Cheap flights from Los Angeles to Palermo from $363

The cheapest month to fly to Palermo from Los Angeles is in November. Flight prices, which tend to average around $654, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Palermo from Los Angeles during April instead. Flights to Palermo in April, while not as cheap as those in November, still average around $684.

You are more likely to see cheaper flights to Palermo from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to Palermo for around $951 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Palermo from Los Angeles for as low as $699 on momondo.

You could potentially save up to 16% on your flight if you consider stops on a Los Angeles to Palermo flight.

As of July 2026, prices for Los Angeles to Palermo flights are approximately 54% more expensive when compared to flights at the same time last year.

United Airlines and SWISS are the most popular carriers operating from Los Angeles Los Angeles to Palermo Punta Raisi

ITA Airways, SWISS and Turkish Airlines are the top three most popular airlines that fly to Palermo from Los Angeles according to our data. ITA Airways is the first choice among our users, with 66% of people opting to fly with this airline when traveling to Palermo. Keep in mind that there are 6 different airlines that fly to Palermo on a routine basis, so you have a few additional options to choose from.

Rome (FCO) was the most common stop: 60% of momondo users choosing 1-stop flights on this route connected there.

Flights via Istanbul (IST) offer the lowest average round-trip price of $696.

Flights connecting via Zurich (ZRH) have the shortest average one-way travel time: 14h 13m.

Rome (FCO) has the shortest average layover time for this route: 1h 38m.