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Cheap flights from Louisville to Panama from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Panama

Cheap round-trip flights

Delta Logo
6:00 pm - 12:50 pmSDF-PTY
19h 50m1 stop
Delta Logo
2:05 pm - 11:56 pmPTY-SDF
8h 51m1 stop
$415Delta
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Mon, Sep 1 - Tue, Sep 9
American Airlines Logo
6:31 am - 2:31 pmSDF-PTY
9h 00m1 stop
American Airlines Logo
3:15 pm - 12:36 amPTY-SDF
8h 21m1 stop
$423American Airlines
Find Deal
Thu, Oct 2 - Thu, Oct 9
American Airlines Logo
7:35 pm - 2:31 pmSDF-PTY
19h 56m2 stops
American Airlines Logo
3:15 pm - 1:47 pmPTY-SDF
21h 32m2 stops
$428American Airlines
Find Deal
Thu, Oct 2 - Thu, Oct 9
United Airlines Logo
7:15 am - 6:37 pmSDF-PTY
12h 22m1 stop
United Airlines Logo
10:00 am - 9:54 pmPTY-SDF
10h 54m1 stop
$430United Airlines
Find Deal
Wed, Oct 8 - Sat, Oct 11
United Airlines Logo
7:15 am - 6:37 pmSDF-PTY
12h 22m1 stop
United Airlines Logo
10:00 am - 10:01 amPTY-SDF
23h 01m2 stops
$435United Airlines
Find Deal
Wed, Oct 8 - Sat, Oct 11
United Airlines Logo
9:40 am - 6:37 pmSDF-PTY
9h 57m1 stop
United Airlines Logo
3:30 pm - 10:02 amPTY-SDF
17h 32m2 stops
$437United Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 21
United Airlines Logo
7:20 pm - 2:14 pmSDF-PTY
19h 54m2 stops
United Airlines Logo
10:00 am - 10:01 amPTY-SDF
23h 01m2 stops
$444United Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
United Airlines Logo
3:37 pm - 2:14 pmSDF-PTY
23h 37m1 stop
United Airlines Logo
10:00 am - 9:54 pmPTY-SDF
10h 54m1 stop
$448United Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
United Airlines Logo
9:15 am - 7:38 pmSDF-PTY
10h 23m1 stop
United Airlines Logo
8:55 am - 9:57 pmPTY-SDF
13h 02m1 stop
$461United Airlines
Find Deal
Thu, Nov 6 - Mon, Nov 10
American Airlines Logo
8:06 pm - 2:30 pmSDF-PTY
19h 24m2 stops
American Airlines Logo
1:45 pm - 11:58 pmPTY-SDF
9h 13m1 stop
$470American Airlines
Find Deal
Mon, Sep 1 - Tue, Sep 9

American Airlines flights from Louisville to Panama

Our best American Airlines deals on Louisville to Panama flight tickets
American Airlines
Oct 2
SDF6:31 amLouisville Intl
9h 00m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Oct 9
PTY3:15 pmPanama City Tocumen Intl
8h 21m
1 stop
SDF12:36 amLouisville Intl
$423
Find similar
American Airlines
Oct 2
SDF7:35 pmLouisville Intl
19h 56m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 9
PTY3:15 pmPanama City Tocumen Intl
21h 32m
2 stops
SDF1:47 pmLouisville Intl
$428
Find similar
American Airlines
Sep 1
SDF8:06 pmLouisville Intl
19h 24m
2 stops
PTY2:30 pmPanama City Tocumen Intl
Sep 9
PTY1:45 pmPanama City Tocumen Intl
9h 13m
1 stop
SDF11:58 pmLouisville Intl
$470
Find similar

United Airlines flights from Louisville to Panama

Our best United Airlines deals on Louisville to Panama flight tickets
United Airlines
Aug 21
SDF7:00 amLouisville Intl
12h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Aug 25
PTY3:30 pmPanama City Tocumen Intl
24h 46m
2 stops
SDF5:16 pmLouisville Intl
$428
Find similar
United Airlines
Oct 8
SDF7:15 amLouisville Intl
12h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 11
PTY10:00 amPanama City Tocumen Intl
10h 54m
1 stop
SDF9:54 pmLouisville Intl
$430
Find similar
United Airlines
Aug 21
SDF7:20 amLouisville Intl
12h 17m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 25
PTY3:30 pmPanama City Tocumen Intl
29h 30m
1 stop
SDF10:00 pmLouisville Intl
$432
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 9/1

6:00 pm-12:50 pm

1 stop19h 50m

Panama City Tocumen Intl

Tue 9/9

2:05 pm-11:56 pm

1 stop8h 51m

$415

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 10/2

6:31 am-2:31 pm

1 stop9h 00m

Panama City Tocumen Intl

Thu 10/9

3:15 pm-12:36 am

1 stop8h 21m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 10/2

7:35 pm-2:31 pm

2 stops19h 56m

Panama City Tocumen Intl

Thu 10/9

3:15 pm-1:47 pm

2 stops21h 32m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 10/8

7:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Sat 10/11

10:00 am-9:54 pm

1 stop10h 54m

$430

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 10/8

7:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Sat 10/11

10:00 am-10:01 am

2 stops23h 01m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 9/11

9:40 am-6:37 pm

1 stop9h 57m

Panama City Tocumen Intl

Sun 9/21

3:30 pm-10:02 am

2 stops17h 32m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 10/4

7:20 pm-2:14 pm

2 stops19h 54m

Panama City Tocumen Intl

Sat 10/11

10:00 am-10:01 am

2 stops23h 01m

$444

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 10/4

3:37 pm-2:14 pm

1 stop23h 37m

Panama City Tocumen Intl

Sat 10/11

10:00 am-9:54 pm

1 stop10h 54m

$448

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 11/6

9:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Mon 11/10

8:55 am-9:57 pm

1 stop13h 02m

$461

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 9/1

8:06 pm-2:30 pm

2 stops19h 24m

Panama City Tocumen Intl

Tue 9/9

1:45 pm-11:58 pm

1 stop9h 13m

$470

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Louisville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Louisville, with most prices found around $416. If you don’t want to visit Panama in September, then you should wait until May to fly from Louisville, when ticket prices are also cheap, with an average price of $423.

What is the cheapest day to depart on your flight to Panama?

According to our data, Monday is the cheapest day to fly to Panama from Louisville. The lowest ticket price found for a Monday departure recently was $395. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Louisville to Panama for around $551.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Louisville to Panama when you can find flight prices for as low as $365. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $474 per ticket.

Cheap Louisville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama

Best Price Found

$188

Fastest flight time

6h 49m

Direct flights

None

Airports in Panama

1 airport
The best one-way flight to Panama from Louisville in the past 72 hours is $188. The best round-trip flight deal from Louisville to Panama found on momondo in the last 72 hours is $415.
The fastest flight from Louisville to Panama takes 6h 49m
There are no direct flights from Louisville to Panama. Popular non-direct route for this connection is Louisville Intl Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
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  • When did momondo last update prices for flights from Louisville Intl Airport to Panama?

    Prices for flights from Louisville Intl Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama?

  • How old do you have to be to fly from Louisville Intl Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Panama

Compare and see reviews for airlines that fly from Louisville to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $338Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $351Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights
DeltaPriceFrom $382Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama?

It is quick and easy to find Louisville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Louisville to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Louisville with this policy.

How can momondo help me find flights from Louisville to Panama?

Once you have performed a search for Louisville to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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