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Cheap flights from Louisville to Panama from $193

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:31 am - 2:20 pmSDF-PTY
8h 49m1 stop
American Airlines Logo
1:50 pm - 12:14 amPTY-SDF
9h 24m1 stop
$424American Airlines
Find Deal
Fri, Mar 20 - Wed, Apr 1
United Airlines Logo
8:30 am - 8:02 pmSDF-PTY
11h 32m1 stop
United Airlines Logo
4:41 pm - 5:37 pmPTY-SDF
24h 56m2 stops
$428United Airlines
Find Deal
Tue, Jan 6 - Wed, Jan 21
Delta Logo
7:00 am - 12:55 pmSDF-PTY
6h 55m1 stop
Delta Logo
2:20 pm - 10:32 pmPTY-SDF
7h 12m1 stop
$431Delta
Find Deal
Sat, May 2 - Tue, May 5
United Airlines Logo
9:31 am - 7:38 pmSDF-PTY
10h 07m1 stop
United Airlines Logo
8:55 am - 9:57 pmPTY-SDF
13h 02m1 stop
$433United Airlines
Find Deal
Wed, Dec 3 - Sun, Dec 7
United Airlines Logo
7:30 am - 7:31 pmSDF-PTY
13h 01m2 stops
United Airlines Logo
7:55 am - 8:14 pmPTY-SDF
11h 19m2 stops
$435United Airlines
Find Deal
Sat, May 2 - Tue, May 5
United Airlines Logo
9:31 am - 7:38 pmSDF-PTY
10h 07m1 stop
United Airlines Logo
8:55 am - 10:29 pmPTY-SDF
13h 34m2 stops
$437United Airlines
Find Deal
Wed, Dec 3 - Sun, Dec 7
United Airlines Logo
6:00 am - 7:38 pmSDF-PTY
13h 38m1 stop
United Airlines Logo
7:55 am - 9:30 pmPTY-SDF
12h 35m1 stop
$438United Airlines
Find Deal
Fri, Mar 6 - Fri, Mar 13
United Airlines Logo
6:00 am - 2:45 pmSDF-PTY
8h 45m1 stop
United Airlines Logo
4:41 pm - 9:59 pmPTY-SDF
29h 18m1 stop
$439United Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
American Airlines Logo
6:32 pm - 3:38 pmSDF-PTY
21h 06m2 stops
American Airlines Logo
4:50 pm - 10:02 amPTY-SDF
17h 12m2 stops
$440American Airlines
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Thu, Jan 15 - Sun, Jan 18
Copa Airlines Logo
10:50 am - 8:35 pmSDF-PTY
9h 45m1 stop
Copa Airlines Logo
8:10 am - 8:32 pmPTY-SDF
12h 22m1 stop
$1,300Copa Airlines
Find Deal
Fri, Dec 26 - Sun, Jan 4

American Airlines flights from Louisville to Panama

Our best American Airlines deals on Louisville to Panama flight tickets
American Airlines
Mar 20
SDF6:31 amLouisville Intl
8h 49m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Apr 1
PTY1:50 pmPanama City Tocumen Intl
9h 24m
1 stop
SDF12:14 amLouisville Intl
$424
Find similar
American Airlines
Jan 15
SDF6:32 pmLouisville Intl
21h 06m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Jan 18
PTY4:50 pmPanama City Tocumen Intl
17h 12m
2 stops
SDF10:02 amLouisville Intl
$440
Find similar
American Airlines
Jan 15
SDF6:32 pmLouisville Intl
21h 06m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Jan 18
PTY4:50 pmPanama City Tocumen Intl
18h 25m
1 stop
SDF11:15 amLouisville Intl
$450
Find similar

United Airlines flights from Louisville to Panama

Our best United Airlines deals on Louisville to Panama flight tickets
United Airlines
Jan 6
SDF8:30 amLouisville Intl
11h 32m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Jan 21
PTY4:41 pmPanama City Tocumen Intl
24h 56m
2 stops
SDF5:37 pmLouisville Intl
$428
Find similar
United Airlines
Dec 3
SDF9:31 amLouisville Intl
10h 07m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Dec 7
PTY8:55 amPanama City Tocumen Intl
13h 02m
1 stop
SDF9:57 pmLouisville Intl
$433
Find similar
United Airlines
May 2
SDF7:30 amLouisville Intl
13h 01m
2 stops
PTY7:31 pmPanama City Tocumen Intl
May 5
PTY7:55 amPanama City Tocumen Intl
11h 19m
2 stops
SDF8:14 pmLouisville Intl
$435
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 3/20

6:31 am-2:20 pm

1 stop8h 49m

Panama City Tocumen Intl

Wed 4/1

1:50 pm-12:14 am

1 stop9h 24m

$424

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 1/6

8:30 am-8:02 pm

1 stop11h 32m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-5:37 pm

2 stops24h 56m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/2

7:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Tue 5/5

2:20 pm-10:32 pm

1 stop7h 12m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 12/3

9:31 am-7:38 pm

1 stop10h 07m

Panama City Tocumen Intl

Sun 12/7

8:55 am-9:57 pm

1 stop13h 02m

$433

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/2

7:30 am-7:31 pm

2 stops13h 01m

Panama City Tocumen Intl

Tue 5/5

7:55 am-8:14 pm

2 stops11h 19m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 12/3

9:31 am-7:38 pm

1 stop10h 07m

Panama City Tocumen Intl

Sun 12/7

8:55 am-10:29 pm

2 stops13h 34m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 3/6

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Fri 3/13

7:55 am-9:30 pm

1 stop12h 35m

$438

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 1/15

6:00 am-2:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Sun 1/18

4:41 pm-9:59 pm

1 stop29h 18m

$439

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 1/15

6:32 pm-3:38 pm

2 stops21h 06m

Panama City Tocumen Intl

Sun 1/18

4:50 pm-10:02 am

2 stops17h 12m

$440

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 12/26

10:50 am-8:35 pm

1 stop9h 45m

Panama City Tocumen Intl

Sun 1/4

8:10 am-8:32 pm

1 stop12h 22m

$1,300

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Louisville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Louisville, with most prices found around $410. If you don’t want to visit Panama in September, then you should wait until May to fly from Louisville, when ticket prices are also cheap, with an average price of $423.

What is the cheapest day to depart on your flight to Panama?

According to our data, Monday is the cheapest day to fly to Panama from Louisville. The lowest ticket price found for a Monday departure recently was $395. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Louisville to Panama for around $551.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Louisville to Panama when you can find flight prices for as low as $365. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $474 per ticket.

Cheap Louisville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama

Direct flights

None
There are no direct flights from Louisville to Panama. There are no popular flight routes from Louisville to Panama.
Search flight deals

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama?

    Prices for flights from Louisville Intl Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama?

  • How old do you have to be to fly from Louisville Intl Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Panama

Compare and see reviews for airlines that fly from Louisville to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $351Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights
DeltaPriceFrom $392Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama?

It is quick and easy to find Louisville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Louisville to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Louisville with this policy.

How can momondo help me find flights from Louisville to Panama?

Once you have performed a search for Louisville to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

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