Cheap flights from Los Angeles to Palermo from $427

The cheapest month to fly to Palermo from Los Angeles is in November. Flight prices, which tend to average around $656, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of November, then book flights to Palermo from Los Angeles during March instead. Flights to Palermo in March, while not as cheap as those in November, still average around $670.

You are more likely to see cheaper flights to Palermo from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to Palermo for around $860 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Palermo from Los Angeles for as low as $694 on momondo.

You could potentially save up to 15% on your flight if you consider stops on a Los Angeles to Palermo flight.

As of April 2026, prices for Los Angeles to Palermo flights are approximately 48% cheaper when compared to flights at the same time last year.

Lufthansa and KLM are the most popular carriers operating from Los Angeles to Palermo Punta Raisi

ITA Airways, SWISS and Lufthansa are the top three most popular airlines that fly to Palermo from Los Angeles according to our data. ITA Airways is the first choice among our users, with 71% of people opting to fly with this airline when traveling to Palermo. Keep in mind that there are 5 different airlines that fly to Palermo on a routine basis, so you have a few additional options to choose from.

Rome (FCO) was the most common stop: 79% of momondo users choosing 1-stop flights on this route connected there.

Flights via Zurich (ZRH) offer the lowest average round-trip price of $656.

Flights connecting via Zurich (ZRH) have the shortest average one-way travel time: 14h 19m.

Zurich (ZRH) has the shortest average layover time for this route: 1h 16m.