama City Tocumen Intl-SDF Louisville Intl

17h 33m1 stop Atlanta Hartsfield-Jackson

$703Delta

Thu, Oct 8 - Wed, Oct 14

6:15 am - 7:31 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

14h 16m1 stop Newark

10:00 am - 7:55 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

8h 55m1 stop Houston George Bush Intcntl

$767Copa Airlines

Sat, Oct 3 - Tue, Oct 6

7:00 am - 7:31 pmSDF Louisville Intl-PTY Panama City Tocumen Intl

13h 31m2 stops Chicago O'Hare Intl Newark

9:45 am - 8:13 pmPTY Panama City Tocumen Intl-SDF Louisville Intl

9h 28m1 stop Newark

$771Copa Airlines

Tue, Oct 6 - Sat, Oct 10

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United Airlines flights from Louisville to Panama

Our best United Airlines deals on Louisville to Panama flight tickets

United Airlines

Oct 28

SDF11:15 amLouisville Intl

8h 47m

1 stop

PTY7:02 pmPanama City Tocumen Intl

Nov 4

PTY10:00 amPanama City Tocumen Intl

13h 30m

1 stop

SDF11:30 pmLouisville Intl

$681

United Airlines

Oct 28

SDF11:15 amLouisville Intl

8h 47m

1 stop

PTY7:02 pmPanama City Tocumen Intl

Nov 4

PTY8:55 amPanama City Tocumen Intl

13h 35m

2 stops

SDF10:30 pmLouisville Intl

$685

United Airlines

Oct 18

SDF6:30 pmLouisville Intl

26h 01m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Oct 21

PTY9:45 amPanama City Tocumen Intl

12h 56m

1 stop

SDF11:41 pmLouisville Intl

$691

American Airlines flights from Louisville to Panama

Our best American Airlines deals on Louisville to Panama flight tickets

American Airlines

Oct 16

SDF8:18 pmLouisville Intl

17h 44m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 25

PTY2:02 pmPanama City Tocumen Intl

21h 06m

2 stops

SDF12:08 pmLouisville Intl

$718

American Airlines

Oct 5

SDF6:00 pmLouisville Intl

20h 02m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 11

PTY2:02 pmPanama City Tocumen Intl

26h 18m

2 stops

SDF5:20 pmLouisville Intl

$724

American Airlines

Sep 17

SDF4:48 pmLouisville Intl

20h 28m

2 stops

PTY12:16 pmPanama City Tocumen Intl

Sep 21

PTY1:16 pmPanama City Tocumen Intl

9h 28m

1 stop

SDF11:44 pmLouisville Intl

$726

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Thu 10/15

7:05 am-12:59 pm

1 stop6h 54m

Panama City Tocumen Intl

Thu 10/29

2:24 pm-11:59 pm

1 stop8h 35m

$681

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Thu 10/15

7:05 am-12:59 pm

1 stop6h 54m

Panama City Tocumen Intl

Mon 10/19

2:24 pm-11:59 pm

1 stop8h 35m

$681

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Mon 10/19

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Mon 10/26

9:30 am-11:30 pm

1 stop13h 00m

$681

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Wed 10/28

11:15 am-7:02 pm

1 stop8h 47m

Panama City Tocumen Intl

Wed 11/4

10:00 am-11:30 pm

1 stop13h 30m

$681

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Mon 10/12

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Thu 10/15

9:45 am-8:13 pm

1 stop9h 28m

$681

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Mon 10/12

8:18 pm-1:02 pm

2 stops17h 44m

Panama City Tocumen Intl

Thu 10/15

2:02 pm-9:32 am

2 stops18h 30m

$685

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Mon 10/12

5:19 pm-1:02 pm

2 stops20h 43m

Panama City Tocumen Intl

Thu 10/15

2:02 pm-11:39 pm

1 stop8h 37m

$685

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Thu 10/8

11:06 am-12:59 pm

1 stop26h 53m

Panama City Tocumen Intl

Wed 10/14

2:24 pm-8:57 am

1 stop17h 33m

$703

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Sat 10/3

6:15 am-7:31 pm

1 stop14h 16m

Panama City Tocumen Intl

Tue 10/6

10:00 am-7:55 pm

1 stop8h 55m

$767

LouisvillePanama City

SDF Louisville Intl - PTY Panama City Tocumen Intl

SDFPTY

Louisville Intl

Tue 10/6

7:00 am-7:31 pm

2 stops13h 31m

Panama City Tocumen Intl

Sat 10/10

9:45 am-8:13 pm

1 stop9h 28m

$771

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Louisville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of February is, on average, the cheapest month to fly to Panama from Louisville, with most prices found around $430. If you don’t want to visit Panama in February, then you should wait until April to fly from Louisville, when ticket prices are also cheap, with an average price of $481.

Can stopping save me money on Louisville to Panama flights?

You could potentially save up to 31% on your flight if you consider stops on a Louisville to Panama flight.

Cheap Louisville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama

Best Price Found	$322
Fastest flight time	6h 53m
Direct flights	None

The best one-way flight to Panama from Louisville in the past 72 hours is $322. The best round-trip flight deal from Louisville to Panama found on momondo in the last 72 hours is $681.

The fastest flight from Louisville to Panama takes 6h 53m

There are no direct flights from Louisville to Panama. There are no popular flight routes from Louisville to Panama.

Search flight deals

Frequently asked questions about flying from Louisville to Panama

When did momondo last update prices for flights from Louisville Intl Airport to Panama?
Prices for flights from Louisville Intl Airport to Panama refresh daily.
How many operators does momondo search for flights from Louisville Intl Airport to Panama?
There are 3 operators available for flights from Louisville Intl Airport to Panama as of August 2026.
How old do you have to be to fly from Louisville Intl Airport to Panama?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Panama

Compare and see reviews for airlines that fly from Louisville to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $430	Free Cancellation	Rating 7.4 10,115 reviews	Search United Airlines flights
American Airlines	PriceFrom $434	Free Cancellation	Rating 7.1 11,982 reviews	Search American Airlines flights
Delta	PriceFrom $558	Free Cancellation	Rating 7.8 8,517 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama?

It is quick and easy to find Louisville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Louisville to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Louisville with this policy.

How can momondo help me find flights from Louisville to Panama?

Once you have performed a search for Louisville to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

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Popular cities in Panama

Flights to Panama Cityfrom $483

Flights to Bocas del Torofrom $1,130

Flights to Davidfrom $440

Flights to Changuinola

Cheap flights from Louisville to Panama from $322

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama departing on 10/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Louisville to Panama

Our best United Airlines deals on Louisville to Panama flight tickets

American Airlines flights from Louisville to Panama

Our best American Airlines deals on Louisville to Panama flight tickets

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See travel insights to Panama from

How to get the cheapest flight ticket from Louisville to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Louisville to Panama flights?

What is the cheapest airline that flies from Louisville Intl to Panama?

What airlines fly to Panama?

Cheap Louisville to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Louisville to Panama

Best airlines flying from Louisville to Panama

Compare and see reviews for airlines that fly from Louisville to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Louisville flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year